chloroquine has been researched along with ammonium chloride in 294 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 152 (51.70) | 18.7374 |
| 1990's | 100 (34.01) | 18.2507 |
| 2000's | 26 (8.84) | 29.6817 |
| 2010's | 14 (4.76) | 24.3611 |
| 2020's | 2 (0.68) | 2.80 |
| Authors | Studies |
|---|---|
| Futemma, M; Kobayashi, K; Murayama, K; Nakajima, A | 1 |
| Berg, T; Nilsson, M; Norum, KR; Tolleshaug, H | 1 |
| Clauser, H; Djiane, J; Houdebine, LM | 1 |
| Ascoli, M; Puett, D | 1 |
| Ascoli, M | 1 |
| Hall, CW; Neufeld, EF; Sando, GN; Titus-Dillon, P | 1 |
| Marshall, S; Olefsky, JM | 1 |
| Olsnes, S; Pihl, A; Sandvig, K | 1 |
| Ohkuma, S; Poole, B; Warburton, MJ | 1 |
| Florén, CH; Nilsson, A | 1 |
| Carpenter, G; Cohen, S | 1 |
| Gapud, CP; Keil, W; Reiss, CS | 1 |
| Middleton, B | 1 |
| Morton, PA; Owensby, DA; Schwartz, AL; Underhill, DM | 1 |
| Culty, M; Nguyen, HA; Underhill, CB | 1 |
| Benoliel, AM; Bongrand, P; Maurin, M; Raoult, D | 1 |
| Banerjee, D; Grieninger, G; Mukhopadhyay, G; Oddoux, C; Overton, O; Redman, C; Roy, S; Yu, S | 1 |
| Alpuche Aranda, CM; Loomis, WP; Miller, SI; Swanson, JA | 1 |
| de Chastellier, C; Rabinovitch, M; Veras, PS | 1 |
| Engleman, EG; Rajasekar, S; Ruegg, CL; Stein, BS | 1 |
| Kopin, IJ; Lipsky, RH; Marini, AM; Schwartz, JP | 1 |
| Buxbaum, JD; Caporaso, GL; Gandy, SE; Greengard, P | 1 |
| Evans, DG; Evans, DJ; Graham, DY | 1 |
| Harding, CV | 1 |
| Cárdaba, B; De Andrés, B; Del Pozo, V; Fernández, JC; Gallardo, S; Lahoz, C; Leyva-Cobian, F; Martín, E; Palomino, P; Tramón, P | 1 |
| Hoebel, BG; Maidment, NT; Pothos, E; Rayport, S; Sulzer, D; Sung, HM | 1 |
| Kalina, M; Socher, R | 1 |
| Graham, CM; Hodgson, J; Riska, PF; Thomas, DB | 1 |
| Kung, HF; Nara, PL; Oroszlan, S; Tsai, WP | 1 |
| Berman, J; Nichols, JS; Wiseman, JS; Wypij, DM | 1 |
| Ghosh, PC; Madan, S | 1 |
| Bertoletti, A; Cavalli, A; Chisari, FV; Fiaccadori, F; Fowler, P; Guilhot, S; Margolskee, RF; Moss, B; Penna, A; Valli, A | 1 |
| Basak, S; Turner, H | 1 |
| Authier, F; Desbuquois, B | 1 |
| Gehm, BD; Kuo, WL; Rosner, MR | 1 |
| Anderson, R; Cervin, M; Kooi, C | 1 |
| Crowle, AJ; Dahl, R; May, MH; Ross, E | 1 |
| Legaard, PK; LeGrand, RD; Misfeldt, ML | 1 |
| Kamps, JA; Kruijt, JK; Kuiper, J; Van Berkel, TJ | 1 |
| Buanes, T; Grotmol, T; Ostensen, J; Raeder, MG; Veel, T | 1 |
| Bachhawat, AK; Pillai, S | 1 |
| Mortensen, RF; Tebo, JM | 1 |
| Benacerraf, B; Michalek, MT; Rock, KL | 1 |
| Barker, CJ; Chanter, N; Lax, AJ; Michell, RH; Murphy, AC; Rozengurt, E; Staddon, JM | 1 |
| Bogitsh, BJ; Davenport, GR | 1 |
| Glick, JM; Jerome, WG; Lewis, JC; Mahlberg, FH; Minor, LK; Rothblat, GH | 1 |
| Blum, HE; Gerok, W; Offensperger, S; Offensperger, WB; Walter, E | 1 |
| Byrd, TF; Horwitz, MA | 1 |
| DiCioccio, RA; Mahoney, CM | 1 |
| Randolph, VB; Stollar, V; Winkler, G | 1 |
| Arik, L; Foster, CJ; Johnson, GR; Pitts, BJ | 1 |
| Gromeier, M; Wetz, K | 1 |
| Henk, WG; Payne, HR; Storz, J | 1 |
| Donovan, MG; Storm, DR | 1 |
| Clem, LW; Jørgensen, T; Miller, NW; Vallejo, AN | 1 |
| Gordon, AH; Hart, PD; Young, MR | 1 |
| Anderson, SK; DeSantes, K; Geissler, F; Press, OW | 1 |
| Beauloye, V; Biélande, V; Jadot, M; Wattiaux, R; Wattiaux-De Coninck, S | 1 |
| Foster, RF; Goff, JP; Haye, KR; Kaufman, SJ | 1 |
| Gluzman, IY; Krogstad, DJ; Murphy, CF; Ravdin, JI; Schlesinger, PH | 1 |
| Emler, CA; Schalch, DS; Sessions, CM | 1 |
| Buckmaster, MJ; Fritsch, JE; Storrie, B | 1 |
| Cardelli, JA; Miears, D; Richardson, J | 1 |
| Chaturvedi, UC; Mathur, A; Rizvi, N | 1 |
| Kawashima, S; Shimizu, A | 1 |
| Jamieson, JC; Lammers, G | 1 |
| Adorini, L; Appella, E; Cardinaux, F; Doria, G; Nagy, ZA | 1 |
| Black, SJ; Vandeweerd, V | 1 |
| Hameed, A; Lee, MK; Lichtenheld, MG; Olsen, KJ; Podack, ER | 1 |
| Moss, AL; Ward, WF | 1 |
| Simpson, LI | 1 |
| Bland, PW; Whiting, CV | 1 |
| Burns, WB; Cheung, HS; Kwong, CH | 1 |
| Drasar, BS; Harley, VS | 1 |
| Christensen, JR; Peters, TJ; Rideout, JM; Smith, GD | 1 |
| Gluzman, IY; Krogstad, DJ; Schlesinger, PH | 1 |
| Kiyotani, K; Sakaguchi, T; Takao, S; Yoshida, T | 1 |
| Kondor-Koch, C; Parczyk, K | 1 |
| Berman, JD; Ray, P | 1 |
| Deepe, GS; Harris, JE | 1 |
| Upcroft, P | 1 |
| Esparza, J; Gil, F; Liprandi, F; Ludert, JE; Michelangeli, F | 1 |
| Fukuhara, N; Ishida, N; Kitaoka, S; Konno, T; Yoshie, O | 1 |
| Arnljots, K; Lantz, M; Olsson, I; Persson, AM | 1 |
| Keating, MT; Williams, LT | 1 |
| Greenberg, HB; Kaljot, KT; Rubin, DH; Shaw, RD | 1 |
| Frank, BH; Herrman, J; Rabkin, R; Simmons, RE | 1 |
| Maeda, M; Neda, H; Niitsu, Y; Sone, H; Urushizaki, I; Watanabe, N; Yamauchi, N | 1 |
| Habermehl, KO; Wetz, K; Willingmann, P; Zeichhardt, H | 1 |
| Presky, DH; Schonbrunn, A | 1 |
| Gordon, VM; Hewlett, EL; Leppla, SH | 1 |
| Bülow, R; Nonnengässer, C; Overath, P | 1 |
| Barrera, R; Coutiño, R; González-Noriega, A; Saavedra, VM | 1 |
| Glushakova, SE; Lukashevich, IS | 1 |
| Antoine, JC; Feldmann, G; Goud, B; Jouanne, C; Maurice, M | 1 |
| Braulke, T; Gartung, C; Hasilik, A; von Figura, K | 1 |
| Banno, Y; Nozawa, Y; Sasaki, N | 1 |
| Maeda, H; Oda, T; Sato, F | 1 |
| Dumont, JE; Ketelbant, P; Unger, J | 1 |
| Cheung, HS; McCarty, DJ | 1 |
| Bagchi, N; Brown, TR; Shivers, B | 1 |
| Klempner, MS; Styrt, B | 2 |
| Lebon, P | 1 |
| Dills, DG; Emler, CA; Farley, AC; Masakawa, A; Schalch, DS; Sessions, CM | 1 |
| Olsson, I; Persson, AM; Strömberg, K | 1 |
| Akin, DT; Kinkade, JM | 1 |
| Black, JD; Dolly, JO | 1 |
| Goldwasser, E; Krantz, SB; Sawyer, ST | 1 |
| Baxt, B | 1 |
| Braulke, T; Geuze, HJ; Hasilik, A; Slot, JW; von Figura, K | 1 |
| Cluff, CW; Orlin, CA; Ziegler, HK | 1 |
| Amano, J; Kato, K; Nishimura, Y; Sato, H; Tsuji, H | 1 |
| Morgan, EH; Sorokin, LM; Yeoh, GC | 1 |
| Bertini, F; Colombo, MI | 1 |
| Ames, RS; Fry, K; Lee, HM; Roth, JA; Scannon, PJ | 1 |
| Bauer, A; Kirchner, H; Rutenfranz, I | 1 |
| Just, WW; Zhang, Y | 1 |
| Zhang, Y | 1 |
| Bednarczyk, JL; Capra, JD | 1 |
| Farías, G; Kiss, J; Kuznar, J; Navarrete, E | 1 |
| Anderson, RG; Kamen, BA; Peryea, X; Streckfuss, AJ; Wang, MT | 1 |
| Akiyama, T; Matsumoto, J; Oikawa, A; Saeki, H | 1 |
| Ginsburg, H; Krugliak, M; Zarchin, S | 1 |
| Carpentier, JL; Fehlmann, M; Freychet, P; Gazzano, H; Orci, L; Van Obberghen, E | 1 |
| Chander, A; Fisher, AB; Reicherter, J | 1 |
| Matsumoto, Y; Suga, T | 1 |
| Benacerraf, B; Falo, LD; Rock, KL; Rothstein, L | 1 |
| Colofiore, JR; Schwartz, ER | 1 |
| Cook, JS; Fishman, JB | 1 |
| Decker, ML; Decker, RS; Fuseler, JW; Thomas, V | 1 |
| Cabantchik, ZI; Ginsburg, H; Yayon, A | 2 |
| Bonser, AM; Garcia-Webb, P | 1 |
| Chen, GL; Chen, WW; Frayer, KL; Sutrina, SL | 1 |
| Den, H | 1 |
| Dijkstra, J; Regts, D; Scherphof, G; van Galen, M | 1 |
| Bowen, BJ; Douglas, AJ; McArdle, HJ; Morgan, EH | 1 |
| Carrasco, L; Castrillo, JL; Muñoz, A | 1 |
| Andersen, KB | 1 |
| Jagendorf, AT; Nishizaki, Y | 1 |
| Koyama, AH; Uchida, T | 1 |
| Camargo, MJ; Maack, T; Sumpio, BE | 1 |
| Harkes, L; Kruijt, JK; Nagelkerke, JF; Van Berkel, TJ | 1 |
| Armstrong, NJ; Morgan, EH | 1 |
| Iacopetta, BJ; Morgan, EH | 1 |
| Superti, F; Tsiang, H | 1 |
| Houdebine, LM | 1 |
| Berg, T; Carlander, B; Drevon, CA; Tolleshaug, H | 1 |
| Ausiello, C; Rossi, GB; Ruggiero, V; Sorrentino, V | 1 |
| Berg, RA; Neblock, DS | 2 |
| Djiane, J; Houdebine, LM | 1 |
| DiSorbo, DM; Litwack, G; Moriarity, DM; Savage, CR | 1 |
| De Groot, PG; Hollemans, M; Meera Khan, P; Ovde Elferink, RO; Strijland, A; Tager, JM; Westerveld, A | 1 |
| Schlesinger, P; Stahl, P; Tietze, C | 2 |
| Delouis, C; Djiane, J; Kelly, PA | 1 |
| Hamaguchi, M; Nagai, Y; Toyoda, T; Yoshida, T | 1 |
| Dupuy, JM; Krzystyniak, K | 1 |
| Campos, RH; Carrillo, EC; Giachetti, C | 1 |
| Fitzgerald, DJ; Pastan, I; Seth, P; Willingham, MC | 1 |
| Berkower, IJ; Berzofsky, JA; Busch, M; Gurd, FR; Streicher, HZ | 1 |
| Friend, DS; Hong, K; Papahadjopoulos, D; Straubinger, RM | 1 |
| Oikawa, A; Saeki, H | 1 |
| Derer, M; Superti, F; Tsiang, H | 1 |
| Bystryn, JC; Johnston, D | 1 |
| Jacewicz, M; Keusch, GT | 1 |
| Fujimori, K; Imai, K; Takano, Y; Tanaka, A; Yamada, M; Yamamoto, K | 1 |
| Cheung, HS; Evans, RW; McCarty, DJ | 1 |
| Hare, JF; Huston, M | 1 |
| Brown, DT; Cassell, S; Edwards, J | 1 |
| Casey, ML; Johnston, JM; MacDonald, PC | 1 |
| Decker, RS; Fuseler, JF | 1 |
| Forsbeck, K; Nilsson, K | 1 |
| Helgeland, K | 1 |
| Oppenheim, JJ; Scala, G | 1 |
| Ando, M; Furuno, K; Kato, K; Kuwano, M; Ono, M; Shimada, T | 1 |
| Dijkstra, J; Scherphof, GL; Van Galen, M | 1 |
| Goodman, HM; Gorin, E; Grichting, G | 1 |
| Armstrong, NJ; Iacopetta, BJ; McArdle, HJ; Morgan, EH; Paterson, S | 1 |
| Garvin, AJ; Lyubsky, S; Poore, CM | 1 |
| Unanue, ER; Ziegler, HK | 1 |
| Rechsteiner, M; Rote, KV | 1 |
| Duckworth, WC; Halban, PA; Runyan, KR; Solomon, SS; Wright, RK | 1 |
| Kent, C | 1 |
| Helenius, A; Marsh, M; White, J | 1 |
| Hostetler, KY; Richman, DD | 1 |
| Gonzalez-Noriega, A; Grubb, JH; Sly, WS; Talkad, V | 1 |
| Aulinskas, TH; Coetzee, GA; van der Westhuyzen, DR | 1 |
| Lin, MC; Taniuchi, M | 1 |
| Elliott, KR; Houslay, MD | 1 |
| Canivet, B; Carpentier, JL; Freychet, P; Gorden, P; Orci, L | 1 |
| Geisow, MJ; Hart, PD; Young, MR | 1 |
| Brady, RO; Kusiak, JW; Quirk, JM | 1 |
| Brown, MS; Goldstein, JL; Ho, YK | 1 |
| Talbot, PJ; Vance, DE | 1 |
| Olsnes, S; Sandvig, K | 1 |
| Bens, M; Bourbouze, R; Cluzeaud, F; Riccaldi, D; Robic, D; Vandewalle, A; Wu, MS | 1 |
| Bunnett, NW; Garland, AM; Grady, EF; Payan, DG; Vigna, SR | 1 |
| Breuer, W; Cabantchik, ZI; Epsztejn, S | 1 |
| al-Jaufy, AY; Jackson, MP; King, SR | 1 |
| Merrill, AH; Smith, ER | 1 |
| Aerts, H; Renkema, H; Schurr, E; van Es, HH | 1 |
| Lüllmann-Rauch, R; Pods, R; Von Witzendorff, B | 1 |
| Beyreuther, K; Fuller, SJ; Li, QX; Masters, CL; Smith, AI; Storey, E | 1 |
| Ortiz-Ordóñez, JC; Sechelski, JB; Seed, JR | 1 |
| Albert, MJ; Ansaruzzaman, M; Bhuiyan, NA; Faruque, AS; Neogi, PK | 1 |
| Mendez, AJ | 1 |
| Esko, JD; Hager, KM; Hajduk, SL; Moore, DR; Pierce, MA; Tytler, EM | 1 |
| Lobie, PE; Mertani, H; Morales-Bustos, O; Morel, G; Norstedt, G; Waters, MJ | 1 |
| Hajjar, KA; Reynolds, CM | 1 |
| Chang, SC; Ong, SJ; Su, HM; Tai, JH | 1 |
| Loss, GE; Sant, AJ | 1 |
| Getz, GS; Reardon, CA; Ye, SQ | 1 |
| Lodish, HF; Neumann, D; Watowich, SS; Wikström, L | 1 |
| Beyreuther, K; Czech, C; Dyrks, T; Reinsch, C; Turner, J; Urmoneit, B | 1 |
| Evans, SG; Havlik, I | 1 |
| Anderson, RG; Mineo, C | 1 |
| Hoidal, JR; Marshall, BC; Rao, GV; Rao, NV | 1 |
| Haynes, DR; Howie, DW; Pearcy, MJ; Rogers, SD; Vernon-Roberts, B | 1 |
| Frey, TK; Macchia, S; Mastromarino, P; Orsi, N; Petruzziello, R; Rieti, S | 1 |
| Bale, LK; Clarkson, JT; Conover, CA | 1 |
| Everitt, E; Rodríguez, E | 2 |
| Alonso, M; Hendricks, L; Hidalgo, J; Velasco, A | 1 |
| Augustijns, PF | 1 |
| Paganetti, PA; Schrader-Fischer, G | 1 |
| Ackermann, MR; Kreutz, LC | 1 |
| Bray, PG; Hawley, SR; Park, BK; Ward, SA | 1 |
| Busch, GL; Gulbins, E; Hamprecht, B; Lang, F; Wagner, HJ; Wiesinger, H | 1 |
| Batuman, V; Guan, S | 1 |
| Dantuma, NP; Diederen, JH; Pijnenburg, MA; Van der Horst, DJ | 1 |
| Ohkuma, S; Takano, T | 1 |
| Dzau, VJ; Hein, L; Kobilka, BK; Meinel, L; Pratt, RE | 1 |
| Harrison, TS; Levitz, SM; Liu, X; Tabuni, A | 1 |
| Cnop, M; Grupping, AY; Hannaert, JC; Pipeleers, DG; Van Berkel, TJ; Van Schravendijk, CF | 1 |
| Cubitt, B; de la Torre, JC; Gonzalez-Dunia, D | 1 |
| Balaji, KN; Boom, WH | 1 |
| Loegering, DJ; Raley, MJ; Schwacha, MG | 1 |
| Bates, P; Wool-Lewis, RJ | 1 |
| Fominaya, J; Uherek, C; Wels, W | 1 |
| Bernardes, C; Cruz, B; Geraldes, A; Valdeira, ML | 1 |
| Beyer, EC; Green, K; Laing, JG; Saffitz, JE; Tadros, PN | 1 |
| Kulda, J; Schrével, J; Suchan, P; Tachezy, J | 1 |
| Goodyer, CG; LeBlanc, AC | 1 |
| Dittmer, F; von Figura, K | 1 |
| Friedmann, JM; Thévenod, F | 1 |
