Compounds > chloroquine

chloroquine and artenimol

chloroquine has been researched along with artenimol in 119 studies

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.52)18.7374
1990's5 (4.20)18.2507
2000's20 (16.81)29.6817
2010's73 (61.34)24.3611
2020's18 (15.13)2.80

Authors

AuthorsStudies
Albuquerque, IS; Burojević, J; D'Alessandro, S; Djurković-Djaković, O; Konstantinović, J; Machado, M; Pecic, S; Prudêncio, M; Sciotti, RJ; Šolaja, BA; Srbljanović, J; Štajner, T; Taramelli, D; Terzić, N; Tot, M; Verbić, T; Zlatović, M1
Avery, V; Derese, S; Deyou, T; Duffy, S; Erdélyi, M; Fitzpatrick, PA; Gruhonjic, A; Gumula, I; Heydenreich, M; Holleran, J; Landberg, G; Mumo, M; Pang, F; Rissanen, K; Yenesew, A1
Blake, LD; Burrows, JN; Casandra, D; Giarrusso, J; Kyle, DE; LaCrue, AN; Lichorowic, CL; Maignan, JR; Manetsch, R; Mutka, TS; Willis, PA1
Combrinck, J; de Kock, C; N'Da, DD; Smit, FJ; Smith, PJ; Zuma, NH1
Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S1
Blank, BR; Gut, J; Renslo, AR; Rosenthal, PJ1
Blake, LD; Burrows, JN; Casandra, D; Kyle, DE; LaCrue, AN; Lichorowic, CL; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Mutka, TS; Neelarapu, R; Willis, PA1
Avery, VM; Carroll, AR; Duffy, S; Robertson, LP; Wang, D; Wang, Y1
Çapcı Karagöz, A; Efferth, T; Friedrich, O; Gruber, L; Hahn, F; Hampel, F; Kappes, B; Klein, V; Leidenberger, M; Marschall, M; Reiter, C; Seo, EJ; Tsogoeva, SB1
Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB1
Avery, VM; Baell, JB; Ban, K; Beveridge, JG; Blundell, S; Charman, SA; Chavchich, M; Chiu, FCK; Creek, D; Cuellar, ME; Dahlin, JL; Diab, S; Dingjan, T; Duffy, S; Edstein, MD; Ellis, K; Fletcher, S; Harjani, JR; Huang, F; Lucantoni, L; Marfurt, J; Noviyanti, R; Price, RN; Ralph, SA; Shi, DH; Strasser, JM; Teguh, S; Walters, MA; Wirjanata, G; Xue, L1
Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Robertson, LP1
Das, D; Hong, J1
Avery, VM; Duffy, S; Erdélyi, M; Lindblad, S; Maeda, G; Munissi, JJE; Nyandoro, SS; Pelletier, J1
Bane, CE; Bayles, BR; Black, C; Butler, K; Caridha, D; Ceja, FG; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Mu, J; Nolan, C; Olmeda, R; Potter, B; Pou, S; Pybus, B; Rasmussen, SA; Read, L; Reynolds, KA; Riscoe, MK; Roncal, N; Rosenthal, PJ; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Tumwebaze, PK; Vesely, B; Vuong, C; Xie, L; Zeng, Q; Zhang, J; Zhang, P1
Arshadi, AK; Banks, R; Boonhok, R; Chakrabarti, D; Collins, J; Huang, G; Melendez, J; Miao, J; Min, H; Murillo Solano, C; Shaw, J; Yuan, Y1
Boonhok, R; Chakrabarti, D; Huang, G; Melendez, J; Miao, J; Min, H; Solano, CM; Yu-Alfonzo, S; Yuan, Y1
Avery, VM; Carroll, AR; Holland, DC; Kennedy, EK; Kleks, G1
Asakawa, AH; Brockmeyer, F; Casandra, D; Huang, L; Kyle, DE; LaCrue, AN; Maher, SP; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Padin-Irizarry, V; Parvatkar, PT; Sakhno, YI; Zhao, Y1
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G1
Basilico, N; Biagini, GA; Hasebe, T; Hong, WD; Leung, SC; Nixon, GL; O'Neill, PM; Onuma, K; Parapini, S; Taramelli, D; Ward, SA; Woodley, CM1
Boonlarppradab, C; Choowong, W; Kornsakulkarn, J; Saepua, S; Suriyachadkun, C; Thongpanchang, C1
Klayman, DL; Lee, M; Lin, AJ1
Brossi, A; Buchs, P; Dominguez Gerpe, L; Flippen-Anderson, JL; Luo, XD; Milhous, W; Peters, W; Venugopalan, B; Yeh, HJ1
Avery, MA; Bandyopadhyaya, AK; Desai, PV; Furtado, MM; Muraleedharan, KM; Tekwani, BL1
Brun, R; Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Karle, JM; Matile, H; Santo Tomas, J; Scheurer, C; Scorneaux, B; Snyder, C; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S1
Fukuda, M; Jongsakul, K; Knirsch, C; Krudsood, S; Leowattana, W; Looareesuwan, S; Miller, RS; Noedl, H; Ohrt, C; Sriwichai, S; Tangpukdee, N; Thanachartwet, W; Yingyuen, K1
Adagu, IS; Fivelman, QL; Warhurst, DC1
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y1
Johnson, DJ; Krudsood, S; Looareesuwan, S; Muangnoicharoen, S; Ward, SA1
Almeras, L; Amalvict, R; Baret, E; Briolant, S; Fusaï, T; Henry, M; Parquet, V; Pradines, B; Rogier, C; Torrentino-Madamet, M1
Masseno, V; Muriithi, S; Nzila, A1
Fuehrer, HP; Haque, R; Hofecker, V; Khan, WA; Ley, B; Noedl, H; Siedl, A; Starzengruber, P; Thriemer, K; Wernsdorfer, WH1
Andrianaranjaka, V; Andriantsoanirina, V; Bouchier, C; Durand, R; Jahevitra, M; Ménard, D; Mercereau-Puijalon, O; Rabarijaona, LP; Rabearimanana, S; Radrianjafy, R; Randriantsoa, T; Rason, MA; Ratsimbasoa, A; Tichit, M1
