chlormethiazole has been researched along with gamma-aminobutyric acid in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hales, TG; Lambert, JJ | 1 |
| Baldwin, HA; Cross, AJ; Green, AR; Jones, JA | 1 |
| Enjalbert, A; Kordon, C; Lechat, P; Lloyd, KG; Paillard, JJ; Thuret, F; Vincens, M | 1 |
| Bowen, DM; Cross, AJ; Francis, PT; Green, AR; Robinson, TN; Stirling, JM | 1 |
| Simmonds, MA; Turner, JP | 1 |
| Ogren, SO | 1 |
| Gent, JP; Wacey, TA | 1 |
| Graham, DI; MacGregor, DG; Stone, TW | 1 |
| Banger, M; Bonnet, U; Gastpar, M; Kowalski, T; Leweke, FM; Maschke, M | 1 |
| Green, AR; Hainsworth, AH; Jackson, DM | 1 |
| Stone, TW | 1 |
| Green, AR; Hainsworth, AH; Lambert, DG; Nelson, RM | 1 |
| Empson, RM; Gee, VJ; Newberry, NR; Sheardown, MJ | 1 |
| Cross, AJ; Gabrielsson, J; Green, AR; Hainsworth, AH; Jones, JA; Lambert, DG; Murray, TK; Nelson, RM; Richards, DA | 1 |
| Green, AR; Hainsworth, AH; Nelson, RM | 1 |
| Thompson, SA; Usala, M; Wafford, KA; Whiting, PJ | 1 |
| Green, AC; Harrison, PK; Sheridan, RD; Tattersall, JE | 1 |
| Carlsson, KC; Hooker, AC; Karlsson, MO; Savić, RM | 1 |
| Bonnet, U; Hamzavi Abedi, R; Scherbaum, N; Specka, M; Wiltfang, J | 1 |
| Luo, J; Pepperberg, DR; Qin, Z; Tavassoli, E; Thatcher, GR; Vandevrede, L; Yue, L | 1 |
| Liu, J; Wang, LN; Zhang, J | 1 |
3 review(s) available for chlormethiazole and gamma-aminobutyric acid
| Article | Year |
|---|---|
Potentiators of responses to activation of gamma-aminobutyric acid (GABAA) receptors.
Topics: Animals; Barbiturates; Carbolines; Chlorides; Chlormethiazole; Ethanol; gamma-Aminobutyric Acid; Ketamine; Receptors, GABA-A; Steroids | 1987 |
GABA potentiation: a logical pharmacological approach for the treatment of acute ischaemic stroke.
Topics: Acute Disease; Animals; Brain; Brain Ischemia; Chlormethiazole; GABA Agonists; gamma-Aminobutyric Acid; Humans; Muscimol; Neuroprotective Agents; Receptors, GABA-A | 2000 |
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
Topics: Acute Disease; Chlormethiazole; Diazepam; Disorders of Excessive Somnolence; GABA Agonists; gamma-Aminobutyric Acid; Humans; Neuroprotective Agents; Randomized Controlled Trials as Topic; Rhinitis; Stroke | 2018 |
1 trial(s) available for chlormethiazole and gamma-aminobutyric acid
| Article | Year |
|---|---|
Treatment of alcohol withdrawal syndrome with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Central Nervous System Depressants; Chlormethiazole; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome | 1999 |
17 other study(ies) available for chlormethiazole and gamma-aminobutyric acid
| Article | Year |
|---|---|
Modulation of GABAA and glycine receptors by chlormethiazole.
Topics: Animals; Cattle; Cells, Cultured; Chlormethiazole; Chromaffin System; Drug Synergism; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Glycine; Mice; Neurons; Receptors, GABA-A | 1992 |
Neuroprotective activity of chlormethiazole following transient forebrain ischaemia in the gerbil.
Topics: Animals; Body Temperature; Chlormethiazole; Drug Synergism; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Prosencephalon | 1991 |
Evidence that clomethiazole interacts with the macromolecular GABA A-receptor complex in the central nervous system and in the anterior pituitary gland.
Topics: Animals; Central Nervous System; Chlormethiazole; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Indicators and Reagents; Male; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1989 |
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
Topics: Animals; Baclofen; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; CLC-2 Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A | 1989 |
Chlormethiazole--mode of action.
Topics: Animals; Brain; Chlormethiazole; Convulsants; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Mice; Neural Inhibition; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin | 1986 |
The effects of chlormethiazole on single unit activity in rat brain; interactions with inhibitory and excitatory neurotransmitters.
Topics: Acetylcholine; Animals; Brain; Chlormethiazole; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Muscimol; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1983 |
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Entorhinal Cortex; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gliosis; Hippocampus; Isoquinolines; Kainic Acid; Male; Muscimol; Neurons; Neuroprotective Agents; Neurotoxins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines | 1997 |
Effects of clomethiazole on spreading depression in the rat hippocampal slice.
Topics: Action Potentials; Animals; Cell Hypoxia; Chlormethiazole; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neuroprotective Agents; Potassium; Rats; Rats, Wistar | 2000 |
On the regulation of ischaemia-induced glutamate efflux from rat cortex by GABA; in vitro studies with GABA, clomethiazole and pentobarbitone.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chlormethiazole; Female; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Pentobarbital; Rats; Rats, Wistar; Receptors, GABA-A | 2000 |
Chlormethiazole inhibits epileptiform activity by potentiating GABA(A) receptor function.
Topics: Action Potentials; Animals; Bicuculline; Cerebral Cortex; Chlormethiazole; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Valine | 2000 |
Neuroprotective efficacy of AR-A008055, a clomethiazole analogue, in a global model of acute ischaemic stroke and its effect on ischaemia-induced glutamate and GABA efflux in vitro.
Topics: Animals; Brain Ischemia; Chlormethiazole; Female; gamma-Aminobutyric Acid; Gerbillinae; Glutamic Acid; Hippocampus; Male; Methylamines; Neuroprotective Agents; Rats; Rats, Wistar; Stroke; Thiazoles | 2001 |
Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors.
Topics: Animals; Chlormethiazole; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Receptors, GABA-A; Recombinant Proteins | 2002 |
Activity of chlormethiazole at human recombinant GABA(A) and NMDA receptors.
Topics: Animals; Chlormethiazole; DNA, Recombinant; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Oocytes; Pentobarbital; Propofol; Protein Subunits; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2003 |
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus.
Topics: Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Chlormethiazole; Clozapine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Levetiracetam; Male; Phenylcarbamates; Phenylenediamines; Piracetam; Propylene Glycols; Soman; Topiramate | 2005 |
Modeling subpopulations with the $MIXTURE subroutine in NONMEM: finding the individual probability of belonging to a subpopulation for the use in model analysis and improved decision making.
Topics: Algorithms; Anticonvulsants; Chlormethiazole; Computer Simulation; Decision Making; Decision Support Techniques; Epilepsy; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Likelihood Functions; Monitoring, Physiologic; Nonlinear Dynamics; Patients; Poisson Distribution; Pregabalin; Probability; Randomized Controlled Trials as Topic; Software; Stroke | 2009 |
Severe protracted alcohol withdrawal syndrome: prevalence and pharmacological treatment at an inpatient detoxification unit--a naturalistic study.
Topics: Adult; Aged; Alcoholism; Amines; Anticonvulsants; Chlormethiazole; Clonazepam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Inpatients; Male; Middle Aged; Prevalence; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome | 2009 |
Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation.
Topics: Animals; Biological Availability; Brain; Calcium; Cell Hypoxia; Chlormethiazole; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Oocytes; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus laevis | 2014 |