| Bodaghi, B; Bruggeman, CA; LeHoang, P; Michelson, S; Perret, E; Slobbe-van Drunen, ME; Topilko, A; van Dam-Mieras, MC; Virelizier, JL; Vossen, RC; Zipeto, D | 1 |
| Alonso, MA; Puertollano, R | 1 |
| Brech, A; Dannevig, BH; Eliassen, TM; Falk, K; Frøystad, MK; Gjøen, T; Jankowska, M; Romøren, K | 1 |
| Akisaka, T; Inoue, M; Yoshida, H | 1 |
| Bang, KW; Blanchette, VS; Freedman, J; Semple, JW; Speck, ER | 1 |
| Fayadat, L; Franc, JL; Lanet, J; Siffroi-Fernandez, S | 1 |
| Ferreira, DF; Rebello, MA; Rebello, MCS; Santo, MPE | 1 |
| Catisti, R; Docampo, R; Rodrigues, CO; Vercesi, AE | 1 |
| Kubota, Y; Patrick, G; Takahashi, I; Takahashi, S | 1 |
| Brown, DT; Hernandez, R; Luo, T | 1 |
| Levitz, SM; Weber, SM | 1 |
| Guili, V; Jullien, J; Reichardt, LF; Rudkin, BB | 1 |
| Brojatsch, J; Diaz-Griffero, F; Hoschander, SA | 1 |
| Benveniste, EN; Choi, C; Kwon, D; Oh, JW; Park, J | 1 |
| Chiovato, L; Lisi, S; Marinò, M; McCluskey, RT; Pinchera, A | 1 |
| BERNSTEIN, HN; RUBIN, M; ZVAIFLER, NJ | 1 |
| Egan, J; Hoppe, HC; Meredith, SA; van Schalkwyk, DA; Weber, BW; Wiehart, UI | 1 |
| Cowan, JW; Deng, L; Frank, SJ; He, K; Jiang, J; Li, X; Loesch, K; Wang, X | 1 |
| Benjannet, S; Bergeron, E; Erickson, BR; Ksiazek, TG; Nichol, ST; Rollin, PE; Seidah, NG; Vincent, MJ | 1 |
| Allen, LA; Schwartz, JT | 1 |
| Steffen, AC; Sundberg, AL | 1 |
| Campitelli, L; Cassone, A; D'Ostilio, D; Di Trani, L; Donatelli, I; Norelli, S; Puzelli, S; Savarino, A; Vignolo, E | 1 |
| Adachi, K; Ichinose, T; Kitazato, K; Kobayashi, N; Takizawa, N; Watanabe, K | 1 |
| Delputte, PL; Misinzo, G; Nauwynck, HJ | 1 |
| Delputte, PL; Lefebvre, DJ; Misinzo, G; Nauwynck, HJ | 1 |
| de Boer, TP; Jansen, JA; van der Heyden, MA; van Rijen, HV; van Veen, TA; Vos, MA; Wolswinkel, R | 1 |
| Habuchi, O; Kimata, K; Kondo, S; Matsumura, K; Morisaki, T; Ohtake, S | 1 |
| Kikuchi, H; Oite, T; Serikawa, T; Tanaka, K | 1 |
| Qiao, L; Zhang, J | 1 |
| Jia, L; Wang, MM; Yu, G; Zhang, Y | 1 |
| Behera, SP; Dubey, SC; Mathapati, BS; Mishra, N; Nema, RK; Rajukumar, K | 1 |
| Huang, YB; Liu, CB; Wang, H; Wu, JF; Zhong, CY | 1 |
| Feng, Y; Yan, T; Zhai, Q; Zheng, J | 1 |
| Mallapragada, S; Zhang, B | 1 |
| Chen, J; Ding, Q; Guo, W; Huang, H; Li, Z; Mai, J; Xu, Y; Yang, Y | 1 |
| Ashfaq, UA; Javed, T; Nawaz, Z; Rehman, S; Riazuddin, S | 1 |
| Ann, EJ; Kim, MY; Kim, SM; Mo, JS; Park, HS; Yoon, JH | 1 |
| Lefort, R; Pozueta, J; Shelanski, M | 1 |
| Hsieh, SC; Li, KJ; Tsai, CY; Wu, CH; Yu, CL | 1 |
| Bahlmann, AS; Eichenseher, F; Furrer, A; Leimer, N; Loessner, MJ; Matt, U; Palheiros Marques, M; Rachmühl, C; Schuepbach, RA; Seidl, K; Zinkernagel, AS | 1 |
| Jeong, K; Jeong, MS; Kim, SH; Kwon, HY; Sohn, EJ | 1 |
| Chen, S; Jia, P; Qi, X; Wang, J; Wang, T; Wang, X; Xue, Q; Xue, T; Yang, B | 1 |
| Cui, L; Hua, X; Shen, X; Yu, X; Zhang, Z; Zhao, T | 1 |
| de Jong, OG; de Miguel Perez, D; Kooijmans, SA; Ortega, FG; Roefs, MT; Schiffelers, RM; Sluijter, JP; Vader, P | 1 |
| Cong, J; Ge, C; Jin, N; Li, T; Li, X; Li, Y; Lu, J; Shang, C; Tian, M; Zhang, H; Zhu, Y; Zhuang, X | 1 |
| Ahmed, R; Bharate, SB; Chandra, A; Das, S; Godbole, R; Guha, A; Gulzar, SE; Jahnavi, S; Lingamallu, SM; Mahajan, B; Mayor, S; Najar, AH; Nuthakki, VK; Panikulam, P; Prabhakara, C; Puthiyapurayil, TP; Sheth, D; Shivaraj, A; Sil, P; Singh, PP; Subhash, N; Sundaramurthy, V; U, I; van Zanten, TS; Vemula, P; Vishwakarma, R | 1 |
1 review(s) available for chloroquine and ammonium chloride
| Article | Year |
|---|---|
Chloroquine and acid vesicle function.
Topics: Ammonium Chloride; Animals; Chloroquine; Drug Resistance; Hydrogen-Ion Concentration; Organelles; Plasmodium falciparum | 1989 |
293 other study(ies) available for chloroquine and ammonium chloride
| Article | Year |
|---|---|
[Effect of ammonium chloride on the excretion of chloroquine in rabbit urine (author's transl)].
Topics: Ammonium Chloride; Animals; Chloroquine; Hydrogen-Ion Concentration; Rabbits | 1977 |
Uptake and degradation of 125I-labelled asialo-fetuin by isolated rat hepatocytes.
Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Biological Transport; Chloroquine; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Liver; Male; Rats; Sialic Acids; Subcellular Fractions | 1977 |
[Role of lysosomes, microtubules and microfilaments in the mechanism of the lactogenic action of prolactin in the rabbit mammary gland].
Topics: Ammonium Chloride; Animals; Caseins; Cattle; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Female; In Vitro Techniques; Lactation; Lysosomes; Mammary Glands, Animal; Microtubules; Pregnancy; Prolactin; Pseudopregnancy; Rabbits | 1979 |
Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors.
Topics: Ammonium Chloride; Animals; Chloroquine; Chorionic Gonadotropin; Kinetics; Leydig Cell Tumor; Male; Mice; Protease Inhibitors; Receptors, Cell Surface; Steroids; Trypsin Inhibitors | 1978 |
Demonstration of a direct effect of inhibitors of the degradation of receptor-bound human choriogonadotropin on the steroidogenic pathway.
Topics: Ammonium Chloride; Animals; Chloroquine; Chorionic Gonadotropin; Cyanides; Deoxy Sugars; Deoxyglucose; Kinetics; Leydig Cell Tumor; Male; Mice; Protease Inhibitors; Receptors, Cell Surface; Steroids | 1978 |
Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia.
Topics: Ammonium Chloride; Biological Transport; Cells, Cultured; Chloroquine; Dextrans; Dose-Response Relationship, Drug; Glycoside Hydrolases; Iduronidase; Kinetics; Mannosephosphates; Procaine; Receptors, Drug | 1979 |
Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation.
Topics: Adipose Tissue; Ammonium Chloride; Animals; Chloroquine; Dinitrophenols; Ethylmaleimide; Fluorides; In Vitro Techniques; Insulin; Kinetics; Male; Rats; Receptor, Insulin; Trypsin | 1979 |
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells.
Topics: Ammonium Chloride; Biological Transport; Chloroquine; Diphtheria Toxin; Dose-Response Relationship, Drug; HeLa Cells; Humans; Kinetics; Lectins; Ribosome Inactivating Proteins, Type 2; Toxins, Biological | 1979 |
The accumulation of weakly basic substances in lysosomes and the inhibition of intracellular protein degradation.
Topics: Ammonium Chloride; Animals; Cathepsins; Chloroquine; DNA; Fibroblasts; Kinetics; Lasalocid; Lysosomes; Proteins; Rats | 1977 |
Uptake and degradation of iodine-labelled chylomicron remnant particles by monolayers of rat hepatocytes.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Chylomicrons; Colchicine; Concanavalin A; Electrophoresis, Polyacrylamide Gel; Lipid Metabolism; Liver; Male; Proteins; Rats | 1978 |
125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.
Topics: Ammonium Chloride; Anesthetics, Local; Azides; Binding, Competitive; Cell Membrane; Chloroquine; Cyanides; Cycloheximide; Dinitrophenols; Epidermal Growth Factor; Fibroblasts; Fluorides; Humans; Iodine Radioisotopes; Kinetics; Peptides; Temperature; Trypsin Inhibitors | 1976 |
Newly synthesized class II MHC chains are required for VSV G presentation to CTL clones.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Antigens, Viral; Brefeldin A; Chloroquine; Clone Cells; Cyclopentanes; Emetine; Glycoproteins; Histocompatibility Antigens Class II; Lymphocyte Cooperation; Membrane Glycoproteins; Mice; Recombinant Proteins; Solubility; T-Lymphocytes, Cytotoxic; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1992 |
Lysosome inhibitors enhance the ability of cyclic AMP-elevating agents to induce the LDL receptor in human vascular smooth muscle cells.
Topics: Alprostadil; Ammonium Chloride; Cells, Cultured; Chloroquine; Colforsin; Cyclic AMP; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lipoproteins, LDL; Lysosomes; Muscle, Smooth, Vascular; Receptors, LDL | 1992 |
Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells.
Topics: Ammonium Chloride; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Chloroquine; Endocytosis; Humans; Kinetics; Leupeptins; Liver Neoplasms; Lysosomes; Pepstatins; Plasminogen Activator Inhibitor 1; Primaquine; Recombinant Proteins; Subcellular Fractions; Tissue Plasminogen Activator; Tumor Cells, Cultured | 1992 |
The hyaluronan receptor (CD44) participates in the uptake and degradation of hyaluronan.
Topics: Ammonium Chloride; Animals; Antibodies, Monoclonal; Cell Line, Transformed; Chloroquine; Fluorescein; Fluoresceins; Hyaluronan Receptors; Hyaluronic Acid; Hyaluronoglucosaminidase; Lysosomes; Macrophages, Alveolar; Mice; Receptors, Cell Surface; Receptors, Lymphocyte Homing | 1992 |
Phagolysosomal alkalinization and the bactericidal effect of antibiotics: the Coxiella burnetii paradigm.
Topics: Amantadine; Ammonium Chloride; Animals; Anti-Bacterial Agents; Cell Line; Chloroquine; Coxiella burnetii; Doxycycline; Hydrogen-Ion Concentration; Lysosomes; Macrophages; Mice; Pefloxacin; Phagocytosis; Rifampin | 1992 |
Assembly and secretion of fibrinogen. Degradation of individual chains.
Topics: Ammonium Chloride; Animals; Cell Line; Chickens; Chloroquine; Fibrinogen; Humans; Kinetics; Leupeptins; Liver; Lysosomes; Macromolecular Substances; Methionine; Sulfur Radioisotopes; Transfection; Tumor Cells, Cultured | 1992 |
Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes.
Topics: Ammonium Chloride; Animals; beta-Galactosidase; Cell Line; Chloroquine; Gene Expression Regulation, Bacterial; Genes, Bacterial; Humans; Hydrogen-Ion Concentration; Kinetics; Macrophages; Phagocytosis; Salmonella typhimurium; Transcription, Genetic; Virulence | 1992 |
Transfer of zymosan (yeast cell walls) to the parasitophorous vacuoles of macrophages infected with Leishmania amazonensis.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cytochalasin D; Hydrogen-Ion Concentration; Kinetics; Leishmaniasis; Macrophages; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Monensin; Temperature; Vacuoles; Zymosan | 1992 |
Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3.
Topics: Alkaloids; Ammonium Chloride; CD4 Antigens; Chloroquine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Humans; Monensin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Radioimmunoprecipitation Assay; Staurosporine; T-Lymphocytes | 1992 |
Accumulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultured cerebellar astrocytes.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Ammonium Chloride; Animals; Astrocytes; Cells, Cultured; Cerebellum; Chloroquine; Lysosomes | 1992 |
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.
Topics: Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Autoradiography; Brefeldin A; Chloroquine; Cyclopentanes; Glycosylation; Kinetics; Methionine; Molecular Weight; Monensin; Organelles; PC12 Cells; Protein Processing, Post-Translational; Sulfur Radioisotopes; Time Factors | 1992 |
Adherence and internalization of Helicobacter pylori by HEp-2 cells.
Topics: Adrenal Glands; Ammonium Chloride; Animals; Bacterial Adhesion; Cadaverine; Cell Line; Chloroquine; Cytochalasin B; Endocytosis; Epithelium; Gastric Mucosa; Helicobacter pylori; Mice; Neuraminidase; Temperature | 1992 |
Electroporation of exogenous antigen into the cytosol for antigen processing and class I major histocompatibility complex (MHC) presentation: weak base amines and hypothermia (18 degrees C) inhibit the class I MHC processing pathway.
Topics: Ammonium Chloride; Animals; Antigens; Chloroquine; Cold Temperature; Cytosol; Golgi Apparatus; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Mice; Mice, Inbred C57BL | 1992 |
Eosinophil as antigen-presenting cell: activation of T cell clones and T cell hybridoma by eosinophils after antigen processing.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Separation; Chloroquine; Eosinophils; Female; Histocompatibility Antigens Class II; Hybridomas; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; T-Lymphocytes | 1992 |
Weak base model of amphetamine action.