Abdirahman, A; Borrmann, S; Bull, P; Diriye, A; Kiara, SM; Marsh, K; Mwai, L; Nzila, A; Pole, L; Rippert, A1
Ahmed, SA; Elsohly, MA; Galal, AM; Gul, W; Jacob, MR; Khan, SI; Radwan, MM; Ross, SA; Slade, D; Tekwani, BL1
Brun, R; Charman, SA; Charman, WN; Chollet, J; Creek, DJ; Dong, Y; Dorn, A; Koltun, M; Matile, H; Morizzi, J; Padmanilayam, M; Santo Tomas, J; Scheurer, C; Snyder, C; Sriraghavan, K; Tang, Y; Urwyler, H; Vennerstrom, JL; Wang, X; Wittlin, S1
Charman, SA; Charman, WN; Chiu, FC; Chollet, J; Dong, Y; Dorn, A; Johnson, LM; Matile, H; Morizzi, J; Scheurer, C; Snyder, C; Tang, Y; Tomas, JS; Urwyler, H; Vennerstrom, JL; Wittlin, S; Zhou, L1
Greenhouse, B; Joloba, M; Kiggundu, M; Nanyunja, S; Nsobya, SL; Rosenthal, PJ1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Borrmann, S; Kiara, SM; Mwai, L; Nzila, A; Ochola, LI; Ohuma, E; Okombo, J; Pole, L; Rono, J1
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA1
Amalvict, R; Baret, E; Briolant, S; Didillon, E; Henry, M; Oeuvray, C; Pradines, B; Rogier, C1
Breytenbach, JC; Lategan, CA; Lombard, MC; N'Da, DD; Smith, PJ2
Chibale, K; Feng, TS; Guantai, EM; Hoppe, HC; Nell, MJ; van Rensburg, CE1
Cross, RM; Kyle, DE; Luong, L; Maignan, JR; Manetsch, R; Mutka, TS; Sargent, J1
Cross, RM; Kyle, DE; Luong, L; Manetsch, R; Mutka, TS; Namelikonda, NK1
Breytenbach, JC; Cloete, TT; Kock, Cd; N'da, DD; Smith, PJ; Wilma Breytenbach, J1
Aminake, MN; Chibale, K; de Kock, C; Grobler, A; Hans, R; Kirschner, M; Kumar, V; Mahajan, A; Pradel, G; Rethwilm, A; Smith, PJ; Taylor, D; Wiesner, L1
Biamonte, MA; Le Roch, KG; Wanner, J1
Avery, VM; Sykes, ML1
Amewu, RK; Burrell-Saward, H; Chadwick, J; Hussain, A; Janneh, O; Miguel, C; O'Neill, PM; Panda, S; Rinki, R; Vivas, L; Ward, SA1
Chibale, K; Gut, J; Njogu, PM; Rosenthal, PJ1
Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L1
Birkholtz, LM; N'Da, DD; Smit, FJ; van Biljon, RA1
Battistuzzi, G; Giannini, G; Vignola, D1
Efferth, T; Friedrich, O; Fröhlich, T; Gruber, L; Hutterer, C; Kappes, B; Marschall, M; Reiter, C; Tsogoeva, SB; Voigtländer, C1
Beswick, P; Choowongkomon, K; Chuckowree, I; Gleeson, MP; Hannongbua, S; Horata, N; Obounchoey, P; Phuangsawai, O; Ratanabunyong, S; Srisook, P; Suphakun, P; Tabtimmai, L; Ward, SE1
Gu, HM; Peters, W; Warhurst, DC1
Davis, TM; Johnston, WA; Manning, LS; Skinner, TS1
Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C1
Dong, Y; Huang, KG; Liao, MZ; Liu, DQ; Yang, HL; Yang, PF; Yang, YM; Zhang, CY1
Le Bras, J1
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC1
Bangchang, KN; Chaijaroenkul, W; Mungthin, M; Ward, SA1
D'Alessandro, U; Erhart, A; Karema, C; Mupfasoni, D; Rusanganwa, E; Rwagacondo, C; Tinto, H; Van Marck, E; Van Overmeir, C; Vandoren, W1
Anderson, T; Barends, M; Brockman, A; Jaidee, A; Mayxay, M; Nair, S; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; Sudimack, D; White, NJ1
Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P1
Chaijaroenkul, W; Muhamad, P; Na-Bangchang, K; Pruktal, P1
Stepniewska, K; White, NJ1
Davis, TM; Gomorrai, PS; Griffin, S; Ilett, KF; Karunajeewa, HA; Kotab, K; Lautu, D; Law, I; Lin, E; Mueller, I; Oa, O; Page-Sharp, M; Salman, S; Senn, M; Siba, P; Suano, P; Tarongka, N; Ura, A; Wong, R1
Abiodun, O; Bell, A; Brun, R; Chollet, J; Irungu, BN; Kiboi, DM; Langat, B; Nganga, JK; Nyambati, VC; Nzila, A; Rukunga, GM; Wittlin, S1
Giha, HA1
Awab, GR; Day, NP; Dondorp, AM; Imwong, M; Kaker, F; Lee, SJ; Pukrittayakamee, S; Singhasivanon, P; White, NJ; Woodrow, CJ1
Batty, KT; Ilett, KF; Jago, JD; Moore, BR; Page-Sharp, M; Stoney, JR1
Basco, L; Boyer, J; Ibrahim, H; Nepveu, F; Tahar, R; Thompson, E; Vivas, L1
Ashley, EA; Lindegardh, N; Lwin, KM; Nosten, F; Phyo, AP; Price, RN; Russell, B; Singhasivanon, P; Sriprawat, K; White, NJ1
Davis, TM; Wong, RP1
Anstey, NM; Chalfein, F; Haynes, RK; Kenangalem, E; Marfurt, J; Möhrle, JJ; Piera, KA; Prayoga, P; Price, RN; Sebayang, B; Wabiser, F; Wirjanata, G; Wittlin, S1
Abdur, R; Barrette, A; Bouth, DM; Duong, S; Leang, R; Menard, D; Ringwald, P1
Arzika, I; Fandeur, T; Guillebaud, J; Issaka, M; Maazou, A; Salissou, A; Specht, S; Zamanka, H1
Abdi, AI; Kiara, SM; Mwai, L; Nzila, A; Ochola-Oyier, LI; Okombo, J; Pole, L; Sutherland, CJ1
Burkholder, B; Bustos, MD; Delacollette, C; Wongsrichanalai, C1
