chloroquine has been researched along with akt-i-1,2 compound in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, C; Lee, H; Solomon, VR; Ulibarri, G | 1 |
| Davis, DP; De Mazière, A; Degtyarev, M; Friedman, LS; Gray, DC; Hoeflich, KP; Klumperman, J; Lee, BB; Lin, J; Lin, K; Murray, LJ; Orr, C; Prior, WW; Stern, HM; Tien, JY; van Dijk, S; Wu, H | 1 |
| Bertrand, M; Correa, RJ; DiMattia, GE; Fazio, EN; McGee, J; Peart, TM; Préfontaine, M; Shepherd, TG; Sugimoto, A; Valdes, YR | 1 |
3 other study(ies) available for chloroquine and akt-i-1,2 compound
| Article | Year |
|---|---|
The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Chloroquine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Molecular Structure; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinoxalines; Stereoisomerism; Structure-Activity Relationship | 2008 |
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 7; Benzylamines; Cell Cycle; Cell Line, Tumor; Chloroquine; Drug Interactions; Female; Furans; Humans; Lysosomes; Macrolides; Mice; Mice, Nude; Mitochondria; Mutation; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proton-Translocating ATPases; PTEN Phosphohydrolase; Pyridines; Pyrimidines; Quinoxalines; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Ubiquitin-Activating Enzymes; Xenograft Model Antitumor Assays | 2008 |
Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability.
Topics: Allosteric Regulation; Antineoplastic Agents; Ascites; Autophagy; Benzylamines; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Inhibitory Concentration 50; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Quinazolines; Quinoxalines; Spheroids, Cellular | 2014 |