Topics: Ammonium Chloride; Amphetamine; Animals; Benztropine; Benzylamines; Chloroquine; Dopamine; Hydrogen-Ion Concentration; Kinetics; Neurons; Nucleus Accumbens; Rats; Time Factors | 1992 |
Endocytosis in cultured rat alveolar type II cells: effect of lysosomotropic weak bases on the processes.
Topics: Ammonium Chloride; Animals; Birefringence; Cells, Cultured; Chloroquine; Endocytosis; Histocytochemistry; Inclusion Bodies; Isoquinolines; Lysosomes; Male; Microscopy, Electron; Microscopy, Polarization; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Inbred Strains; Time Factors | 1991 |
The role of the endoplasmic reticulum in antigen processing. N-glycosylation of influenza hemagglutinin abrogates CD4+ cytotoxic T cell recognition of endogenously processed antigen.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Antigens, Viral; CD4-Positive T-Lymphocytes; Chloroquine; Cytotoxicity, Immunologic; Endoplasmic Reticulum; Epitopes; Glycoproteins; Glycosylation; Hemagglutinins, Viral; Histocompatibility Antigens Class II; Influenza A virus; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Molecular Sequence Data; T-Lymphocytes, Cytotoxic | 1990 |
Inhibition of human immunodeficiency virus infectivity by chloroquine.
Topics: Ammonium Chloride; Animals; Chickens; Chloroquine; Glycoproteins; Glycosylation; HIV-1; Rabbits; RNA-Directed DNA Polymerase; Viral Envelope Proteins | 1990 |
Evidence against a role for aspartyl proteases in intracellular processing of big endothelin.
Topics: Ammonium Chloride; Aspartic Acid; Aspartic Acid Endopeptidases; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Endothelin-1; Endothelins; Endothelium; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Monensin; Pepstatins; Protein Precursors | 1991 |
Interaction of gelonin with macrophages: effect of lysosomotropic amines.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Cytotoxins; Kinetics; Leucine; Macrophages; Mannans; Mice; Phagocytosis; Pinocytosis; Plant Proteins; Ribosome Inactivating Proteins, Type 1 | 1992 |
Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens.
Topics: Ammonium Chloride; Antigens, Viral; Antiviral Agents; Brefeldin A; CD4 Antigens; Chloroquine; Clone Cells; Cyclopentanes; Hepatitis B; Hepatitis B virus; HLA-D Antigens; Humans; Recombination, Genetic; T-Lymphocytes, Cytotoxic; Vaccinia virus; Viral Envelope Proteins | 1992 |
Infectious entry pathway for canine parvovirus.
Topics: Ammonium Chloride; Animals; Antigens, Viral; Cell Line; Chloroquine; DNA, Viral; Dogs; Endocytosis; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; Microscopy, Electron; Parvoviridae; Virus Replication | 1992 |
Degradation of glucagon in isolated liver endosomes. ATP-dependence and partial characterization of degradation products.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Cadaverine; Cell Fractionation; Cell-Free System; Chloroquine; Endocytosis; Glucagon; Golgi Apparatus; Iodine Radioisotopes; Kinetics; Liver; Male; Methylamines; Organelles; Protease Inhibitors; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains | 1991 |
Regulation of insulin degradation: expression of an evolutionarily conserved insulin-degrading enzyme increases degradation via an intracellular pathway.
Topics: Ammonium Chloride; Animals; Biological Evolution; Cell Line; Chloroquine; DNA; Drosophila; Humans; Insulin; Insulysin; Kinetics; Lysosomes; Plasmids; Recombinant Proteins; Sequence Homology, Nucleic Acid; Transfection | 1991 |
Differentiation of acid-pH-dependent and -nondependent entry pathways for mouse hepatitis virus.
Topics: Acids; Ammonium Chloride; Animals; Cadaverine; Cells, Cultured; Chloroquine; Endocytosis; Fibroblasts; Hydrogen-Ion Concentration; Immunity, Innate; Murine hepatitis virus; Vero Cells; Vesicular stomatitis Indiana virus; Virus Replication | 1991 |
Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic.
Topics: Ammonium Chloride; Cell Fusion; Cells, Cultured; Chloroquine; Humans; Hydrogen-Ion Concentration; Isoniazid; Macrophages; Mycobacterium avium; Mycobacterium tuberculosis; Pyrazinamide; Streptomycin; Virulence | 1991 |
The superantigen Pseudomonas exotoxin A requires additional functions from accessory cells for T lymphocyte proliferation.
Topics: ADP Ribose Transferases; Ammonium Chloride; Animals; Antigen-Presenting Cells; Bacterial Toxins; Cells, Cultured; Chloroquine; Enterotoxins; Exotoxins; Formaldehyde; Histocompatibility Antigens Class II; Interleukin-1; Lectins; Lymphocyte Activation; Mice; Peanut Agglutinin; Polymers; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Receptors, Antigen, T-Cell; T-Lymphocytes; Virulence Factors | 1991 |
Uptake and degradation of human low-density lipoprotein by human liver parenchymal and Kupffer cells in culture.
Topics: Ammonium Chloride; Biological Transport; Calcium; Cells, Cultured; Chloroquine; Edetic Acid; Humans; Kinetics; Kupffer Cells; Lipoproteins, LDL; Liver; Magnesium | 1991 |
Secretin dissipates red acridine orange fluorescence from pancreatic duct epithelium.
Topics: Acridine Orange; Ammonium Chloride; Animals; Carbon Dioxide; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chloroquine; Cytoplasm; Epithelium; Fluoresceins; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Pancreatic Ducts; Secretin; Swine | 1991 |
Distinct intracellular fates of membrane and secretory immunoglobulin heavy chains in a pre-B cell line.
Topics: Ammonium Chloride; Animals; B-Lymphocytes; Brefeldin A; Cell Line, Transformed; Chloroquine; Cyclopentanes; Immunoglobulin A, Secretory; Immunoglobulin Heavy Chains; Immunoglobulin Isotypes; Kinetics; Lysosomes; Monensin; Receptors, Antigen, B-Cell | 1991 |
Internalization and degradation of receptor bound C-reactive protein by U-937 cells: induction of H2O2 production and tumoricidal activity.
Topics: Ammonium Chloride; C-Reactive Protein; Cell Compartmentation; Cell Death; Cell Differentiation; Cell Line; Chloroquine; Endocytosis; Humans; Hydrogen Peroxide; Monensin; Monocytes; Neoplasms, Experimental; Receptors, Immunologic | 1991 |
Weak base amines can inhibit class I MHC-restricted antigen presentation.
Topics: Amines; Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Line; Chloroquine; Histocompatibility Antigens Class I; Hybridomas; Interleukin-2; Lysosomes; Methylamines; Ovalbumin; Protein Biosynthesis; T-Lymphocytes | 1991 |
Pasteurella multocida toxin, a potent mitogen, increases inositol 1,4,5-trisphosphate and mobilizes Ca2+ in Swiss 3T3 cells.
Topics: Ammonium Chloride; Animals; Bacterial Proteins; Bacterial Toxins; Bombesin; Calcium; Cells, Cultured; Chloroquine; Chromatography, High Pressure Liquid; Inositol 1,4,5-Trisphosphate; Methylamines; Mice; Mitogens; Pasteurella; Recombinant Proteins | 1991 |
The in vitro effects of various lysosomotropic agents on the gut of Schistosoma mansoni schistosomula.
Topics: Acridine Orange; Alanine; Amino Acids; Ammonium Chloride; Animals; Chloroquine; Dipeptides; Esters; Hydrogen-Ion Concentration; Leucine; Microscopy, Electron; Microscopy, Fluorescence; Schistosoma mansoni; Tryptophan | 1991 |
Lysosomal hydrolysis of lipids in a cell culture model of smooth muscle foam cells.
Topics: Ammonium Chloride; Animals; Aorta; Cells, Cultured; Chloroquine; Cholesterol Esters; Humans; Hydrolysis; Kinetics; Lipid Metabolism; Lipolysis; Lysosomes; Methylamines; Microscopy, Electron; Muscle, Smooth, Vascular; Rabbits; Skin; Triolein | 1991 |
Inhibition of duck hepatitis B virus infection by lysosomotropic agents.
Topics: Ammonium Chloride; Animals; Antiviral Agents; Cells, Cultured; Chloroquine; Ducks; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Lysosomes; Virus Replication | 1991 |
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens.
Topics: Adult; Ammonium Chloride; Chloroquine; Drug Resistance; Ferric Compounds; Humans; Hydrogen-Ion Concentration; Iron; Legionella; Monocytes; Nitrilotriacetic Acid; Transferrin | 1991 |
Effect of glycosylation inhibitors and acidotropic amines on the synthesis, processing, and intracellular-extracellular distribution of alpha-L-fucosidase in B-lymphoblastoid cells.
Topics: 1-Deoxynojirimycin; alpha-L-Fucosidase; Ammonium Chloride; B-Lymphocytes; Cells, Cultured; Chloroquine; Glucosamine; Glucosidases; Glycosylation; Humans; Mannosidases; Monensin; Tunicamycin | 1990 |
Acidotropic amines inhibit proteolytic processing of flavivirus prM protein.
Topics: Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; Flavivirus; Glycosylation; Methylamines; Mice; Protein Precursors; Viral Matrix Proteins | 1990 |
Rapid receptor-mediated catabolism of 125I-atrial natriuretic factor by vascular endothelial cells.
Topics: Ammonium Chloride; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Chloroquine; Dipeptides; Endothelium, Vascular; Iodine Radioisotopes; Monoiodotyrosine; Oligopeptides; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 1990 |
Kinetics of poliovirus uncoating in HeLa cells in a nonacidic environment.
Topics: Ammonium Chloride; Cell Transformation, Viral; Chloroquine; Endocytosis; Glutathione; HeLa Cells; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Methylamines; Monensin; Poliovirus; Tritium; Virus Replication | 1990 |
Initial events in bovine coronavirus infection: analysis through immunogold probes and lysosomotropic inhibitors.
Topics: Adsorption; Amantadine; Ammonium Chloride; Antigens, Viral; Chloroquine; Coronaviridae; Coronaviridae Infections; Endocytosis; Humans; Immunohistochemistry; Methylamines; Microscopy, Immunoelectron; Temperature; Time Factors; Tumor Cells, Cultured; Viral Plaque Assay | 1990 |
Evidence that the adenylate cyclase secreted from Bordetella pertussis does not enter animal cells by receptor-mediated endocytosis.
Topics: Adenylyl Cyclases; Ammonium Chloride; Animals; Biological Transport; Bordetella pertussis; Cell Line; Chloroquine; Endocytosis; Kinetics; Mice; Monensin; Neuroblastoma; Receptors, Cell Surface; Thermodynamics | 1990 |
Phylogeny of immune recognition: antigen processing/presentation in channel catfish immune responses to hemocyanins.
Topics: Ammonium Chloride; Animals; Antibody Formation; Antigen-Presenting Cells; Antigens; B-Lymphocytes; Chloroquine; Fixatives; Hemocyanins; Ictaluridae; In Vitro Techniques; Leupeptins; Lymphocyte Activation; Monensin; Monocytes; Phenylmethylsulfonyl Fluoride | 1990 |
Tubular lysosomes and their drug reactivity in cultured resident macrophages and in cell-free medium.
Topics: Ammonium Chloride; Animals; Cell-Free System; Cells, Cultured; Chloroquine; Colchicine; Culture Media; Female; Lysosomes; Macrophages; Mice; Microscopy, Fluorescence; Microtubules; Nocodazole; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of catabolism of radiolabeled antibodies by tumor cells using lysosomotropic amines and carboxylic ionophores.
Topics: Acid Phosphatase; Amantadine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Chloroquine; Chromatography, High Pressure Liquid; Humans; Iodine Radioisotopes; Lysosomes; Mice; Monensin; Nigericin; Temperature; Tumor Cells, Cultured; Verapamil | 1990 |
Cytotoxicity and effect of glycyl-D-phenylalanine-2-naphthylamide on lysosomes.
Topics: Acetylglucosaminidase; Ammonium Chloride; Animals; Cell Survival; Chloroquine; Dipeptides; Intracellular Membranes; Kinetics; Liver; Lysosomes; Male; Mitochondria, Liver; Nigericin; Rats; Rats, Inbred Strains; Vero Cells | 1990 |
Endocytosis of alpha 2-macroglobulin is developmentally regulated during myogenesis.
Topics: alpha-Macroglobulins; Ammonium Chloride; Animals; Antibodies, Monoclonal; Calcium; Cells, Cultured; Chloroquine; Endocytosis; Epitopes; Fluorescent Antibody Technique; Immunodiffusion; Microscopy, Electron; Microscopy, Phase-Contrast; Muscle Development; Rats | 1986 |
Acid intracellular vesicles and the cytolysis of mammalian target cells by Entamoeba histolytica trophozoites.
Topics: Adhesiveness; Ammonium Chloride; Animals; Cell Line; Cell Survival; Chloroquine; Cricetinae; Dextrans; Entamoeba histolytica; Female; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Phagocytosis; Primaquine | 1986 |
Interaction of insulin-like growth factor II with rat chondrocytes: receptor binding, internalization, and degradation.
Topics: Affinity Labels; Ammonium Chloride; Animals; Binding, Competitive; Cartilage; Cell Membrane; Cells, Cultured; Chloroquine; DNA; Insulin; Insulin-Like Growth Factor II; Kinetics; Photochemistry; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Somatomedin; RNA; Somatomedins; Temperature | 1987 |
Fibroblasts maintain a complete endocytic pathway in the presence of lysosomotropic amines.
Topics: Ammonium Chloride; Animals; beta-Galactosidase; beta-Glucosidase; beta-N-Acetylhexosaminidases; Cell Fractionation; Cell Line; Chloroquine; Dextrans; Endocytosis; Exocytosis; Fibroblasts; Fluorescein-5-isothiocyanate; Fluoresceins; Horseradish Peroxidase; Lysosomes | 1988 |
Role of acidic intracellular compartments in the biosynthesis of Dictyostelium lysosomal enzymes. The weak bases ammonium chloride and chloroquine differentially affect proteolytic processing and sorting.
Topics: Acetylglucosaminidase; alpha-Mannosidase; Ammonium Chloride; beta-Glucosidase; Biological Transport; Cell Fractionation; Centrifugation, Density Gradient; Chloroquine; Dictyostelium; Enzyme Precursors; Glucosidases; Golgi Apparatus; Hydrogen-Ion Concentration; Lysosomes; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Organelles; Peptide Hydrolases; Vacuoles | 1989 |
Obligatory role of macrophages in dengue virus antigen presentation to B lymphocytes.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Antigens, Viral; B-Lymphocytes; Chloroquine; Dengue Virus; Glutaral; Hot Temperature; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred Strains; Trypsin Inhibitor, Kunitz Soybean | 1989 |
Kinetic study of internalization and degradation of 131I-labeled follicle-stimulating hormone in mouse Sertoli cells and its relevance to other systems.
Topics: Ammonium Chloride; Animals; Cell Membrane; Cells, Cultured; Chloroquine; Follicle Stimulating Hormone; Hormones; Iodine Radioisotopes; Kinetics; Lysosomes; Male; Mathematics; Mice; Mice, Inbred C57BL; Models, Theoretical; Radioisotope Dilution Technique; Receptors, FSH; Sertoli Cells | 1989 |
Studies on the effect of lysosomotropic agents on the release of Gal beta 1-4GlcNAc alpha-2,6-sialytransferase from rat liver slices during the acute-phase response.
Topics: Acute-Phase Reaction; Ammonium Chloride; Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Chloroquine; Golgi Apparatus; Inflammation; Liver; Lysosomes; Methylamines; Orosomucoid; Rats; Sialyltransferases | 1989 |
Competition for antigen presentation in living cells involves exchange of peptides bound by class II MHC molecules.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Line; Chloroquine; Fixatives; Glutaral; Histocompatibility Antigens Class II; Hydrogen-Ion Concentration; Interleukin-2; Kinetics; Methylamines; Mice; Monensin; Muramidase; Peptides; Protein Binding; T-Lymphocytes; Temperature | 1989 |
Serum lipoprotein and Trypanosoma brucei brucei interactions in vitro.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Cholesterol; Chromatography, Thin Layer; Edetic Acid; Leukocytes; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Mice; Temperature; Trypanosoma brucei brucei | 1989 |
Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis.