Fuehrer, HP; Ganesh, D; Graninger, W; Haque, R; Khan, WA; Noedl, H; Starzengruber, P; Swoboda, P1
Bathurst, I; Chaorattanakawee, S; Ding, XC; Lanteri, CA; Lon, C; Rutvisuttinunt, W; Saunders, DL; Tyner, SD; Yingyuen, K1
Baret, E; Bercion, R; Camara, C; Diatta, B; Diémé, Y; Fall, B; Fall, KB; Fall, M; Mbaye, PS; Nakoulima, A; Pascual, A; Pradines, B; Wade, B; Wurtz, N1
Bla, BK; Djaman, JA; Kipré, RG; N'guessan, JD; Trébissou, J; Yapi, FH; Yavo, W1
Bigira, V; Bloome, J; Byaruhanga, O; Conrad, MD; Cooper, RA; Dorsey, G; Greenhouse, B; Gut, J; Havlir, DV; Kakuru, A; Kamya, MR; Kapisi, J; Kozak, B; LeClair, N; Legac, J; Nakazibwe, C; Nsobya, SL; Okiring, J; Rosenthal, PJ; Tumwebaze, P; Walakira, A1
Buathong, N; Chanarat, N; Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Heng, TK; Jacob, C; Kong, N; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Plowe, C; Prom, S; Saingam, P; Saunders, DL; Se, Y; Sea, D; Sriwichai, S; Sundrakes, S; Takala-Harrison, S; Tangthongchaiwiriya, K; Teja-Isavadharm, P; Tyner, SD; Yingyuen, K; Yom, Y1
Chua, HH; Cobbold, SA; Creek, DJ; McConville, MJ; Nijagal, B; Ralph, SA1
Anh, ND; Ca, NTN; Dolecek, C; Dong, LT; Farrar, J; Hien, TT; Hoa, NT; Khanh, TTN; Loi, MA; Nhan, HT; Nhien, NTT; Phu, NH; Son, DH; Thai, CQ; Thai, LH; Thanh, NV; Thuan, PD; Thwaites, G; Van Toi, P; White, NJ; Wolbers, M1
Groger, M; Lötsch, F; Ramharter, M; Rehman, K; Sauerzopf, U; Veletzky, L1
Eastman, RT; Huang, R; Khine, P; Su, XZ; Thomas, CJ1
Amalvict, R; Benoit, N; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA1
Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd1
Biagini, GA; Horrocks, P; Sharma, R; Ullah, I1
Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ1
Khositnithikul, R; Mungthin, M; Sitthichot, N; Suwandittakul, N; Ward, SA; Watanatanasup, E1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA1
Affara, M; Bei, AK; Deme, AB; Dieye, B; Diongue, K; Gaye, A; Koita, O; Krogstad, DJ; Mbaye, A; Ndiaye, D; Ndiaye, IM; Ndiaye, T; Ndiaye, YD; Nwakanma, D; Sy, M; Sy, N; Volkman, S; Yade, MS1
Achieng, AO; Ghosh, PC; Kempaiah, P; Kumar, P; Perkins, DJ; Rajendran, V; Rathi, B; Rawat, M; Singh, BK1
Byaruhanga, O; Ceja, FG; Conrad, MD; Cooper, RA; Katairo, T; Nsobya, SL; Rasmussen, SA; Rosenthal, PJ; Tumwebaze, PK1
Affara, M; Ahmad, A; Amambua-Ngwa, A; Ceesay, S; D'Alessandro, U; El-Fatouri, F; Janha, R; Joof, F; Kolly, O; Mbye, H; Nwakanma, D; Nyang, H; Okebe, J1
Bai, Y; Cao, Y; Cui, L; Deng, S; Geng, J; Li, C; Li, N; Liu, H; Ngassa Mbenda, HG; Ruan, Y; Wang, Z; Wu, Y; Xu, S; Yang, Z; Zeng, W; Zhang, J1
Bin, S; Kim, S; Lek, D; Menard, D; Piv, EP; Popovici, J; Primault, L; Samreth, R; Serre, D; Vantaux, A1
Cen, YZ; Deng, ZH; Li, XH; Liao, YB; Lin, RX; Liu, MR; Pan, B; Pei, FQ; Ren, WF; Ruan, CW1
Goggins, E; Heller, LE; Roepe, PD1
Bancone, G; Carrara, VI; Chu, CS; Imwong, M; Jeeyapant, A; Lee, SJ; Nosten, F; Paw, MK; Phyo, AP; Poe, NP; Proux, S; Raksapraidee, R; Sriprawat, K; Tarning, J; Thinraow, S; Turner, C; Watson, J; White, NJ; Wiladphaingern, J; Wilairisak, P; Win, HH; Yotyingaphiram, W1
Agarwal, D; Awasthi, SK; Gupta, RD; Singh, S1
Bah, S; Dabitao, D; Dama, S; Diakité, M; Diakité, SAS; Doumbia, S; Doumbouya, M; Guindo, MA; Keita, B; Konaté, DS; Sangaré, M; Sanogo, I; Traoré, K1
Coghi, P; Gianoncelli, A; Mastinu, A; Memo, M; Ng, JPL; Ribaudo, G; Wong, VKW; Yang, LJ1
Kasai, S; Kawamura, K; Kume, A; Suzuki, H; Umemiya-Shirafuji, R1
Deni, I; Dhingra, SK; Eppstein, MJ; Fidock, DA; Gil-Iturbe, E; Hagenah, LM; Kim, J; Mancia, F; Mehta, M; Quick, M; Roepe, PD; Small-Saunders, JL; Vendome, J; Wicht, KJ1
Ye, R; Zhang, D; Zhang, Y1
Albert, I; Bath, J; Fidock, DA; Koo, I; Llinás, M; Mok, S; Okombo, J; Orchard, LM; Owens, E; Qahash, T; Yeo, T1
Ballo, FI; Barre, YN; Cisse, F; Coulibaly, M; Dama, S; Dao, F; Daou, A; Dara, A; Dara, JN; Dembele, L; Diakite, O; Diallo, N; Djimde, AA; Doumbia, D; Fofana, B; Goita, S; Haidara, AS; Kone, AK; Koumare, S; Niangaly, AB; Ouattara, A; Ouologuem, DT; Sacko, A; Sangare, CPO; Sissoko, S; Sogore, F; Sylla, D; Tandina, F; Tekete, MM; Traore, A1
Abera, A; Alemayehu, BH; Anand, A; Assefa, A; Bekele, W; Dilu, D; Etana, K; Ezema, B; Girma, S; Haile, M; Hwang, J; Minta, AA; Mohammed, H; Moriarty, LF; Murphy, M; Sime, H; Solomon, H; Svigel, SS; Tadesse, M; Tadesse, Y; Tasew, G; Teka, H; Woyessa, A; Zhou, Z1
Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M1

