chloroquine and artemisinin

chloroquine has been researched along with artemisinin in 238 studies

Research

Studies (238)

Timeframe	Studies, this research(%)	All Research%
pre-1990	20 (8.40)	18.7374
1990's	22 (9.24)	18.2507
2000's	58 (24.37)	29.6817
2010's	116 (48.74)	24.3611
2020's	22 (9.24)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Albuquerque, IS; Burojević, J; D'Alessandro, S; Djurković-Djaković, O; Konstantinović, J; Machado, M; Pecic, S; Prudêncio, M; Sciotti, RJ; Šolaja, BA; Srbljanović, J; Štajner, T; Taramelli, D; Terzić, N; Tot, M; Verbić, T; Zlatović, M	1
Avery, VM; Duffy, S; Khalaf, AI; Scott, FJ; Suckling, CJ	1
Brun, R; Faist, J; Kaiser, M; Saf, R; Seebacher, W; Weis, R	1
Khan, SI; Ponnan, P; Rawat, DS; Reddy, PL; Tripathi, M	1
Dong, G; Liu, N; Sheng, C; Wang, Y; Wu, S	1
Avery, VM; Baell, JB; Bullen, HE; Cowman, AF; Crabb, BS; Curtis, JM; Di Rago, AE; Duffy, S; Gilson, PR; Hutton, CA; Jarman, KE; Jousset Subroux, H; Lowes, KN; Nguyen, W; Prinz, B; Sleebs, BE; Tan, C	1
Bahuguna, A; Khan, SI; Kumar, D; Maurya, SS; Rawat, DS	1
Faist, J; Hochegger, P; Kaiser, M; Mäser, P; Saf, R; Seebacher, W; Weis, R	2
Mahajan, S; Vijayaraghavan, S	1
Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK	1
Gut, J; Kumar, S; Kumar, V; Raj, R; Rosenthal, PJ; Saini, A	1
Amendola, G; Chouchene, K; Cosconati, S; Ettari, R; Grasso, S; Gut, J; Hellmich, UA; Krauth-Siegel, RL; Previti, S; Rosenthal, PJ; Schirmeister, T; Schmid, I; Ulrich, K; Wagner, A; Wich, PR; Zappalà, M	1
Brun, R; Kaiser, M; Mazzieri, MR; Nieto, MJ; Pagliero, RJ	1
Feng, LS; Gao, C; Hu, YQ; Wu, X; Xu, L; Xu, Z; Zhang, S; Zhao, F	1
Gut, J; Kumar, V; Rani, A; Rosenthal, PJ; Singh, A	1
Akisue, G; Endo, Y; Etoh, T; Fukuyama, Y; Harada, K; Hirano, T; Ishibashi, M; Ishiyama, A; Iwatsuki, M; Kagechika, H; Kasahara, T; Kubo, M; O Mura, S; Ohsaki, A; Otoguro, K	1
Arrizabalaga, G; Fargnoli, L; Khan, SI; Labadie, GR; Panozzo-Zénere, EA; Porta, EOJ; Tekwani, BL	1
Carvalho, P; Cutler, SJ; Dale, OR; Elokely, KM; ElSohly, MA; Galal Osman, A; Gul, W; Husni, AS; Khan, S; Klein, ML; Radwan, M; Ross, SA; Slade, D; Yadav, VK	1
Çapcı Karagöz, A; Efferth, T; Friedrich, O; Gruber, L; Hahn, F; Hampel, F; Kappes, B; Klein, V; Leidenberger, M; Marschall, M; Reiter, C; Seo, EJ; Tsogoeva, SB	1
Equbal, D; Mohanakrishnan, D; Sahal, D; Sharma, N; Sharma, UK; Sinha, AK	1
Dunn, BM; Durvasula, R; Grishina, M; Gupta, N; Kempaiah, P; Kumar Singh, A; Kumar, P; Kumar, Y; Miller, W; Potemkin, V; Rajendran, V; Rathi, B; Singh, A; Singh, BK; Singh, S	1
Alvarez, S; Arnett, SD; Ball, H; Boshoff, HI; Brothers, RC; Couch, RD; Dowd, CS; Edwards, RL; Girma, M; Haymond, A; Johnson, C; Manikkam, M; McKay, KT; Meyers, MJ; Odom John, AR; Osbourn, DM; Wang, X	1
Bahuguna, A; Khan, SI; Kholiya, R; Kumar, D; Maurya, SS; Rawat, DS	1
Danton, O; Hamburger, M; Kaiser, M; Moridi Farimani, M; Nejad Ebrahimi, S; Neuburger, M; Potterat, O; Ramseyer, J; Salehi, P; Tabefam, M	1
Battista, MR; Brun, R; Calvet, CM; Cirilli, R; Costi, R; De Leo, A; De Vita, D; Di Marco, A; Di Santo, R; Faggi, C; Jennings, GK; Kaiser, M; Madia, VN; Mäser, P; Messore, A; Pepe, G; Pescatori, L; Podust, LM; Saccoliti, F; Scipione, L; Summa, V; Tudino, V	1
Aguiar, ACC; de Souza, JO; Fagundez, C; Gamo, FJ; Guido, RVC; Ottilie, S; Peña, S; Sanz, LM; Scarone, L; Sellanes, D; Serra, GL; Stewart, L; Winzeler, EA; Yardley, V	1
Chu, XM; Gong, KK; Liang, LL; Liu, W; Sun, KL; Wang, C; Wang, WL	1
Adah, D; Chen, X; Dai, L; Goldberg, DE; Guan, J; Leng, F; Li, X; Liu, J; Liu, X; Liu, Z; Lu, Y; Ma, H; McNitt, SA; Meyers, MJ; Nasamu, AS; Polino, AJ; Qin, L; Tortorella, MD; Tu, Z; Xu, J; Zhao, S	1
Charman, SA; Grau, GER; Gut, J; Hunt, NH; Juillard, A; Legac, J; Payne, RJ; Rosenthal, PJ; Stoye, A; Tang, AH; White, KL	1
Cheong, SL; Ng, CH; Tibon, NS	1
Adhikari, N; Gaikwad, VR; Govindarajalu, G; Karale, UB; Krishna, EV; Krishna, VS; Misra, S; Rode, HB; Sijwali, PS; Sriram, D	1
Alajlani, M; Bauer, R; Belaj, F; Brantner, A; Dolensky, J; Hochegger, P; Kaiser, M; Kretschmer, N; Mäser, P; Mohsin, NU; Petritsch, M; Saf, R; Schühly, W; Seebacher, W; Weis, R	1
Abramo, C; David da Silva, A; de Almeida Pimentel, G; de Pilla Varotti, F; Glanzmann, N; Gualberto Pereira, HM; Karine da Costa Nunes, I; Marinho, JA; Martins Guimarães, DS; Navarro, M	1
Baum, J; Bridgford, JL; Charman, SA; Churchyard, A; Crespo, B; Deni, I; Fidock, DA; Gahalawat, S; Gamo, FJ; Laleu, B; Lawong, A; Mittal, N; Mok, S; Niederstrasser, H; Okombo, J; Palmer, MJ; Phillips, MA; Posner, B; Ready, JM; Striepen, J; Winzeler, E; Wittlin, S; Yeo, T; Zhou, A	1
Augereau, JM; Benoit-Vical, F; Deraeve, C; Jimenez, T; Mustière, R; Nguyen, M; Ouji, M	1
Akao, Y; Avery, VM; Charman, SA; Chen, G; Chen, X; Chiu, FCK; Cho, N; Crespo, B; Dechering, KJ; Duffy, S; Kamaura, M; Katneni, K; Laleu, B; Lucantoni, L; Ochida, A; Sanz, LM; Shackleford, DM; Sturm, A; Wang, B; White, KL; Wittlin, S	1
Almolhim, H; Bremers, EK; Butler, JH; Butschek, GJ; Carlier, PR; Cassera, MB; Ding, S; Merino, EF; Rizopoulos, Z; Slebodnick, C; Totrov, M	1
Hokari, R; Inahashi, Y; Koomsiri, W; Leetanasaksakul, K; Matsuo, H; Nakashima, T; Shiomi, K; Suga, T; Takahashi, YK; Thamchaipenet, A; Wattana-Amorn, P	1
Trigg, PI	1
Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T	1
Gu, HM; Inselburg, J	1
Castranova, V; Van Dyke, K; Ye, ZG	1
Walter, RD	1
Kirk, RG; Lee, P; Van Dyke, K; Ye, Z	1
Druilhe, P; Gentilini, M; Stahel, E	1
Chen, L; Gu, HM; Li, GD; Li, J; Qian, YL; Waki, S; Zhu, MY	1
Carroll, FI; Kepler, JA; Lee, YW; Morey, MC; Philip, A	1
Du, YL; Jiang, Q; Li, CS	1
Van Dyke, K; Wimmer, M; Ye, ZG	1
Choudhury, DS; Devi, CU; Ghosh, SK; Sharma, VP; Sinha, S	1
Chawira, AN; Peters, W; Warhurst, DC	1
Chawira, AN; Warhurst, DC	1
Peters, W	1
Beale, GH; Thaithong, S	1
Li, GD	1
Fu, XQ; Gao, MX; Li, GQ; Li, ZL; Liu, HP; Ye, ZG	1
Chiodini, PL; Ellis, CJ	1
Gu, HM; Lu, BF; Qu, ZX	1
Howells, RE	1
Cai, XZ	1
Baric, RS; Bright, P; Handy, J; Peel, SA; Yount, B	1
Basco, LK; Le Bras, J	2
Avery, MA; Chandra-ngam, G; Kamchonwongpaisan, S; Yuthavong, Y	1
Holloway, P; Krishna, S; Pasvol, G; ter Kuile, F; White, NJ	1
Alin, MH; Ashton, M; Bjorkman, A; Bwijo, BA; Kihamia, CM; Mtey, GJ; Premji, Z	1
White, NJ	1
Davis, TM; Johnston, WA; Manning, LS; Skinner, TS	1
Bishop, LP; Hawley, SR; Maggs, JL; O'Neill, PM; Park, BK; Storr, RC; Ward, SA	1
Meshnick, SR	1
Heppner, DG; Kawamoto, F; Nguyen, TD; Sookto, P; Trieu, NT; Wimonwattrawatee, T; Wongsrichanalai, C	1
Van Dyke, K; Ye, Z	1
Alin, MH	1
Cumming, JN; Park, SB; Posner, GH; Shapiro, TA; Wang, D	1
Kremsner, PG; Philipps, J; Radloff, PD; Wernsdorfer, W	1
Le Bras, J	1
White, N	1
Akompong, T; Ghori, N; Haldar, K; VanWye, J	1
Benoit-Vical, F; Meunier, B; Robert, A	2
Duraisingh, MT; Jones, P; Pinder, M; Sambou, I; von Seidlein, L; Warhurst, DC	1
Jain, GK; Pandey, VC; Puri, SK; Singh, S; Srivastava, P	1
Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ	1
Bloland, PB; Ettling, M; Meek, S	1
Ikemoto, N; Ishizuka, Y; Kim, HS; Ko, N; Kobayashi, M; Murakami, N; Shibata, Y; Sugimoto, M; Wataya, Y	1
Etchegorry, MG; Galinski, M; Matthys, F; Nosten, F; White, NJ	1
Angerhofer, CK; Cordell, GA; Han, J; Kim, SU; Lee, JG; Min, SS; Park, SH	1
Faiz, MA; Kawamoto, F; Laoboonchai, A; Lin, K; Noedl, H; Pang, LW; Wimonwattrawatee, T; Wongsrichanalai, C	1
Kollaritsch, H; Krudsood, S; Looareesuwan, S; Noedl, H; Viriyavejakul, P; Wernsdorfer, WH; Wiedermann, G; Wilairatana, P	1
Chauhan, VS; Kannan, R; Sahal, D	1
Björkman, A; Gupta, S; Mariga, ST; Thapar, MM; Wernsdorfer, WH	1
Ferreras, A; Herrera, F; Sánchez, E; Triana, L	1
Domínguez, JN	1
de Vries, PJ; Heisterkamp, SH; Kager, PA; Le, HQ; Nguyen, NV; Nguyen, TV; Phan, GT; Tran, BQ	1
Bray, PG; Hastings, IM; Ward, SA	1
Fidock, DA; Sidhu, AB; Verdier-Pinard, D	1
Benoit-Vical, F; Camus, D; Capron, M; Delhaes, L; Meunier, B	1
Attaran, A; Barnes, KI; Curtis, C; d'Alessandro, U; Fanello, CI; Galinski, MR; Kokwaro, G; Looareesuwan, S; Makanga, M; Mutabingwa, TK; Talisuna, A; Trape, JF; Watkins, WM	1
Barman, K; Dev, V; Phookan, S	1
Singhal, T	1
Carucci, DJ; Cooper, RA	1
Brown, ML; Geyer, JA; Terrell, JC; Trotta, RF	1
Egan, J; Hoppe, HC; Meredith, SA; van Schalkwyk, DA; Weber, BW; Wiehart, UI	1
Beg, MA; Khan, MA; Razi, ST; Smego, RA	1
Majori, G	1
Garner, P; Omari, A	1
Basilico, N; Mondani, M; Monti, D; Olliaro, P; Parapini, S; Taramelli, D	1
Alexander, N; Alloueche, A; Drakeley, CJ; Hallett, RL; Jawara, M; Ord, R; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G	1
Adams, B; Elandalloussi, LM; Smith, PJ	1
Bakyaita, N; Banek, K; Dorsey, G; Kamya, MR; Kilian, A; Kironde, F; Nsobya, SL; Reingold, A; Rosenthal, PJ; Slater, M; Staedke, SG; Talisuna, A; Wabwire-Mangen, F; Yeka, A	1
Eriksen, J; Gustafsson, LL; Minzi, OM; Nsimba, SE; Petzold, M; Sanga, AJ; Tomson, G; Warsame, MY	1
Akoachere, M; Becker, K; Buchholz, K; Burhenne, J; Fischer, E; Haefeli, WE; Schirmer, RH	1
Bourée, P	1
Krishna, S; Woodrow, CJ	1
de Radiguès, X; Diallo, KI; Diallo, M; Djimdé, A; Doumbo, O; Guthmann, JP; Maiga, H; Ngwakum, PA; Sacko, M	1
Hi, YC; Huang, F; Tang, LH; Wang, QM	1
Ahmed, ES; Elamin, SB; Elhassan, AH; Elmardi, KA; Malik, EM; Mannan, AA; Mohamed, TA; Mowien, RM	1
Fidock, DA; Valderramos, SG	1
Kollaritsch, H; Kyavar, L; Rojanawatsirivet, C; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH	1
Congpuong, K; Na-Bangchang, K	1
Benoit-Vical, F; Berry, A; Lelièvre, J	1
Noe, D; Sharma, A; Toler, SM	1
Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L	1
Garcia, CR; Gazarini, ML; Markus, RP; Sigolo, CA; Thomas, AP	1
Afonso, A; Carter, R; Cheesman, S; Cravo, P; Creasey, A; Culleton, R; do Rosario, V; Fidock, DA; Hunt, P; Logan, J; McNae, I; Sidhu, AB; Valderramos, SG	1
D'Altilia, JP; Kindermans, JM; Olliaro, P; Vandenbergh, D; Vreeke, E	1
Benoit-Vical, F; Lelièvre, J; Loup, C; Meunier, B	1
Congpuong, K; Rojanawatsirivet, C; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH; Woitsch, B	1
Chanda, P; Hamer, DH; Olumese, P; Simon, JL; Sipilanyambe, N; Snow, RW	1
Dama, S; Djimdé, A; Doumbo, O; Fofana, B; Hubert, V; Kaddouri, H; Kodio, A; Koné, A; Le Bras, J; Maiga, H; Sangaré, CP; Sidibe, B; Tekete, M; Yattara, O	1
Blumberg, L; Frean, J	1
Ekland, EH; Fidock, DA	1
Bhasin, VK; Bhattacharya, A; Mishra, LC	1
Diarra, M; Guissou, IP; Ouédraogo, LT; Somé, IT	1
Priebe, W; Saliba, KJ; van Schalkwyk, DA	1
Andrianjafy, T; Juliano, JJ; Raharimalala, LA; Randriamanantena, A; Randrianarivelojosia, M; Raveloson, A; Robert, V	1
Engl, M; Gluderer, D; Ogwang, M; Ploner, F; Ploner, M; Prugger, C; Wernsdorfer, G; Wernsdorfer, WH	1
Co, EM; Dennull, RA; Johnson, JD; Reinbold, DD; Waters, NC	1
Fu, Y; Kenny, S; Klonis, N; Tilley, L	1
Clardy, J; Daily, JP; Demas, A; Lakshmanan, V; LeRoux, M; Mboup, S; Ndiaye, D; Ndir, O; Patel, V; Wirth, DF	1
Oguonu, T; Okafor, HU; Shu, EN	1
Chevalley, S; Coste, A; Lopez, A; Pipy, B; Valentin, A	1
Angus, BJ; Anstey, NM; Douglas, NM; Nosten, F; Price, RN	1
Van Noorden, R	1
Blair, S; Deharo, E; Pabón, A	1
Adelsberger, JW; Baseler, MW; Imamichi, T; Oguariri, RM	1
Bei, ZC; Cao, WC; Wang, H; Wang, JY	1
Bharti, PK; Chand, G; Dash, AP; Mehra, RK; Sharma, RK; Shukla, MK; Shukla, MM; Singh, MP; Singh, N	1
Adhikari, M; Alifrangis, M; Bygbjerg, IC; Kapel, CM; Ranjitkar, S; Schousboe, ML; Thomsen, TT	1
Atheaya, H; Khan, SI; Kumar, N; Mamgain, R; Rawat, DS	1
Bera, DK; Biswas, A; Das, M; Das, S; Guha, SK; Kundu, PK; Maji, AK; Mullick, S; Ray, K; Roy, D; Saha, P; Sengupta, S	1
Congpuong, K; Sirichaisinthop, J; Treiber, M; Wernsdorfer, G; Wernsdorfer, WH; Wiedermann, U	1
Ensom, MH; Wilby, KJ	1
Kittikool, D; Sibmooh, N; Srihirun, S; Tangnitipong, S; Thaptimthong, T; Udomsangpetch, R; Unchern, S	1
Al-Farsi, HM; Al-Hashami, ZS; Al-Qahtani, A; Al-Sheikh, AA; Babiker, HA; Bin Dajem, SM	1