Topics: Aminoquinolines; Ammonium Chloride; Bacterial Toxins; Calcium; Calcium Channels; Cell Line; Cell Membrane Permeability; Cell Survival; Chloroquine; Chromium Radioisotopes; DNA; Egtazic Acid; Hemolysin Proteins; Humans; Idoxuridine; Interleukin-2; Killer Cells, Natural; Membrane Glycoproteins; Membrane Proteins; Monensin; Neurotoxins; Perforin; Pore Forming Cytotoxic Proteins; Staphylococcus; Tumor Necrosis Factor-alpha | 1989 |
Effects of lysosomal inhibitors on 125I-insulin and 125I-asialofetuin degradation by the isolated, perfused rat liver and isolated rat hepatocytes.
Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoproteins; Chloroquine; Fetuins; In Vitro Techniques; Insulin; Iodine Radioisotopes; Leupeptins; Liver; Lysosomes; Male; Perfusion; Rats; Rats, Inbred Strains | 1985 |
The binary toxin produced by Clostridium botulinum enters cells by receptor-mediated endocytosis to exert its pharmacologic effects.
Topics: Adenosine Diphosphate Ribose; Ammonium Chloride; Autoradiography; Botulinum Toxins; Chloroquine; Endocytosis; Methylamines; Temperature; Tumor Cells, Cultured | 1989 |
Antigen processing by isolated rat intestinal villus enterocytes.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Cell Separation; Chloroquine; Intestinal Mucosa; Leupeptins; Lysosomes; Microvilli; Monensin; Ovalbumin; Rats | 1989 |
Solubilization of hydroxyapatite crystals by murine bone cells, macrophages and fibroblasts.
Topics: Ammonium Chloride; Animals; Bone and Bones; Calcium Phosphates; Chloroquine; Fibroblasts; Hydroxyapatites; In Vitro Techniques; Macrophages; Mice; Prostheses and Implants; Skin; Solubility | 1989 |
Interaction of Legionella pneumophila with tissue culture cells.
Topics: Ammonium Chloride; Cell Division; Chloroquine; Cycloheximide; HeLa Cells; Humans; Legionella | 1989 |
Hepatic processing of insulin. Characterization of differential inhibition by weak bases.
Topics: Ammonium Chloride; Animals; Cadaverine; Chloroquine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; In Vitro Techniques; Insulin; Iodine Radioisotopes; Kinetics; Liver; Methylamines; Perfusion; Rats; Subcellular Fractions | 1989 |
Endoproteolytic activation of Newcastle disease virus fusion proteins requires an intracellular acidic environment.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Hydrogen-Ion Concentration; Newcastle disease virus; Viral Fusion Proteins | 1989 |
The influence of pH on the vesicular traffic to the surface of the polarized epithelial cell, MDCK.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Dogs; Epithelium; Exocytosis; Hydrogen-Ion Concentration; Kidney; Membrane Glycoproteins; Monensin; Muramidase | 1989 |
Prevention of muscarinic acetylcholine receptor down-regulation by chloroquine: antilysosomal or antimuscarinic mechanisms.
Topics: Ammonium Chloride; Animals; Carbachol; Chloroquine; In Vitro Techniques; Lysosomes; Rats; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Requirements for histoplasmin presentation by accessory cells to a Histoplasma capsulatum-reactive T-cell line.
Topics: Ammonium Chloride; Animals; Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, Fungal; Azides; Cell Line; Cerulenin; Chloroquine; Deoxyglucose; Formaldehyde; Histoplasma; Histoplasmin; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Monensin; Phospholipases A; Phospholipases A2; Polymers; Protease Inhibitors; Sodium Azide; T-Lymphocytes; Temperature | 1989 |
Simian virus 40 infection is not mediated by lysosomal activation.
Topics: Ammonium Chloride; Cell Line; Cell Transformation, Viral; Chloroquine; Lysosomes; Simian virus 40; Virus Activation | 1987 |
Penetration and uncoating of rotaviruses in cultured cells.
Topics: Ammonium Chloride; Animals; Calcimycin; Calcium; Cell Line; Chloroquine; Endocytosis; Hydrogen-Ion Concentration; Lysosomes; Microscopy, Electron; Rotavirus; Swine; Temperature; Virus Replication | 1987 |
Evidence for endocytosis-independent infection by human rotavirus.
Topics: Amantadine; Ammonium Chloride; Animals; Cadaverine; Cell Line; Chloroquine; Cytochalasin B; Endocytosis; Haplorhini; Hydrogen-Ion Concentration; Lysosomes; Methylamines; Rotavirus; Vesicular stomatitis Indiana virus; Virus Replication | 1987 |
Biosynthesis and processing of lactoferrin in bone marrow cells, a comparison with processing of myeloperoxidase.
Topics: Ammonium Chloride; Biological Transport; Bone Marrow; Cell Compartmentation; Chloroquine; Cytoplasmic Granules; Glycosylation; Hexosaminidases; Humans; In Vitro Techniques; Lactoferrin; Lactoglobulins; Lysosomes; Molecular Weight; Monensin; Peroxidase; Protein Processing, Post-Translational | 1988 |
Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells.
Topics: Ammonium Chloride; Animals; Cell Line, Transformed; Cell Membrane; Chloroquine; Half-Life; Hexosaminidases; Immunosorbent Techniques; Molecular Weight; Oncogenes; Phosphorylation; Platelet-Derived Growth Factor; Protein Precursors; Rats; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Trypsin | 1988 |
Infectious rotavirus enters cells by direct cell membrane penetration, not by endocytosis.
Topics: Ammonium Chloride; Animals; Azides; Cell Line; Cell Membrane; Cell Membrane Permeability; Chloroquine; Dinitrophenols; Endocytosis; Hemagglutinins, Viral; Kinetics; Rotavirus; Sodium Azide; Trypsin | 1988 |
Differences in renal metabolism of insulin and cytochrome c.
Topics: Ammonium Chloride; Animals; Chloroquine; Cytochrome c Group; Glomerular Filtration Rate; In Vitro Techniques; Insulin; Kidney; Kinetics; Lysosomes; Male; Rats; Rats, Inbred Strains; Subcellular Fractions | 1988 |
Cytocidal mechanism of TNF: effects of lysosomal enzyme and hydroxyl radical inhibitors on cytotoxicity.
Topics: Ammonium Chloride; Animals; Chloroquine; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Leupeptins; Masoprocol; Methylamines; Mice; Muramidase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1988 |
Entry of poliovirus type 1 and Mouse Elberfeld (ME) virus into HEp-2 cells: receptor-mediated endocytosis and endosomal or lysosomal uncoating.
Topics: Ammonium Chloride; Cell Line; Chloroquine; Endocytosis; Endosomes; Hydrogen-Ion Concentration; Lysosomes; Monensin; Picornaviridae; Poliovirus; RNA, Viral; Virus Replication | 1985 |
Receptor-bound somatostatin and epidermal growth factor are processed differently in GH4C1 rat pituitary cells.
Topics: Ammonium Chloride; Animals; Cell Compartmentation; Cell Line; Cell Membrane; Chloroquine; Cytosol; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Leupeptins; Lysosomes; Pituitary Neoplasms; Protein Binding; Rats; Receptors, Cell Surface; Receptors, Somatostatin; Somatostatin | 1986 |
Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin.
Topics: Adenylate Cyclase Toxin; Ammonium Chloride; Animals; Bacillus anthracis; Bordetella pertussis; Chloroquine; Cricetinae; Cricetulus; Cyclic AMP; Cytochalasin D; Cytochalasins; Endocytosis; Hydrogen-Ion Concentration; In Vitro Techniques; Virulence Factors, Bordetella | 1988 |
Release of the variant surface glycoprotein during differentiation of bloodstream to procyclic forms of Trypanosoma brucei.
Topics: Ammonium Chloride; Animals; Antigens, Protozoan; Cell Membrane; Chloroquine; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Membrane Proteins; Monensin; Photofluorography; Precipitin Tests; Tosyllysine Chloromethyl Ketone; Trypanosoma brucei brucei | 1989 |
Adsorptive endocytosis of lysosomal enzymes by human fibroblasts: presence of two different functional systems that deliver an acid hydrolase to lysosomes.
Topics: Ammonium Chloride; Animals; Cattle; Cells, Cultured; Chloroquine; Endocytosis; Fibroblasts; Glucuronidase; Glycoside Hydrolases; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Mannosephosphates | 1989 |
Early events in arenavirus replication are sensitive to lysosomotropic compounds.
Topics: Adsorption; Amantadine; Ammonium Chloride; Antiviral Agents; Arenaviridae; Chloroquine; Lassa virus; Monensin; Virus Replication | 1989 |
Ammonium chloride, methylamine and chloroquine reversibly inhibit antibody secretion by plasma cells.
Topics: Adenosine Triphosphate; Ammonium Chloride; Animals; Antibodies; Antibody Formation; Chloroquine; Horseradish Peroxidase; Kinetics; Lymph Nodes; Lymphocytes; Male; Methylamines; Microscopy, Electron; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1985 |
Is movement of mannose 6-phosphate-specific receptor triggered by binding of lysosomal enzymes?
Topics: Ammonium Chloride; Carrier Proteins; Cathepsin D; Cell Membrane; Cells, Cultured; Chloroquine; Cycloheximide; Humans; Intracellular Membranes; Lysosomes; Mannosephosphates; Monensin; Receptor, IGF Type 2 | 1987 |
Secretion heterogeneity of lysosomal enzymes in Tetrahymena pyriformis.
Topics: Acid Phosphatase; Age Factors; alpha-Mannosidase; Ammonium Chloride; Animals; Azides; beta-Galactosidase; beta-N-Acetylhexosaminidases; Cell Compartmentation; Chloroquine; Cycloheximide; Extracellular Space; Glucosidases; Lysosomes; Mannosidases; Sodium Azide; Starvation; Tetrahymena pyriformis | 1987 |
Facilitated internalization of neocarzinostatin and its lipophilic polymer conjugate, SMANCS, into cytosol in acidic pH.
Topics: Ammonium Chloride; Animals; Antibiotics, Antineoplastic; Cells, Cultured; Chloroquine; Cytosol; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Furans; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Maleic Anhydrides; Mice; Mice, Inbred BALB C; Polystyrenes; Protein Binding; Thiocyanates; Zinostatin | 1987 |
Inhibition by lysosomotropic amines of dog thyroid secretion in vitro.
Topics: Ammonium Chloride; Animals; Bucladesine; Carbachol; Chloroquine; Cytochalasin B; Dogs; In Vitro Techniques; Kinetics; Lysosomes; Microscopy, Electron, Scanning; Thyroid Gland; Thyrotropin; Time Factors | 1985 |
Mitogenesis induced by calcium-containing crystals. Role of intracellular dissolution.
Topics: Ammonium Chloride; Calcium; Calcium Chloride; Cells, Cultured; Chloroquine; Durapatite; Fibroblasts; Humans; Hydroxyapatites; Male; Mitosis; Phosphates; Solubility; Spectrophotometry, Infrared; Thymidine | 1985 |
Studies on the mechanism of acute inhibition of thyroglobulin hydrolysis by iodine.
Topics: Ammonium Chloride; Animals; Bucladesine; Cells, Cultured; Chloroquine; Cycloheximide; Dactinomycin; Female; Hydrolysis; Iodine; Methimazole; Mice; Sodium Iodide; Thyroglobulin; Thyroid Gland; Time Factors | 1985 |
Modification of interactions between neutrophils and staphylococci by lysosomotropic weak bases.
Topics: Ammonium Chloride; Chloroquine; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Neutrophils; Phagocytosis; Staphylococcus aureus; Superoxides; Time Factors | 1985 |
Inhibition of herpes simplex virus type 1-induced interferon synthesis by monoclonal antibodies against viral glycoprotein D and by lysosomotropic drugs.
Topics: Ammonium Chloride; Antibodies, Monoclonal; Antibodies, Viral; Antigens, Viral; Cell Membrane; Chloroquine; Herpes Simplex; Humans; Hydrogen-Ion Concentration; Interferon Type I; Lysosomes; Simplexvirus; Viral Envelope Proteins; Viral Proteins | 1985 |
Inhibition of neutrophil oxidative metabolism by lysosomotropic weak bases.
Topics: Ammonium Chloride; Chloroquine; Clindamycin; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Methylamines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Interaction of insulin-like growth factor I/somatomedin-C with cultured rat chondrocytes: receptor binding and internalization.
Topics: Ammonium Chloride; Animals; Azides; Cadaverine; Cartilage; Chloroquine; Cross-Linking Reagents; Insulin; Insulin-Like Growth Factor I; Lysosomes; Photolysis; Rats; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Time Factors | 1986 |
The processing and intracellular transport of myeloperoxidase. Modulation by lysosomotropic agents and monensin.
Topics: Ammonium Chloride; Biological Transport, Active; Body Fluids; Cell Line; Chloroquine; Furans; Humans; Intracellular Fluid; Lysosomes; Molecular Weight; Monensin; Oligosaccharides; Peroxidase; Phosphorylation | 1986 |
Processing of a newly identified intermediate of human myeloperoxidase in isolated granules occurs at neutral pH.
Topics: Ammonium Chloride; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chloroquine; Cytoplasmic Granules; Hexosaminidases; Humans; Hydrogen-Ion Concentration; Ionophores; Leukemia, Myeloid, Acute; Molecular Weight; Monensin; Peroxidase; Protein Processing, Post-Translational | 1986 |
Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis.
Topics: Ammonium Chloride; Animals; Autoradiography; Azides; Botulinum Toxins; Calcium; Chloroquine; Electric Stimulation; Endocytosis; In Vitro Techniques; Lysosomes; Methylamines; Mice; Microscopy, Electron; Motor Neurons; Nerve Endings; Receptors, Cell Surface; Temperature; Tetanus Toxin | 1986 |
Binding and receptor-mediated endocytosis of erythropoietin in Friend virus-infected erythroid cells.
Topics: Ammonium Chloride; Animals; Cell Line; Cell Transformation, Neoplastic; Chloroquine; Endocytosis; Erythropoiesis; Erythropoietin; Friend murine leukemia virus; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mice, Inbred Strains; Receptors, Cell Surface; Receptors, Erythropoietin | 1987 |
Effect of lysosomotropic compounds on early events in foot-and-mouth disease virus replication.
Topics: Ammonium Chloride; Animals; Aphthovirus; Cattle; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Lysosomes; Monensin; Species Specificity; Virus Replication | 1987 |
On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.
Topics: Ammonium Chloride; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Chloroquine; Fibroblasts; Humans; Kinetics; Liver Neoplasms; Lysosomes; Monensin; Primaquine; Protein Processing, Post-Translational; Skin | 1987 |
Differential requirements for the processing and presentation of soluble and particulate bacterial antigens by macrophages.
Topics: Ammonium Chloride; Animals; Antigen-Presenting Cells; Antigens, Bacterial; Chloroquine; Female; Fixatives; Glutaral; Histocompatibility Antigens Class II; Hybridomas; Kinetics; Listeria monocytogenes; Macrophages; Mice; Mice, Inbred A; Mice, Inbred C57BL; Solubility; T-Lymphocytes | 1987 |
Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes.
Topics: Alkaloids; Ammonium Chloride; Animals; Cathepsin B; Cathepsin H; Cathepsins; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Kinetics; Liver; Lysosomes; Male; Monensin; Rats; Rats, Inbred Strains; Swainsonine; Tunicamycin | 1988 |
Transferrin endocytosis and iron uptake in developing myogenic cells in culture: effects of microtubular and metabolic inhibitors, sulphydryl reagents and lysosomotrophic agents.
Topics: 2,4-Dinitrophenol; Ammonium Chloride; Animals; Antimycin A; Azides; Cells, Cultured; Chick Embryo; Chloroquine; Colchicine; Dinitrophenols; Endocytosis; Iron; Methylamines; Muscles; Podophyllotoxin; Sodium Azide; Sulfhydryl Reagents; Transferrin; Vinblastine | 1988 |
Properties of binding sites for chloroquine in liver lysosomal membranes.
Topics: Ammonium Chloride; Animals; Cations, Divalent; Chloroquine; Detergents; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Lysosomes; Male; Mice; Neuraminidase; Osmolar Concentration; Phospholipases | 1988 |
Mediation of reduction of spontaneous and experimental pulmonary metastases by ricin A-chain immunotoxin 45-2D9-RTA with potentiation by systemic monensin in mice.
Topics: Ammonium Chloride; Animals; Antigens, Neoplasm; Chloroquine; Dimethyl Sulfoxide; Drug Synergism; Female; Immunotoxins; Lung Neoplasms; Mice; Mice, Inbred BALB C; Monensin; Ricin | 1988 |
Processing requirements for T cell activation by Mycoplasma arthritidis-derived mitogen.
Topics: Ammonium Chloride; Antigen-Presenting Cells; Chloroquine; Formaldehyde; Leupeptins; Lymphocyte Activation; Lysosomes; Macrophages; Mitogens; Monensin; Mycoplasma; Polymers; T-Lymphocytes | 1988 |
A comparative study on the effect of chloroquine and ammonium chloride on feeding process of Plasmodium falciparum in vitro.