Reviews

7 review(s) available for chloroquine and artenimol

ArticleYear
Tackling Fungal Resistance by Biofilm Inhibitors.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries

2017
Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Neoplasms; Protein Kinase Inhibitors; Quinazolines

2019
Recent advances in malaria drug discovery.
    Bioorganic & medicinal chemistry letters, 2013, May-15, Volume: 23, Issue:10

    Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure

2013
Approaches to protozoan drug discovery: phenotypic screening.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2013
Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope.
    Parasitology research, 2010, Volume: 106, Issue:3

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sudan; Sulfadoxine; Treatment Failure

2010
Monitoring antimalarial drug efficacy in the Greater Mekong Subregion: an overview of in vivo results from 2008 to 2010.
    The Southeast Asian journal of tropical medicine and public health, 2013, Volume: 44 Suppl 1

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Directly Observed Therapy; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Parasitemia; Quinolines

2013
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
    Parasitology research, 2017, Volume: 116, Issue:2

    Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine

2017

Trials

11 trial(s) available for chloroquine and artenimol

ArticleYear
In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Antimalarials; Child; Child, Preschool; Cohort Studies; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Treatment Outcome; Uganda

2010
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome

2008
A trial of combination antimalarial therapies in children from Papua New Guinea.
    The New England journal of medicine, 2008, Dec-11, Volume: 359, Issue:24

    Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kaplan-Meier Estimate; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Proportional Hazards Models; Pyrimethamine; Quinolines; Recurrence; Sulfadoxine

2008
Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial.
    Malaria journal, 2010, Apr-21, Volume: 9

    Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Vivax; Male; Multivariate Analysis; Plasmodium vivax; Prospective Studies; Quinolines; Recurrence; Treatment Outcome

2010
Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011, Volume: 53, Issue:10

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Female; Humans; Infant; Malaria, Vivax; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium vivax; Quinolines; Recurrence; Risk Factors; Treatment Outcome; Young Adult

2011
A Randomized Comparison of Chloroquine Versus Dihydroartemisinin-Piperaquine for the Treatment of Plasmodium vivax Infection in Vietnam.
    The American journal of tropical medicine and hygiene, 2016, Volume: 94, Issue:4

    Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Male; Plasmodium vivax; Quinolines; Treatment Outcome; Vietnam; Young Adult

2016
Changing Antimalarial Drug Sensitivities in Uganda.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Aspartic Acid Endopeptidases; Child; Child, Preschool; Chloroquine; Drug Resistance; Ethanolamines; Female; Fluorenes; Gene Expression; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinolines; Uganda; Young Adult

2017
Therapeutic and Transmission-Blocking 
Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia.
    Emerging infectious diseases, 2018, Volume: 24, Issue:8

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Quinolines; Young Adult

2018
Chloroquine Versus Dihydroartemisinin-Piperaquine With Standard High-dose Primaquine Given Either for 7 Days or 14 Days in Plasmodium vivax Malaria.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 04-08, Volume: 68, Issue:8

