chlornaphazin has been researched along with chlorambucil in 2 studies
*Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) [MeSH]
*Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Leo, A; Panthananickal, A | 1 |
| Barnett, LB; Lewis, SE | 1 |
2 other study(ies) available for chlornaphazin and chlorambucil
| Article | Year |
|---|---|
Structure-activity relationships in antitumor aniline mustards.
Topics: Aniline Mustard; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Hydrolysis; Lethal Dose 50; Leukemia L1210; Leukemia, Experimental; Mice; Models, Biological; Nitrogen Mustard Compounds; Rats; Structure-Activity Relationship | 1978 |
Chlornaphazine and chlorambucil induce dominant lethal mutations in male mice.
Topics: Animals; Chlorambucil; Dose-Response Relationship, Drug; Female; Genes, Lethal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutagenicity Tests; Mutagens; Mutation; Nitrogen Mustard Compounds; Spermatids | 2003 |