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chloroform and bromotrichloromethane

chloroform has been researched along with bromotrichloromethane in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199033 (75.00)18.7374
1990's11 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benigni, R; Cotta-Ramusino, M; Gallo, G; Giorgi, F1
Gillette, JR; Krishna, G; Sipes, IG1
Davis, ER; Floyd, RA; Janzen, EG; McCay, PB; Poyer, JL1
Dessì, MA; Dore, M; Montaldo, C; Sanna, A1
Cantor, KP; Hoover, R; Mason, TJ; McCabe, LJ1
Albrecht, DK; Kappus, H; Remmer, H1
Dessì, A; Dore, M; Montaldo, C; Sanna, A; Vargiolu, S1
Gravela, E1
Glende, EA; Recknagel, RO1
Mehendale, HM; Rao, SB; Young, RA1
Cai, Z; Mehendale, HM1
Mehendale, HM1
Alston, TA1
Hidalgo, FJ; Tappel, AL; Zamora, R1
Chen, L; Cotter, RJ; Griffin, PR; Hunt, DF; Martin, BM; Murphy, AC; Osawa, Y; Pohl, LR; Shabanowitz, J; Yates, JR1
Tampo, Y; Yonaha, M1
Brauer, M; Foxall, DL; Janzen, EG; Renaud, I; Towner, RA1
Benedetti, A; Fulceri, R; Graf, P; Romani, A; Sies, H1
Brauer, M; Janzen, EG; Ling, MF; Towner, RA1
Connor, HD; LaCagnin, LB; Mason, RP; Thurman, RG1
Brauer, M; Janzen, EG; Towner, RA1
Bennett, MV; Sáez, JC; Spray, DC1
Benedetti, A; Comporti, M; de Santi, MM; Gardi, C; Lungarella, G1
Motchnik, PA; Sano, M; Tappel, AL1
Negro, F; Panagini, C; Paradisi, L; Parola, M; Torrielli, MV1
Harrison, GG; Ivanetich, KM; Manca, V1
Benedetti, A; Comporti, M; Fulceri, R2
Cambon-Gros, C; Carrera, G; Mitjavila, S1
Brattin, WJ; Waller, RL1
Brattin, WJ; Hegarty, JM; Recknagel, RO1
Gould, DH; Hawk-Prather, K; Story, DL; Tyson, CA1
Glende, EA; Recknagel, RO; Waller, RL1
Corongiu, FP; Lai, M; Milia, A1
Branchflower, RV; Loew, GH; Mico, BA; Pohl, LR; Pudzianowski, AT1
Benedetti, A; Comporti, M; Esterbauer, H; Ferrali, M; Fulceri, R1
Benedetti, A; Ciccoli, L; Comporti, M; Esterbauer, H; Ferrali, M; Fulceri, R1
Recknagel, RO; Waller, RL1
Glende, EA; Lowrey, K; Recknagel, RO2
Gee, DL; Tappel, AL1
Glende, EA; Lowrey, K; Recknagel, RO; Waller, RL1
Cazzaro, S; Ferrara, R; Manno, M; Rezzadore, M; Tolando, R1
Azri-Meehan, S; Brendel, K; Gandolfi, AJ; Mata, HP1

Reviews

1 review(s) available for chloroform and bromotrichloromethane

ArticleYear
Role of hepatocellular regeneration and hepatolobular healing in the final outcome of liver injury. A two-stage model of toxicity.
    Biochemical pharmacology, 1991, Aug-22, Volume: 42, Issue:6

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Cell Division; Chlordecone; Chloroform; Liver; Liver Regeneration; Wound Healing

1991

Other Studies

43 other study(ies) available for chloroform and bromotrichloromethane

ArticleYear
Molecular similarity matrices and quantitative structure-activity relationships: a case study with methodological implications.
    Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4

    Topics: Aneuploidy; Aspergillus nidulans; Hydrocarbons, Halogenated; Models, Chemical; Molecular Conformation; Mutagens; Structure-Activity Relationship

1995
Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450.
    Life sciences, 1977, May-01, Volume: 20, Issue:9