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Middle Aged; Myanmar; Primaquine; Quinolines; Recurrence; Thailand; Young Adult

2019
Therapeutic efficacies of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum and chloroquine and dihydroartemisinin-piperaquine for uncomplicated Plasmodium vivax infection in Ethiopia.
    Malaria journal, 2022, Dec-01, Volume: 21, Issue:1

    Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Ethiopia; Humans; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax

2022
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study.
    The Lancet. Infectious diseases, 2023, Volume: 23, Issue:10

    Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines

2023

Other Studies

101 other study(ies) available for chloroquine and artenimol

ArticleYear
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hemin; Hepatocytes; Humans; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Parasite Load; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes

2016
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.
    Journal of natural products, 2015, Dec-24, Volume: 78, Issue:12

    Topics: Antimalarials; Chalcones; Chloroquine; Crystallography, X-Ray; Flavanones; Flavonoids; HEK293 Cells; Humans; Millettia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Plasmodium falciparum

2015
ICI 56,780 Optimization: Structure-Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity.
    Journal of medicinal chemistry, 2016, 07-28, Volume: 59, Issue:14

    Topics: Animals; Antimalarials; Dose-Response Relationship, Drug; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium berghei; Quinolones; Structure-Activity Relationship

2016
Synthesis and biological evaluation of a series of non-hemiacetal ester derivatives of artemisinin.
    European journal of medicinal chemistry, 2016, Oct-21, Volume: 122

    Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Chemistry Techniques, Synthetic; CHO Cells; Cricetinae; Cricetulus; Drug Design; Esters; Humans; Plasmodium falciparum

2016
Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Animals; Antimalarials; Female; Ferrous Compounds; Heterocyclic Compounds, 1-Ring; Malaria; Mice; Peroxides; Plasmodium berghei; Plasmodium falciparum; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2017
Design and Synthesis of Orally Bioavailable Piperazine Substituted 4(1H)-Quinolones with Potent Antimalarial Activity: Structure-Activity and Structure-Property Relationship Studies.
    Journal of medicinal chemistry, 2018, 02-22, Volume: 61, Issue:4

    Topics: Animals; Antimalarials; Drug Design; Humans; Mice; Piperazine; Plasmodium falciparum; Quinolones; Solubility; Structure-Activity Relationship

2018
Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana.
    Journal of natural products, 2017, 12-22, Volume: 80, Issue:12

    Topics: Antimalarials; Australia; Biological Products; Indole Alkaloids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Plasmodium falciparum; Rutaceae; Trees

2017
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Animals; Anisoles; Antimalarials; Antineoplastic Agents; Antiviral Agents; Artemisinins; Benzofurans; Benzoquinones; Biological Products; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Cytomegalovirus; Humans; Molecular Conformation; Plasmodium falciparum

2018
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship

2019
3,3'-Disubstituted 5,5'-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity.
    Journal of medicinal chemistry, 2019, 03-14, Volume: 62, Issue:5

    Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Plasmodium; Species Specificity; Structure-Activity Relationship; Triazines

2019
Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens.
    Journal of natural products, 2019, 04-26, Volume: 82, Issue:4

    Topics: Oxidation-Reduction; Plant Roots; Rutaceae; Xanthenes

2019
A Meroisoprenoid, Heptenolides, and
    Journal of natural products, 2020, 02-28, Volume: 83, Issue:2

    Topics: Annonaceae; Antimalarials; Flavanones; Flavonoids; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum

2020
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
    Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11

    Topics: Acridones; Administration, Oral; Animals; Antimalarials; Cell Survival; Disease Models, Animal; Female; Half-Life; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Male; Mice; Mice, Inbred C57BL; Plasmodium falciparum; Structure-Activity Relationship

2020
Synthesis, Structure-Activity Relationship, and Antimalarial Efficacy of 6-Chloro-2-arylvinylquinolines.
    Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

    Topics: Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2020
Discovery of fast-acting dual-stage antimalarial agents by profiling pyridylvinylquinoline chemical space via copper catalyzed azide-alkyne cycloadditions.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Antimalarials; Azides; Copper; Cycloaddition Reaction; Hep G2 Cells; Humans; Life Cycle Stages; Malaria, Falciparum; Plasmodium falciparum; Quinolines

2021
Antiplasmodial Alkaloids from the Australian Bryozoan
    Journal of natural products, 2020, 11-25, Volume: 83, Issue:11

    Topics: Animals; Antimalarials; Australia; HEK293 Cells; Humans; Plasmodium falciparum; Spectrum Analysis

2020
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1
    Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10

    Topics: Administration, Oral; Animals; Antimalarials; Cyclization; Disease Models, Animal; Ethers; Female; Half-Life; Hydrogen-Ion Concentration; Malaria; Mice; Mice, Inbred BALB C; Plasmodium falciparum; Prodrugs; Quinolones; Solubility; Structure-Activity Relationship

2021
Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2021
Enantioselective Synthesis and Profiling of Potent, Nonlinear Analogues of Antimalarial Tetraoxanes E209 and N205.
    ACS medicinal chemistry letters, 2021, Jul-08, Volume: 12, Issue:7

    Topics:

2021
Antimicrobial and Cytotoxic Angucyclic Quinones from
    Journal of natural products, 2021, 11-26, Volume: 84, Issue:11

    Topics: Actinomadura; Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Mycobacterium tuberculosis; Plasmodium falciparum; Quinolones

2021
Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 2. Stereospecificity of the ether side chain.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Artemisinins; Chemical Phenomena; Chemistry; Malaria; Mice; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Solubility; Stereoisomerism; Structure-Activity Relationship; Water

1989
Arteether, a new antimalarial drug: synthesis and antimalarial properties.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:3

