Page last updated: 2024-08-21

chlormethiazole and n-methylaspartate

chlormethiazole has been researched along with n-methylaspartate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sjölander, M; Thoren, P1
Cross, AJ; Green, AR; Snape, MF1
Czuczwar, SJ; Kleinrok, Z; Pilip, S; Turski, WA; Urbanska, EM1
Cross, AJ; Green, AR; Hewitt, KE; Misra, A; Snape, MF1
Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ1
Johansson, S; Luthman, J; Oberg, C; Radesäter, AC1
Luo, J; Pepperberg, DR; Qin, Z; Tavassoli, E; Thatcher, GR; Vandevrede, L; Yue, L1

Other Studies

7 other study(ies) available for chlormethiazole and n-methylaspartate

ArticleYear
Chlormethiazole attenuates the derangement of sensory evoked potential (SEP) induced by ICV administration of NMDA.
    Psychopharmacology, 1993, Volume: 111, Issue:2

    Topics: Animals; Blood Pressure; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Electroencephalography; Evoked Potentials, Somatosensory; Heart Rate; Injections, Intraventricular; N-Methylaspartate; Rats

1993
Chlormethiazole antagonises seizures induced by N-methyl-DL-aspartate without interacting with the NMDA receptor complex.
    Psychopharmacology, 1993, Volume: 112, Issue:4

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Membranes; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures

1993
Chlormethiazole anticonvulsive efficacy diminished by N-methyl-D-aspartate but not kainate in mice.
    European journal of pharmacology, 1998, Mar-26, Volume: 345, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Chlormethiazole; Electroshock; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Male; Mice; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures

1998
An investigation of the possible interaction of clomethiazole with glutamate and ion channel sites as an explanation of its neuroprotective activity.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:2

    Topics: Alanine; Animals; Chlormethiazole; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Ion Channels; Male; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Rats; Receptors, Glutamate

1998
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine

2000
The vitamin-E analog trolox and the NMDA antagonist MK-801 protect pyramidal neurons in hippocampal slice cultures from IL-1beta-induced neurodegeneration.
    Neurotoxicity research, 2003, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Antioxidants; Chlormethiazole; Chromans; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Modulators; Hippocampus; Immunohistochemistry; Interleukin-1; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2003
Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation.
    British journal of pharmacology, 2014, Volume: 171, Issue:2

    Topics: Animals; Biological Availability; Brain; Calcium; Cell Hypoxia; Chlormethiazole; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Oocytes; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus laevis

2014