Topics: Ammonium Chloride; Animals; Chloroquine; Hydrogen-Ion Concentration; Microscopy, Electron; Plasmodium falciparum; Vacuoles | 1987 |
Inhibition of hemoglobin degradation in Plasmodium falciparum by chloroquine and ammonium chloride.
Topics: Ammonium Chloride; Animals; Chloroquine; Digestion; Electrophoresis, Polyacrylamide Gel; Hemin; Hemoglobins; Plasmodium falciparum | 1987 |
Post-translational processing of the murine third component of complement.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Complement C3; Glycosylation; Humans; Macrophages; Mice; Monensin; Protein Precursors; Protein Processing, Post-Translational; Valinomycin | 1988 |
Effect of ammonium chloride on the multiplication of infectious pancreatic necrosis virus.
Topics: Ammonium Chloride; Chloroquine; Depression, Chemical; RNA Viruses; RNA, Viral; Time Factors; Virus Replication | 1988 |
Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles.
Topics: Ammonium Chloride; Animals; Binding, Competitive; Carrier Proteins; Cell Line; Cell Membrane; Chloroquine; Chromatography, Gel; Chromatography, High Pressure Liquid; Cytoplasm; Epithelium; Folate Receptors, GPI-Anchored; Folic Acid; Kinetics; Monensin; Receptors, Cell Surface; Tetrahydrofolates; Tritium | 1988 |
Electron microscopic evidence for stimulation of melanosomal maturation by lysosomotropic agents and monensin in cultured B16 mouse melanoma cells.
Topics: Ammonium Chloride; Animals; Cell Division; Cell Line; Chloroquine; Cytoplasmic Granules; Lysosomes; Melanocytes; Melanoma, Experimental; Mice; Microscopy, Electron; Monensin | 1987 |
Digestion of the host erythrocyte by malaria parasites is the primary target for quinoline-containing antimalarials.
Topics: Amino Acids; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Erythrocytes; Host-Parasite Interactions; Humans; Mefloquine; Methylamines; Plasmodium falciparum; Quinine; Quinolines; Vacuoles | 1986 |
Internalization and recycling of 125I-photoreactive insulin-receptor complexes in hepatocytes in primary culture.
Topics: Ammonium Chloride; Animals; Biological Transport; Cells, Cultured; Chloroquine; Cytoplasmic Granules; Endocytosis; Exocytosis; Insulin; Liver; Lysosomes; Male; Photochemistry; Rats; Receptor, Insulin | 1986 |
Degradation of dipalmitoyl phosphatidylcholine by isolated rat granular pneumocytes and reutilization for surfactant synthesis.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Ammonium Chloride; Animals; Chloroquine; Choline; Liposomes; Lung; Methylamines; Organoids; Pulmonary Surfactants; Quinacrine; Rats | 1987 |
Effects of various basic compounds on the degradation of formaldehyde-treated 125I-labeled bovine serum albumin in mouse liver lysosomes.
Topics: Acid Phosphatase; Ammonium Chloride; Animals; Chloroquine; Dose-Response Relationship, Drug; Formaldehyde; Hydrogen-Ion Concentration; Injections, Intravenous; Liver; Lysosomes; Mice; Protein Denaturation; Serum Albumin, Bovine; Time Factors; Vinblastine | 1987 |
Cerulenin is a potent inhibitor of antigen processing by antigen-presenting cells.
Topics: Ammonium Chloride; Animals; Antifungal Agents; Antigen-Presenting Cells; Antigens; Cell Line; Cerulenin; Chloroquine; Depression, Chemical; Lymphocyte Activation; Mice; Monensin | 1987 |
Monensin stimulation of arylsulfatase B activity in human chondrocytes.
Topics: Aged; Ammonium Chloride; Cartilage, Articular; Cell Count; Cells, Cultured; Chloroquine; Chondro-4-Sulfatase; Dose-Response Relationship, Drug; Female; Furans; Humans; Lysosomes; Male; Middle Aged; Monensin; Osteoarthritis; Sulfatases | 1986 |
The sequential transfer of internalized, cell surface sialoglycoconjugates through the lysosomes and Golgi complex in HeLa cells.
Topics: Ammonium Chloride; Borohydrides; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Chloroquine; Endocytosis; Golgi Apparatus; HeLa Cells; Humans; Lysosomes; Models, Biological; Sialoglycoproteins; Tritium | 1986 |
Responses of cultured cardiac myocytes to lysosomotropic compounds and methylated amino acids.
Topics: Ammonium Chloride; Animals; Cell Membrane Permeability; Cells, Cultured; Chloroquine; Leucine; Lysosomes; Methionine; Methylamines; Microscopy, Electron; Myocardium; Rats; Rats, Inbred Strains | 1985 |
Susceptibility of human malaria parasites to chloroquine is pH dependent.
Topics: Ammonium Chloride; Cells, Cultured; Chloroquine; Drug Resistance, Microbial; Erythrocytes; Humans; Malaria; Methylamines; Plasmodium falciparum | 1985 |
Insulin binding and degradation in isolated hepatocytes from streptozotocin injected rats.
Topics: Ammonium Chloride; Animals; Chloroquine; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Kinetics; Liver; Male; Rats; Rats, Inbred WF; Receptor, Insulin | 1985 |
Effects of lysosomotropic agents on lipogenesis.
Topics: Acetates; Ammonium Chloride; Cells, Cultured; Chloroquine; Choline; Cycloheximide; Fibroblasts; Humans; Hydrogen-Ion Concentration; Lipids; Lysosomes; Palmitates; Pyruvates; Quinine; Water | 1986 |
Effect of monensin on myoblast fusion.
Topics: Ammonium Chloride; Animals; Cell Fusion; Chick Embryo; Chloroquine; Furans; Mannose; Monensin; Muscles; Pronase | 1985 |
Uptake and processing of liposomal phospholipids by Kupffer cells in vitro.
Topics: Ammonium Chloride; Cells, Cultured; Chemical Phenomena; Chemistry; Chloroquine; In Vitro Techniques; Kupffer Cells; Liposomes; Lysophosphatidylcholines; Membrane Lipids; Phosphatidylcholines; Phospholipids | 1985 |
The mechanism of iron uptake by the rat placenta.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; DNA; Female; Hydrogen-Ion Concentration; Iron; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Temperature; Time Factors; Transferrin | 1985 |
Modification of membrane permeability during Semliki Forest virus infection.
Topics: Ammonium Chloride; Animals; Azides; Cell Membrane Permeability; Chloroquine; Deoxyglucose; Endoribonucleases; Fungal Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hygromycin B; Interferon Type I; Potassium; Protein Biosynthesis; Rubidium; Semliki forest virus; Sodium Azide; Virus Replication | 1985 |
The fate of the surface protein gp70 during entry of retrovirus into mouse fibroblasts.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glucosamine; Kinetics; Leucine; Leupeptins; Mice; Retroviridae; Retroviridae Proteins; Tritium; Viral Envelope Proteins | 1985 |
Kinetics of acid efflux from chloroplasts following the acid-base transition.
Topics: Acids; Adenosine Triphosphate; Ammonium Chloride; Buffers; Chloroplasts; Chloroquine; Chlorpromazine; Diffusion; Electrodes; Glass; Glutamates; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Nitriles; Phenylhydrazines; Plant Cells; Succinates; Surface-Active Agents; Temperature; Time Factors; Uncoupling Agents | 1971 |
Inhibition of multiplication of herpes simplex virus type 1 by ammonium chloride and chloroquine.
Topics: Ammonium Chloride; Cells, Cultured; Chloroquine; Humans; Hydrogen-Ion Concentration; Lysosomes; Simplexvirus; Virus Replication | 1984 |
Renal hydrolysis of absorbed protein: influence of load and lysosomal pH.
Topics: Absorption; Ammonium Chloride; Animals; Carbon Radioisotopes; Chloroquine; Cytochrome c Group; Horses; Hydrogen-Ion Concentration; Hydrolysis; Kidney; Kinetics; Lysosomes; Male; Rats; Rats, Inbred Strains | 1984 |
Processing of acetylated human low-density lipoprotein by parenchymal and non-parenchymal liver cells. Involvement of calmodulin?
Topics: Ammonium Chloride; Animals; Antipsychotic Agents; Calcium; Calcium-Binding Proteins; Calmodulin; Chloroquine; Humans; In Vitro Techniques; Lipoproteins, LDL; Liver; Rats; Tissue Distribution; Trifluoperazine | 1982 |
The effect of lysosomotrophic bases and inhibitors of transglutaminase on iron uptake by immature erythroid cells.
Topics: Acyltransferases; Adenosine Triphosphate; Ammonium Chloride; Animals; Chloroquine; Erythroblasts; Erythrocytes; Female; Iron; Liver; Microscopy, Electron; Microscopy, Fluorescence; Pregnancy; Rabbits; Rats; Reticulocytes; Transferrin; Transglutaminases | 1983 |
The kinetics of transferrin endocytosis and iron uptake from transferrin in rabbit reticulocytes.
Topics: Acyltransferases; Ammonium Chloride; Animals; Chloroquine; Cycloheximide; Endocytosis; Iron; Kinetics; Rabbits; Reticulocytes; Temperature; Transferrin; Transglutaminases | 1983 |
Ammonium chloride and chloroquine inhibit rabies virus infection in neuroblastoma cells. Brief report.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Endocytosis; Endosomes; Lysosomes; Mice; Neuroblastoma; Neurons; Rabies virus; Virus Replication | 1984 |
Effect of various lysosomotropic agents and microtubule disrupting drugs on the lactogenic and the mammogenic action of prolactin.
Topics: Ammonium Chloride; Animals; Caseins; Chloroquine; Culture Techniques; DNA; Female; Lactose Synthase; Lysosomes; Mammary Glands, Animal; Methylamines; Microtubules; Pregnancy; Prolactin; Rabbits; RNA | 1980 |
Metabolism of asialoglycoproteins in cultured rat hepatocytes: evidence for receptor mediated uptake and degradation which is not feed-back regulated.
Topics: alpha-Fetoproteins; Ammonium Chloride; Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Chloroquine; Cycloheximide; Fetuins; Leupeptins; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface | 1983 |
Action of lysosomotropic amines on spontaneous and interferon enhanced NK and CTL cytolysis.
Topics: Adult; Amines; Ammonium Chloride; Cadaverine; Chloroquine; Cytotoxicity, Immunologic; Depression, Chemical; Dose-Response Relationship, Drug; Humans; Interferons; Killer Cells, Natural; Lysosomes; Methylamines; T-Lymphocytes, Cytotoxic | 1984 |
The effect of cis-4-hydroxy-L-proline on intracellular degradation of newly synthesized collagen by freshly isolated chick tendon fibroblasts.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chick Embryo; Chloroquine; Collagen; Fibroblasts; Hydroxyproline; Lysosomes; Tendons | 1982 |
Effects of lysomotropic agents, and of microfilament- and microtubule-disrupting drugs on the activation of casein-gene expression by prolactin in the mammary gland.
Topics: Ammonium Chloride; Animals; Caseins; Chloroquine; Colchicine; Cytochalasin B; Cytoskeleton; Female; Lysosomes; Mammary Glands, Animal; Microtubules; Organ Culture Techniques; Prolactin; Rabbits; Receptors, Cell Surface; RNA, Messenger | 1980 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cycloheximide; Dactinomycin; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Liver Neoplasms; Ornithine Decarboxylase; Peptides; Receptors, Cell Surface | 1981 |
Inactivation by chloroquine of alpha-galactosidase in cultured human skin fibroblasts.
Topics: alpha-Galactosidase; Ammonium Chloride; Cells, Cultured; Chloroquine; Culture Media; Cycloheximide; Dose-Response Relationship, Drug; Fibroblasts; Galactosidases; Glucuronidase; Hexosaminidases; Humans | 1981 |
Mannose-specific endocytosis receptor of alveolar macrophages: demonstration of two functionally distinct intracellular pools of receptor and their roles in receptor recycling.
Topics: Ammonium Chloride; Animals; Cell Membrane; Chloroquine; Endocytosis; Female; Formaldehyde; Glycoproteins; Hydrogen-Ion Concentration; Intracellular Membranes; Lectins, C-Type; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Membrane Glycoproteins; Membrane Proteins; Polymers; Pulmonary Alveoli; Rats; Receptors, Cell Surface; Trypsin | 1982 |
[Short-term effect of prolactin on its receptor].
Topics: Ammonium Chloride; Animals; Chloroquine; Female; Lactation; Pregnancy; Prolactin; Rabbits; Receptors, Cell Surface; Receptors, Prolactin; Time Factors | 1980 |
The uncoating of paramyxoviruses may not require a low pH mediated step.
Topics: Ammonium Chloride; Animals; Chloroquine; Cricetinae; Hydrogen-Ion Concentration; Influenza A virus; Newcastle disease virus; Parainfluenza Virus 1, Human; Paramyxoviridae; Time Factors; Transcription, Genetic; Vesicular stomatitis Indiana virus; Virus Cultivation | 1983 |
Entry of mouse hepatitis virus 3 into cells.
Topics: Ammonium Chloride; Animals; Chloroquine; Cytopathogenic Effect, Viral; Hepatitis, Viral, Animal; L Cells; Lysosomes; Mice; Murine hepatitis virus; Virus Replication | 1984 |
Effect of lysosomotropic agents on the foot-and-mouth disease virus replication.
Topics: Ammonium Chloride; Animals; Aphthovirus; Cell Line; Chloroquine; Cricetinae; DNA Replication; Kidney; Kinetics; Lysosomes; Transcription, Genetic; Virus Replication | 1984 |
Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate.
Topics: Adenoviruses, Human; Amines; Ammonium Chloride; Carcinoma; Cell Line; Chloroquine; Drug Synergism; Epidermal Growth Factor; Exotoxins; Humans; Hydrogen-Ion Concentration; Kinetics; Methylamines; Monensin; Mouth Neoplasms; Protein Biosynthesis; Pseudomonas; Receptors, Virus | 1984 |
Antigen conformation determines processing requirements for T-cell activation.
Topics: Ammonium Chloride; Animals; Antigens; Chloroquine; Clone Cells; Leupeptins; Lymphocyte Activation; Lysosomes; Mice; Monensin; Myoglobin; Peptide Fragments; Protein Conformation; Protein Denaturation; Structure-Activity Relationship; T-Lymphocytes | 1984 |
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine.
Topics: Ammonium Chloride; Animals; Chloroquine; Endocytosis; Erythrocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Malaria; Methylamines; Monensin; Plasmodium falciparum | 1984 |
Endocytosis of liposomes and intracellular fate of encapsulated molecules: encounter with a low pH compartment after internalization in coated vesicles.
Topics: Ammonium Chloride; Animals; Cell Line; Chemical Phenomena; Chemistry, Physical; Chlorocebus aethiops; Chloroquine; Coated Pits, Cell-Membrane; Colloids; Endocytosis; Fluorescent Dyes; Glycerol; Gold; Hydrogen-Ion Concentration; Kidney; Liposomes; Mice; Organoids; Vacuoles | 1983 |
Stimulation of tyrosinase activity of cultured melanoma cells by lysosomotropic agents.
Topics: Ammonium Chloride; Animals; Catechol Oxidase; Cell Line; Chloroquine; Cycloheximide; Ethylamines; Hydrogen-Ion Concentration; Imidazoles; Melanins; Melanoma; Methylamines; Mice; Monophenol Monooxygenase | 1983 |
Mechanism of rabies virus entry into CER cells.
Topics: Adsorption; Ammonium Chloride; Animals; Cell Membrane; Cells, Cultured; Chick Embryo; Chloroquine; Coated Pits, Cell-Membrane; Deoxyglucose; Endocytosis; Lipase; Lysosomes; Microscopy, Electron; Microvilli; Neuraminidase; Organoids; Peptide Hydrolases; Rabies virus; Vacuoles | 1984 |
Mechanism of autodegradation of cell-surface macromolecules shed by human melanoma cells.
Topics: Ammonium Chloride; Biological Transport; Cadaverine; Cell Line; Chloroquine; Coated Pits, Cell-Membrane; Colchicine; Cytochalasin B; Endocytosis; Humans; Leupeptins; Lysosomes; Melanoma; Membrane Proteins; Monensin; Neoplasm Proteins; Time Factors; Tunicamycin | 1984 |
Primary amines and chloroquine inhibit cytotoxic responses to Shigella toxin and permit late antibody rescue of toxin treated cells.
Topics: Amines; Ammonium Chloride; Bacterial Toxins; Boric Acids; Cell Membrane Permeability; Cell Survival; Chloroquine; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; HeLa Cells; Humans; Serine; Shiga Toxins | 1984 |
Stimulation of the release of lysosomal and nonlysosomal granular enzymes from macrophages treated with monensin.