    Topics: Animals; Antimalarials; Artemisinins; Magnetic Resonance Spectroscopy; Malaria; Mice; Models, Molecular; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes

1988
Structure-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria.
    Journal of medicinal chemistry, 2003, Sep-25, Volume: 46, Issue:20

    Topics: Animals; Antimalarials; Antiprotozoal Agents; Artemisinins; Clone Cells; Drug Design; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Leishmania donovani; Malaria, Falciparum; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Sesquiterpenes; Static Electricity; Stereoisomerism; Structure-Activity Relationship

2003
Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.
    Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

    Topics: Adamantane; Animals; Antimalarials; Cell Line, Tumor; Drug Resistance; Half-Life; Malaria; Malaria, Falciparum; Mice; Micronucleus Tests; Ozone; Peroxides; Plasmodium berghei; Rats; Spiro Compounds; Structure-Activity Relationship

2005
In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Azithromycin; Clinical Trials, Phase II as Topic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes

2007
Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Antagonism; Drug Combinations; Drug Interactions; Drug Resistance; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes; Tritium

2007
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008
Role of known molecular markers of resistance in the antimalarial potency of piperaquine and dihydroartemisinin in vitro.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Quinolines

2009
Atorvastatin is a promising partner for antimalarial drugs in treatment of Plasmodium falciparum malaria.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Animals; Antimalarials; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Plasmodium falciparum; Pyrroles

2009
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil

2009
Antimalarial activity of tigecycline, a novel glycylcycline antibiotic.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Doxycycline; Inhibitory Concentration 50; Minocycline; Parasitic Sensitivity Tests; Plasmodium falciparum; Tetracycline; Tetracyclines; Tigecycline

2009
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:11

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Haplotypes; Madagascar; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase

2009
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Animals; Antimalarials; Artemisinins; Ethanolamines; Fluorenes; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinolines

2009
Antiprotozoal, anticancer and antimicrobial activities of dihydroartemisinin acetal dimers and monomers.
    Bioorganic & medicinal chemistry, 2009, Dec-01, Volume: 17, Issue:23

    Topics: Acetals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Artemisinins; Cell Line, Tumor; Cryptococcus neoformans; Dimerization; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization

2009
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).
    Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1

    Topics: Animals; Antimalarials; Heterocyclic Compounds, 1-Ring; Malaria, Falciparum; Mice; Molecular Conformation; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2010
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Heterocyclic Compounds; Mice; Plasmodium falciparum; Rats

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Amino Acid Sequence; Animals; Antimalarials; Drug Resistance; Humans; Kenya; Mefloquine; Membrane Transport Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Sequence Analysis, DNA; Sodium-Hydrogen Exchangers

2010
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum

2010
Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Antimalarials; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines

2010
Artemisinin-quinoline hybrid-dimers: synthesis and in vitro antiplasmodial activity.
    Bioorganic & medicinal chemistry letters, 2010, Dec-01, Volume: 20, Issue:23

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dimerization; Drug Resistance; Plasmodium falciparum; Quinolines

2010
Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.
    Bioorganic & medicinal chemistry letters, 2011, Mar-15, Volume: 21, Issue:6

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Cell Survival; In Vitro Techniques; Plasmodium falciparum

2011
Antiplasmodial and antitumor activity of dihydroartemisinin analogs derived via the aza-Michael addition reaction.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Aza Compounds; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Molecular Structure; Plasmodium falciparum

2011
Optimization of 1,2,3,4-tetrahydroacridin-9(10H)-ones as antimalarials utilizing structure-activity and structure-property relationships.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Acridines; Animals; Antimalarials; Cell Line; Drug Resistance; Erythrocytes; Humans; In Vitro Techniques; Mice; Microsomes, Liver; Plasmodium falciparum; Solubility; Structure-Activity Relationship

2011
Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones.
    Journal of medicinal chemistry, 2011, Dec-22, Volume: 54, Issue:24

    Topics: Animals; Antimalarials; Atovaquone; Cell Line; Drug Resistance; Mice; Plasmodium falciparum; Quinolones; Structure-Activity Relationship

2011
Synthesis, antimalarial activity and cytotoxicity of 10-aminoethylether derivatives of artemisinin.
    Bioorganic & medicinal chemistry, 2012, Aug-01, Volume: 20, Issue:15

    Topics: Animals; Antimalarials; Artemisinins; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2012
Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy.
    Bioorganic & medicinal chemistry, 2012, Sep-01, Volume: 20, Issue:17

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Antimalarials; Dose-Response Relationship, Drug; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV-1; Humans; Malaria; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2012
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Antimalarials; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Dimerization; Humans; Malaria, Falciparum; Neoplasms; Plasmodium falciparum; Tetraoxanes

2013
Design, Synthesis, and Antiplasmodial Activity of Hybrid Compounds Based on (2R,3S)-N-Benzoyl-3-phenylisoserine.
    ACS medicinal chemistry letters, 2013, Jul-11, Volume: 4, Issue:7

    Topics:

2013
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.
    Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21

    Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship

2014
Synthesis and in vitro biological evaluation of dihydroartemisinyl-chalcone esters.
    European journal of medicinal chemistry, 2015, Jan-27, Volume: 90

    Topics: Antimalarials; Antineoplastic Agents; Artemisinins; Cell Line, Tumor; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Humans; MCF-7 Cells; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship

2015
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Malaria; Mice; Parasites; Plasmodium falciparum; Protein Isoforms

2015
Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Antimalarials; Antineoplastic Agents, Phytogenic; Antiviral Agents; Artemisinins; Humans; Molecular Structure

