chloroacetaldehyde and acrolein

chloroacetaldehyde has been researched along with acrolein in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (42.86)18.2507
2000's6 (42.86)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ansorge, S; Brandis, M; Mohrmann, M; Schmich, U; Schönfeld, B1
Allenbacher, A; Botzler, C; Issels, R; Meier, T; Mueller, E; Multhoff, G; Wiesnet, M1
Morris, ME; Springate, JE; Zamlauski-Tucker, MJ1
Costa, M; Gargas, M; Harris, M; Paustenbach, D; Zhitkovich, A1
Blaschke, G; Boos, J; Hohenlöchter, B; Jürgens, H; Rossi, R; Silies, H1
Manzano, RG; Twentyman, PR; Wright, KA1
Bunting, KD; Haynes, RL; Leone-Kabler, S; Szweda, L; Townsend, AJ; Wu, Y1
Balu, N; Colvin, ME; Colvin, OM; Dolan, ME; Gamcsik, MP; Ludeman, SM1
Springate, JE; Taub, M; Zaki, EL1
Benesic, A; Freudinger, R; Gekle, M; Gordjani, N; Kirchhoff, A; Schwerdt, G; Wollny, B1
Springate, J; Taub, M1
Dolan, ME; Hansen, RJ; Ludeman, SM; Paikoff, SJ; Pegg, AE1
Lau, V; MacAllister, SL; Martin-Brisac, N; O'Brien, PJ; Yang, K1
Chess-Williams, R; McDermott, C; Mills, KA1

Other Studies

14 other study(ies) available for chloroacetaldehyde and acrolein

ArticleYear
Toxicity of ifosfamide, cyclophosphamide and their metabolites in renal tubular cells in culture.
    Pediatric nephrology (Berlin, Germany), 1994, Volume: 8, Issue:2

    Topics: Acetaldehyde; Acrolein; Animals; Cell Line; Cells, Cultured; Cyclophosphamide; DNA; DNA Replication; Epithelial Cells; Epithelium; Ifosfamide; Kidney Tubules, Proximal; RNA; Swine; Thymidine; Uridine

1994
Ifosfamide induced depletion of glutathione in human peripheral blood lymphocytes and protection by mesna.
    Anti-cancer drugs, 1994, Volume: 5, Issue:4

    Topics: Acetaldehyde; Acrolein; Animals; CHO Cells; Cricetinae; Glutathione; Humans; Ifosfamide; Intracellular Fluid; Lymphocytes; Mesna

1994
Ifosfamide metabolite chloroacetaldehyde causes Fanconi syndrome in the perfused rat kidney.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:1

    Topics: Absorption; Acetaldehyde; Acrolein; Animals; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Fanconi Syndrome; Glucose; Ifosfamide; Kidney; Kidney Tubules, Proximal; Male; Organ Size; Phosphates; Prodrugs; Rats; Rats, Inbred Lew; Sodium; Sulfates

1994
DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells.
    Journal of toxicology and environmental health, 1997, Apr-11, Volume: 50, Issue:5

    Topics: Acetaldehyde; Acrolein; Aldehydes; Arsenates; Carcinogens; Cell Death; Cell Division; Cell Survival; Cross-Linking Reagents; DNA; DNA-Binding Proteins; Epoxy Compounds; Formaldehyde; Furaldehyde; Humans; Lymphoma; Methane; Mutagens; Nitroparaffins; Polymers; Tumor Cells, Cultured

1997
Excretion kinetics of ifosfamide side-chain metabolites in children on continuous and short-term infusion.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:5

    Topics: Acetaldehyde; Acrolein; Adolescent; Adult; Antineoplastic Agents, Alkylating; Child; Female; Humans; Ifosfamide; Infusions, Intravenous; Kidney; Male; Neoplasms; Phosphoramide Mustards

1998
Modulation by acrolein and chloroacetaldehyde of multidrug resistance mediated by the multidrug resistance-associated protein (MRP).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:8

    Topics: Acetaldehyde; Acrolein; ATP-Binding Cassette Transporters; Daunorubicin; Drug Resistance, Multiple; Glutathione; Humans; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured; Vinblastine

1996
Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells.
    Chemico-biological interactions, 2001, Jan-30, Volume: 130-132, Issue:1-3

    Topics: Acetaldehyde; Acrolein; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehydes; Alkylation; Animals; Apoptosis; Benzaldehydes; Cell Division; Cell Line; Cricetinae; Drug Resistance; Humans; Inactivation, Metabolic; Isoenzymes; Lipid Peroxidation; Proteins; Rats; Retinal Dehydrogenase; Transfection

2001
Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.
    Chemical research in toxicology, 2002, Volume: 15, Issue:3

    Topics: Acetaldehyde; Acrolein; Alkylation; Antineoplastic Agents, Alkylating; Cyclophosphamide; DNA Damage; Guanine; Humans; Leukemia

2002
Comparative toxicity of ifosfamide metabolites and protective effect of mesna and amifostine in cultured renal tubule cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2003, Volume: 17, Issue:4

    Topics: Acetaldehyde; Acrolein; Amifostine; Animals; Antineoplastic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Glucose; Glutathione; Ifosfamide; Kidney Tubules; Mesna; Neutral Red; Rabbits

2003
Chloroacetaldehyde- and acrolein-induced death of human proximal tubule cells.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:1

    Topics: Acetaldehyde; Acrolein; Cell Death; Cells, Cultured; Glutathione; Humans; Kidney Tubules, Proximal; Oxidation-Reduction

2006
Ifosfamide toxicity in cultured proximal renal tubule cells.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:3

    Topics: Acetaldehyde; Acrolein; Amifostine; Animals; Cell Culture Techniques; Cells, Cultured; Dose-Response Relationship, Drug; Ifosfamide; Inulin; Ion Transport; Kidney Tubules, Proximal; Male; Mesna; p-Aminohippuric Acid; Protective Agents; Rabbits; Tetraethylammonium

2007
Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.
    DNA repair, 2007, Aug-01, Volume: 6, Issue:8

    Topics: Acetaldehyde; Acrolein; Alkylating Agents; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclophosphamide; DNA Repair; Drug Resistance, Neoplasm; Ifosfamide; Mice; Mice, Knockout; Mutation; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Recombinant Proteins; Transfection; Transplantation, Heterologous

2007
Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity.
    Chemico-biological interactions, 2013, Feb-25, Volume: 202, Issue:1-3

    Topics: Acetaldehyde; Acrolein; Aldehyde Dehydrogenase; Animals; Biomarkers; Cell-Free System; Cyclophosphamide; Hepatocytes; Hydrogen Peroxide; Ifosfamide; Inactivation, Metabolic; Male; Microsomes, Liver; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin, Bovine

2013
Novel insights into the mechanism of cyclophosphamide-induced bladder toxicity: chloroacetaldehyde's contribution to urothelial dysfunction in vitro.
    Archives of toxicology, 2019, Volume: 93, Issue:11

    Topics: Acetaldehyde; Acrolein; Antineoplastic Agents, Alkylating; Cell Culture Techniques; Cell Line; Cell Survival; Cyclophosphamide; Epithelial Cells; Humans; Oxidative Stress; Reactive Oxygen Species; Urinary Bladder; Urothelium

2019