    Topics: Allylisopropylacetamide; Animals; Bromotrichloromethane; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Glutathione; Immune Sera; In Vitro Techniques; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitrogen; Proadifen; Protein Binding; Rats

1977
Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane.
    Biochimica et biophysica acta, 1978, Mar-20, Volume: 539, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Computers; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Male; Microsomes, Liver; Models, Chemical; NADP; Oxidation-Reduction; Rats; Spin Labels

1978
[Further investigations on the protective effect of cadmium acetate in bromotrichloromethane poisoning].
    Bollettino della Societa italiana di biologia sperimentale, 1979, Feb-28, Volume: 55, Issue:4

    Topics: Acetates; Animals; Bromotrichloromethane; Cadmium; Chemical Precipitation; Chloroform; Lipid Metabolism; Liver; Malondialdehyde; Peroxidases; Polyribosomes; Rats

1979
Associations of cancer mortality with halomethanes in drinking water.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:4

    Topics: Brain Neoplasms; Bromotrichloromethane; Chloroform; Epidemiologic Methods; Female; Humans; Kidney Neoplasms; Lymphoma; Male; Neoplasms; Occupational Diseases; Risk; United States; Urinary Bladder Neoplasms; Water Pollutants; Water Pollutants, Chemical

1978
Lipid peroxidation and cell damage in isolated hepatocytes due to bromotrichloromethane.
    Toxicology and applied pharmacology, 1978, Volume: 46, Issue:2

    Topics: Animals; Bromotrichloromethane; Chloroform; Lipid Metabolism; Liver; Male; Malondialdehyde; Oxygen Consumption; Peroxides; Rats; Trypan Blue

1978
[Protective effect of cadmium acetate in trichlorobromomethane poisoning].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Sep-15, Volume: 54, Issue:17

    Topics: Acetates; Animals; Bromotrichloromethane; Cadmium; Chemical and Drug Induced Liver Injury; Chloroform; Female; Liver; Male; Rats

1978
In vitro inhibition of polyphenylalanine synthesis by bromotrichloromethane. Evidence for an oxidative mechanism.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 11, Issue:4

    Topics: Animals; Bromotrichloromethane; Chloroform; Cysteine; Depression, Chemical; Dithiothreitol; In Vitro Techniques; Magnesium; Male; Malondialdehyde; Mitochondria, Liver; Oxidation-Reduction; Peptide Biosynthesis; Peptide Chain Initiation, Translational; Phenylalanine; Rats; Sulfhydryl Compounds

1975
Phospholipase A2 activation and cell injury in isolated rat hepatocytes exposed to bromotrichloromethane, chloroform, and 1,1-dichloroethylene as compared to effects of carbon tetrachloride.
    Toxicology and applied pharmacology, 1992, Volume: 113, Issue:1

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Dichloroethylenes; Enzyme Activation; L-Lactate Dehydrogenase; Liver; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains

1992
Perturbations in polyamines and related enzymes following chlordecone-potentiated bromotrichloromethane hepatotoxicity.
    Journal of biochemical toxicology, 1990,Spring, Volume: 5, Issue:1

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Alanine Transaminase; Amino Acids, Diamino; Animals; Aspartate Aminotransferases; Bromotrichloromethane; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Insecticides; Liver; Male; Ornithine Decarboxylase; Polyamines; Putrescine; Rats; Rats, Inbred Strains

1990
Hepatotoxicity and lethality of halomethanes in Mongolian gerbils pretreated with chlordecone, phenobarbital or mirex.
    Archives of toxicology, 1991, Volume: 65, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chlordecone; Chloroform; DNA; Dose-Response Relationship, Drug; Gerbillinae; Lethal Dose 50; Liver; Male; Mirex; Phenobarbital; Species Specificity

1991
Inhibition of vitamin B12-dependent methionine biosynthesis by chloroform and carbon tetrachloride.
    Biochemical pharmacology, 1991, Nov-27, Volume: 42, Issue:12

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Escherichia coli; Methionine; Nitrous Oxide; Trichloroethanes; Vitamin B 12

1991
Oxidant-induced haemoprotein degradation in rat tissue slices: effect of bromotrichloromethane, antioxidants and chelators.
    Biochimica et biophysica acta, 1990, Mar-01, Volume: 1037, Issue:3