Topics: Acid Phosphatase; alpha-Glucosidases; Ammonium Chloride; Animals; beta-Galactosidase; beta-Glucosidase; Chloroquine; Furans; Galactosyltransferases; Glucuronidase; Golgi Apparatus; Hexosaminidases; Hydrogen-Ion Concentration; Lysosomes; Macrophages; Mice; Monensin; Solubility | 1984 |
Cultured human monocytes and fibroblasts solubilize calcium phosphate crystals.
Topics: Ammonium Chloride; Calcium Phosphates; Cells, Cultured; Chloroquine; Crystallization; Fibroblasts; Humans; Lymphocytes; Monocytes; Skin; Solubility; Thymidine | 1984 |
Degradation of surface-labeled hepatoma membrane polypeptides: effect of inhibitors.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Iodine Radioisotopes; Liver Neoplasms, Experimental; Lysosomes; Membrane Proteins; Monensin; Neoplasm Proteins; Peptides; Protease Inhibitors; Rats; Temperature | 1984 |
Effects of lysosomotropic weak bases on infection of BHK-21 cells by Sindbis virus.
Topics: Amantadine; Ammonium Chloride; Animals; Cell Line; Chloroquine; Cricetinae; Endocytosis; Kidney; Lysosomes; RNA, Viral; Sindbis Virus; Virus Replication | 1984 |
15-Hydroxyprostaglandin dehydrogenase activity in human fetal kidney tissue.
Topics: Ammonium Chloride; Chemical Fractionation; Chloroquine; Cytosol; Fetus; Humans; Hydroxyprostaglandin Dehydrogenases; Kidney; Kidney Medulla; Leucine; Organ Culture Techniques; Time Factors | 1984 |
Methylated amino acids and lysosomal function in cultured heart cells.
Topics: Ammonium Chloride; Animals; Cathepsin B; Cathepsins; Cells, Cultured; Chloroquine; Heart; Leucine; Lysosomes; Methionine; Myocardium; Proteins; Rats | 1984 |
Iron metabolism of established human hematopoietic cell lines in vitro.
Topics: Ammonium Chloride; Cell Line; Chloroquine; Endocytosis; Erythrocytes; Ferritins; Heme; Humans; Iron; Kinetics; Leukemia, Erythroblastic, Acute; Lymphocytes; Lymphoma; Macrophages; Transferrin | 1983 |
Inhibitory effect of NH4Cl on secretion of collagen in human gingival fibroblasts.
Topics: Ammonium Chloride; Cells, Cultured; Chloroquine; Collagen; Dose-Response Relationship, Drug; Fibroblasts; Fibronectins; Gingiva; Humans; Methylamines; Time Factors | 1984 |
Antigen presentation by human monocytes: evidence for stimulant processing and requirement for interleukin 1.
Topics: Ammonium Chloride; Animals; Antigens; Bacterial Proteins; Chloroquine; Female; Formaldehyde; Interleukin-1; Lymphocyte Activation; Lymphocyte Cooperation; Lysosomes; Mice; Mice, Inbred C3H; Monocytes; Polymers; Staphylococcal Protein A; Streptolysins; T-Lymphocytes | 1983 |
Isolation of chloroquine-resistant Chinese hamster V79 cell variants that are also resistant to ammonium chloride.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Leupeptins; Lysosomes; Mutation; Phenotype; Proteins | 1983 |
Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro.
Topics: Albumins; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Endocytosis; Female; Hydrogen-Ion Concentration; Kupffer Cells; Liposomes; Lysosomes; Phospholipids; Proteins; Rats; Temperature | 1984 |
Binding and degradation of [125I]human growth hormone in rat adipocytes.
Topics: Adipose Tissue; Ammonium Chloride; Animals; Chloroquine; Colchicine; Growth Hormone; Humans; Iodine Radioisotopes; Leupeptins; Rats; Rats, Inbred Strains; Temperature; Time Factors | 1984 |
Intravesicular pH and iron uptake by immature erythroid cells.
Topics: Ammonium Chloride; Animals; Bicarbonates; Chloroquine; Dimethadione; Fluorescein; Fluoresceins; Hydrogen-Ion Concentration; Iron; Liver; Methylamines; Microscopy, Fluorescence; Organoids; Oxalates; Oxalic Acid; Rabbits; Rats; Reticulocytes; Transferrin | 1984 |
A cytochemical study of GERL in cultured human fibroblasts.
Topics: Acid Phosphatase; Ammonium Chloride; Cells, Cultured; Centrioles; Chloroquine; Fibroblasts; Golgi Apparatus; Humans; Lipids; Lysosomes; Mitosis; Mucolipidoses; Mucopolysaccharidoses; Organoids | 1981 |
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.
Topics: Ammonium Chloride; Animals; Antigens, Surface; Chloroquine; Immunity, Cellular; Listeria monocytogenes; Macrophages; Mice; T-Lymphocytes | 1982 |
Degradation of microinjected proteins: effects of lysosomotropic agents and inhibitors of autophagy.
Topics: Ammonium Chloride; Autophagy; Benzimidazoles; Cell Line; Cell Nucleus; Chloroquine; Demecolcine; Humans; L-Lactate Dehydrogenase; Lysosomes; Microinjections; Nocodazole; Phagocytosis; Protein Biosynthesis; Proteins; Pyruvate Kinase; Serum Albumin, Bovine | 1983 |
Insulin degradation by hepatocytes in primary culture.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Insulin; Iodine Radioisotopes; Kinetics; Liver; Male; Rats | 1981 |
Inhibition of myoblast fusion by lysosomotropic amines.
Topics: Ammonium Chloride; Animals; Cell Fusion; Cells, Cultured; Chick Embryo; Chloroquine; Creatine Kinase; Dose-Response Relationship, Drug; Isoenzymes; Kinetics; Methylamines; Muscles | 1982 |
Lysosomotropic agents ammonium chloride and chloroquine inhibit both the synthesis and secretion of procollagen by freshly isolated embryonic chick tendon cells.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chick Embryo; Chloroquine; Fibroblasts; Lysosomes; Procollagen; Tendons | 1982 |
Inhibition of Semliki forest virus penetration by lysosomotropic weak bases.
Topics: Amantadine; Ammonium Chloride; Animals; Butylamines; Cell Fusion; Cell Line; Chloroquine; Cricetinae; Endocytosis; Lysosomes; Mesocricetus; Methylamines; Receptors, Virus; RNA, Viral; Semliki forest virus | 1982 |
Studies on the mechanism of phospholipid storage induced by amantadine and chloroquine in Madin Darby canine kidney cells.
Topics: Amantadine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Dogs; Kidney; Liver; Lysosomes; Phospholipases A; Phospholipids; Subcellular Fractions; Type C Phospholipases | 1982 |
Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.
Topics: Ammonium Chloride; Chloroquine; Fibroblasts; Glucuronidase; Hexosaminidases; Humans; Hydrogen-Ion Concentration; Lysosomes; Mucolipidoses; Pinocytosis; Receptors, Drug | 1980 |
Degradation of apolipoprotein B of low density lipoprotein by cultured bovine smooth muscle cells. Accumulation of intermediates in the presence of protease inhibitors.
Topics: Ammonium Chloride; Animals; Apolipoproteins; Apolipoproteins B; Cattle; Cells, Cultured; Chloroquine; Electrophoresis, Polyacrylamide Gel; Humans; Leupeptins; Lipoproteins, LDL; Muscle, Smooth, Vascular; Protease Inhibitors | 1981 |
Inhibition of cholera toxin activation of the adenylate cyclase system in intact HeLa cells.
Topics: Adenylyl Cyclases; Ammonium Chloride; Cadaverine; Chloroquine; Cholera Toxin; Enzyme Activation; G(M1) Ganglioside; HeLa Cells; Humans; Methylamines; Receptors, Cell Surface; Receptors, Immunologic | 1980 |
Is the receptor-mediated endocytosis of cholera toxin A pre-requisite for its activation of adenylate cyclase in intact rat hepatocytes?
Topics: Adenylyl Cyclases; Ammonium Chloride; Animals; Cadaverine; Chloroquine; Cholera Toxin; Endocytosis; Enzyme Activation; Liver; Lysosomes; Macromolecular Substances; Male; Methylamines; Rats; Receptors, Drug | 1981 |
Glucagon degradation in isolated rat hepatocytes: effect of ammonium chloride and chloroquine.
Topics: Ammonium Chloride; Animals; Chloroquine; Glucagon; Liver; Male; Rats; Rats, Inbred Strains | 1981 |
Action of weak bases on phagosomes of cultured macrophages. Suppression by ammonium ions of an early increase in phagosomal pH.
Topics: Ammonium Chloride; Animals; Ascitic Fluid; Cells, Cultured; Chloroquine; Hydrogen-Ion Concentration; Macrophages; Mice; Phagocytosis; Time Factors | 1981 |
Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: apparent inhibition of receptor recycling.
Topics: Ammonium Chloride; Animals; Chloroquine; Endocytosis; Kinetics; Macrophages; Mannose; Rats; Receptors, Drug; Serum Albumin; Temperature | 1980 |
Factors that influence the uptake of beta-hexosaminidase A by rat peritoneal macrophages.
Topics: Acetylglucosaminidase; Ammonium Chloride; Animals; Biological Transport; Chloroquine; Colchicine; Cytochalasin B; Female; Glycoproteins; Hexosaminidases; Humans; Kinetics; Macrophages; Methylamines; Phagocytosis; Placenta; Pregnancy; Quinacrine; Rats | 1980 |
The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.
Topics: Acetylation; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cholesterol Esters; Female; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Male; Mice; Progesterone; Tritium | 1980 |
Evidence that Sindbis virus infects BHK-21 cells via a lysosomal route.
Topics: Ammonium Chloride; Animals; Cell Line; Cell Transformation, Viral; Chloroquine; Cricetinae; Kidney; Kinetics; Lysosomes; Protein Biosynthesis; Sindbis Virus; Viral Proteins; Virus Replication | 1980 |
Diphtheria toxin entry into cells is facilitated by low pH.
Topics: Abrin; Ammonium Chloride; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; Chloroquine; Diphtheria Toxin; Endocytosis; Hydrogen-Ion Concentration; Lectins; Plant Lectins; Ribosome Inactivating Proteins, Type 2; Ricin | 1980 |
Cultured proximal cells derived from transgenic mouse provide a model to study drug toxicity.
Topics: Acetylglucosaminidase; Acid Phosphatase; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Gentamicins; Kidney Tubules, Proximal; Mice; Mice, Transgenic | 1995 |
Agonist-induced internalization of the substance P (NK1) receptor expressed in epithelial cells.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Arsenicals; Cell Line, Transformed; Chloroquine; Colchicine; Endocytosis; Epithelium; Hypertonic Solutions; Immune Sera; Immunohistochemistry; Kinetics; Leupeptins; Microscopy, Fluorescence; Molecular Sequence Data; Monensin; Peptides; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P; Time Factors; Transfection | 1994 |
Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II).
Topics: 2,2'-Dipyridyl; Ammonium Chloride; Azides; Biological Transport; Cell Line; Chloroquine; Cytoplasm; Endocytosis; Fluoresceins; Humans; Iron; Iron Chelating Agents; Kinetics; Leukemia, Erythroblastic, Acute; Monensin; Receptors, Transferrin; Transferrin; Tumor Cells, Cultured | 1995 |
Purification and characterization of a Shiga toxin A subunit-CD4 fusion protein cytotoxic to human immunodeficiency virus-infected cells.
Topics: Ammonium Chloride; Animals; Bacterial Toxins; Base Sequence; Brefeldin A; CD4 Antigens; Cell Compartmentation; Cell Line; Chlorocebus aethiops; Chloroquine; Cyclopentanes; Cytotoxins; DNA Primers; HIV Infections; Humans; In Vitro Techniques; Molecular Sequence Data; Recombinant Fusion Proteins; Shiga Toxins; Vero Cells | 1995 |
Differential roles of de novo sphingolipid biosynthesis and turnover in the "burst" of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Culture Media; Mice; Palmitic Acid; Palmitic Acids; Phosphatidylethanolamines; Serine; Sphingolipids; Sphingosine | 1995 |
Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr1 gene.
Topics: Acids; Ammonium Chloride; Animals; Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Cells, Cultured; Chloroquine; CHO Cells; Cricetinae; Gene Expression; Hydrogen-Ion Concentration; Lysosomes; Macrolides; Plasmodium falciparum; Proton-Translocating ATPases; Protozoan Proteins; Stereoisomerism; Transfection | 1994 |
Tilorone-induced lysosomal storage of sulphated glycosaminoglycans can be separated from tilorone-induced enhancement of lysosomal enzyme secretion.
Topics: Ammonium Chloride; Animals; beta-N-Acetylhexosaminidases; Cattle; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Fibroblasts; Glycosaminoglycans; Lysosomes; Mucopolysaccharidoses; Tilorone | 1995 |
Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein.
Topics: Alzheimer Disease; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Chloroquine; Endopeptidases; Enzyme Activation; Glycopeptides; Humans; Immunosorbent Techniques; Kinetics; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protease Inhibitors; Protein Kinase C; Tumor Cells, Cultured | 1995 |
Mechanism of lysis of Trypanosoma brucei gambiense by human serum.
Topics: Ammonium Chloride; Animals; Benzyl Alcohol; Benzyl Alcohols; Blood; Chloroquine; Complement System Proteins; Cytochalasins; Mice; Mice, Inbred C3H; Sulfates; Trypanosoma brucei gambiense; Variant Surface Glycoproteins, Trypanosoma; Vinblastine; Zinc Compounds; Zinc Sulfate | 1994 |
Characteristics of invasion of HEp-2 cells by Providencia alcalifaciens.
Topics: Adolescent; Adult; Ammonium Chloride; Cadaverine; Cell Line; Child; Child, Preschool; Chloroquine; Colchicine; Cytochalasin D; Diarrhea; Diarrhea, Infantile; Enterobacteriaceae Infections; Female; Humans; Immunosuppressive Agents; Infant; Male; Middle Aged; Providencia; Temperature; Time Factors | 1995 |
Monensin and brefeldin A inhibit high density lipoprotein-mediated cholesterol efflux from cholesterol-enriched cells. Implications for intracellular cholesterol transport.
Topics: Ammonium Chloride; Animals; Aorta, Abdominal; Biological Transport; Brefeldin A; Cells, Cultured; Chloroquine; Cholesterol; Cyclopentanes; Dose-Response Relationship, Drug; Fibroblasts; Humans; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Male; Models, Biological; Monensin; Muscle, Smooth, Vascular; Nigericin; Protein Synthesis Inhibitors; Skin; Sterols; Swine | 1995 |
Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes.
Topics: Acids; Ammonium Chloride; Animals; Chloroquine; Dose-Response Relationship, Drug; Endocytosis; Flagella; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Intracellular Membranes; Leupeptins; Lipoproteins, HDL; Microscopy, Immunoelectron; Models, Biological; Monensin; Organelles; Protein Binding; Trypanosoma brucei brucei | 1994 |
Receptor-mediated nuclear translocation of growth hormone.
Topics: Ammonium Chloride; Animals; Autoradiography; Biological Transport; Carrier Proteins; Cell Nucleus; Cells, Cultured; Chloroquine; DNA, Complementary; Endocytosis; Growth Hormone; Iodine Radioisotopes; Liver; Male; Molecular Weight; Rats; Receptors, Somatotropin; Transfection | 1994 |
alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells.
Topics: Ammonium Chloride; Azides; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Dose-Response Relationship, Drug; Fucose; Glycated Serum Albumin; Glycation End Products, Advanced; Hexoses; Humans; Iodine Radioisotopes; Kinetics; Liver Neoplasms; Receptors, Cell Surface; Serum Albumin; Sodium Azide; Sodium Fluoride; Stereoisomerism; Tissue Plasminogen Activator; Tumor Cells, Cultured | 1994 |
Giardiavirus enters Giardia lamblia WB trophozoite via endocytosis.
Topics: Ammonium Chloride; Animals; Azides; Cell Membrane; Chloroquine; Cytoplasm; Endocytosis; Giardia lamblia; Microscopy, Electron; Microscopy, Fluorescence; RNA, Viral; Sodium Azide; Vacuoles; Virus Physiological Phenomena; Viruses | 1993 |
Invariant chain retains MHC class II molecules in the endocytic pathway.
Topics: Ammonium Chloride; Animals; Antigens, Differentiation, B-Lymphocyte; Cell Line; Chloroquine; Endocytosis; Histocompatibility Antigens Class II; Leupeptins; Lysosomes; Primaquine | 1993 |
Inhibition of apolipoprotein E degradation in a post-Golgi compartment by a cysteine protease inhibitor.