Benedict, C; Crandall, I; Macmullin, G; Pillai, DR; Shahinas, D	1
Garner, P; Gelband, H; Graves, PM	3
Noedl, H	1
Alecrim, Md; Chaves, FC; Costa, MR; Hidalgo, Ade F; Magalhães, PM; Pohlit, AM; Silva, LF; Vieira, PP	1
Mita, T; Tanabe, K	1
Beeson, JG; Goodman, CD; Langer, C; McFadden, GI; Wilson, DW	1
Das Sutar, SK; Dhangadamajhi, G; Kar, SK; Ranjit, M	1
Chugh, M; Kumar, S; Malhotra, P; Reddy, VS; Siddiqui, WA; Stuart, KD; Sundararaman, V	1
Alcantara, LM; Ayong, LS; Franco, CH; Franzoi, KD; Freitas-Junior, LH; Kim, J; Lee, S; Moraes, CB	1
Fitri, LE; Saragih, A; Zein, U	1
Cooksey, R; Dahlström, S; Fairhurst, RM; Flegg, JA; Guerin, PJ; Johnson, JD; Le Bras, J; Le Nagard, H; Lim, P; Ménard, D; Mentré, F; Murillo, C; Musset, L; Noedl, H; Nosten, F; Nsobya, SL; Pradines, B; Quashie, NB; Sibley, CH; Sinou, V; Sriprawat, K; Woodrow, CJ	1
Ayong, L; Freitas-Junior, LH; Hansen, MA; Kang, M; Kim, H; Lee, S; Moon, S	1
Fabre, PL; Ibrahim, H; Najahi, E; Nepveu, F; Perio, P; Reybier, K; Souard, F; Yen, NT	1
Baruah, I; Dhiman, S; Goswami, D; Rabha, B; Sharma, DK; Singh, L; Veer, V	1
Appel, J; Bouraoui, A; Croft, S; Dellai, A; Nefzi, A	1
Amewu, RK; Guedes, RC; Gut, J; Lopes, F; Miranda, D; Moreira, R; Newton, AS; O'Neill, PM; Oliveira, R; Rosenthal, PJ; Srivastava, A; Ward, SA	1
Jegajeevanram, K; Karunamoorthi, K; Sabesan, S; Vijayalakshmi, J	1
Dondorp, AM; Faiz, MA; Hien, TT; Mokuolu, OA; Pukrittayakamee, S; White, NJ	1
Flegg, JA; Gharbi, M; Guerin, PJ; Hopkins Sibley, C; Metcalf, CJE; Shewchuk, T; Venkatesan, M	1
Bakshi, RP; Nenortas, E; Shapiro, TA; Sullivan, DJ; Tripathi, AK	1
Anvikar, AR; Arora, U; Kumar, N; Mishra, N; Savargaonkar, D; Shah, NK; Shahi, B; Sonal, GS; Valecha, N	1
Kumar, R; Mohanakrishnan, D; Sahal, D; Sharma, N; Sharma, UK; Sinha, AK	1
Bala, N; Betuela, I; Davis, TM; Hetzel, MW; Lavu, EK; Page-Sharp, M; Pulford, J	1
André-Barrès, C; Mallet-Ladeira, S; Maynadier, M; Ruiz, J; Vial, H	1
Amaratunga, C; Anderson, JM; Chuor, CM; Fairhurst, RM; Mao, S; Sreng, S; Suon, S; Tullo, GS	1
Ahmed, MA; Bhattacharyya, DR; Bora, K; Goswami, BK; Mahanta, J; Mohapatra, PK; Prakash, A; Sarma, B; Sarma, DK	1
Barker, GC; Lapkin, AA; Romero-Canelón, I; Suberu, JO; Sullivan, N	1
Dahlstrom, S; Ferreira, PE; Franzén, O; Gil, JP; Lum, JK; Nosten, F; Osório, NS; Veiga, MI	1
Bhattacharya, S; Chakrabarti, G; Choudhury, D; Datta, S; Ganguli, A	1
Dondorp, A; von Seidlein, L	1
Laufer, MK; Takala-Harrison, S	1
Crespo-Lladó, KN; Ferrer-Rodríguez, I; Ortiz, JG; Pastrana-Mena, R; Serrano, AE; Vega-Rodríguez, J	1
Buathong, N; Chanarat, N; Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Heng, TK; Jacob, C; Kong, N; Kuntawunginn, W; Lanteri, CA; Lin, JT; Lon, C; Plowe, C; Prom, S; Saingam, P; Saunders, DL; Se, Y; Sea, D; Sriwichai, S; Sundrakes, S; Takala-Harrison, S; Tangthongchaiwiriya, K; Teja-Isavadharm, P; Tyner, SD; Yingyuen, K; Yom, Y	1
Alonso, D; Altman, S; Ben Mamoun, C; Deitsch, KW; Garg, A; Wesolowski, D	1
DeFelipe, AP; Fontenla, F; Lamas, J; Leiro, JM; Mallo, N; Sueiro, RA	1
Akala, HM; Auschwitz, JM; Cheruiyot, AC; Gaona, HW; Hickman, MR; Johnson, JD; Kamau, E; Lee, PJ; Leed, SE; Murthy, T; Okello, CO; Talwar, M; Yeda, RA	1
Ajaiyeoba, EO; Fadare, AA; Fasinu, PS; Ogbole, OO; Saka, YA	1
Bhardwaj, J; Goyal, M; Prakash, K; Puri, SK; Siddiqui, AJ; Soni, A	1
Boudhar, A; Chia, WN; Dymock, BW; Loh, CY; Ng, XW; Nosten, F; Tan, KS; Tan, ZM	1
Roberts, L	1
Caillet, C; Guerin, PJ; Newton, PN	1
Cabral, L; Cristiano, ML; Lobo, L; Nogueira, F; Sousa, Bd	1
Cassera, MB; Dalal, S; Ding, J; Kingston, DG; Liu, QF; Merino, EF; Wu, Y; Xu, CH; Yuan, T; Yue, JM; Zhou, B	1
Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ	1
Khositnithikul, R; Mungthin, M; Sitthichot, N; Suwandittakul, N; Ward, SA; Watanatanasup, E	1
Bruneton, C; Guévart, E; Robin, S	1
Deakin, J; Idris-Usman, M; Matthews, H; Nirmalan, NJ; Rajab, M	1
Banura, P; Guler, JL; Houpt, E; Huang, F; Jacob, ST; Laufer, MK; Liu, J; Moore, CC; Pholwat, S; Stroup, S	1
Amalvict, R; Bercion, R; Diatta, B; Diawara, S; Fall, B; Gueye, MW; Kounta, MB; Lo, G; Madamet, M; Nakoulima, A; Pradines, B; Wade, KA	1
Adhin, MR; Barnwell, JW; Chenet, SM; Huber, CS; Kelley, J; Lucchi, N; Macedo de Oliveira, A; Okoth, SA; Udhayakumar, V; Vreden, S	1
Chesnokova, O; Oleinikov, AV; Oleinikov, IV; Tcherniuk, SO	1
Alokozai, A; Baktash, SH; Buhler, C; Cundill, B; Hasanzai, A; Laurent, B; Leslie, T; Mayan, I; Mikhail, A; Mohammed, N; Rahimi, HU; Rowland, M; Whitty, CJM; Willey, B; Wood, M	1
Alam, MS; Auburn, S; Hossain, ME; Johora, FT; Khan, WA; Ley, B; Marfurt, J; Nima, MK; Price, RN; Thriemer, K	1
Çavuş, İ; Kaya, T; Nuraydın, A; Özbilgin, A	1
Aniweh, Y; Ansah, F; Awandare, GA; Chirawurah, JD; Duodu, S; Nyarko, PB	1
Alexandre, MAA; Alves de Lima E Silva, JC; Daher, A; Dos Santos, TC; Lacerda, MVG; Lalloo, DG; Maia, I; Marchesini, P; Nascimento, CT; Pereira, D; Ruffato, R; Santelli, AC; Tada, M	1
Bobade, D; Deshpande, P; Deval, M; Khandare, AV; Shastry, P	1
Baska, KS; Dalal, S; Dhingra, SK; Fidock, DA; Garcia, CRS; Klein, MS; Klemba, M; Krishna, S; Lee, AH; Lewis, IA; Llinás, M; Roepe, PD; Rubiano, K; Singh, MK; Siriwardana, A	1
Boncy, J; Existe, AV; Kano, S; Komaki-Yasuda, K; Vincent, JP	1
Jiang, TL; Li, CH; Tang, T	1
Asua, V; Conrad, MD; Dorsey, G; Kamya, MR; Kigozi, SP; Legac, J; Nsobya, SL; Rosenthal, PJ; Vinden, J	1
Cumming, BM; Goldring, JPD	1
Daher, A; Fontes, CJ; Lalloo, DG; Marchesini, P; Silva, JCAL; Stevens, A; Ter Kuile, FO	1
Baird, JK; Cui, L; He, X; Huang, Y; Lu, Y; Pan, M; Pi, L; Qin, P; Qin, Y; Yang, Z; Zeng, W; Zhao, L; Zou, C	1
Fotoran, WL; Irvine, DJ; Kleiber, N; Liebau, E; Miranda, BNM; Müntefering, T; Wunderlich, G	1
Abuaku, B; Anto, F; Aydemir, O; Bailey, J; Ghansah, A; Hathaway, NJ; Marsh, PW; Mensah, BA; Myers-Hansen, JL; Opoku, M	1
Barrett, MP; Hughes, KR; Rennie, MT; Roberts, AB; Simwela, NV; Waters, AP	1
Batovska, DI; Markova, N; Medhi, B; Radotra, BD; Sehgal, R; Sinha, S	1
Fidock, DA; Mok, S; Wicht, KJ	1
Adeniyi, OM; Ajibaye, O; Aremu, OI; Asogwa, N; Babamale, OA; Fakayode, O; Fatoba, IM; Iyiola, OA; Omotesho, OB; Opeyemi, OA; Salawu, KM; Shittu, O	1
Bhattacharyya, MK; Bhattacharyya, S; Bulusu, G; Jha, P; Padhi, S; Roy, A; Suthram, N	1
Anywar, DA; Auma, MA; Balikagala, B; Emoto, S; Fukuda, N; Hashimoto, M; Hirai, M; Horii, T; Ikeda, M; Kataoka, M; Katuro, OT; Kimura, E; Mita, T; Mori, T; Obwoya, PS; Odongo-Aginya, EI; Ogwang, M; Opio, W; Palacpac, NMQ; Sakurai-Yatsushiro, M; Sekihara, M; Tachibana, SI; Yamauchi, M; Yatsushiro, S	1
Coghi, P; Gianoncelli, A; Mastinu, A; Memo, M; Ng, JPL; Ribaudo, G; Wong, VKW; Yang, LJ	1
Bamadio, A; Djimde, AA; Doumbo, OK; Grivoyannis, A; Maiga, H; Plowe, CV; Sagara, I; Sanogo, K; Tolo, Y; Traore, A; Traore, K; Traore, OB; Traore, ZI	1
Andreu, D; Arce, EM; Avalos-Padilla, Y; Biosca, A; Bouzón-Arnáiz, I; Caño-Prades, O; Fernàndez-Busquets, X; Moita, D; Muñoz-Torrero, D; Prudêncio, M; Román-Álamo, L; Valle, J	1
Chaijaroenkul, W; Jalei, AA; Muhamad, P; Na-Bangchang, K	1
Baird, JK; Berni, A; Budiman, W; Cedar, E; Chand, K; Crenna-Darusallam, C; Duparc, S; Ekawati, LL; Elyazar, I; Fernando, D; Fletcher, K; Goyal, N; Green, JA; Instiaty, I; Jones, S; Kleim, JP; Lardo, S; Martin, A; Noviyanti, R; Prasetya, CB; Rolfe, K; Santy, YW; Satyagraha, AW; Sharma, H; Soebandrio, A; Subekti, D; Sutanto, I; Tan, LK; Taylor, M	1
Abidah, HY; Endharti, AT; Fitri, LE; Huwae, JTR; Khotimah, ARH; Pawestri, AR; Winaris, N	1

Reviews

40 review(s) available for chloroquine and artemisinin

Article	Year
Tackling Fungal Resistance by Biofilm Inhibitors. Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6 Topics: Animals; Antifungal Agents; Biofilms; Drug Discovery; Drug Resistance, Fungal; Fungi; Humans; Models, Molecular; Mycoses; Small Molecule Libraries	2017
Quinoline hybrids and their antiplasmodial and antimalarial activities. European journal of medicinal chemistry, 2017, Oct-20, Volume: 139 Topics: Antimalarials; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines	2017
Triazole derivatives and their antiplasmodial and antimalarial activities. European journal of medicinal chemistry, 2019, Mar-15, Volume: 166 Topics: Animals; Antimalarials; Humans; Parasitic Sensitivity Tests; Plasmodium; Triazoles	2019
Current progress in antimalarial pharmacotherapy and multi-target drug discovery. European journal of medicinal chemistry, 2020, Feb-15, Volume: 188 Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines	2020
Sattahipmycin, a Hexacyclic Xanthone Produced by a Marine-Derived Journal of natural products, 2022, 05-27, Volume: 85, Issue:5 Topics: Escherichia coli; Gram-Positive Bacteria; Humans; Multigene Family; Streptomyces; Xanthones	2022
The problem of drug resistance in malaria. Parasitology, 1985, Volume: 90 ( Pt 4) Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine	1985
Advances in chemotherapy. British medical bulletin, 1982, Volume: 38, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Plasmodium falciparum; Primaquine; Sesquiterpenes; Triazines	1982
The treatment of malaria. The New England journal of medicine, 1996, Sep-12, Volume: 335, Issue:11 Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Malaria, Falciparum; Pregnancy; Prognosis; Sesquiterpenes	1996
Is haemozoin a target for antimalarial drugs? Annals of tropical medicine and parasitology, 1996, Volume: 90, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Hemeproteins; Mice; Plasmodium; Sesquiterpenes	1996
Combination therapy for malaria in Africa: hype or hope? Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12 Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand	2000
Chemotherapeutic agents against malaria: what next after chloroquine? Current topics in medicinal chemistry, 2002, Volume: 2, Issue:11 Topics: Animals; Antimalarials; Artemisinins; Biological Factors; Chloroquine; Folic Acid Antagonists; Humans; Malaria; Protease Inhibitors; Quinine; Sesquiterpenes	2002
Chloroquine and artemisinin: six decades of research--what next? IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:7 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Genes, Protozoan; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Sesquiterpenes	2003
WHO, the Global Fund, and medical malpractice in malaria treatment. Lancet (London, England), 2004, Jan-17, Volume: 363, Issue:9404 Topics: Africa; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria; Malaria, Falciparum; Malpractice; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; World Health Organization	2004
Management of severe malaria. Indian journal of pediatrics, 2004, Volume: 71, Issue:1 Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Combined Modality Therapy; Developing Countries; Endemic Diseases; Exchange Transfusion, Whole Blood; Female; Humans; Incidence; India; Infant; Malaria, Falciparum; Male; Quinine; Randomized Controlled Trials as Topic; Risk Assessment; Sesquiterpenes; Severity of Illness Index; Sex Distribution	2004
Proteomic approaches to studying drug targets and resistance in Plasmodium. Current drug targets. Infectious disorders, 2004, Volume: 4, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Computational Biology; Computers; Drug Resistance; Gene Expression Profiling; Genes, Protozoan; Genome, Protozoan; Genomics; Humans; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mass Spectrometry; Plasmodium; Plasmodium falciparum; Plasmodium vivax; Proteomics; Protozoan Proteins; Sesquiterpenes; Software	2004
Emerging drug--resistance and guidelines for treatment of malaria. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2004, Volume: 14, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Pakistan; Phenanthrenes; Plasmodium falciparum; Quinidine; Quinine; Sesquiterpenes; Time Factors	2004