    Topics: Animals; Antioxidants; Bromotrichloromethane; Chelating Agents; Chloroform; Electrophoresis, Polyacrylamide Gel; Free Radicals; Hemeproteins; Kidney; Kinetics; Lipid Peroxidation; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Thiobarbiturates

1990
Metabolism-based covalent bonding of the heme prosthetic group to its apoprotein during the reductive debromination of BrCCl3 by myoglobin.
    The Journal of biological chemistry, 1990, Jun-25, Volume: 265, Issue:18

    Topics: Amino Acid Sequence; Apoproteins; Bromotrichloromethane; Chloroform; Chromatography, High Pressure Liquid; Cyanogen Bromide; Fourier Analysis; Heme; Hydrolysis; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Myoglobin; Oxidation-Reduction; Peptide Fragments

1990
Vitamin E and glutathione are required for preservation of microsomal glutathione S-transferase from oxidative stress in microsomes.
    Pharmacology & toxicology, 1990, Volume: 66, Issue:4

    Topics: Animals; Antioxidants; Bromotrichloromethane; Chloroform; Glutathione; Glutathione Transferase; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains; Sulfobromophthalein; Vitamin E

1990
In vivo proton nuclear magnetic resonance imaging and spectroscopy studies of halocarbon-induced liver damage.
    Magnetic resonance in medicine, 1989, Volume: 9, Issue:2

    Topics: Administration, Inhalation; Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Halothane; Lipids; Liver; Magnetic Resonance Spectroscopy; Protons; Rats; Water

1989
Ca2+ mobilization by vasopressin and glucagon in perfused livers. Effect of prior intoxication with bromotrichloromethane.
    Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11

    Topics: Animals; Bromotrichloromethane; Calcium; Cell Membrane; Chloroform; Glucagon; Glucose; Inositol Phosphates; Liver; Microsomes, Liver; Mitochondria; Oxygen Consumption; Rats; Rats, Inbred Strains; Vasopressins

1989
In vivo and in vitro 31P-NMR spectroscopy of rat liver treated with halocarbons.
    Biochimica et biophysica acta, 1989, Oct-13, Volume: 993, Issue:1

    Topics: Adenine Nucleotides; Animals; Bromotrichloromethane; Carbon Tetrachloride Poisoning; Chloroform; Free Radicals; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Phosphates; Phosphorus; Rats; Rats, Inbred Strains; Reference Values

1989
The carbon dioxide anion radical adduct in the perfused rat liver: relationship to halocarbon-induced toxicity.
    Molecular pharmacology, 1988, Volume: 33, Issue:3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bromotrichloromethane; Carbon Dioxide; Carbon Tetrachloride; Chloroform; Electron Spin Resonance Spectroscopy; Female; Free Radicals; L-Lactate Dehydrogenase; Liver; Oxygen Consumption; Perfusion; Rats; Rats, Inbred Strains

1988
Factors influencing the formation of the carbon dioxide radical anion (.CO2-) spin adduct of PBN in the rat liver metabolism of halocarbons.
    Free radical research communications, 1988, Volume: 4, Issue:6

    Topics: Animals; Bromotrichloromethane; Carbon Dioxide; Carbon Tetrachloride; Chloroform; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Nitrogen Oxides; Rats; Rats, Inbred Strains; Spin Labels

1988
Carbon tetrachloride at hepatotoxic levels blocks reversibly gap junctions between rat hepatocytes.
    Science (New York, N.Y.), 1987, May-22, Volume: 236, Issue:4804

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chloroform; Electric Conductivity; Intercellular Junctions; Liver; Rats

1987
Bromotrichloromethane-induced damage to bronchiolar Clara cells.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 57, Issue:2

    Topics: Animals; Bromotrichloromethane; Bronchi; Carbon Tetrachloride; Chloroform; Lipid Peroxides; Male; Rats; Rats, Inbred Strains

1987
Halogenated hydrocarbon and hydroperoxide-induced peroxidation in rat tissue slices.
    Journal of free radicals in biology & medicine, 1986, Volume: 2, Issue:1