Topics: Albumins; Ammonium Chloride; Animals; Apolipoproteins E; Brefeldin A; Calcium; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; CHO Cells; Cricetinae; Cyclopentanes; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Golgi Apparatus; Humans; Kinetics; Leupeptins; Molecular Sequence Data; Transfection; Tumor Cells, Cultured | 1993 |
Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.
Topics: 3T3 Cells; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cycloheximide; Endoplasmic Reticulum; Golgi Apparatus; Hexosaminidases; Leupeptins; Lysosomes; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Peptide Fragments; Receptors, Erythropoietin | 1993 |
Inhibition of beta A4 production by specific modulation of beta-secretase activity.
Topics: Ammonium Chloride; Amyloid; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Cells, Cultured; Chloroquine; Cloning, Molecular; Endopeptidases; Humans; Isoenzymes; Methylamines; Neuroblastoma; Prion Proteins; Prions; Protein Precursors; Transfection | 1995 |
Effect of pH on in vitro potency of amantadine against Plasmodium falciparum.
Topics: Adamantane; Amantadine; Ammonium Chloride; Animals; Antimalarials; Chloroquine; Culture Media; Dose-Response Relationship, Drug; Drug Resistance; Humans; Hydrogen-Ion Concentration; Mefloquine; Plasmodium falciparum; Quinine | 1996 |
A vacuolar-type proton ATPase mediates acidification of plasmalemmal vesicles during potocytosis.
Topics: Acids; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antimalarials; Biological Transport; Cell Compartmentation; Cell Line; Cell Membrane; Chloroquine; Enzyme Inhibitors; Epithelial Cells; Epithelium; Folic Acid; Haplorhini; Intracellular Membranes; Ionophores; Kidney; Macrolides; Monensin; Octoxynol; Oligomycins; Proton-Translocating ATPases; Protons; Tetrahydrofolates; Vacuoles | 1996 |
Biosynthesis and processing of proteinase 3 in U937 cells. Processing pathways are distinct from those of cathepsin G.
Topics: Amino Acid Sequence; Ammonium Chloride; Animals; Autoradiography; Brefeldin A; Cathepsin C; Cathepsin G; Cathepsins; Cell Line; Chloroquine; Cricetinae; Cyclopentanes; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Humans; Isoleucine; Methionine; Molecular Sequence Data; Myeloblastin; Neutrophils; Peptide Fragments; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Sequence Homology, Amino Acid; Serine Endopeptidases; Sulfur Radioisotopes; Tritium | 1996 |
Drug inhibition of the macrophage response to metal wear particles in vitro.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Cells, Cultured; Chloroquine; Chromium Compounds; Corrosion; Cytochalasin B; Dinoprostone; Hydrogen-Ion Concentration; Interleukin-6; Macrolides; Macrophages; Phagocytosis; Piroxicam; Rats; Titanium | 1996 |
Pathway of rubella virus infectious entry into Vero cells.
Topics: Ammonium Chloride; Animals; Chlorocebus aethiops; Chloroquine; Hydrogen-Ion Concentration; Methylamines; Monensin; Rubella virus; Transfection; Vero Cells | 1996 |
Factors regulating insulin-like growth factor-binding protein-3 binding, processing, and potentiation of insulin-like growth factor action.
Topics: Adenosine Triphosphate; Aminoisobutyric Acids; Ammonium Chloride; Animals; Binding, Competitive; Cattle; Cells, Cultured; Chloroquine; Cross-Linking Reagents; Drug Synergism; Fibroblasts; Glycosylation; Heparin; Humans; Hydrogen-Ion Concentration; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Iodine Radioisotopes; Recombinant Proteins | 1996 |
Adenovirus uncoating and nuclear establishment are not affected by weak base amines.
Topics: Adenoviridae; Amantadine; Ammonium Chloride; Chloroquine; HeLa Cells; Humans; Hydrogen-Ion Concentration; Methylamines; Transcription, Genetic; Virus Replication | 1996 |
Degradation of aggrecan precursors within a specialized subcompartment of the chicken chondrocyte endoplasmic reticulum.
Topics: Aggrecans; Ammonium Chloride; Animals; Azides; Calcium; Cartilage; Cells, Cultured; Chick Embryo; Chloroquine; Chondroitin Sulfate Proteoglycans; Cycloheximide; Cysteine Endopeptidases; Endoplasmic Reticulum, Smooth; Extracellular Matrix Proteins; Fluorescent Antibody Technique; Lectins, C-Type; Lysosomes; Oxidation-Reduction; Protease Inhibitors; Protein Precursors; Proteoglycans; Serine Endopeptidases; Sodium Azide; Temperature | 1996 |
Uptake and transport characteristics of chloroquine in an in-vitro cell culture system of the intestinal mucosa, Caco-2.
Topics: Ammonium Chloride; Antimalarials; Biological Transport; Caco-2 Cells; Chloroquine; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Temperature | 1996 |
Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.
Topics: Alkalies; Ammonium Chloride; Amyloid beta-Protein Precursor; Animals; Anti-Bacterial Agents; Base Sequence; Cell Line; Chloroquine; Cytosol; DNA, Complementary; Endocytosis; Endosomes; Enzyme Inhibitors; Humans; Hybridomas; Hydrogen-Ion Concentration; Lysosomes; Macrolides; Mice; Molecular Sequence Data; Plasmids; Proton-Translocating ATPases | 1996 |
Porcine reproductive and respiratory syndrome virus enters cells through a low pH-dependent endocytic pathway.
Topics: Actin Cytoskeleton; Ammonium Chloride; Animals; Anti-Bacterial Agents; Cell Line; Chloroquine; Endocytosis; Hydrogen-Ion Concentration; Macrolides; Porcine respiratory and reproductive syndrome virus; RNA; Swine; Virus Replication | 1996 |
Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine.
Topics: Adenosine Triphosphate; Ammonium Chloride; Amodiaquine; Animals; Anti-Bacterial Agents; Antimalarials; Biological Transport, Active; Chloroquine; Enzyme Inhibitors; Glucose; Hydrogen-Ion Concentration; Ionophores; Kinetics; Macrolides; Nigericin; Plasmodium falciparum; Proton-Translocating ATPases; Protons | 1996 |
Effect of astroglial cell swelling on pH of acidic intracellular compartments.
Topics: Acridine Orange; Ammonium Chloride; Animals; Astrocytes; Cell Size; Chloroquine; Dextrans; Extracellular Space; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Fluorometry; Glutamic Acid; Hydrogen-Ion Concentration; Hypotonic Solutions; Intracellular Fluid; Lysosomes; Mice; Osmolar Concentration; Rats | 1996 |
Receptor-mediated endocytosis of immunoglobulin light chains by renal proximal tubule cells.
Topics: Ammonium Chloride; Animals; Brefeldin A; Cattle; Cell Line; Cell Line, Transformed; Cells, Cultured; Chloroquine; Cyclopentanes; Endocytosis; Enzyme Inhibitors; Female; Humans; Hypertonic Solutions; Immunoglobulin Light Chains; Iodine Radioisotopes; Kidney Tubules, Proximal; Kinetics; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Simian virus 40; Sucrose; Temperature | 1997 |
Developmental down-regulation of receptor-mediated endocytosis of an insect lipoprotein.
Topics: Ammonium Chloride; Animals; Binding Sites; Carbocyanines; Carrier Proteins; Chloroquine; Down-Regulation; Endocytosis; Fat Body; Fluorescent Dyes; Food Deprivation; Grasshoppers; Hemolymph; Indicators and Reagents; Lipid Mobilization; Lipoproteins; Lipoproteins, HDL; Male; Molting; Receptors, Lipoprotein; Succinimides; Time Factors; Tritium | 1997 |
ATP-dependent lysis of isolated lysosomes by basic substances and acidic ionophores.
Topics: Adenosine Triphosphate; Ammonium Chloride; Aniline Compounds; Animals; Atropine; Butylamines; Chloroquine; Cytosol; Ethanolamines; Hydrogen-Ion Concentration; Ionophores; Lysosomes; Male; Methylamines; Osmolar Concentration; Rats; Rats, Wistar; Vacuoles | 1997 |
Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand.
Topics: Ammonium Chloride; Angiotensin II; Animals; Biological Transport; Calcium; Cell Membrane; Chloroquine; Endocytosis; Epitopes; Fluorescein; Fluoresceins; Fluorescent Antibody Technique, Direct; Humans; Inositol 1,4,5-Trisphosphate; Lysosomes; Mice; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
Chloroquine induces human mononuclear phagocytes to inhibit and kill Cryptococcus neoformans by a mechanism independent of iron deprivation.
Topics: Ammonium Chloride; Animals; Antifungal Agents; Apoproteins; Chloroquine; Cryptococcosis; Cryptococcus neoformans; Dose-Response Relationship, Drug; Female; HIV Seronegativity; HIV Seropositivity; Humans; Hydrogen-Ion Concentration; Iron; Iron Deficiencies; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, SCID; Monocytes; Phagocytosis; Survival Rate; Transferrin | 1997 |
Low density lipoprotein binding and uptake by human and rat islet beta cells.
Topics: Ammonium Chloride; Animals; Binding Sites; Cells, Cultured; Chloroquine; Humans; Iodine Radioisotopes; Islets of Langerhans; Lipoproteins, LDL; Male; Protein Binding; Rats; Rats, Wistar; Receptors, LDL | 1997 |
Mechanism of Borna disease virus entry into cells.
Topics: Amantadine; Ammonium Chloride; Animals; Borna disease virus; Cell Line; Chloroquine; Cytopathogenic Effect, Viral; Endocytosis; Giant Cells; Hydrogen-Ion Concentration; Lysosomes; Membrane Fusion; Rats; Transcription, Genetic; Viral Proteins; Virus Replication | 1998 |
Processing of Mycobacterium tuberculosis bacilli by human monocytes for CD4+ alphabeta and gammadelta T cells: role of particulate antigen.
Topics: Ammonium Chloride; Antigen Presentation; Antigens, Bacterial; Brefeldin A; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Chloroquine; Cyclopentanes; Cytochalasin D; Cytotoxicity Tests, Immunologic; Formaldehyde; HLA-DR Antigens; Humans; Monocytes; Mycobacterium tuberculosis; Phagocytosis; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta | 1998 |
Lysosomotropic agents ameliorate macrophage dysfunction following the phagocytosis of IgG-coated erythrocytes: a role for lipid peroxidation.
Topics: Ammonium Chloride; Animals; Chloroquine; Erythrocytes; Immunoglobulin G; Lipid Peroxidation; Macrophage Activation; Macrophages, Peritoneal; Methylamines; Phagocytosis; Quinacrine; Rats; Rats, Sprague-Dawley | 1997 |
Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptor-deficient cell lines.
Topics: Ammonium Chloride; Animals; Cattle; Cell Line; Cell Line, Transformed; Chlorocebus aethiops; Chloroquine; COS Cells; Cricetinae; Dogs; Ebolavirus; Gene Expression; Genetic Vectors; HeLa Cells; Humans; Leukemia Virus, Murine; Membrane Glycoproteins; Neutralization Tests; Receptors, Virus; Recombinant Fusion Proteins; Swine; Vero Cells; Viral Matrix Proteins | 1998 |
A modular DNA carrier protein based on the structure of diphtheria toxin mediates target cell-specific gene delivery.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Breast Neoplasms; Chloroquine; COS Cells; Diphtheria Toxin; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Macrolides; Methylamines; Nigericin; Receptor, ErbB-2; Recombinant Fusion Proteins; Single-Chain Antibodies; Transfection; Tumor Cells, Cultured | 1998 |
Entry of African swine fever virus into Vero cells and uncoating.
Topics: 2,4-Dinitrophenol; Adsorption; African Swine Fever Virus; Ammonium Chloride; Animals; Chlorocebus aethiops; Chloroquine; Cytochalasin B; Cytoskeleton; Demecolcine; Endocytosis; Endosomes; Lysosomes; Membrane Fusion; Monensin; Sodium Azide; Vero Cells | 1998 |
Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats | 1998 |
The host-protein-independent iron uptake by Tritrichomonas foetus.
Topics: Amiloride; Ammonium Chloride; Animals; Antiprotozoal Agents; Ascorbic Acid; Cattle; Chloroquine; Ferric Compounds; Iron; Iron Chelating Agents; Lactoferrin; Nitrilotriacetic Acid; Oxidation-Reduction; Sodium Fluoride; Transferrin; Tritrichomonas foetus | 1998 |
Role of endoplasmic reticulum, endosomal-lysosomal compartments, and microtubules in amyloid precursor protein metabolism of human neurons.
Topics: Ammonium Chloride; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Cells, Cultured; Chloroquine; Cysteine Endopeptidases; Endoplasmic Reticulum; Endosomes; Golgi Apparatus; Humans; Lysosomes; Microtubules; Neurons; Peptide Hydrolases; Polymers; Reference Values; Serine Endopeptidases | 1999 |
Phosphorylation of arylsulphatase A occurs through multiple interactions with the UDP-N-acetylglucosamine-1-phosphotransferase proximal and distal to its retrieval site by the KDEL receptor.
Topics: Acetylglucosamine; Ammonium Chloride; Cerebroside-Sulfatase; Chloroquine; Chromatography, High Pressure Liquid; Glucose; Glycosylation; Golgi Apparatus; Hydrogen-Ion Concentration; Hydrolysis; Lysosomes; Mannose; Mannosephosphates; Monensin; N-Acetylneuraminic Acid; Oligosaccharides; Phosphorylation; Primaquine; Protein Sorting Signals; Receptor, IGF Type 2; Receptors, Peptide; Transferases (Other Substituted Phosphate Groups) | 1999 |
Adenovirus cellular receptor site recirculation of HeLa cells upon receptor-mediated endocytosis is not low pH-dependent.
Topics: Adenoviruses, Human; Amantadine; Ammonium Chloride; Chloroquine; Cycloheximide; Endocytosis; HeLa Cells; Humans; Hydrogen-Ion Concentration; Kinetics; Methionine; Monensin; Nigericin; Receptors, Virus; Sulfur Radioisotopes | 1999 |
Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways.
Topics: Ammonium Chloride; Animals; Biological Transport; Cadmium; Cell Line; Cell Membrane; Chloroquine; Cysteine Endopeptidases; Endosomes; Enzyme Stability; Kidney Tubules, Proximal; Leupeptins; Lysosomes; Models, Biological; Multienzyme Complexes; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Serine Proteinase Inhibitors; Sodium-Potassium-Exchanging ATPase; Ubiquitins | 1999 |
Entry of human cytomegalovirus into retinal pigment epithelial and endothelial cells by endocytosis.
Topics: Ammonium Chloride; Cell Membrane; Cells, Cultured; Chloroquine; Cytochalasin B; Cytomegalovirus; Endocytosis; Endothelium, Vascular; Fibroblasts; Fluorescent Antibody Technique, Indirect; Humans; Membrane Fusion; Pigment Epithelium of Eye; Viral Proteins; Virus Replication | 1999 |
MAL, an integral element of the apical sorting machinery, is an itinerant protein that cycles between the trans-Golgi network and the plasma membrane.
Topics: Ammonium Chloride; Animals; Biological Transport; Biotinylation; Brefeldin A; Cell Line; Cell Membrane; Chloroquine; COS Cells; Dogs; Endosomes; Flow Cytometry; Fluorescent Antibody Technique; Glycosylation; Golgi Apparatus; Membrane Transport Proteins; Monensin; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myelin Proteins; Neuraminidase; Nocodazole; Oligopeptides; Peptides; Proteolipids; Recombinant Proteins; Transfection; Transferrin | 1999 |
Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step.
Topics: Ammonium Chloride; Anti-Bacterial Agents; Cell Line; Chloroquine; Cold Temperature; Cytopathogenic Effect, Viral; Humans; Hydrogen-Ion Concentration; Influenza, Human; Macrolides; Membrane Fusion; Microscopy, Electron; Orthomyxoviridae; Protein Synthesis Inhibitors; Viral Proteins | 2000 |
Visualization of acidic compartments in cultured osteoclasts by use of an acidotrophic amine as a marker for low pH.
Topics: Acetazolamide; Acids; Actins; Adenosine Triphosphatases; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antirheumatic Agents; Biomarkers; Carbonic Anhydrase Inhibitors; Cell Compartmentation; Cells, Cultured; Chloroquine; Dinitrobenzenes; Enzyme Inhibitors; Extracellular Space; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Hydrogen-Ion Concentration; Ionophores; Macrolides; Microscopy, Electron; Monensin; Nigericin; Osteoclasts; Rabbits; Vacuoles | 1999 |
Unique processing pathways within recipient antigen-presenting cells determine IgG immunity against donor platelet MHC antigens.