[Combined antimalarial therapy using artemisinin]. Parassitologia, 2004, Volume: 46, Issue:1-2 Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine	2004
Malaria in endemic areas. Clinical evidence, 2003, Issue:9 Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine	2003
Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance. Cellular and molecular life sciences : CMLS, 2006, Volume: 63, Issue:14 Topics: Africa; Amino Alcohols; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Biological Transport; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Gene Amplification; Humans; Malaria, Falciparum; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Models, Biological; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinine; Sesquiterpenes	2006
Transporters involved in resistance to antimalarial drugs. Trends in pharmacological sciences, 2006, Volume: 27, Issue:11 Topics: Animals; Antimalarials; Artemisinins; Calcium-Transporting ATPases; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sodium-Hydrogen Exchangers	2006
Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand. The Tohoku journal of experimental medicine, 2007, Volume: 211, Issue:2 Topics: Age Factors; Animals; Antimalarials; Artemisinins; Asia, Southeastern; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium; Quinine; Sesquiterpenes; Sex Factors; Sulfadoxine	2007
Artemisinin and chloroquine: do mode of action and mechanism of resistance involve the same protagonists? Current opinion in investigational drugs (London, England : 2000), 2007, Volume: 8, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drugs, Investigational; Humans; Malaria, Falciparum; Molecular Structure; Plasmodium falciparum; Sesquiterpenes	2007
Lessons learnt from the six decades of chloroquine use (1945-2005) to control malaria in Madagascar. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2009, Volume: 103, Issue:1 Topics: Adolescent; Animals; Antimalarials; Artemisinins; Child; Chloroquine; Disease Outbreaks; Drug Resistance; Drug Therapy, Combination; Evidence-Based Practice; Health Policy; Humans; Madagascar; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Prevalence; Protozoan Proteins	2009
Artemisinin combination therapy for vivax malaria. The Lancet. Infectious diseases, 2010, Volume: 10, Issue:6 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax	2010
Pharmacokinetics of antimalarials in pregnancy: a systematic review. Clinical pharmacokinetics, 2011, Nov-01, Volume: 50, Issue:11 Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine	2011
Primaquine for reducing Plasmodium falciparum transmission. The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine	2012
The need for new antimalarial drugs less prone to resistance. Current pharmaceutical design, 2013, Volume: 19, Issue:2 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Design; Drug Resistance; Drug Therapy, Combination; Global Health; Humans; Malaria, Falciparum; Plasmodium falciparum	2013
Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance. Japanese journal of infectious diseases, 2012, Volume: 65, Issue:6 Topics: Africa; Antimalarials; Artemisinins; Asia, Southeastern; Biological Evolution; Chloroquine; Drug Combinations; Drug Resistance; Gene Flow; Humans; Plasmodium falciparum; Pyrimethamine; South America; Sulfadoxine	2012
Chemotherapy and drug resistance status of malaria parasite in northeast India. Asian Pacific journal of tropical medicine, 2013, Volume: 6, Issue:7 Topics: Animals; Anopheles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Malaria, Vivax; Plasmodium falciparum; Plasmodium vivax; Quinine	2013
Role of traditional antimalarial plants in the battle against the global malaria burden. Vector borne and zoonotic diseases (Larchmont, N.Y.), 2013, Volume: 13, Issue:8 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Global Health; Humans; Malaria; Medicine, Traditional; Plant Components, Aerial; Plant Roots; Plants, Medicinal; Plasmodium; Quinine	2013
Malaria. Lancet (London, England), 2014, Feb-22, Volume: 383, Issue:9918 Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine	2014
Antimalarial drug policy in India: past, present & future. The Indian journal of medical research, 2014, Volume: 139, Issue:2 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; India; Malaria; Plasmodium falciparum	2014
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission. The Cochrane database of systematic reviews, 2014, Jun-30, Issue:6 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine	2014
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission. The Cochrane database of systematic reviews, 2015, Feb-19, Issue:2 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine	2015
Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance. Expert review of anti-infective therapy, 2015, Volume: 13, Issue:6 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	2015
Antimalarial drug resistance in Africa: key lessons for the future. Annals of the New York Academy of Sciences, 2015, Volume: 1342 Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Forecasting; Humans; Malaria; Pyrimethamine; Sulfadoxine	2015
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis. Parasitology research, 2017, Volume: 116, Issue:2 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine	2017
[Research progress on heme metabolism in intraerythrocytic plasmodium]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:18 Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Erythrocytes; Heme; Hemoglobins; Humans; Plasmodium	2018
Molecular Mechanisms of Drug Resistance in Annual review of microbiology, 2020, 09-08, Volume: 74 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Quinolines	2020
Antimalarial Drug Resistance: A Brief History of Its Spread in Indonesia. Drug design, development and therapy, 2023, Volume: 17 Topics: Antimalarials; Artemisinins; Chloroquine; Humans; Indonesia	2023

Trials

12 trial(s) available for chloroquine and artemisinin

Article	Year
The problem of drug resistance in malaria. Parasitology, 1985, Volume: 90 ( Pt 4) Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine	1985
Efficacy of oral and intravenous artesunate in male Tanzanian adults with Plasmodium falciparum malaria and in vitro susceptibility to artemisinin, chloroquine, and mefloquine. The American journal of tropical medicine and hygiene, 1995, Volume: 53, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drugs, Chinese Herbal; Erythrocytes; Humans; Injections, Intravenous; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Parasitemia; Plasmodium falciparum; Recurrence; Sesquiterpenes; Tanzania	1995
In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance. The American journal of tropical medicine and hygiene, 2001, Volume: 65, Issue:6 Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Models, Biological; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine; Recurrence; Sesquiterpenes	2001
Artemisinin or chloroquine for blood stage Plasmodium vivax malaria in Vietnam. Tropical medicine & international health : TM & IH, 2002, Volume: 7, Issue:10 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Double-Blind Method; Drug Resistance; Female; Humans; Malaria, Vivax; Male; Middle Aged; Parasitemia; Plasmodium vivax; Sesquiterpenes; Treatment Outcome; Vietnam	2002
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. PLoS medicine, 2005, Volume: 2, Issue:7 Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infections; Malaria; Male; Pyrimethamine; Risk Factors; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Uganda	2005
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:11 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure	2006
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar. Malaria journal, 2007, May-22, Volume: 6 Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome	2007
Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance. Journal of tropical pediatrics, 2010, Volume: 56, Issue:6 Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Gametogenesis; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfalene; Treatment Outcome	2010
Efficacy of chloroquine and sulphadoxine-pyrimethamine either alone or in combination before introduction of ACT as first-line therapy in uncomplicated Plasmodium falciparum malaria in Jalpaiguri District, West Bengal, India. Tropical medicine & international health : TM & IH, 2011, Volume: 16, Issue:8 Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; India; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult	2011
Use of malaria rapid diagnostic tests by community health workers in Afghanistan: cluster randomised trial. BMC medicine, 2017, 07-07, Volume: 15, Issue:1 Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Community Health Workers; Diagnostic Tests, Routine; Female; Humans; Infant; Infant, Newborn; Malaria; Malaria, Falciparum; Male; Plasmodium vivax; Trimethoprim, Sulfamethoxazole Drug Combination	2017
Efficacy and safety of artemisinin-based combination therapy and chloroquine with concomitant primaquine to treat Plasmodium vivax malaria in Brazil: an open label randomized clinical trial. Malaria journal, 2018, Jan-24, Volume: 17, Issue:1 Topics: Adult; Aged; Artemisinins; Brazil; Chloroquine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Young Adult	2018
Tafenoquine co-administered with dihydroartemisinin-piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study. The Lancet. Infectious diseases, 2023, Volume: 23, Issue:10 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Quinolines	2023

Other Studies

187 other study(ies) available for chloroquine and artemisinin

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials? Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1 Topics: Aminoquinolines; Animals; Antimalarials; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Hemin; Hepatocytes; Humans; In Vitro Techniques; Liver; Mice; Microsomes, Liver; Parasite Load; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes	2016
Selective anti-malarial minor groove binders. Bioorganic & medicinal chemistry letters, 2016, 07-15, Volume: 26, Issue:14 Topics: Antimalarials; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2016
Antiprotozoal activity of bicycles featuring a dimethylamino group at their bridgehead. Bioorganic & medicinal chemistry, 2016, 08-15, Volume: 24, Issue:16 Topics: Animals; Antiprotozoal Agents; Bridged Bicyclo Compounds; Cells, Cultured; Plasmodium falciparum; Rats; Spectrum Analysis; Structure-Activity Relationship; Trypanosoma brucei rhodesiense	2016
Design, synthesis and evaluation of 4-aminoquinoline-purine hybrids as potential antiplasmodial agents. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Drug Resistance, Fungal; Heme; Humans; Hypoxanthine Phosphoribosyltransferase; Molecular Docking Simulation; Plasmodium falciparum; Purines	2017
Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. Journal of medicinal chemistry, 2017, 02-09, Volume: 60, Issue:3 Topics: Administration, Oral; Animals; Antimalarials; Disease Models, Animal; Mice; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship	2017
Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids. European journal of medicinal chemistry, 2017, Mar-31, Volume: 129 Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Cell Line; Heme; Humans; Molecular Docking Simulation; Multienzyme Complexes; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase	2017
New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity. Bioorganic & medicinal chemistry, 2017, 04-01, Volume: 25, Issue:7 Topics: Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Spectrum Analysis; Structure-Activity Relationship	2017
