chloroquine and allopurinol

chloroquine has been researched along with allopurinol in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's2 (8.00)18.2507
2000's6 (24.00)29.6817
2010's10 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Berman, PA; Freese, JA; Human, L1
Berman, PA; Human, L1
Au, AM; Chan, PH; Fishman, RA1
Barg, TsM1
Ignarro, LJ1
Rothermich, NO1
Datko, LJ; Kassarich, J; Rosenthale, ME; Schneider, F1
Giles, CL1
Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF1

Reviews

4 review(s) available for chloroquine and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Eye complications during use of various medicinal substances with general effects (review of the literature)].
    Oftalmologicheskii zhurnal, 1969, Volume: 24, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Allopurinol; Anti-Bacterial Agents; Antimalarials; Cardiac Glycosides; Cataract; Child; Chloroquine; Chlorpromazine; Epinephrine; Ethambutol; Ethchlorvynol; Eye Diseases; Female; Humans; Miotics; Nalidixic Acid; Phosphates; Pilocarpine; Quinolines; Retinal Degeneration; Warfarin

1969
An updated look at antirheumatic drugs.
    The Medical clinics of North America, 1967, Volume: 51, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Azathioprine; Chloroquine; Cyclophosphamide; Glucocorticoids; Humans; Immunosuppressive Agents; Indomethacin; Methotrexate; Nitrogen Mustard Compounds; Rheumatic Diseases; Salicylates

1967
Problems of antiarthritic therapy in the elderly.
    Journal of the American Geriatrics Society, 1984, Volume: 32, Issue:3

    Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Chloroquine; Female; Gold; Gout; Humans; Male; Methotrexate; Middle Aged; Osteoarthritis; Penicillamine; Probenecid

1984

Other Studies

21 other study(ies) available for chloroquine and allopurinol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Xanthine oxidase inhibits growth of Plasmodium falciparum in human erythrocytes in vitro.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:6

    Topics: Animals; Cells, Cultured; Chloroquine; Dose-Response Relationship, Drug; Erythrocytes; Glycine; Humans; Hypoxanthine; Hypoxanthines; Plasmodium falciparum; Purines; Superoxide Dismutase; Xanthine Oxidase

1991
Hypoxanthine depletion induced by xanthine oxidase inhibits malaria parasite growth in vitro.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Adenine; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Catalase; Chloroquine; Erythrocytes; Glycine; Humans; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Plasmodium falciparum; Purines; Superoxide Dismutase; Xanthine Oxidase

1991
Stimulation of phospholipase A2 activity by oxygen-derived free radicals in isolated brain capillaries.
    Journal of cellular biochemistry, 1985, Volume: 27, Issue:4

    Topics: Animals; Brain; Capillaries; Chloroquine; Fatty Acids; Fatty Acids, Unsaturated; Free Radicals; Oxygen; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Quinacrine; Rats; Rats, Inbred Strains; Xanthine Oxidase

1985
Release of neutral protease and beta-glucuronidase from human neutrophils in the presence of cartilage treated with various immunologic reactants.
    Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 113, Issue:1

    Topics: Allopurinol; Arthritis, Rheumatoid; Aspirin; Cartilage; Chloroquine; Colchicine; Factor VIII; Glucuronidase; Hot Temperature; Humans; Immunoglobulin G; Indomethacin; Iodine Radioisotopes; L-Lactate Dehydrogenase; Methylprednisolone; Neutrophils; Peptide Hydrolases; Probenecid; Protein Denaturation; Sulfur Radioisotopes; Synovial Fluid; Triamcinolone Acetonide; Vinblastine

1974
Chemotherapy of experimental allergic encephalomyelitis (EAE).
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2

    Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; Chloroquine; Colchicine; Cortisone; Cyclophosphamide; Cyproheptadine; Diazoxide; Dimethyl Sulfoxide; Encephalomyelitis, Autoimmune, Experimental; Hydrocortisone; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Methyldopa; Nialamide; Oils; Organ Size; Rats; Strychnine; Talc; Thalidomide; Thioguanine; Thiomalates

1969
Ocular complications in the treatment of joint disease.
    Michigan medicine, 1971, Volume: 70, Issue:13

    Topics: Adrenal Cortex Hormones; Adult; Allopurinol; Anti-Inflammatory Agents; Child; Chloroquine; Eye Diseases; Female; Gold; Humans; Indomethacin; Joint Diseases; Male; Phenylbutazone; Salicylates

1971