Topics: Ammonium Chloride; Animals; Antibody Specificity; Antigen Presentation; Antigen-Presenting Cells; Blood Donors; Blood Platelets; Brefeldin A; Chloroquine; Colchicine; Cytosol; Endocytosis; Endosomes; Enzyme Activation; Female; H-2 Antigens; Immunoglobulin G; Interleukin-4; Isoantibodies; Leupeptins; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubules; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Platelet Transfusion; T-Lymphocytes, Helper-Inducer; Tubulin | 2000 |
Degradation of human thyroperoxidase in the endoplasmic reticulum involves two different pathways depending on the folding state of the protein.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Antibodies, Monoclonal; Chloroquine; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Emetine; Endoplasmic Reticulum; Humans; Multienzyme Complexes; Peroxidase; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Folding; Thyroid Gland | 2000 |
Weak bases affect late stages of Mayaro virus replication cycle in vertebrate cells.
Topics: Alphavirus; Ammonium Chloride; Animals; Chlorocebus aethiops; Chloroquine; Clone Cells; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Kidney; Male; Microscopy, Electron; Viral Proteins; Virion; Virus Replication | 2000 |
Presence of a Na(+)/H(+) exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs.
Topics: Acridine Orange; Adenosine Triphosphate; Aminoquinolines; Ammonium Chloride; Animals; Antiprotozoal Agents; Butylated Hydroxytoluene; Chloroquine; Hydrogen-Ion Concentration; Leishmania donovani; Pentamidine; Sodium Chloride; Sodium-Hydrogen Exchangers; Vacuoles | 2000 |
Different cytotoxic response to gadolinium between mouse and rat alveolar macrophages.
Topics: Ammonium Chloride; Animals; Apoptosis; Cadmium; Cell Survival; Cells, Cultured; Chloroquine; Culture Media, Conditioned; DNA; DNA Fragmentation; Gadolinium; Macrophages, Alveolar; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phagocytosis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity | 2000 |
Exposure to low pH is not required for penetration of mosquito cells by Sindbis virus.
Topics: Aedes; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Hydrogen-Ion Concentration; Sindbis Virus; Virus Replication | 2001 |
Chloroquine antagonizes the proinflammatory cytokine response to opportunistic fungi by alkalizing the fungal phagolysosome.
Topics: Active Transport, Cell Nucleus; Ammonium Chloride; Anti-Bacterial Agents; Candida albicans; Cell Nucleus; Cell Survival; Cells, Cultured; Chloroquine; Cryptococcus neoformans; Cytokines; Endosomes; Enzyme Inhibitors; HIV Seropositivity; Humans; Hydrogen-Ion Concentration; Leukocytes, Mononuclear; Lysosomes; Macrolides; NF-kappa B; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Molecular kinetics of nerve growth factor receptor trafficking and activation.
Topics: Ammonium Chloride; Animals; Chloroquine; Endocytosis; Immunohistochemistry; Lysosomes; Molecular Weight; Nerve Growth Factor; Neuraminidase; PC12 Cells; Protein Transport; Rats; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Time Factors | 2002 |
Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.
Topics: Ammonium Chloride; Animals; Avian Leukosis Virus; Chick Embryo; Chloroquine; Endocytosis; Endosomes; Fibroblasts; HIV-1; Hydrogen-Ion Concentration; Virion | 2002 |
Chloroquine induces activation of nuclear factor-kappaB and subsequent expression of pro-inflammatory cytokines by human astroglial cells.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Astrocytes; Cells, Cultured; Chloroquine; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Lymphotoxin-alpha; Lymphotoxin-beta; Macrolides; Membrane Proteins; Mice; Microglia; Monocytes; NF-kappa B; Tumor Necrosis Factor-alpha | 2003 |
Targeting of thyroglobulin to transcytosis following megalin-mediated endocytosis: evidence for a preferential pH-independent pathway.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Endocytosis; Hydrogen-Ion Concentration; Low Density Lipoprotein Receptor-Related Protein-2; Rats; Rats, Inbred F344; Thyroglobulin; Thyroid Gland; Triiodothyronine | 2003 |
STUDIES ON THE PHARMACOLOGY OF CHLOROQUINE. RECOMMENDATIONS FOR THE TREATMENT OF CHLOROQUINE RETINOPATHY.
Topics: Ammonium Chloride; Chloroquine; Dimercaprol; Erythrocytes; Hematuria; Metabolism; Ophthalmology; Pharmacology; Retina; Retinal Diseases; Toxicology | 1963 |
Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum.
Topics: Ammonium Chloride; Animals; Antimalarials; Artemisinins; Biotin; Blotting, Western; Chloroquine; Dextrans; Endocytosis; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Hemoglobins; Mefloquine; Microscopy, Electron; Microscopy, Fluorescence; Monensin; Plasmodium falciparum; Quinolones; Sesquiterpenes; Transport Vesicles; Vacuoles | 2004 |
Janus kinase 2 enhances the stability of the mature growth hormone receptor.
Topics: Ammonium Chloride; Cell Line, Tumor; Chloroquine; Cycloheximide; Drug Stability; Human Growth Hormone; Humans; Janus Kinase 2; Lactones; Lysosomes; Molecular Conformation; Proteasome Inhibitors; Protein Synthesis Inhibitors; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Somatotropin; RNA Interference; Signal Transduction; Tissue Distribution | 2005 |
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Topics: Ammonium Chloride; Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Chlorocebus aethiops; Chloroquine; Fluorescent Antibody Technique, Indirect; Glycosylation; Membrane Glycoproteins; Peptidyl-Dipeptidase A; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Spike Glycoprotein, Coronavirus; Vero Cells; Viral Envelope Proteins | 2005 |
Role of urease in megasome formation and Helicobacter pylori survival in macrophages.
Topics: Adsorption; Ammonia; Ammonium Chloride; Animals; Autoantigens; Cell Line; Chloroquine; Enzyme Induction; Female; Gene Deletion; Genes, Reporter; Helicobacter pylori; Hydrogen-Ion Concentration; Lysosomal Membrane Proteins; Macrolides; Macrophages; Macrophages, Peritoneal; Membrane Fusion; Membrane Proteins; Mice; Microscopy, Fluorescence; Nitric Oxide Synthase Type II; Phagocytosis; Phagosomes; Phenotype; Species Specificity; Urease; Vesicular Transport Proteins | 2006 |
Enhancing the effect of radionuclide tumor targeting, using lysosomotropic weak bases.
Topics: Amantadine; Ammonium Chloride; Antimalarials; Antipsychotic Agents; Antiviral Agents; Astatine; Carcinoma, Squamous Cell; Cell Line, Tumor; Chloroquine; Epidermal Growth Factor; Glioma; Humans; Iodine Radioisotopes; Radioimmunotherapy; Radioisotopes; Recombinant Fusion Proteins; Thioridazine | 2007 |
Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses.
Topics: Ammonium Chloride; Animals; Antiviral Agents; Cell Line; Cell Survival; Chloroquine; Cytopathogenic Effect, Viral; Dogs; Hemagglutinin Glycoproteins, Influenza Virus; Hydrogen-Ion Concentration; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Lysosomes; Poultry; RNA, Viral; Time Factors; Virus Replication | 2007 |
Inhibition of betanodavirus infection by inhibitors of endosomal acidification.
Topics: Ammonium Chloride; Animals; Antiviral Agents; Cells, Cultured; Chloroquine; Cytopathogenic Effect, Viral; Endocytosis; Endosomes; Hydrogen-Ion Concentration; Macrolides; Monensin; Nodaviridae | 2007 |
Inhibition of endosome-lysosome system acidification enhances porcine circovirus 2 infection of porcine epithelial cells.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Circovirus; Endosomes; Epithelial Cells; Ionophores; Lysosomes; Monensin; Serine Endopeptidases; Swine; Virus Attachment | 2008 |
Increased yield of porcine circovirus-2 by a combined treatment of PK-15 cells with interferon-gamma and inhibitors of endosomal-lysosomal system acidification.
Topics: Ammonium Chloride; Animals; Cell Line; Chloroquine; Circovirus; Endosomes; Enzyme Inhibitors; Immunologic Factors; Interferon-gamma; Monensin; Swine | 2008 |
Lysosome mediated Kir2.1 breakdown directly influences inward rectifier current density.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Fluorescent Antibody Technique; Humans; Intracellular Fluid; Leupeptins; Lysosomes; Mice; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Time Factors | 2008 |
Expression of sulfotransferases involved in the biosynthesis of chondroitin sulfate E in the bone marrow derived mast cells.
Topics: Ammonium Chloride; Animals; Bone Marrow Cells; Cells, Cultured; Chloroquine; Chondroitin Sulfates; Chromatography, Gel; Chromatography, High Pressure Liquid; Disaccharides; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hydrogen-Ion Concentration; Macrolides; Mast Cells; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sulfotransferases | 2008 |
Enhancement of gene expression efficiency using cationic liposomes on ovarian cancer cells.
Topics: Ammonium Chloride; Cations; Cell Line, Tumor; Chloroquine; Colchicine; Female; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Liposomes; Microscopy, Confocal; Ovarian Neoplasms; Transfection | 2008 |
Inhibition of lysosomal functions reduces proteasomal activity.
Topics: Acetylcysteine; alpha-Synuclein; Ammonium Chloride; Autophagy; Blotting, Western; Cell Line, Tumor; Chloroquine; Enzyme Inhibitors; HSC70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Hydrogen-Ion Concentration; Lysosomes; Neurons; Proteasome Endopeptidase Complex | 2009 |
Lysosome-dependent degradation of Notch3.
Topics: Ammonium Chloride; Animals; Chloroquine; Cysteine Proteinase Inhibitors; Epithelial Cells; HeLa Cells; Humans; Leupeptins; Lysosomes; Mice; Protein Transport; Receptor, Notch3; Receptors, Notch; Signal Transduction; Transfection | 2009 |
Entry of bovine viral diarrhea virus into ovine cells occurs through clathrin-dependent endocytosis and low pH-dependent fusion.
Topics: Ammonium Chloride; Animals; beta-Cyclodextrins; Cell Line; Chloroquine; Chlorpromazine; Clathrin; Diarrhea Virus 1, Bovine Viral; Diarrhea Virus 2, Bovine Viral; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Endocytosis; Hydrogen-Ion Concentration; Sheep; Sucrose; Thymus Gland; Virus Internalization | 2010 |
Enhancement of TAT cell membrane penetration efficiency by dimethyl sulphoxide.
Topics: Active Transport, Cell Nucleus; Ammonium Chloride; Animals; Apoptosis; Capsid Proteins; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Cell Separation; Chloroquine; Cytosol; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Endocytosis; Flow Cytometry; Fluorescein-5-isothiocyanate; Green Fluorescent Proteins; Hemolysis; Hep G2 Cells; Humans; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Recombinant Fusion Proteins; Sodium Azide; tat Gene Products, Human Immunodeficiency Virus; Time Factors | 2010 |
Involvement of lysosomes in the early stages of axon degeneration.
Topics: Amines; Ammonium Chloride; Animals; Animals, Newborn; Axons; Cells, Cultured; Chloroquine; Coloring Agents; Lysosomes; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Time Factors; Wallerian Degeneration | 2010 |
The mechanism of selective transfection mediated by pentablock copolymers; part II: nuclear entry and endosomal escape.
Topics: Ammonium Chloride; Cell Line, Tumor; Cell Nucleus; Chloroquine; DNA; Endodeoxyribonucleases; Endosomes; Humans; Hydrogen-Ion Concentration; Methacrylates; Microscopy, Confocal; Nuclear Localization Signals; Poloxamer; Transfection | 2011 |
Improved antigen cross-presentation by polyethyleneimine-based nanoparticles.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Cross-Priming; Dendritic Cells; Drug Delivery Systems; Genes, MHC Class I; Interleukin-2; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Peptide Fragments; Polyethyleneimine | 2011 |
Lysosomotropic agents as HCV entry inhibitors.
Topics: Ammonium Chloride; Antiviral Agents; Cell Line; Chloroquine; Hepacivirus; Hepatitis C; Humans; Lysosomes; Virus Internalization | 2011 |
Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
Topics: Acetylcysteine; Ammonium Chloride; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Gene Knockout Techniques; HEK293 Cells; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Leupeptins; Lysosomes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; Presenilin-2; Proteasome Inhibitors; Proteolysis; Receptor, Notch1; Transcription, Genetic; Transcriptional Activation; Ubiquitination | 2012 |
Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
Topics: Adaptor Proteins, Vesicular Transport; Amino Acids; Ammonium Chloride; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antibodies, Monoclonal; Aspartic Acid Endopeptidases; Caspase 3; Cell Death; Cell Membrane; Cells, Cultured; Chloroquine; Cycloheximide; Dendritic Spines; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Lysosomes; Male; Membrane Proteins; Mice; Neurons; Neuropeptides; Oligonucleotides; Protein Synthesis Inhibitors; Rats; Transfection | 2012 |
Sjögren's Syndrome Antigen B Acts as an Endogenous Danger Molecule to Induce Interleukin-8 Gene Expression in Polymorphonuclear Neutrophils.
Topics: Ammonium Chloride; Autoantigens; Chloroquine; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; HL-60 Cells; Humans; Interleukin-8; MAP Kinase Signaling System; Microscopy, Fluorescence; Neutrophils; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Ribonucleoproteins; Sjogren's Syndrome; SS-B Antigen; Tumor Necrosis Factor-alpha | 2015 |
Nonstable Staphylococcus aureus Small-Colony Variants Are Induced by Low pH and Sensitized to Antimicrobial Therapy by Phagolysosomal Alkalinization.
Topics: Ammonium Chloride; Animals; Anti-Bacterial Agents; Cell Line, Tumor; Chloroquine; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Genetic Variation; Humans; Hydrogen-Ion Concentration; Macrolides; Mice; Mice, Inbred C57BL; Phagosomes; Staphylococcal Infections; Staphylococcus aureus | 2016 |
CNOT2 promotes degradation of p62/SQSTM1 as a negative regulator in ATG5 dependent autophagy.
Topics: Adenine; Adipogenesis; Ammonium Chloride; Apoptosis; Autophagy; Autophagy-Related Protein 5; Cell Cycle; Cell Differentiation; Chloroquine; HEK293 Cells; Humans; Repressor Proteins; RNA-Binding Proteins; RNA, Small Interfering; Sequestosome-1 Protein; Signal Transduction; Ubiquitination; Up-Regulation | 2017 |
Autophagy enhances the replication of Peste des petits ruminants virus and inhibits caspase-dependent apoptosis in vitro.
Topics: Ammonium Chloride; Androstadienes; Animals; Apoptosis; Autophagosomes; Autophagy; Autophagy-Related Protein 7; Beclin-1; Caspases; Chloroquine; Endometrium; Epithelial Cells; Female; Goats; Host-Pathogen Interactions; Humans; In Vitro Techniques; Lysosomes; Nucleoproteins; Peste-des-Petits-Ruminants; Peste-des-petits-ruminants virus; Protein C; Virus Replication; Wortmannin | 2018 |
Entry of sapelovirus into IPEC-J2 cells is dependent on caveolae-mediated endocytosis.
Topics: Ammonium Chloride; Animals; Caveolae; Cell Line; Chloroquine; Clathrin; Dynamins; Endocytosis; Epithelial Cells; Hydrazones; Nystatin; Picornaviridae; RNA Interference; RNA, Small Interfering; Swine; Virus Internalization | 2019 |
Interfering with endolysosomal trafficking enhances release of bioactive exosomes.
Topics: Ammonium Chloride; Biological Transport; Biomarkers; Cell Cycle Proteins; Cell Line, Tumor; Chloroquine; Endosomes; Endothelial Cells; Exosomes; Humans; Intracellular Signaling Peptides and Proteins; Lysosomes; MAP Kinase Signaling System; Myocardium; Neovascularization, Physiologic; Phosphorylation; Proto-Oncogene Proteins c-akt; Stem Cells | 2019 |
Inhibitors of endosomal acidification suppress SARS-CoV-2 replication and relieve viral pneumonia in hACE2 transgenic mice.
Topics: Ammonium Chloride; Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Chloroquine; COVID-19; COVID-19 Drug Treatment; Endosomes; Female; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Lung; Macrolides; Mice; Mice, Transgenic; Random Allocation; SARS-CoV-2; Vero Cells; Virus Replication | 2021 |
Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors.
Topics: Ammonium Chloride; Angiotensin-Converting Enzyme 2; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Chloroquine; Clathrin; COVID-19; COVID-19 Drug Treatment; Drug Synergism; Endocytosis; Endosomes; Humans; Hydrogen-Ion Concentration; Hydroxychloroquine; Macrolides; Niclosamide; Protein Binding; Protein Domains; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Vero Cells; Virus Internalization | 2021 |