    Topics: Animals; Bromotrichloromethane; Chloroform; Free Radicals; Glutathione; In Vitro Techniques; Lipid Peroxides; Liver; Male; Peroxides; Rats; Rats, Inbred Strains; tert-Butylhydroperoxide; Testis; Thiobarbiturates

1986
Behaviour of cyclic nucleotides and Ca2+ levels in liver tissue of rats poisoned by white phosphorus and trichlorobromomethane.
    Cell biochemistry and function, 1984, Volume: 2, Issue:2

    Topics: Animals; Bromotrichloromethane; Calcium; Chloroform; Cyclic AMP; Cyclic GMP; Liver; Male; Nucleotides, Cyclic; Phosphorus; Rats; Rats, Inbred Strains

1984
Influence of two haloalkanes on the redox behavior of hepatic microsomal cytochrome b-5 and its possible relationship to stearate desaturase.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 34, Issue:3

    Topics: Animals; Bromotrichloromethane; Chloroform; Cytochromes; Cytochromes b5; Fatty Acid Desaturases; Hydrocarbons, Halogenated; Kinetics; Microsomes, Liver; NAD; Oxidation-Reduction; Potassium Cyanide; Rats; Stearoyl-CoA Desaturase

1981
[Inhibition of the calcium-sequestering activity of liver microsomes in monobromotrichloromethane poisoning: preliminary studies on possible mechanisms].
    Bollettino della Societa italiana di biologia sperimentale, 1984, Jul-31, Volume: 60, Issue:7

    Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Bromotrichloromethane; Calcium; Cell Membrane Permeability; Chloroform; Microsomes, Liver; Rats

1984
On the mechanisms of the inhibition of calcium sequestering activity of liver microsomes in bromotrichloromethane intoxication.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bromotrichloromethane; Calcium; Calcium-Transporting ATPases; Chloroform; Energy Metabolism; Kinetics; Male; Microsomes, Liver; Oxalates; Oxalic Acid; Proteins; Rats; Rats, Inbred Strains

1984
Inhibition of Ca2+ sequestration in foetal liver microsomes by carbon tetrachloride and bromotrichloromethane.
    Biochemical pharmacology, 1984, Aug-15, Volume: 33, Issue:16

    Topics: Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Female; Fetus; Lipid Peroxides; Microsomes, Liver; Pregnancy; Rats; Rats, Inbred Strains

1984
Effect of halomethanes on intracellular calcium distribution in hepatocytes.
    Life sciences, 1984, Sep-10, Volume: 35, Issue:11

    Topics: Aminoquinolines; Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride Poisoning; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Compartmentation; Chloroform; Fluorescent Dyes; In Vitro Techniques; Liver; Rats

1984
Halomethane-induced inhibition of protein synthesis in isolated hepatocytes.
    Experimental and molecular pathology, 1984, Volume: 41, Issue:3

    Topics: Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride; Chloroform; Dose-Response Relationship, Drug; Hydrocarbons, Halogenated; Liver; Methane; Mixed Function Oxygenases; Protein Biosynthesis; Rats; Time Factors

1984
Correlations of in vitro and in vivo hepatotoxicity for five haloalkanes.
    Toxicology and applied pharmacology, 1983, Sep-15, Volume: 70, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Dose-Response Relationship, Drug; Hydrocarbons, Chlorinated; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Inbred Strains; Trichloroethanes

1983
Carbon tetrachloride and bromotrichloromethane toxicity. Dual role of covalent binding of metabolic cleavage products and lipid peroxidation in depression of microsomal calcium sequestration.
    Biochemical pharmacology, 1983, May-15, Volume: 32, Issue:10

    Topics: Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride; Chloroform; Depression, Chemical; Lipid Metabolism; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Promethazine; Rats; Rats, Inbred Strains

1983
Carbon tetrachloride, bromotrichloromethane and ethanol acute intoxication. New chemical evidence for lipid peroxidation in rat tissue microsomes.
    The Biochemical journal, 1983, Jun-15, Volume: 212, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Ethanol; Lipid Metabolism; Male; Microsomes; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Time Factors; Tissue Distribution