Docking, synthesis and antimalarial activity of novel 4-anilinoquinoline derivatives. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Aniline Compounds; Antimalarials; Cysteine Endopeptidases; Hemeproteins; Humans; Malaria; Molecular Docking Simulation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Protozoan Proteins; Quinolines; Structure-Activity Relationship	2017
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate. Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13 Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2017
4-Aminoquinoline-chalcone/-N-acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation. European journal of medicinal chemistry, 2017, Sep-29, Volume: 138 Topics: Aminoquinolines; Antimalarials; Chalcone; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Structure-Activity Relationship	2017
Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs). Journal of medicinal chemistry, 2017, 08-24, Volume: 60, Issue:16 Topics: Antimalarials; Carbamates; Cathepsin L; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; HeLa Cells; Humans; Hydrogen Bonding; Malaria; Molecular Docking Simulation; Molecular Dynamics Simulation; Neglected Diseases; Phenylalanine; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2017
Lead selection of antiparasitic compounds from a focused library of benzenesulfonyl derivatives of heterocycles. Bioorganic & medicinal chemistry letters, 2017, 09-01, Volume: 27, Issue:17 Topics: Animals; Antiparasitic Agents; Benzyl Compounds; Dose-Response Relationship, Drug; Heterocyclic Compounds; Leishmania donovani; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2017
Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Aminoquinolines; Antimalarials; Dose-Response Relationship, Drug; Microwaves; Molecular Structure; Parasitic Sensitivity Tests; Phthalimides; Plasmodium falciparum; Structure-Activity Relationship	2018
Sucupiranins A-L, Furanocassane Diterpenoids from the Seeds of Bowdichia virgilioides. Journal of natural products, 2017, 12-22, Volume: 80, Issue:12 Topics: Antimalarials; Crystallography, X-Ray; Diterpenes; Fabaceae; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Nitric Oxide; Plasmodium falciparum; Seeds	2017
A minimalistic approach to develop new anti-apicomplexa polyamines analogs. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Antiparasitic Agents; Apicomplexa; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polyamines; Structure-Activity Relationship; Toxoplasma	2018
Bioactive products from singlet oxygen photooxygenation of cannabinoids. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antiprotozoal Agents; Bacteria; Cannabinoids; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fungi; Humans; Leishmania major; Microbial Sensitivity Tests; Parasitic Sensitivity Tests; Photochemical Processes; Plasmodium falciparum; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Singlet Oxygen	2018
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin. Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12 Topics: Animals; Anisoles; Antimalarials; Antineoplastic Agents; Antiviral Agents; Artemisinins; Benzofurans; Benzoquinones; Biological Products; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Cytomegalovirus; Humans; Molecular Conformation; Plasmodium falciparum	2018
Facile synthesis of vanillin-based novel bischalcones identifies one that induces apoptosis and displays synergy with Artemisinin in killing chloroquine resistant Plasmodium falciparum. European journal of medicinal chemistry, 2018, Jul-15, Volume: 155 Topics: Antimalarials; Apoptosis; Artemisinins; Benzaldehydes; Cell Line, Tumor; Cell Survival; Chalcones; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; HeLa Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2018
Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors. Bioorganic & medicinal chemistry, 2018, 07-30, Volume: 26, Issue:13 Topics: Animals; Antimalarials; Aspartic Acid Endopeptidases; Binding Sites; Cell Survival; Chlorocebus aethiops; Drug Design; Ethylamines; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Plasmodium falciparum; Protein Structure, Tertiary; Structure-Activity Relationship; Vero Cells	2018
MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria. Journal of medicinal chemistry, 2018, 10-11, Volume: 61, Issue:19 Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Female; Fosfomycin; Malaria, Falciparum; Mice; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship	2018
N-Substituted aminoquinoline-pyrimidine hybrids: Synthesis, in vitro antimalarial activity evaluation and docking studies. European journal of medicinal chemistry, 2019, Jan-15, Volume: 162 Topics: Aminoquinolines; Animals; Antimalarials; Chlorocebus aethiops; Heme; Molecular Docking Simulation; Plasmodium falciparum; Pyrimidines; Vero Cells	2019
Antiprotozoal Isoprenoids from Salvia hydrangea. Journal of natural products, 2018, 12-28, Volume: 81, Issue:12 Topics: Animals; Antiprotozoal Agents; Cell Line; Leishmania donovani; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Rats; Salvia; Spectrum Analysis; Terpenes; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2018
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Drug Evaluation, Preclinical; Humans; Imidazoles; Parasitic Sensitivity Tests; Trypanosoma	2019
Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing ACS medicinal chemistry letters, 2019, Jan-10, Volume: 10, Issue:1 Topics:	2019
4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides. Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7 Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Disease Models, Animal; Drug Evaluation, Preclinical; Malaria; Mice; Microsomes, Liver; Pyrrolidines; Structure-Activity Relationship	2019
Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity. Bioorganic & medicinal chemistry, 2019, 05-15, Volume: 27, Issue:10 Topics: Animals; Antimalarials; Cell Line; Cell Survival; Disease Models, Animal; Drug Resistance; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2019
Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials. Journal of medicinal chemistry, 2019, 06-13, Volume: 62, Issue:11 Topics: Animals; Antimalarials; Antimicrobial Cationic Peptides; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Female; Inhibitory Concentration 50; Mice; Plasmodium falciparum	2019
Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens. Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8 Topics: Antimalarials; Antitubercular Agents; Dose-Response Relationship, Drug; Malaria, Falciparum; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrvinium Compounds; Structure-Activity Relationship; Tuberculosis	2020
Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents; Candida albicans; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epidermis; Escherichia coli; Female; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pseudomonas aeruginosa; Quaternary Ammonium Compounds; Rats; Salts; Staphylococcus aureus; Structure-Activity Relationship	2021
In vitro and in vivo antiplasmodial activity of novel quinoline derivative compounds by molecular hybridization. European journal of medicinal chemistry, 2021, Apr-05, Volume: 215 Topics: Animals; Antimalarials; Cell Line; Erythrocytes; Female; Hemeproteins; Hemin; Hemolysis; Humans; Malaria; Mice; Plasmodium falciparum; Quinolines	2021
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5 Topics: Amides; Antimalarials; Drug Resistance, Microbial; Hemeproteins; Hemoglobins; Hep G2 Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship; Tetrazoles	2021
Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites. Bioorganic & medicinal chemistry letters, 2021, 05-01, Volume: 39 Topics: Antimalarials; Artemisinins; Atovaquone; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Triclosan	2021
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials. Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17 Topics: Administration, Oral; Animals; Antimalarials; Humans; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium falciparum; Quinazolinones; Structure-Activity Relationship	2021
Enantiopure Benzofuran-2-carboxamides of 1-Aryltetrahydro-β-carbolines Are Potent Antimalarials ACS medicinal chemistry letters, 2022, Mar-10, Volume: 13, Issue:3 Topics:	2022
Drug use and design in the nineties. Acta Leidensia, 1991, Volume: 60, Issue:1 Topics: Aminoquinolines; Amodiaquine; Antimalarials; Artemisinins; Calcium Channel Blockers; Chloroquine; Humans; Malaria; Mefloquine; Naphthoquinones; Phenanthrenes; Primaquine; Quinine; Sesquiterpenes; Sulfadoxine	1991
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand. The American journal of tropical medicine and hygiene, 1991, Volume: 44, Issue:5 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand	1991
Premature release of Plasmodium falciparum from swollen erythrocytes induced by some antimalarials. The Journal of parasitology, 1989, Volume: 75, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Azure Stains; Cells, Cultured; Chloroquine; Erythrocyte Membrane; Erythrocytes; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes	1989
The potentiating action of tetrandrine in combination with chloroquine or qinghaosu against chloroquine-sensitive and resistant falciparum malaria. Biochemical and biophysical research communications, 1989, Dec-15, Volume: 165, Issue:2 Topics: Alkaloids; Animals; Antimalarials; Artemisinins; Benzylisoquinolines; Chloroquine; Drug Resistance; Drug Synergism; Malaria; Plasmodium falciparum; Sesquiterpenes; Species Specificity	1989
Plasmodium falciparum: inhibition of dolichol kinase by mefloquine. Experimental parasitology, 1986, Volume: 62, Issue:3 Topics: Animals; Artemisinins; Cations, Divalent; Chloroquine; Cytidine Triphosphate; Detergents; Dolichols; Egtazic Acid; Erythrocytes; Hydrogen-Ion Concentration; Kinetics; Mefloquine; Microsomes; Nucleotides; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Plasmodium falciparum; Quinolines; Sesquiterpenes; Trifluoperazine	1986
X-ray microanalysis of Plasmodium falciparum and infected red blood cells: effects of qinghaosu and chloroquine on potassium, sodium, and phosphorus composition. The American journal of tropical medicine and hygiene, 1988, Volume: 39, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Electrolytes; Electron Probe Microanalysis; Erythrocytes; Humans; In Vitro Techniques; Phosphorus; Plasmodium falciparum; Potassium; Sesquiterpenes; Sodium	1988
Antagonism of chloroquine with other antimalarials. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:2 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine	1988
Fluorometric determination of the antimalarial efficacy of artemisinin and artemether against Plasmodium falciparum in vitro. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:2 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Plasmodium falciparum; Sesquiterpenes; Spectrometry, Fluorescence	1988
1,2,4-Trioxanes as potential antimalarial agents. Journal of medicinal chemistry, 1988, Volume: 31, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Sesquiterpenes; Structure-Activity Relationship	1988
[Development of a qinghaosu-resistant line of Plasmodium berghei ANKA and N strain]. Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:11 Topics: Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Plasmodium berghei; Primaquine; Pyrans; Sesquiterpenes	1986
Effect of artemisinin (qinghaosu) and chloroquine on drug-sensitive and drug-resistant strains of Plasmodium falciparum malaria: use of [2,8-3H]adenosine as an alternative to [G-3H]hypoxanthine in the assessment of in vitro antimalarial activity. Experimental parasitology, 1987, Volume: 64, Issue:3 Topics: Adenosine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Malaria; Mice; Plasmodium falciparum; Sesquiterpenes	1987
