Page last updated: 2024-08-21

chlormethiazole and dizocilpine maleate

chlormethiazole has been researched along with dizocilpine maleate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (68.75)18.2507
2000's4 (25.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cross, AJ; De Souza, RJ; Green, AR; Murray, TK; Williams, JL1
Colado, MI; Green, AR; Snape, MF1
Colado, MI; Green, AR1
Green, AR; Hewitt, KE1
Colado, MI; Green, AR; Murray, TK1
Cross, AJ; Green, AR; Misra, A; Sandilands, A; Taylor, MJ1
Sjölander, M; Thoren, P1
Cross, AJ; Green, AR; Snape, MF1
Baldwin, HA; Colado, MI; De Souza, RJ; Green, AR; Murray, TK1
Graham, DI; MacGregor, DG; Stone, TW1
Cross, AJ; Green, AR; Hewitt, KE; Misra, A; Snape, MF1
Camarero, J; Colado, MI; Elliott, JM; Esteban, B; Green, AR; Mechan, AO; Sanchez, V1
Johansson, S; Luthman, J; Oberg, C; Radesäter, AC1
Forsberg, T; Gabrielsson, J; Martinsson, S; Pozarek, S; Ross, SB; Visser, SA1
Beninger, RJ; Boegman, RJ; Forsyth, JK; Jhamandas, K; Reynolds, JN; Van Adel, M1
Addae, JI; Ali, N; Stone, TW1

Other Studies

16 other study(ies) available for chlormethiazole and dizocilpine maleate

ArticleYear
The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole.
    Neuropharmacology, 1992, Volume: 31, Issue:4

    Topics: Animals; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Diazepam; Dizocilpine Maleate; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Male; Methamphetamine; Neurotoxins; Pentobarbital; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Tyrosine 3-Monooxygenase

1992
Chlormethiazole and dizocilpine block the behavioural, but not the neurotoxic effects of 5,7-dihydroxytryptamine in mice.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Brain; Chlormethiazole; Dizocilpine Maleate; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Seizures; Serotonin

1994
A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 4-Butyrolactone; Animals; Brain; Chlormethiazole; Designer Drugs; Dizocilpine Maleate; Dopamine; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Ondansetron; Pentobarbital; Rats; Serotonin

1994
Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats.
    Neuropharmacology, 1994, Volume: 33, Issue:12

    Topics: Animals; Chlormethiazole; Dizocilpine Maleate; Haloperidol; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin

1994
5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Rats; Serotonin

1993
Effect of chlormethiazole, dizocilpine and pentobarbital on harmaline-induced increase of cerebellar cyclic GMP and tremor.
    Psychopharmacology, 1993, Volume: 111, Issue:1

    Topics: Animals; Cerebellum; Chlormethiazole; Cyclic GMP; Dizocilpine Maleate; Harmaline; Male; Mice; Mice, Inbred Strains; Pentobarbital; Tremor

1993
Chlormethiazole attenuates the derangement of sensory evoked potential (SEP) induced by ICV administration of NMDA.
    Psychopharmacology, 1993, Volume: 111, Issue:2

    Topics: Animals; Blood Pressure; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Electroencephalography; Evoked Potentials, Somatosensory; Heart Rate; Injections, Intraventricular; N-Methylaspartate; Rats

1993
Chlormethiazole antagonises seizures induced by N-methyl-DL-aspartate without interacting with the NMDA receptor complex.
    Psychopharmacology, 1993, Volume: 112, Issue:4

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Membranes; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures

1993
Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Cerebral Cortex; Chlormethiazole; Corpus Striatum; Dialysis; Dizocilpine Maleate; Dopamine; Hippocampus; Homovanillic Acid; Male; Methamphetamine; Potassium; Rats

1993
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
    Experimental neurology, 1997, Volume: 148, Issue:1

    Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug Therapy, Combination; Entorhinal Cortex; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gliosis; Hippocampus; Isoquinolines; Kainic Acid; Male; Muscimol; Neurons; Neuroprotective Agents; Neurotoxins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Xanthines

1997
An investigation of the possible interaction of clomethiazole with glutamate and ion channel sites as an explanation of its neuroprotective activity.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:2

    Topics: Alanine; Animals; Chlormethiazole; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Ion Channels; Male; N-Methylaspartate; Neuroprotective Agents; Phosphatidylinositols; Rats; Receptors, Glutamate

1998
A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Animals; Chlormethiazole; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fever; Free Radicals; Hydroxybenzoates; Injections, Intraperitoneal; Male; Mice; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Nitrogen Oxides; Pyridines; Salicylic Acid

2001
The vitamin-E analog trolox and the NMDA antagonist MK-801 protect pyramidal neurons in hippocampal slice cultures from IL-1beta-induced neurodegeneration.
    Neurotoxicity research, 2003, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Antioxidants; Chlormethiazole; Chromans; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Modulators; Hippocampus; Immunohistochemistry; Interleukin-1; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2003
Rapid and long-lasting tolerance to clomethiazole-induced hypothermia in the rat.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; Hypothermia; Injections, Subcutaneous; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors

2005
Subchronic MK-801 behavioural deficits in rats: partial reversal by the novel nitrate GT 1061.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4

    Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Chlormethiazole; Cognition Disorders; Data Interpretation, Statistical; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Male; Maze Learning; Motor Activity; Nitrates; Rats; Rats, Sprague-Dawley; Reversal Learning

2009
Effects of AMPA and clomethiazole on spreading depression cycles in the rat neocortex in vivo.
    European journal of pharmacology, 2011, Feb-25, Volume: 653, Issue:1-3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chlormethiazole; Cortical Spreading Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; GABA Modulators; Male; Neocortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

2011