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chloroform and phosgene

chloroform has been researched along with phosgene in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's1 (3.33)18.2507
2000's6 (20.00)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
George, JW; Krishna, G; Martin, JL; Pohl, LR1
Beaune, P; Cresteil, T; Lange, M; Leroux, JP; Mansuy, D1
Bhooshan, B; Krishna, G; Pohl, LR; Whittaker, NF1
Christiansen, VO; Dahlberg, JA; Eriksson, EA1
Legg, EF1
Rinzema, LC; Silverstein, LG1
Branchflower, RV; Highet, RJ; Hook, JB; Nunn, DS; Pohl, LR; Smith, JH1
Branchflower, RV; George, JW; Pohl, LR; Schulick, RD1
Cowlen, MS; Hewitt, WR; Schroeder, F1
Bailie, MB; Hook, JB; Newton, JF; Smith, JH1
George, JW; Martin, JL; Pohl, LR1
Anders, MW; Harris, RN1
Fagerlund, C; Hartvig, P1
Recknagel, RO; Waller, RL1
Anders, MW; Stevens, JL1
Balduzzi, M; Guastadisegni, C; Vitozzi, L1
De Angelis, G; Di Consiglio, E; Testai, E; Vittozzi, L1
Boobis, AR; Edwards, RJ; Fabrizi, L; Taylor, GW1
Devereaux, A; Lazarus, AA1
Boobis, AR; CaƱas, B; Edwards, RJ; Fabrizi, L; Taylor, GW1
PETRUKHIN, VG1
GERARD, RW; POTTS, AM; SIMON, FP1
Lambert, WE; Maudens, KE; Wille, SM1
POSTEL, S; TOBIAS, JM2
Anim-Danso, E; Joy, A; Kohn, J1
Pauluhn, J1
Bharatam, PV; Bhatia, S; Dixit, VA; Jangra, H1
Alston, TA1
Kang, Y; Kim, BG; Kim, KC; Kwon, JE; Lee, I1

Reviews

2 review(s) available for chloroform and phosgene

ArticleYear
Potential agents of chemical warfare. Worst-case scenario protection and decontamination methods.
    Postgraduate medicine, 2002, Volume: 112, Issue:5

    Topics: Chemical Warfare Agents; Chlorine; Chloroform; Cyanides; Decontamination; Humans; Phosgene; Riot Control Agents, Chemical

2002
Noteworthy Chemistry of Chloroform.
    Journal of anesthesia history, 2016, Volume: 2, Issue:3

    Topics: Anesthesia; Anesthesiology; Chloroform; History, 19th Century; History, 20th Century; Humans; Phosgene

2016

Other Studies

28 other study(ies) available for chloroform and phosgene

ArticleYear
Deuterium isotope effect in in vivo bioactivation of chloroform to phosgene.
    Biochemical pharmacology, 1979, Volume: 28, Issue:4

    Topics: Animals; Biotransformation; Chloroform; Deuterium; In Vitro Techniques; Male; Phosgene; Rats

1979
Evidence for phosgene formation during liver microsomal oxidation of chloroform.
    Biochemical and biophysical research communications, 1977, Nov-21, Volume: 79, Issue:2

    Topics: Aerobiosis; Animals; Chloroform; Computers; Male; Mass Spectrometry; Microsomes, Liver; Phosgene; Rats

1977
Phosgene: a metabolite of chloroform.
    Biochemical and biophysical research communications, 1977, Dec-07, Volume: 79, Issue:3

    Topics: Animals; Chloroform; Chromatography, Gas; Cysteine; Male; Mass Spectrometry; Microsomes, Liver; Phosgene; Protein Binding; Proteins; Rats

1977
On the formation of phosgene by photo-oxidation of methyl chloroform in welding.
    The Annals of occupational hygiene, 1973, Volume: 16, Issue:1

    Topics: Chloroform; Oxidation-Reduction; Phosgene; Photochemistry; Radiation; Solvents; Welding

1973
Phosgene production during aspiration of trichloroacetic acid into a flame emission spectrophotometer.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Jan-19, Volume: 50, Issue:1

    Topics: Chlorine; Chloroform; Decarboxylation; Evaluation Studies as Topic; Methods; Phosgene; Spectrophotometry; Trichloroacetic Acid