In vitro chloroquine resistant Plasmodium falciparum in Calcutta and its sensitivity to qinghaosu (artemisitene). Indian journal of malariology, 1987, Volume: 24, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Humans; India; Plasmodium falciparum; Sesquiterpenes	1987
Qinghaosu resistance in rodent malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Malaria; Male; Mice; Plasmodium; Plasmodium berghei; Sesquiterpenes	1986
The effect of artemisinin combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro. The Journal of tropical medicine and hygiene, 1987, Volume: 90, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Plasmodium falciparum; Sesquiterpenes	1987
Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether. Bulletin of the World Health Organization, 1985, Volume: 63, Issue:3 Topics: Animals; Artemether; Artemisinins; Chloroquine; Drug Combinations; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thailand	1985
[Development of a piperaquine-resistant line of Plasmodium berghei K 173 strain]. Yao xue xue bao = Acta pharmaceutica Sinica, 1985, Volume: 20, Issue:6 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Quinolines; Sesquiterpenes	1985
Effects of Qinghaosu and chloroquine on the ultrastructure of the erythrocytic stage of P. falciparum in continuous cultivation in vitro. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 1983, Volume: 3, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Erythrocytes; Microscopy, Electron; Plasmodium falciparum; Sesquiterpenes	1983
The treatment of falciparum malaria. The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:4 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria; Mefloquine; Plasmodium falciparum; Quinidine; Quinine; Quinolines; Sesquiterpenes	1984
[Antimalarial activities of 25 derivatives of artemisinine against chloroquine-resistant plasmodium berghei (author's transl)]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1980, Volume: 1, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Male; Mice; Plasmodium berghei; Pyrans; Sesquiterpenes; Structure-Activity Relationship	1980
[Observation of therapeutic effect of single-dose combined administration of Qinghaosu, sulphomethoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant malignant malaria (author's transl)]. Zhonghua nei ke za zhi, 1981, Volume: 20, Issue:12 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfamethazine	1981
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1994, Volume: 51, Issue:5 Topics: Animals; Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Blotting, Southern; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Gene Amplification; Gene Expression; Genes, Protozoan; Mefloquine; Molecular Sequence Data; Phenanthrenes; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Quinine; RNA, Messenger; Selection, Genetic; Sequence Homology, Nucleic Acid; Sesquiterpenes	1994
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives. Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:2 Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines	1994
Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting alpha-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes. The Journal of clinical investigation, 1994, Volume: 93, Issue:2 Topics: alpha-Thalassemia; Animals; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Drug Resistance; Erythrocytes; Hemoglobin H; Hemoglobins, Abnormal; Humans; Plasmodium falciparum; Reference Values; Sesquiterpenes	1994
In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes	1993
Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria. Experimental parasitology, 1993, Volume: 76, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Cell Differentiation; Chloroquine; Drugs, Chinese Herbal; Hypoxanthine; Hypoxanthines; Lactates; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes	1993
In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs. International journal for parasitology, 1996, Volume: 26, Issue:5 Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Humans; In Vitro Techniques; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Quinine; Sesquiterpenes	1996
Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of benzylamino and alkylamino ether analogues of artemisinin. Journal of medicinal chemistry, 1996, Oct-25, Volume: 39, Issue:22 Topics: Animals; Antimalarials; Artemisinins; Cell Line; Chloroquine; Drugs, Chinese Herbal; Plasmodium falciparum; Sesquiterpenes	1996
In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials. Acta tropica, 1997, Volume: 63, Issue:2-3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Sesquiterpenes; Vietnam	1997
Interaction of artemisinin and tetracycline or erythromycin against Plasmodium falciparum in vitro. Parasite (Paris, France), 1994, Volume: 1, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythromycin; Plasmodium falciparum; Protein Synthesis Inhibitors; Sesquiterpenes; Tetracycline	1994
In vitro susceptibility of Tanzanian wild isolates of Plasmodium falciparum to artemisinin, chloroquine, sulfadoxine/pyrimethamine and mefloquine. Parasitology, 1997, Volume: 114 ( Pt 6) Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Humans; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tanzania	1997
Design, synthesis, derivatization, and structure-activity relationships of simplified, tricyclic, 1,2,4-trioxane alcohol analogues of the antimalarial artemisinin. Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Design; Drug Evaluation, Preclinical; Heterocyclic Compounds; Plasmodium falciparum; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship	1998
Follow-up of the susceptibility of Plasmodium falciparum to antimalarials in Gabon. The American journal of tropical medicine and hygiene, 1998, Volume: 58, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Follow-Up Studies; Gabon; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Quinine; Sesquiterpenes; Sulfadoxine	1998
In vitro susceptibility of African Plasmodium falciparum isolates to dihydroartemisinin and the risk factors for resistance to qinghaosu. Medecine tropicale : revue du Corps de sante colonial, 1998, Volume: 58, Issue:3 Suppl Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Cross Reactions; Drug Evaluation, Preclinical; Drug Resistance; France; Humans; Malaria, Falciparum; Mefloquine; Phenanthrenes; Plasmodium falciparum; Sesquiterpenes; Travel	1998
Antimalarial drug resistance and combination chemotherapy. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1999, Apr-29, Volume: 354, Issue:1384 Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Sesquiterpenes	1999
Artemisinin and its derivatives are transported by a vacuolar-network of Plasmodium falciparum and their anti-malarial activities are additive with toxic sphingolipid analogues that block the network. Molecular and biochemical parasitology, 1999, Jun-25, Volume: 101, Issue:1-2 Topics: Animals; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Fluorescent Antibody Technique, Indirect; Humans; Malaria, Falciparum; Membrane Proteins; Microscopy, Electron; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Sphingolipids; Vacuoles	1999
Potentiation of artemisinin activity against chloroquine-resistant Plasmodium falciparum strains by using heme models. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Humans; Metalloporphyrins; Plasmodium falciparum; Sesquiterpenes	1999
Inoculum effect leads to overestimation of in vitro resistance for artemisinin derivatives and standard antimalarials: a Gambian field study. Parasitology, 1999, Volume: 119 ( Pt 5) Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gambia; Hematocrit; Humans; Malaria, Falciparum; Mefloquine; Parasitemia; Phenanthrenes; Plasmodium falciparum; Quinine; Scintillation Counting; Sensitivity and Specificity; Sesquiterpenes	1999
A simple and rapid evaluation of methemoglobin toxicity of 8-aminoquinolines and related compounds. Ecotoxicology and environmental safety, 2000, Volume: 45, Issue:3 Topics: Administration, Cutaneous; Administration, Oral; Aminoquinolines; Animals; Antimalarials; Artemisinins; Cell-Free System; Chloroquine; Cytochrome-B(5) Reductase; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Erythrocytes; Macaca mulatta; Methemoglobin; Methemoglobinemia; Muridae; Oxyhemoglobins; Primaquine; Rats; Sesquiterpenes	2000
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature, 2000, Feb-24, Volume: 403, Issue:6772 Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil	2000
In vitro and in vivo potentiation of artemisinin and synthetic endoperoxide antimalarial drugs by metalloporphyrins. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:10 Topics: Animals; Antimalarials; Artemisinins; Cell Line; Chloroquine; Drug Resistance; Drug Synergism; Humans; Malaria, Falciparum; Metalloporphyrins; Mice; Peroxides; Plasmodium falciparum; Sesquiterpenes	2000
Potent in vivo antimalarial activity of 3,15-di-O-acetylbruceolide against Plasmodium berghei infection in mice. Parasitology international, 2000, Volume: 48, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Carbolines; Chloroquine; Dose-Response Relationship, Drug; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium berghei; Pyridones; Random Allocation; Sesquiterpenes	2000
Malaria epidemic in Burundi. Lancet (London, England), 2001, Mar-31, Volume: 357, Issue:9261 Topics: Antimalarials; Artemisinins; Burundi; Chloroquine; Disease Outbreaks; Drug Therapy, Combination; Humans; Malaria, Falciparum; Sesquiterpenes	2001
Synthesis of new artemisinin analogues from artemisinic acid modified at C-3 and C-13 and their antimalarial activity. Journal of natural products, 2001, Volume: 64, Issue:9 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Chromatography, Thin Layer; Drug Resistance, Microbial; Drugs, Chinese Herbal; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; KB Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Plasmodium falciparum; Sesquiterpenes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Structure-Activity Relationship	2001
In vitro susceptibility of Plasmodium falciparum isolates from Myanmar to antimalarial drugs. The American journal of tropical medicine and hygiene, 2001, Volume: 65, Issue:5 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes	2001
Heme-artemisinin adducts are crucial mediators of the ability of artemisinin to inhibit heme polymerization. Chemistry & biology, 2002, Volume: 9, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Heme; Plasmodium yoelii; Polymers; Protein Binding; Proteins; Sesquiterpenes	2002
Plasmodium falciparum: in vitro interactions of artemisinin with amodiaquine, pyronaridine, and chloroquine. Experimental parasitology, 2002, Volume: 100, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes	2002
Effect of antimalarial drugs on plasmodia cell-free protein synthesis. Memorias do Instituto Oswaldo Cruz, 2002, Volume: 97, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Electrophoresis, Polyacrylamide Gel; Plasmodium falciparum; Primaquine; Protein Biosynthesis; Protein Synthesis Inhibitors; Protozoan Proteins; RNA, Messenger; Sesquiterpenes	2002
Parasitology. A requiem for chloroquine. Science (New York, N.Y.), 2002, Oct-04, Volume: 298, Issue:5591 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Drug Tolerance; Evolution, Molecular; Genes, Protozoan; Humans; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes; Tetrahydrofolate Dehydrogenase	2002