1983
Oxidation of carbon tetrachloride, bromotrichloromethane, and carbon tetrabromide by rat liver microsomes to electrophilic halogens.
    Life sciences, 1982, Jan-11, Volume: 30, Issue:2

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Hydrocarbons, Brominated; In Vitro Techniques; Male; Microsomes, Liver; Rats; Rats, Inbred Strains

1982
Evidence for aldehydes bound to liver microsomal protein following CCl4 or BrCCl3 poisoning.
    Biochimica et biophysica acta, 1982, May-13, Volume: 711, Issue:2

    Topics: Aldehydes; Animals; Bromotrichloromethane; Carbon Tetrachloride Poisoning; Chloroform; Intracellular Membranes; Male; Membrane Proteins; Microsomes, Liver; Phenylhydrazines; Rats; Spectrum Analysis

1982
Detection of carbonyl functions in phospholipids of liver microsomes in CCl4- and BrCCl3-poisoned rats.
    Biochimica et biophysica acta, 1982, Sep-14, Volume: 712, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride Poisoning; Chloroform; Kinetics; Lipid Peroxides; Male; Microsomes, Liver; Phenylhydrazines; Rats; Rats, Inbred Strains; Spectrophotometry

1982
Evaluation of a role for phosgene production in the hepatotoxic mechanism of action of carbon tetrachloride and bromotrichloromethane.
    Toxicology and applied pharmacology, 1982, Volume: 66, Issue:2

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Cysteine; Lipid Peroxides; Liver; Male; Microsomes, Liver; Phosgene; Rats; Rats, Inbred Strains

1982
Destruction of liver microsomal calcium pump activity by carbon tetrachloride and bromotrichloromethane.
    Biochemical pharmacology, 1981, Jan-15, Volume: 30, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Bromotrichloromethane; Calcium; Carbon Tetrachloride Poisoning; Chloroform; Male; Malondialdehyde; Microsomes, Liver; NADP; Rats

1981
Rapid depression of rat liver microsomal calcium pump activity after administration of carbon tetrachloride or bromotrichloromethane and lack of effect after ethanol.
    Toxicology and applied pharmacology, 1981, Jun-30, Volume: 59, Issue:2

    Topics: Animals; Biological Transport, Active; Bromotrichloromethane; Calcium; Carbon Tetrachloride; Chloroform; Ethanol; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Time Factors

1981
Production of volatile hydrocarbons by isolated hepatocytes: an in vitro model for lipid peroxidation studies.
    Toxicology and applied pharmacology, 1981, Volume: 60, Issue:1

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride Poisoning; Chloroform; Diet; Hydrocarbons; Lipid Peroxides; Liver; Male; Models, Biological; Rats; Rats, Inbred Strains; Vitamin E Deficiency; Volatilization

1981
Destruction of microsomal calcium pump activity: a possible secondary mechanism in BrCCl3 and CCl4 liver cell injury.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt A

    Topics: Animals; Bromotrichloromethane; Calcium; Carbon Tetrachloride Poisoning; Chloroform; Cytochrome P-450 Enzyme System; Iron; Kinetics; Lipid Peroxides; Liver; Malondialdehyde; Microsomes, Liver; Rats

1981
Suicidal inactivation of haemoproteins by reductive metabolites of halomethanes: a structure-activity relationship study.
    Toxicology, 1995, Jun-26, Volume: 100, Issue:1-3

    Topics: Animals; Binding, Competitive; Bromotrichloromethane; Carbon Tetrachloride; Chloroform; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dithionite; Hemoglobins; Humans; Hydrocarbons, Halogenated; Methemoglobin; Methylene Chloride; Microsomes, Liver; Oxidation-Reduction; Rats; Structure-Activity Relationship

1995
The interactive toxicity of CHCl3 and BrCCl3 in precision-cut rat liver slices.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 22, Issue:2

    Topics: Animals; Biomarkers; Bromotrichloromethane; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 Enzyme System; Drug Interactions; Electrolytes; Glucosephosphate Dehydrogenase; Glutathione; In Vitro Techniques; Isocitrate Dehydrogenase; Lipid Peroxidation; Liver; Male; Potassium; Rats; Rats, Sprague-Dawley

1994