1974
Hazards from chlorinated hydrocarbon decomposition during welding.
    American Industrial Hygiene Association journal, 1972, Volume: 33, Issue:1

    Topics: Carbon Dioxide; Carbon Monoxide; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Chlorides; Chlorine; Chloroform; Environmental Exposure; Ethylenes; Hydrocarbons, Halogenated; Infrared Rays; Maximum Allowable Concentration; Methyl Chloride; Nitrogen Oxides; Occupational Medicine; Phosgene; Tetrachloroethylene; Trichloroethylene; Ventilation; Welding

1972
Nephrotoxicity of chloroform: metabolism to phosgene by the mouse kidney.
    Toxicology and applied pharmacology, 1984, Volume: 72, Issue:1

    Topics: Animals; Chloroform; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Kidney; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Phosgene

1984
Comparison of the effects of methyl-N-butyl ketone and phenobarbital on rat liver cytochromes P-450 and the metabolism of chloroform to phosgene.
    Toxicology and applied pharmacology, 1983, Volume: 71, Issue:3

    Topics: Animals; Benzphetamine; Chloroform; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; Ketones; Male; Methyl n-Butyl Ketone; Microsomes, Liver; Phenobarbital; Phosgene; Rats; Rats, Inbred Strains

1983
2-hexanone potentiation of [14C]chloroform hepatotoxicity: covalent interaction of a reactive intermediate with rat liver phospholipid.
    Toxicology and applied pharmacology, 1984, Volume: 73, Issue:3

    Topics: Animals; Biotransformation; Chloroform; Chromatography, Thin Layer; Drug Synergism; Glutathione; In Vitro Techniques; Ketones; Liver; Macromolecular Substances; Male; Methyl n-Butyl Ketone; Phosgene; Phospholipids; Rats; Rats, Inbred F344

1984
Mechanism of chloroform nephrotoxicity. IV. Phenobarbital potentiation of in vitro chloroform metabolism and toxicity in rabbit kidneys.
    Toxicology and applied pharmacology, 1984, Jun-30, Volume: 74, Issue:2

    Topics: Animals; Chloroform; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Diseases; Male; Microsomes; p-Aminohippuric Acid; Phenobarbital; Phosgene; Pyrrolidonecarboxylic Acid; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Thiazoles; Thiazolidines

1984
Mechanism of metabolic activation of chloroform by rat liver microsomes.
    Biochemical pharmacology, 1980, Volume: 29, Issue:24

    Topics: Animals; Biotransformation; Carbon Dioxide; Chlorides; Chloroform; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phosgene; Proteins; Rats

1980
Phosgene: a possible role in the potentiation of carbon tetrachloride hepatotoxicity by 2-propanol.
    Life sciences, 1981, Aug-03, Volume: 29, Issue:5

    Topics: 1-Propanol; Animals; Carbon Dioxide; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Male; Microsomes, Liver; Phenobarbital; Phosgene; Rats

1981
A simplified method for the gas chromatographic determination of pethidine and norpethidine after derivatization with trichloroethyl chloroformate.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Chloroform; Chromatography, Gas; Humans; Meperidine; Phosgene

1983
Evaluation of a role for phosgene production in the hepatotoxic mechanism of action of carbon tetrachloride and bromotrichloromethane.
    Toxicology and applied pharmacology, 1982, Volume: 66, Issue:2

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Cysteine; Lipid Peroxides; Liver; Male; Microsomes, Liver; Phosgene; Rats; Rats, Inbred Strains

1982
Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform.
    Chemico-biological interactions, 1981, Volume: 37, Issue:1-2

    Topics: Alanine Transaminase; Animals; Biotransformation; Chloroform; Cysteine; Liver; Male; Maleates; Phenobarbital; Phosgene; Rats; Rats, Inbred Strains

1981
Preliminary characterization of phospholipid adducts formed by [14C]-CHCl3 reactive intermediates in hepatocyte suspensions.
    Journal of biochemical toxicology, 1996, Volume: 11, Issue:1