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science (New York, N.Y.), 2002, Oct-04, Volume: 298, Issue:5591 Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil	2002
Therapeutic efficacies of antimalarial drugs in the treatment of uncomplicated, Plasmodium falciparum malaria in Assam, north-eastern India. Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:8 Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine	2003
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum. Biochemistry, 2004, May-04, Volume: 43, Issue:17 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays	2004
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:7 Topics: Ammonium Chloride; Animals; Antimalarials; Artemisinins; Biotin; Blotting, Western; Chloroquine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Hemoglobins; Mefloquine; Microscopy, Electron; Microscopy, Fluorescence; Monensin; Plasmodium falciparum; Quinolones; Sesquiterpenes; Transport Vesicles; Vacuoles	2004
Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin. FEBS letters, 2004, Sep-24, Volume: 575, Issue:1-3 Topics: Animals; Antimalarials; Artemisinins; Carbon Monoxide; Chloroquine; Erythrocytes; Heme; Hemoglobins; Humans; Iron; Malaria; Oxidation-Reduction; Oxidative Stress; Oxygen; Plasmodium falciparum; Sesquiterpenes	2004
Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10 Topics: Alleles; Animals; Anopheles; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Drug Resistance; Drug Therapy, Combination; Genotype; Humans; Malaria; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Sesquiterpenes	2004
ATPase activity of purified plasma membranes and digestive vacuoles from Plasmodium falciparum. Molecular and biochemical parasitology, 2005, Volume: 141, Issue:1 Topics: Adenosine Triphosphatases; Animals; Antimalarials; Artemisinins; Cell Membrane; Chloroquine; Drug Resistance; Mefloquine; Plasmodium falciparum; Quinine; Sesquiterpenes; Subcellular Fractions; Vacuoles	2005
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community. Tropical medicine & international health : TM & IH, 2005, Volume: 10, Issue:10 Topics: Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria, Falciparum; Male; Patient Acceptance of Health Care; Population Surveillance; Pyrimethamine; Rural Health; Self Administration; Sesquiterpenes; Sulfadoxine; Tanzania	2005
In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:11 Topics: Animals; Artemisinins; Chloroquine; Drug Resistance; Drug Synergism; Erythrocytes; Methylene Blue; Parasitic Sensitivity Tests; Plasmodium falciparum; Sesquiterpenes	2005
[Malaria: a medical and economic problem]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:4 Pt 1 Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Health Care Costs; Humans; Lumefantrine; Malaria, Falciparum; Naphthoquinones; Proguanil; Sesquiterpenes; Survival Rate; World Health Organization	2006
[The microfluorimetric assay (MFA) in in vitro testing the sensitivity of Plasmodium falciparum to antimalarial drugs]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2006, Feb-28, Volume: 24, Issue:1 Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Cytophotometry; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Reproducibility of Results	2006
From chloroquine to artemisinin-based combination therapy: the Sudanese experience. Malaria journal, 2006, Jul-31, Volume: 5 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors	2006
In vitro interaction between artemisinin and chloroquine as well as desbutyl-benflumetol in Plasmodium vivax. Wiener klinische Wochenschrift, 2006, Volume: 118, Issue:19-20 Supp Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Ethanolamines; Fluorenes; Humans; In Vitro Techniques; Parasitic Sensitivity Tests; Plasmodium vivax; Sesquiterpenes; Thailand	2006
Selective enhancement of cellular oxidative stress by chloroquine: implications for the treatment of glioblastoma multiforme. Neurosurgical focus, 2006, Dec-15, Volume: 21, Issue:6 Topics: Animals; Artemisinins; Brain Neoplasms; Chloroquine; Cyclic N-Oxides; Glioblastoma; Hemin; Humans; Intracellular Membranes; Iron; Lipid Peroxidation; Lysosomes; Membrane Lipids; Oxidants; Oxidation-Reduction; Oxidative Stress; Plasmodium; Radiation-Sensitizing Agents; Sesquiterpenes; Spin Labels	2006
Antimalarial drugs disrupt ion homeostasis in malarial parasites. Memorias do Instituto Oswaldo Cruz, 2007, Volume: 102, Issue:3 Topics: Acridine Orange; Animals; Antimalarials; Artemisinins; Chloroquine; Erythrocytes; Female; Fluorescent Dyes; Homeostasis; Hydrogen-Ion Concentration; Ion Channels; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Plasmodium chabaudi	2007
Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites. Molecular microbiology, 2007, Volume: 65, Issue:1 Topics: Amino Acid Sequence; Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Genes, Protozoan; Humans; Mice; Mice, Inbred CBA; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium chabaudi; Sesquiterpenes; Ubiquitin	2007
Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs). Malaria journal, 2007, Jul-10, Volume: 6 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy; Drug Therapy, Combination; Humans; Malaria; Malawi; Pyrimethamine; Rwanda; Senegal; Sulfadoxine; Tanzania; Zimbabwe	2007
Trioxaquines and heme-artemisinin adducts inhibit the in vitro formation of hemozoin better than chloroquine. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Alkylation; Animals; Antimalarials; Artemisinins; Chloroquine; Dioxanes; Heme; Hemeproteins; Plasmodium; Sesquiterpenes; Spectrophotometry, Infrared	2007
Susceptibility to chloroquine, mefloquine and artemisinin of Plasmodium vivax in northwestern Thailand. Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:19-20 Supp Topics: Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Lethal Dose 50; Malaria, Vivax; Mefloquine; Plasmodium vivax; Survival Rate; Thailand; Treatment Outcome	2007
From chloroquine to artemether-lumefantrine: the process of drug policy change in Zambia. Malaria journal, 2008, Jan-29, Volume: 7 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Planning Guidelines; Health Policy; Humans; Lumefantrine; Malaria; Zambia	2008
Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali. International journal for parasitology, 2008, Volume: 38, Issue:7 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Microbial; Enzyme-Linked Immunosorbent Assay; Genetic Markers; Malaria, Falciparum; Mali; Parasitic Sensitivity Tests; Plasmodium falciparum	2008
Malaria control in South Africa - challenges and successes. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2007, Volume: 97, Issue:11 Pt 3 Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Chloroquine; History, 19th Century; History, 20th Century; HIV Infections; Humans; Malaria; Mosquito Control; South Africa; Travel	2007
In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes. International journal for parasitology, 2008, Volume: 38, Issue:7 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Microbial; Global Health; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum	2008
In vitro activity of artemisinin in combination with clotrimazole or heat-treated amphotericin B against Plasmodium falciparum. The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:5 Topics: Amphotericin B; Animals; Antimalarials; Artemisinins; Chloroquine; Clotrimazole; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Hot Temperature; Plasmodium falciparum	2008
[Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso]. Bulletin de la Societe de pathologie exotique (1990), 2008, Volume: 101, Issue:2 Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Burkina Faso; Child; Chloroquine; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Utilization; Educational Status; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Male; Middle Aged; Motivation; Pharmacies; Pyrimethamine; Self Medication; Sulfadoxine; Urban Population	2008
The inhibitory effect of 2-halo derivatives of D-glucose on glycolysis and on the proliferation of the human malaria parasite Plasmodium falciparum. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:2 Topics: Adenosine Triphosphate; Animals; Antimalarials; Artemisinins; Chloroquine; Deoxyglucose; Fluorodeoxyglucose F18; Glycolysis; Hydrogen-Ion Concentration; Phosphorylation; Plasmodium falciparum	2008
Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda. Wiener klinische Wochenschrift, 2008, Volume: 120, Issue:19-20 Supp Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Developing Countries; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Ethanolamines; Evidence-Based Medicine; Female; Fluorenes; Health Surveys; Humans; Incidence; Infant; Lumefantrine; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Refugees; Uganda; Young Adult	2008
Assessment of malaria in vitro drug combination screening and mixed-strain infections using the malaria Sybr green I-based fluorescence assay. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6 Topics: Animals; Antimalarials; Artemisinins; Benzothiazoles; Chloroquine; Diamines; Drug Combinations; Drug Evaluation, Preclinical; Drug Interactions; Fluorescent Dyes; Hypoxanthine; Mefloquine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines	2009
Dual labeling with a far red probe permits analysis of growth and oxidative stress in P. falciparum-infected erythrocytes. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2010, Volume: 77, Issue:3 Topics: Animals; Artemisinins; Catalase; Chloroquine; Cysteine Proteases; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Humans; Malaria; Models, Biological; Nucleic Acids; Oxidative Stress; Oxygen; Plasmodium falciparum	2010
A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal. The American journal of tropical medicine and hygiene, 2010, Volume: 82, Issue:2 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Fluorescent Dyes; Genotype; Humans; Indoles; Malaria, Falciparum; Plasmodium falciparum; Senegal; Staining and Labeling	2010
Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes. Malaria journal, 2010, Feb-11, Volume: 9 Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Chloroquine; Drug Evaluation, Preclinical; Flow Cytometry; Inhibitory Concentration 50; Malaria, Falciparum; Microscopy; Parasitemia; Parasitic Sensitivity Tests; Plasmodium falciparum; Primaquine; Xanthurenates	2010
Demand for malaria drug soars. Nature, 2010, Aug-05, Volume: 466, Issue:7307 Topics: Agriculture; Artemisia annua; Artemisinins; Chloroquine; Drug Costs; Drug Resistance; Humans; Malaria	2010
Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs. Experimental parasitology, 2011, Volume: 127, Issue:1 Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Synergism; Erythrocytes; Flow Cytometry; Humans; Phytosterols; Plasmodium falciparum; Quinine; Solanum; Trophozoites	2011
Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication. Virus research, 2010, Volume: 153, Issue:2 Topics: Antimalarials; Antiviral Agents; Artemisinins; Cells, Cultured; Chloroquine; Enzyme-Linked Immunosorbent Assay; HIV Core Protein p24; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocytes; Pyrimethamine; Virus Replication	2010
Plasmodium berghei K173: selection of resistance to naphthoquine in a mouse model. Experimental parasitology, 2011, Volume: 127, Issue:2 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Ethanolamines; Fluorenes; Lumefantrine; Malaria; Male; Mice; Naphthoquinones; Plasmodium berghei; Pyrimethamine; Random Allocation	2011
