Compounds > chloroform
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chloroform and buthionine sulfoximine

chloroform has been researched along with buthionine sulfoximine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bus, JS; Norton, R; White, RD1
Gemma, S; Sbraccia, M; Testai, E; Vittozzi, L1
Beddowes, EJ; Chipman, JK; Faux, SP1
Anand, SS; Latendresse, JR; Mehendale, HM; Mumtaz, MM; Palkar, PS; Philip, BK1

Other Studies

4 other study(ies) available for chloroform and buthionine sulfoximine

ArticleYear
The effect of buthionine sulfoximine, an inhibitor of glutathione synthesis, on hepatic drug metabolism in the male mouse.
    Toxicology letters, 1984, Volume: 23, Issue:1

    Topics: Animals; Biotransformation; Buthionine Sulfoximine; Carbon Tetrachloride Poisoning; Chloroform; Cytochrome P-450 Enzyme System; Glutathione; Glutathione Transferase; Liver; Male; Methionine Sulfoximine; Mixed Function Oxygenases; Oxygenases; Rats; Rats, Inbred F344; Sulfhydryl Compounds

1984
In vivo production of different chloroform metabolites: effect of phenobarbital and buthionine sulfoximine pretreatment.
    Environmental health perspectives, 1994, Volume: 102 Suppl 9

    Topics: Animals; Buthionine Sulfoximine; Chloroform; Injections, Intraperitoneal; Male; Methionine Sulfoximine; Microsomes, Liver; Phenobarbital; Phospholipids; Rats; Rats, Sprague-Dawley

1994
Chloroform, carbon tetrachloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress.
    Toxicology, 2003, May-03, Volume: 187, Issue:2-3

    Topics: Animals; Buthionine Sulfoximine; Carbon Tetrachloride; Cell Line; Chloroform; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Female; Glutathione; Hepatocytes; Humans; Lipid Peroxidation; Models, Biological; Mutagens; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2003
Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform.
    Toxicology and applied pharmacology, 2006, Oct-01, Volume: 216, Issue:1

    Topics: Alanine Transaminase; Animals; Area Under Curve; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Tolerance; Glutathione; Glutathione Reductase; Hepatocytes; Intubation, Gastrointestinal; Kidney; Kidney Diseases; Liver Diseases; Mice; Survival Rate

2006