2015
Evaluation of the anti-malarial activity and cytotoxicity of 2,4-diamino-pyrimidine-based kinase inhibitors.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Animals; Antimalarials; Cell Line, Tumor; Chlorocebus aethiops; Drug Design; Humans; Molecular Docking Simulation; Plasmodium falciparum; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases; Protozoan Proteins; Pyrimidines; Vero Cells

2016
Uptake of [3H] dihydroartemisinine by erythrocytes infected with Plasmodium falciparum in vitro.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984, Volume: 78, Issue:2

    Topics: Anisomycin; Antimalarials; Artemether; Artemisinins; Chloroquine; Erythrocytes; Humans; Plasmodium falciparum; Pyrans; Sesquiterpenes

1984
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs.
    International journal for parasitology, 1996, Volume: 26, Issue:5

    Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes

1996
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials.
    Acta tropica, 1997, Volume: 63, Issue:2-3

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam

1997
In vitro sensitivity of Plasmodium falciparum to eight antimalarials in China-Myanmar and China-Lao PDR border areas.
    The Southeast Asian journal of tropical medicine and public health, 1997, Volume: 28, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; China; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; Laos; Microbial Sensitivity Tests; Myanmar; Naphthyridines; Plasmodium falciparum; Quinine; Sesquiterpenes

1997
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu.
    Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl

    Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel

1998
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study.
    Parasitology, 1999, Volume: 119 ( Pt 5)

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes

1999
In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.
    Malaria journal, 2005, Aug-02, Volume: 4

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Thailand; Time Factors

2005
In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance, Multiple; Female; Humans; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Rwanda; Sesquiterpenes

2006
In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).
    The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:2

    Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Ethanolamines; Female; Fluorenes; Humans; Inhibitory Concentration 50; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Sesquiterpenes

2007
Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycin.
    The Southeast Asian journal of tropical medicine and public health, 2007, Volume: 38, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Fosfomycin; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Schizonts; Sesquiterpenes

2007
Pharmacokinetic determinants of the window of selection for antimalarial drug resistance.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Algorithms; Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance; Malaria; Mefloquine; Models, Theoretical; Pyrimethamine; Quinine

2008
Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
    Experimental parasitology, 2009, Volume: 122, Issue:3

    Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Resistance; Ethanolamines; Female; Fluorenes; Lumefantrine; Malaria; Male; Mice; Parasitemia; Plasmodium berghei; Quinolines; Serial Passage

2009
Pharmacokinetics, pharmacodynamics, and allometric scaling of chloroquine in a murine malaria model.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Malaria; Male; Mice; Mice, Inbred BALB C; Parasitemia; Plasmodium berghei

2011
Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:11

    Topics: Adult; Antimalarials; Artemisinins; Cameroon; Chloroquine; Drug Interactions; Drug Resistance; Female; Humans; Hypoxanthine; Indoles; Malaria, Falciparum; Male; Nitrogen Oxides; Oxidation-Reduction; Parasitic Sensitivity Tests; Plasmodium falciparum

2011
In vitro antimalarial activity and drug interactions of fenofibric acid.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Antimalarials; Artemisinins; Chloroquine; Drug Interactions; Fenofibrate; Humans; Plasmodium falciparum

2012
Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:10

    Topics: Adamantane; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Multiple; Heterocyclic Compounds, 1-Ring; Microbial Sensitivity Tests; Peroxides; Plasmodium falciparum; Plasmodium vivax; Quinolines; Spiro Compounds

2012
Efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Antimalarials; Artemisinins; Cambodia; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Quinolines; Treatment Outcome; Young Adult

2013
Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines; Niger; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines

2013
Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Amino Acid Motifs; Antimalarials; Artemisinins; Asparagine; Aspartic Acid; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Genome, Protozoan; Lumefantrine; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine

2013
Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates.
    Malaria journal, 2014, Jun-10, Volume: 13

    Topics: Adolescent; Adult; Aged; Aminoquinolines; Antimalarials; Artemisinins; Child; Chloroquine; Clindamycin; Drug Interactions; Female; Humans; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Young Adult

2014
Ex vivo activity of endoperoxide antimalarials, including artemisone and arterolane, against multidrug-resistant Plasmodium falciparum isolates from Cambodia.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10

    Topics: Antimalarials; Artemisinins; Artesunate; Cambodia; Chloroquine; Heterocyclic Compounds, 1-Ring; Parasitic Sensitivity Tests; Peroxides; Plasmodium falciparum; Spiro Compounds

2014
Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Biological Transport; Child; Chloroquine; Drug Resistance; Erythrocytes; Ethanolamines; Female; Fluorenes; Gene Expression; Haplotypes; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinine; Senegal

2014
Polymorphisms of the Pfatpase 6 and Pfcrt gene and their relationship with the in vitro susceptibility to dihydroartemisinin and chloroquine of Plasmodium falciparum isolates from Abobo, Côte d'Ivoire.
    Annals of parasitology, 2014, Volume: 60, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Cote d'Ivoire; Drug Resistance; Gene Expression Regulation; Humans; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2014
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Clinical Trials as Topic; Ethanolamines; Fluorenes; Humans; Infant; Lumefantrine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Quinine; Quinolines; Uganda

2015
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult

2015
Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.
    The Journal of infectious diseases, 2016, Jan-15, Volume: 213, Issue:2

    Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Fosfomycin; Gas Chromatography-Mass Spectrometry; Hemoglobins; Inhibitory Concentration 50; Methylene Blue; Naphthyridines; Plasmodium falciparum; Proguanil; Triazines

2016
Effect of mild medical hypothermia on in vitro growth of Plasmodium falciparum and the activity of anti-malarial drugs.
    Malaria journal, 2016, Mar-15, Volume: 15