Epidemic of Plasmodium falciparum malaria in Central India, an area where chloroquine has been replaced by artemisinin-based combination therapy. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011, Volume: 105, Issue:3 Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Child; Chloroquine; Drug Therapy, Combination; Epidemics; Female; Humans; India; Infant; Infant, Newborn; Insecticide Resistance; Insecticides; Malaria, Falciparum; Male; Prevalence; Rural Health; Treatment Outcome	2011
Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal. Malaria journal, 2011, Apr-01, Volume: 10 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Malaria, Vivax; Nepal; Plasmodium falciparum; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine	2011
Synthesis and in vitro antimalarial activity of tetraoxane-amine/amide conjugates. European journal of medicinal chemistry, 2011, Volume: 46, Issue:7 Topics: Amides; Amines; Animals; Antimalarials; Artemisinins; Cell Line, Tumor; Chlorocebus aethiops; Chloroquine; Dose-Response Relationship, Drug; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Plasmodium falciparum; Structure-Activity Relationship; Tetraoxanes; Vero Cells	2011
Sensitivity of Plasmodium vivax to chloroquine, mefloquine, artemisinin and atovaquone in north-western Thailand. Wiener klinische Wochenschrift, 2011, Volume: 123 Suppl 1 Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Dose-Response Relationship, Drug; Lethal Dose 50; Mefloquine; Plasmodium vivax; Thailand	2011
Extracellular heme enhances the antimalarial activity of artemisinin. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:1 Topics: Antimalarials; Antioxidants; Artemisia; Artemisinins; Chloroquine; Cholesterol, LDL; Fluorescence; Heme; Hemin; Humans; Lipid Peroxidation; Mefloquine; Oxidants; Oxidation-Reduction; Plasmodium falciparum; Quinine; Tryptophan; Vitamin E	2012
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia. The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Saudi Arabia; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult	2012
Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Drug Synergism; Harmaline; Harmine; HSP90 Heat-Shock Proteins; Malaria; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Plasmodium berghei; Plasmodium falciparum; Protein Structure, Quaternary; Protein Structure, Tertiary; Surface Plasmon Resonance	2012
In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon. Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107, Issue:7 Topics: Antimalarials; Artemisia annua; Artemisinins; Brazil; Chloroquine; Drug Synergism; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plant Extracts; Plasmodium falciparum; Quinine	2012
Too much to ask. Nature, 2012, Nov-22, Volume: 491, Issue:7425 Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria	2012
Defining the timing of action of antimalarial drugs against Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:3 Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Chloroquine; Erythrocytes; Flow Cytometry; High-Throughput Screening Assays; Hydroxamic Acids; Inhibitory Concentration 50; Mefloquine; Merozoites; Plasmodium falciparum; Quinine; Quinolines; Schizonts; Time Factors	2013
Molecular monitoring of antimalarial drug resistance among Plasmodium falciparum field isolates from Odisha, India. Acta tropica, 2013, Volume: 126, Issue:1 Topics: Antimalarials; Artemisinins; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mutation, Missense; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine	2013
Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America, 2013, Apr-02, Volume: 110, Issue:14 Topics: Antimalarials; Artemisinins; Chloroquine; Chromatography, Gel; Cysteine Endopeptidases; Hemeproteins; Hemoglobins; Immunoprecipitation; Mass Spectrometry; Multiprotein Complexes; Plasmodium falciparum; Polymerization; Proteolysis; Protozoan Proteins	2013
Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites. Experimental parasitology, 2013, Volume: 134, Issue:2 Topics: Antimalarials; Artemisinins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzamides; Boron Compounds; Chloroquine; Chlorpheniramine; Dibenzocycloheptenes; Drug Interactions; Drug Resistance, Multiple; Erythrocytes; Fluorescent Dyes; Gefitinib; Humans; Imatinib Mesylate; Mefloquine; Piperazines; Plasmodium falciparum; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Quinolines	2013
Comparative study of antimalarial effect of sambiloto (Andrographis paniculata) extract, chloroquine and artemisinin and their combination against plasmodium falciparum in-vitro. Acta medica Indonesiana, 2013, Volume: 45, Issue:1 Topics: Andrographis; Antimalarials; Artemisinins; Cells, Cultured; Chloroquine; Drug Therapy, Combination; Erythrocytes; Humans; Parasitic Sensitivity Tests; Plant Extracts; Plant Stems; Plasmodium falciparum	2013
High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amodiaquine; Antimalarials; Artemisinins; Automation, Laboratory; Chloroquine; Drug Resistance; Drug Therapy, Combination; High-Throughput Screening Assays; Internet; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinine	2013
An image analysis algorithm for malaria parasite stage classification and viability quantification. PloS one, 2013, Volume: 8, Issue:4 Topics: Algorithms; Antimalarials; Artemisinins; Cell Survival; Cells, Cultured; Chloroquine; Erythrocytes; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Indoles; Inhibitory Concentration 50; Microscopy, Fluorescence; Mitochondria; Organic Chemicals; Plasmodium falciparum; Spores, Protozoan	2013
Pro-oxidant properties of indolone-N-oxides in relation to their antimalarial properties. Journal of inorganic biochemistry, 2013, Volume: 126 Topics: Antimalarials; Artemisinins; Chloroquine; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Erythrocyte Membrane; Heme; Hemin; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Iron; Models, Biological; Models, Chemical; Oxidation-Reduction; Protein-Tyrosine Kinases; Reactive Oxygen Species; Solutions; Syk Kinase	2013
Antimalarial and cytotoxic activities of chiral triamines. Bioorganic & medicinal chemistry letters, 2013, Aug-15, Volume: 23, Issue:16 Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Chloroquine; Cyclization; Humans; Plasmodium falciparum; Polyamines; Small Molecule Libraries	2013
An endoperoxide-based hybrid approach to deliver falcipain inhibitors inside malaria parasites. ChemMedChem, 2013, Volume: 8, Issue:9 Topics: Antimalarials; Artemisinins; Binding Sites; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Resistance; Erythrocytes; Ferrous Compounds; Hemoglobins; Humans; Malaria; Molecular Docking Simulation; Plasmodium falciparum; Protein Structure, Tertiary; Structure-Activity Relationship; Sulfones; Tetraoxanes	2013
Trends in antimalarial drug use in Africa. The American journal of tropical medicine and hygiene, 2013, Volume: 89, Issue:5 Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Health Surveys; Humans; Malaria, Falciparum; Models, Statistical; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors	2013
Model system to define pharmacokinetic requirements for antimalarial drug efficacy. Science translational medicine, 2013, Oct-02, Volume: 5, Issue:205 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Humans; Malaria, Falciparum; Mice; Mice, Inbred C57BL; Models, Biological; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Reproducibility of Results; Treatment Outcome	2013
Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum. European journal of medicinal chemistry, 2014, May-22, Volume: 79 Topics: Antimalarials; Apoptosis; Artemisinins; Benzaldehydes; Cell Survival; Cells, Cultured; Chalcones; Chloroquine; Dose-Response Relationship, Drug; Drug Design; Drug Resistance; Fibroblasts; HeLa Cells; Humans; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2014
Quality of antimalarial drugs and antibiotics in Papua New Guinea: a survey of the health facility supply chain. PloS one, 2014, Volume: 9, Issue:5 Topics: Amodiaquine; Amoxicillin; Antimalarials; Artemether; Artemisinins; Biosimilar Pharmaceuticals; Chloroquine; Drug Resistance; Health Facilities; Humans; Malaria, Falciparum; Malaria, Vivax; Papua New Guinea; Primaquine; Quality Control; Quinine	2014
Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents. Organic & biomolecular chemistry, 2014, Jul-28, Volume: 12, Issue:28 Topics: Aminoquinolines; Antimalarials; Artemisinins; Chloroquine; Drug Design; Erythrocytes; Free Radicals; Humans; Hypoxanthine; Inhibitory Concentration 50; Iron; Oxidation-Reduction; Peroxides; Plasmodium falciparum; Tritium	2014
Chloroquine remains effective for treating Plasmodium vivax malaria in Pursat province, Western Cambodia. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Anti-Infective Agents; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Malaria; Plasmodium vivax	2014
Molecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapy. PloS one, 2014, Volume: 9, Issue:9 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Codon; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Haplotypes; Humans; India; Malaria, Falciparum; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine	2014
Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cells. ChemMedChem, 2014, Volume: 9, Issue:12 Topics: Artemisia; Artemisinins; Breast Neoplasms; Cell Survival; Chlorogenic Acid; Chloroquine; Cisplatin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; Plant Extracts	2014
Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Amino Acid Sequence; Antimalarials; Artemisinins; Biological Transport; Chloroquine; Chromosomes; Drug Resistance, Multiple; Erythrocytes; Humans; INDEL Mutation; Malaria, Falciparum; Mefloquine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Quinolines; Thailand	2014
Inhibition of autophagy by chloroquine potentiates synergistically anti-cancer property of artemisinin by promoting ROS dependent apoptosis. Biochimie, 2014, Volume: 107 Pt B Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Artemisinins; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Synergism; Humans; Membrane Potential, Mitochondrial; Reactive Oxygen Species	2014
Implications of Glutathione Levels in the Plasmodium berghei Response to Chloroquine and Artemisinin. PloS one, 2015, Volume: 10, Issue:5 Topics: Animals; Artemisinins; Chloroquine; Drug Resistance; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Plasmodium berghei; Protozoan Proteins	2015
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:8 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Cambodia; Chloroquine; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Young Adult	2015
Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America, 2015, Sep-22, Volume: 112, Issue:38 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Down-Regulation; Drug Resistance; Flow Cytometry; Genes, Reporter; Hemiterpenes; Luciferases; Morpholinos; Organophosphorus Compounds; Parasites; Peptides; Plasmodium falciparum; Protein Biosynthesis; Proteolysis; RNA Splicing; RNA, Messenger; Sequence Analysis, DNA	2015
Enzymes Involved in Pyrophosphate and Calcium Metabolism as Targets for Anti-scuticociliate Chemotherapy. The Journal of eukaryotic microbiology, 2016, Volume: 63, Issue:4 Topics: Animals; Artemisinins; Calcium; Chloroquine; Ciliophora; Ciliophora Infections; Diphosphates; Fish Diseases; Flatfishes; Homeostasis; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Inorganic Pyrophosphatase	2016
Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4 Topics: Antimalarials; Artemisinins; Atovaquone; Benzothiazoles; Biological Assay; Chloroquine; Diamines; DNA, Protozoan; Drug Resistance; Erythrocytes; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Organic Chemicals; Parasitemia; Plasmodium falciparum; Public Health Surveillance; Quinolines; Reproducibility of Results; Sensitivity and Specificity	2016
