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chlormethiazole and pentobarbital

chlormethiazole has been researched along with pentobarbital in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's7 (33.33)18.2507
2000's4 (19.05)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cross, AJ; De Souza, RJ; Green, AR; Murray, TK; Williams, JL1
Stone, TW1
Addae, JI; Stone, TW1
Absil, J; Buchel, L1
Bichler, KH; Maroske, D; Naber, K; Thaut, T1
Karppanen, H; Vapaatalo, H2
Decobert, M; Depoortere, H; Honoré, L1
Hillbom, ME; Hjelm-Jäger, M1
Kiianmaa, K; von Boguslawsky, K1
Colado, MI; Green, AR1
Kelder, D; Ross, SB1
Cross, AJ; Green, AR; Misra, A; Sandilands, A; Taylor, MJ1
Cross, AJ; Green, AR; Misra, A; Murray, TK; Snape, MF1
Simmonds, MA; Zhong, Y1
Järbe, TU; Swedberg, MD1
Green, AR; Hainsworth, AH; Lambert, DG; Nelson, RM1
Colado, MI; Esteban, B; Green, AR; O'Shea, E1
Thompson, SA; Usala, M; Wafford, KA; Whiting, PJ1

Reviews

1 review(s) available for chlormethiazole and pentobarbital

ArticleYear
Drug effects on the EEG of various species of laboratory animals.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine

1983

Other Studies

20 other study(ies) available for chlormethiazole and pentobarbital

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole.
    Neuropharmacology, 1992, Volume: 31, Issue:4

    Topics: Animals; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Diazepam; Dizocilpine Maleate; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Male; Methamphetamine; Neurotoxins; Pentobarbital; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Tyrosine 3-Monooxygenase

1992
Interactions of carbamazepine, chlormethiazole and pentobarbitone with adenosine on hippocampal slices.
    General pharmacology, 1988, Volume: 19, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Amino Acids; Animals; Carbamazepine; Chlormethiazole; Hippocampus; In Vitro Techniques; Iontophoresis; Kynurenic Acid; Male; Muscle Relaxants, Central; Pentobarbital; Rats; Receptors, Purinergic; Synapses

1988
Effects of anticonvulsants on responses to excitatory amino acids applied topically to rat cerebral cortex.
    General pharmacology, 1988, Volume: 19, Issue:3

    Topics: Administration, Topical; Amino Acids; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Chlormethiazole; Diazepam; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains

1988
[Effects of picrotoxin and pentetrazol on experimental sleep in the mouse].
    Archives des sciences physiologiques, 1974, Volume: 28, Issue:3

    Topics: Animals; Brain Chemistry; Chloral Hydrate; Chlormethiazole; Hexobarbital; Pentobarbital; Pentylenetetrazole; Picrotoxin; Sleep; Time Factors

1974
[Effect of chlormethiazole on kidney function. Experimental study in the dog].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:10

    Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Animals; Chlormethiazole; Dogs; Female; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Inulin; Kidney; Male; Pentobarbital; Regional Blood Flow; Urine

1971
Combined toxicity of ethanol with chlorpromazine, diazepam, chlormethiazole or pentobarbital in mice.
    Agents and actions, 1969, Volume: 1, Issue:2

    Topics: Animals; Chlormethiazole; Chlorpromazine; Diazepam; Drug Interactions; Ethanol; Injections, Intraperitoneal; Lethal Dose 50; Male; Mice; Pentobarbital; Time Factors

1969
Blood glucose, serum GOT and tissue catecholamines in rats after combined ethanol-tranquilizer administration.
    Agents and actions, 1970, Volume: 1, Issue:4

    Topics: Adrenal Glands; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Catecholamines; Chlormethiazole; Chlorpromazine; Diazepam; Drug Interactions; Epinephrine; Ethanol; Glutamates; Hyperglycemia; Male; Myocardium; Norepinephrine; Pentobarbital; Rats; Tranquilizing Agents

1970
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:1

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazole; Female; Humans; Male; Middle Aged; Oxazepam; Pentobarbital; Phenytoin; Psychoses, Alcoholic; Seizures; Substance Withdrawal Syndrome

1984
Behavioral effects following chronic treatment with clomethiazole, pentobarbital and diazepam in the rat.
    Substance and alcohol actions/misuse, 1981, Volume: 2, Issue:1

    Topics: Animals; Behavior, Animal; Chlormethiazole; Circadian Rhythm; Diazepam; Hypnotics and Sedatives; Male; Motor Activity; Pentobarbital; Rats; Rats, Inbred Strains; Seizures; Time Factors

1981
A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 4-Butyrolactone; Animals; Brain; Chlormethiazole; Designer Drugs; Dizocilpine Maleate; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Ondansetron; Pentobarbital; Rats; Serotonin

1994
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1993
Effect of chlormethiazole, dizocilpine and pentobarbital on harmaline-induced increase of cerebellar cyclic GMP and tremor.
    Psychopharmacology, 1993, Volume: 111, Issue:1

    Topics: Animals; Cerebellum; Chlormethiazole; Cyclic GMP; Dizocilpine Maleate; Harmaline; Male; Mice; Mice, Inbred Strains; Pentobarbital; Tremor

1993
A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor.
    Neuropharmacology, 1996, Volume: 35, Issue:9-10

    Topics: Allosteric Regulation; Animals; Behavior, Animal; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; GABA Modulators; Hypnotics and Sedatives; Male; Muscle Relaxation; Pentobarbital; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Sesterterpenes; Triazoles

1996
Interactions between loreclezole, chlormethiazole and pentobarbitone at GABA(A) receptors: functional and binding studies.
    British journal of pharmacology, 1997, Volume: 121, Issue:7

    Topics: Animals; Anticonvulsants; Bicuculline; Chlormethiazole; Flunitrazepam; In Vitro Techniques; Male; Medulla Oblongata; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles

1997
Discriminative stimulus functions of CNS sedative drugs assessed by drug versus drug discrimination procedures in gerbils.
    Psychopharmacology, 1998, Volume: 135, Issue:2

    Topics: Animals; Central Nervous System Depressants; Chlordiazepoxide; Chlormethiazole; Discrimination Learning; Ethanol; Gerbillinae; Male; Pentobarbital

1998
On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone.
    British journal of pharmacology, 2000, Volume: 130, Issue:5

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Chlormethiazole; Female; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A

2000
Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-induced neurodegeneration in rat brain.
    Psychopharmacology, 2001, Volume: 157, Issue:1

    Topics: Animals; Body Temperature; Chlormethiazole; Male; Methylamines; N-Methyl-3,4-methylenedioxyamphetamine; Neurodegenerative Diseases; Neuroprotective Agents; Pentobarbital; Rats; Receptors, GABA-A; Stereoisomerism; Thiazoles

2001
Activity of chlormethiazole at human recombinant GABA(A) and NMDA receptors.
    British journal of pharmacology, 2003, Volume: 140, Issue:6

    Topics: Animals; Chlormethiazole; DNA, Recombinant; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Pentobarbital; Propofol; Protein Subunits; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Xenopus laevis

2003