    Topics: Antimalarials; Artemisinins; Chloroquine; Cold Temperature; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum

2016
PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers.
    Scientific reports, 2016, 05-05, Volume: 6

    Topics: Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Drug Resistance; Drug Therapy, Combination; Gene Expression Regulation; Genotype; Lidocaine; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Sodium Channel Blockers

2016
Absence of Association between Polymorphisms in the RING E3 Ubiquitin Protein Ligase Gene and Ex Vivo Susceptibility to Conventional Antimalarial Drugs in Plasmodium falciparum Isolates from Dakar, Senegal.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Lumefantrine; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Quinine; Quinolines; Senegal; Ubiquitin-Protein Ligases

2016
Highly active ozonides selected against drug resistant malaria.
    Memorias do Instituto Oswaldo Cruz, 2016, Jun-07, Volume: 0

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum

2016
A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials.
    The Journal of antimicrobial chemotherapy, 2017, 03-01, Volume: 72, Issue:3

    Topics: Antimalarials; Artemisinins; Chloroquine; Drug Discovery; Erythrocytes; Inhibitory Concentration 50; Life Cycle Stages; Luminescent Measurements; Parasitic Sensitivity Tests; Plasmodium falciparum

2017
Influence of the
    The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:3

    Topics: Alleles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gene Dosage; Genotyping Techniques; Inhibitory Concentration 50; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Thailand

2017
Association between Polymorphisms in the Pf
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal

2017
Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal.
    Malaria journal, 2017, 06-14, Volume: 16, Issue:1

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genotype; Genotyping Techniques; Humans; Indoles; Inhibitory Concentration 50; Malaria; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Quinolines; Senegal; Young Adult

2017
Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model.
    Scientific reports, 2017, 07-27, Volume: 7, Issue:1

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Female; Humans; Inhibitory Concentration 50; Life Cycle Stages; Malaria; Mice; Phthalimides; Plasmodium berghei; Plasmodium falciparum

2017
Sustained
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12

    Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Fluorenes; Gambia; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines

2017
Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites.
    International journal for parasitology. Drugs and drug resistance, 2018, Volume: 8, Issue:2

    Topics: Antimalarials; Artemisinins; China; Chloroquine; Drug Resistance, Multiple; Epidemiological Monitoring; Genotype; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Mutation; Myanmar; Plasmodium falciparum; Protozoan Proteins

2018
[Diagnosis and Treatment of the First Imported Case of Plasmodium knowlesi Infection in China].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2016, Volume: 34, Issue:6

    Topics: Animals; Antimalarials; Artemisinins; China; Chloroquine; Erythrocytes; Hemeproteins; Humans; Malaria; Microscopy; Plasmodium knowlesi; Polymerase Chain Reaction; Primaquine; Quinolines; Trophozoites

2016
Dihydroartemisinin-Ferriprotoporphyrin IX Adduct Abundance in Plasmodium falciparum Malarial Parasites and the Relationship to Emerging Artemisinin Resistance.
    Biochemistry, 2018, 12-26, Volume: 57, Issue:51

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Heme; Hemin; Humans; Malaria, Falciparum; Plasmodium falciparum

2018
In vitro synergistic interaction of potent 4-aminoquinolines in combination with dihydroartemisinin against chloroquine-resistant Plasmodium falciparum.
    Acta tropica, 2019, Volume: 199

    Topics: Aminoquinolines; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum

2019
Ex-vivo Sensitivity of Plasmodium falciparum to Common Anti-malarial Drugs: The Case of Kéniéroba, a Malaria Endemic Village in Mali.
    Drugs in R&D, 2020, Volume: 20, Issue:3

    Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Infant; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mali; Mefloquine; Plasmodium falciparum; Quinine; Quinolines

2020
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD).
    Natural product research, 2022, Volume: 36, Issue:20

    Topics: Angiotensin-Converting Enzyme 2; Antimalarials; Antiviral Agents; Artemisinins; Binding Sites; Chloroquine; COVID-19 Drug Treatment; Humans; Peptidyl-Dipeptidase A; SARS-CoV-2; Spike Glycoprotein, Coronavirus

2022
Effect of α-tocopheryloxy acetic acid, a vitamin E derivative mitocan, on the experimental infection of mice with Plasmodium yoelii.
    Malaria journal, 2021, Jun-24, Volume: 20, Issue:1

    Topics: Administration, Oral; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Therapy, Combination; Injections, Intraperitoneal; Malaria; Mice; Mice, Inbred C57BL; Plasmodium yoelii; Tocopherols

2021
Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.
    PLoS pathogens, 2022, Volume: 18, Issue:2

    Topics: Alleles; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Membrane Transport Proteins; Piperazines; Plasmodium falciparum; Protozoan Proteins; Quinolines

2022
Evaluations of candidate markers of dihydroartemisinin-piperaquine resistance in Plasmodium falciparum isolates from the China-Myanmar, Thailand-Myanmar, and Thailand-Cambodia borders.
    Parasites & vectors, 2022, Apr-12, Volume: 15, Issue:1

    Topics: Antimalarials; Artemisinins; Biomarkers; Cambodia; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Myanmar; Piperazines; Plasmodium falciparum; Protozoan Proteins; Quinolines; Thailand

2022
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages.
    PLoS pathogens, 2022, Volume: 18, Issue:10

    Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Heme; Hemoglobins; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Parasites; Plasmodium falciparum; Protozoan Proteins

2022
A Novel
    Antimicrobial agents and chemotherapy, 2022, 12-20, Volume: 66, Issue:12

    Topics: Antimalarials; Chloroquine; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine

2022