Antimalarial and cytotoxic properties of Chukrasia tabularis A. Juss and Turraea vogelii Hook F. Ex. Benth. Parasitology research, 2016, Volume: 115, Issue:4 Topics: Animals; Antimalarials; Artemia; Artemisinins; Cell Survival; Chloroquine; Drug Resistance; Malaria; Male; Meliaceae; Mice; Plant Bark; Plant Extracts; Plant Stems; Plasmodium berghei; Plasmodium falciparum	2016
Repetitive live sporozoites inoculation under arteether chemoprophylaxis confers protection against subsequent sporozoite challenge in rodent malaria model. Acta tropica, 2016, Volume: 158 Topics: Animals; Antimalarials; Artemisinins; Chemoprevention; Chloroquine; Female; Immunization; Malaria; Mefloquine; Mice; Parasite Load; Plasmodium yoelii; Primaquine; Sporozoites; Vaccination	2016
Overcoming Chloroquine Resistance in Malaria: Design, Synthesis, and Structure-Activity Relationships of Novel Hybrid Compounds. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5 Topics: Antimalarials; Artemisinins; Chloroquine; Plasmodium falciparum; Structure-Activity Relationship	2016
Malaria wars. Science (New York, N.Y.), 2016, Apr-22, Volume: 352, Issue:6284 Topics: Antimalarials; Artemisinins; Cambodia; Chloroquine; Disease Eradication; Drug Resistance, Microbial; Humans; Malaria, Falciparum; Mekong Valley; Plasmodium falciparum	2016
A link between poor quality antimalarials and malaria drug resistance? Expert review of anti-infective therapy, 2016, Volume: 14, Issue:6 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	2016
Highly active ozonides selected against drug resistant malaria. Memorias do Instituto Oswaldo Cruz, 2016, Jun-07, Volume: 0 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Female; Humans; Malaria, Falciparum; Mefloquine; Mice; Parasitemia; Plasmodium falciparum	2016
Nanomolar Antimalarial Agents against Chloroquine-Resistant Plasmodium falciparum from Medicinal Plants and Their Structure-Activity Relationships. Journal of natural products, 2017, 01-27, Volume: 80, Issue:1 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Inhibitory Concentration 50; Magnoliopsida; Molecular Structure; Plants, Medicinal; Plasmodium falciparum; Structure-Activity Relationship	2017
Influence of the The American journal of tropical medicine and hygiene, 2017, Volume: 96, Issue:3 Topics: Alleles; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Gene Dosage; Genotyping Techniques; Inhibitory Concentration 50; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Thailand	2017
[Practices of caregivers and national recommendations for treatment of malaria in Benin in 2009]. Bulletin de la Societe de pathologie exotique (1990), 2017, Volume: 110, Issue:3 Topics: Antimalarials; Artemisinins; Attitude of Health Personnel; Benin; Caregivers; Chloroquine; Cross-Sectional Studies; Drug Therapy, Combination; Female; Guideline Adherence; Health Knowledge, Attitudes, Practice; Humans; Malaria; Male; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires	2017
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. PloS one, 2017, Volume: 12, Issue:3 Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Computational Biology; Drug Combinations; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Emetine; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil	2017
The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum Drug Resistance, Identification of Species, and Genotyping in a Single Reaction. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Epidemiological Monitoring; Genotyping Techniques; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Reagent Kits, Diagnostic; Sulfadoxine	2017
Confirmation of Plasmodium falciparum in vitro resistance to monodesethylamodiaquine and chloroquine in Dakar, Senegal, in 2015. Malaria journal, 2017, 03-16, Volume: 16, Issue:1 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; Plasmodium falciparum; Senegal	2017
Molecular Profile of Malaria Drug Resistance Markers of Plasmodium falciparum in Suriname. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7 Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Genotype; Malaria; Mutation; Plasmodium falciparum; Protozoan Proteins; Suriname	2017
Nicotinamide inhibits the growth of P. falciparum and enhances the antimalarial effect of artemisinin, chloroquine and pyrimethamine. Molecular and biochemical parasitology, 2017, Volume: 216 Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Humans; Life Cycle Stages; Niacinamide; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine	2017
Molecular analysis demonstrates high prevalence of chloroquine resistance but no evidence of artemisinin resistance in Plasmodium falciparum in the Chittagong Hill Tracts of Bangladesh. Malaria journal, 2017, 08-15, Volume: 16, Issue:1 Topics: Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Bangladesh; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Sequence Analysis, DNA	2017
In vivo and in vitro Models for Scanning Drug Substances in Malaria: Prestudy. Turkiye parazitolojii dergisi, 2017, Volume: 41, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Disease Models, Animal; Drug Evaluation, Preclinical; In Vitro Techniques; Malaria; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plasmodium berghei; Tetracycline	2017
Antimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates. International journal for parasitology. Drugs and drug resistance, 2017, Volume: 7, Issue:3 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Ghana; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum	2017
Hemozoin-induced activation of human monocytes toward M2-like phenotype is partially reversed by antimalarial drugs-chloroquine and artemisinin. MicrobiologyOpen, 2019, Volume: 8, Issue:3 Topics: Antimalarials; Artemisinins; Cell Differentiation; Chloroquine; Hemeproteins; Humans; Immunologic Factors; Monocytes	2019
Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter. Scientific reports, 2018, 09-11, Volume: 8, Issue:1 Topics: Amodiaquine; Antimalarials; Artemisinins; Calcium; Cells, Cultured; Chloroquine; Drug Resistance, Multiple; Erythrocytes; Gene Expression; Hemoglobins; Host-Parasite Interactions; Humans; Ion Transport; Ionophores; Membrane Transport Proteins; Monensin; Mutation; Nigericin; Plasmodium falciparum; Protozoan Proteins; Pyrrolidinones	2018
No Plasmodium falciparum Chloroquine Resistance Transporter and Artemisinin Resistance Mutations, Haiti. Emerging infectious diseases, 2018, Volume: 24, Issue:11 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Haiti; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Middle Aged; Mutation; Plasmodium falciparum; Protozoan Proteins; Surveys and Questionnaires; Young Adult	2018
Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:3 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Aspartic Acid Endopeptidases; Child; Chloroquine; Drug Resistance; Folic Acid Antagonists; Humans; Lumefantrine; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Quinolines; Uganda	2019
Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine. Experimental parasitology, 2019, Volume: 197 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Cell Count; Cell Line; Chloroquine; Doxycycline; Electron Probe Microanalysis; Heme; Hemeproteins; Humans; Leukocytes, Mononuclear; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Monocytes; Peroxidase; Phagocytosis; Primaquine; Pyrimethamine; Quinine; Spectrophotometry; Temperature; U937 Cells	2019
Evaluation of Plasmodium vivax malaria recurrence in Brazil. Malaria journal, 2019, Jan-22, Volume: 18, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Brazil; Child; Child, Preschool; Chloroquine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Incidence; Infant; Infant, Newborn; Malaria, Vivax; Male; Middle Aged; Primaquine; Recurrence; Retrospective Studies; Time Factors; Young Adult	2019
Multiple relapses of Plasmodium vivax malaria acquired from West Africa and association with poor metabolizer CYP2D6 variant: a case report. BMC infectious diseases, 2019, Aug-09, Volume: 19, Issue:1 Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Cytochrome P-450 CYP2D6; Ghana; Humans; Inactivation, Metabolic; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Primaquine; Recurrence	2019
A multilamellar nanoliposome stabilized by interlayer hydrogen bonds increases antimalarial drug efficacy. Nanomedicine : nanotechnology, biology, and medicine, 2019, Volume: 22 Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Cross-Linking Reagents; Drug Delivery Systems; Hydrogen Bonding; Liposomes; Malaria, Falciparum; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Particle Size; Plasmodium falciparum; Treatment Outcome	2019
Antimalarial Drug Resistance Profiling of Plasmodium falciparum Infections in Ghana Using Molecular Inversion Probes and Next-Generation Sequencing. Antimicrobial agents and chemotherapy, 2020, 03-24, Volume: 64, Issue:4 Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Ghana; High-Throughput Nucleotide Sequencing; Humans; Infant; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine	2020
Experimentally Engineered Mutations in a Ubiquitin Hydrolase, UBP-1, Modulate Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7 Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Hydrolases; Malaria, Falciparum; Mutation; Plasmodium berghei; Plasmodium falciparum; Prospective Studies; Protozoan Proteins; Ubiquitin	2020
Ultrastructural alterations in Plasmodium falciparum induced by chalcone derivatives. BMC research notes, 2020, Jun-15, Volume: 13, Issue:1 Topics: Antimalarials; Artemisinins; Cells, Cultured; Chalcones; Chloroquine; Erythrocytes; Microscopy, Electron, Transmission; Plasmodium falciparum	2020
Clinical Probe of Cyp2C82 Mutants in a Malaria Hyperendemic Zone: Evidence from North-Central, Nigeria. Acta medica (Hradec Kralove), 2020, Volume: 63, Issue:3* Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Cytochrome P-450 CYP2C8; Drug Resistance; Female; Humans; Malaria; Male; Nigeria; Pharmacogenomic Testing; Plasmodium falciparum	2020
Elucidation of DNA Repair Function of PfBlm and Potentiation of Artemisinin Action by a Small-Molecule Inhibitor of RecQ Helicase. mSphere, 2020, 11-25, Volume: 5, Issue:6 Topics: Antimalarials; Artemisinins; Chloroquine; DNA Repair; Enzyme Inhibitors; Humans; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; RecQ Helicases	2020
Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda. Parasitology international, 2021, Volume: 81 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Lumefantrine; Mefloquine; Plasmodium falciparum; Quinine; Uganda	2021
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD). Natural product research, 2022, Volume: 36, Issue:20 Topics: Angiotensin-Converting Enzyme 2; Antimalarials; Antiviral Agents; Artemisinins; Binding Sites; Chloroquine; COVID-19 Drug Treatment; Humans; Peptidyl-Dipeptidase A; SARS-CoV-2; Spike Glycoprotein, Coronavirus	2022
Selection of International journal of molecular sciences, 2021, Jun-03, Volume: 22, Issue:11 Topics: Alleles; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Protozoan Proteins	2021
The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures. BMC biology, 2022, 10-22, Volume: 20, Issue:1 Topics: Amyloid beta-Peptides; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Protein Aggregates; Proteome	2022
Monitoring antimalarial drug-resistance markers in Somalia. Parasites, hosts and diseases, 2023, Volume: 61, Issue:1 Topics: Antimalarials; Chloroquine; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Somalia	2023