    Topics: Animals; Carbon Radioisotopes; Carcinogens; Cardiolipins; Cell Separation; Cells, Cultured; Chloroform; Chromatography, Thin Layer; Isotope Labeling; Liver; Male; Phosgene; Phospholipids; Rats; Rats, Sprague-Dawley; Software; Solvents

1996
Correlation of a specific mitochondrial phospholipid-phosgene adduct with chloroform acute toxicity.
    Toxicology, 2001, Feb-21, Volume: 159, Issue:1-2

    Topics: Animals; Chemical Warfare Agents; Chloroform; Chromatography, Thin Layer; Kidney; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred Strains; Mitochondria; Phosgene; Phospholipids; Rats; Rats, Sprague-Dawley; Subcellular Fractions

2001
Adducts of the chloroform metabolite phosgene.
    Advances in experimental medicine and biology, 2001, Volume: 500

    Topics: Amino Acids; Chemical Warfare Agents; Chloroform; Deoxyguanosine; Glutathione; Histones; Muramidase; Peptides; Phosgene

2001
Adduction of the chloroform metabolite phosgene to lysine residues of human histone H2B.
    Chemical research in toxicology, 2003, Volume: 16, Issue:3

    Topics: Amino Acid Sequence; Chloroform; Histones; Humans; Lysine; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Phosgene; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin

2003
[Effect of sleep disorders on the course and outcome of diphosgene pulmonary edema].
    Arkhiv patologii, 1959, Volume: 21(8)

    Topics: Chloroform; Phosgene; Pulmonary Edema; Sleep Wake Disorders

1959
The mechanism of action of phosgene and diphosgene.
    Archives of biochemistry, 1949, Volume: 24, Issue:2

    Topics: Chloroform; Gases; Humans; Phosgene

1949
Traces of phosgene in chloroform: consequences for extraction of anthracyclines.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Apr-01, Volume: 848, Issue:2

    Topics: Amines; Anthracyclines; Chloroform; Chromatography, Liquid; Daunorubicin; Doxorubicin; Epirubicin; Ethanol; Idarubicin; Molecular Structure; Phosgene; Reproducibility of Results; Solvents; Spectrometry, Fluorescence

2007
Localization of the site of action of a pulmonary irritant, diphosgene.
    The American journal of physiology, 1949, Volume: 158, Issue:2

    Topics: Chloroform; Gas Poisoning; Humans; Irritants; Lung; Phosgene

1949
Simple, rapid, and highly sensitive detection of diphosgene and triphosgene by spectrophotometric methods.
    Talanta, 2009, Nov-15, Volume: 80, Issue:1

    Topics: Chloroform; Fluorescence; Fluorescent Dyes; Isoxazoles; Oxidation-Reduction; Phosgene; Polycarboxylate Cement; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2009
The effect of exercise on mortality of animals poisoned with diphosgene.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1946, Volume: 63, Issue:2

    Topics: Animals; Chloroform; Exercise; Gas Poisoning; Phosgene

1946
Acute nose-only inhalation exposure of rats to di- and triphosgene relative to phosgene.
    Inhalation toxicology, 2011, Volume: 23, Issue:2

    Topics: Administration, Inhalation; Administration, Intranasal; Air Pollutants; Animals; Body Weight; Chemical Phenomena; Chloroform; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Male; Phosgene; Random Allocation; Rats; Rats, Wistar; Sex Characteristics; Specific Pathogen-Free Organisms; Survival Analysis; Toxicity Tests, Acute

2011
Formation/fate of reactive metabolites from general anesthetics and a comparison of toxic and non-toxic analogues: a DFT study.
    Drug metabolism letters, 2012, Volume: 6, Issue:4

    Topics: Anesthetics, General; Chloroform; Halothane; Phosgene; Thermodynamics

2012
Instantaneous Detection of Trichlorinated Carbon via Photo-Induced Electron Transfer toward Chemosensor for Toxic Organochlorides.
    ACS sensors, 2018, 09-28, Volume: 3, Issue:9

    Topics: Aniline Compounds; Chloroform; Electron Spin Resonance Spectroscopy; Electrons; Fluorescence; Fluorescent Dyes; Molecular Structure; Oxidation-Reduction; Phosgene; Spectrometry, Fluorescence; Ultraviolet Rays

2018