chlorine has been researched along with wortmannin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abreu, MT; Arnold, ET; Barrett, KE; Chow, JY | 1 |
| Barrett, KE; Bertelsen, LS; Keely, SJ | 1 |
| Dubyak, G; Guo, X; Hopfer, U; Laboisse, C; Landis, D; Martin, K; Merlin, D | 1 |
| Barrett, KE; Keely, SJ; Traynor-Kaplan, AE; Uribe, JM | 1 |
| Guo, XW; Hopfer, U; Laboisse, C; Merlin, D | 1 |
| Feranchak, AP; Fitz, JG; Roman, RM; Schwiebert, EM | 1 |
| Doctor, RB; Feranchak, AP; Fitz, JG; Roman, RM; Salter, KD; Toker, A | 1 |
| Ohno, R; Takahashi, R; Tran, QK; Watanabe, H; Zhang, XX | 1 |
| Conner, TD; Dickson, JL; Ecay, TW | 2 |
| Barrett, KE; Chow, JY; Uribe, JM | 1 |
| Barrett, KE; Calandrella, S; Chang, N; Keely, SJ; Uribe, JM | 1 |
| Alrefai, WA; Dudeja, PK; Gill, RK; Ramaswamy, K; Saksena, S; Syed, IA; Tyagi, S | 1 |
| Buresi, MC; Buret, AG; Hollenberg, MD; MacNaughton, WK | 1 |
| Cassai, N; Charney, AN; Egnor, RW; Henner, D; Rashid, H; Sidhu, GS | 1 |
| Adragna, NC; Lauf, PK; Zhang, J | 1 |
| Barrett, KE; Hoda, MR; Keely, SJ; McCole, DF; Scharl, M | 1 |
| Dong, J; Fang, H; He, S; Huang, K; Kushwaha, KK; Li, D; Lin, J; Mohabeer, N; Su, Y; Wang, B; Wu, C | 1 |
18 other study(ies) available for chlorine and wortmannin
| Article | Year |
|---|---|
Phosphatidylinositol 3-kinase-dependent pathways oppose Fas-induced apoptosis and limit chloride secretion in human intestinal epithelial cells. Implications for inflammatory diarrheal states.
Topics: 3T3 Cells; Actins; Androstadienes; Animals; Apoptosis; Blotting, Western; Caspases; Cell Adhesion; Cell Line; Cells, Cultured; Chlorine; Chromones; Cross-Linking Reagents; Cytoskeletal Proteins; Desmoplakins; Diarrhea; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; fas Receptor; Humans; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoproteins; Signal Transduction; Time Factors; Wortmannin; Zonula Occludens-1 Protein | 2001 |
Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.
Topics: Androstadienes; Blotting, Western; Cell Line; Chlorides; Chlorine; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; GTP-Binding Protein alpha Subunits, Gs; Humans; Ions; Isoquinolines; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Quinazolines; Sulfonamides; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Vasoactive Intestinal Peptide; Wortmannin | 2004 |
Recruitment of purinergically stimulated Cl- channels from granule membrane to plasma membrane.
Topics: Actins; Adenosine Triphosphate; Androstadienes; Cell Membrane; Chloride Channels; Chlorides; Cytoplasmic Granules; Enzyme Inhibitors; Humans; Intracellular Membranes; Microscopy, Electron; Mucins; Phalloidine; Polymers; Purines; Receptors, Purinergic; Tumor Cells, Cultured; Wortmannin | 1996 |
Phosphatidylinositol 3-kinase mediates the inhibitory effect of epidermal growth factor on calcium-dependent chloride secretion.
Topics: Androstadienes; Calcium; Carbachol; Catalysis; Cell Line; Chlorides; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Lipids; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Wortmannin | 1996 |
Purinergic agonists, but not cAMP, stimulate coupled granule fusion and Cl- conductance in HT29-Cl.16E.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Androstadienes; Cell Differentiation; Cell Division; Chloride Channels; Chlorides; Clone Cells; Colforsin; Cyclic AMP; Cytoplasmic Granules; Enzyme Inhibitors; Epithelium; HT29 Cells; Humans; Intracellular Membranes; Membrane Fusion; Membrane Potentials; Patch-Clamp Techniques; Purinergic Agonists; Signal Transduction; Wortmannin | 1997 |
Phosphatidylinositol 3-kinase contributes to cell volume regulation through effects on ATP release.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Membrane Permeability; Cell Size; Chlorides; Chromones; Electrophysiology; Enzyme Inhibitors; Hypotonic Solutions; Ion Channels; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Tumor Cells, Cultured; Wortmannin | 1998 |
The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Bile Duct Neoplasms; Bile Ducts; Bile Ducts, Intrahepatic; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cholangiocarcinoma; Chromones; Enzyme Inhibitors; Epithelial Cells; Homeostasis; Humans; Hypotonic Solutions; Kinetics; Membrane Potentials; Morpholines; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction; Tumor Cells, Cultured; Wortmannin | 1999 |
Involvement of myosin light-chain kinase in chloride-sensitive Ca2+ influx in porcine aortic endothelial cells.
Topics: Androstadienes; Animals; Aorta; Azepines; Bradykinin; Calcium; Calcium Channel Blockers; Carrier Proteins; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Furosemide; Myosin-Light-Chain Kinase; ortho-Aminobenzoates; Sodium-Potassium-Chloride Symporters; Swine; Thapsigargin; Wortmannin | 1999 |
Inhibition of phosphatidylinositol 3-kinase does not alter forskolin-stimulated Cl(-) secretion by T84 cells.
Topics: Androstadienes; Cell Compartmentation; Cell Line; Cell Membrane; Chlorides; Chromones; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Endocytosis; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Ion Transport; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Thapsigargin; Wortmannin | 2000 |
A role for protein kinase cepsilon in the inhibitory effect of epidermal growth factor on calcium-stimulated chloride secretion in human colonic epithelial cells.
Topics: Androstadienes; Calcium; Carbachol; Chlorides; Chromones; Colon; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Indoles; Intestinal Mucosa; Isoenzymes; Kinetics; Morpholines; Oligodeoxyribonucleotides, Antisense; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Kinase C-epsilon; RNA, Messenger; Wortmannin | 2000 |
Wortmannin inhibition of forskolin-stimulated chloride secretion by T84 cells.
Topics: Androstadienes; Animals; Apigenin; Carrier Proteins; Cell Line; Chlorides; Colforsin; Electrochemistry; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinases; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Wortmannin | 2000 |
Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells.
Topics: Androstadienes; Carbachol; Cells, Cultured; Chlorides; Cholinergic Agonists; Chromones; Colon; Diabetes Mellitus; Diarrhea; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Intestinal Mucosa; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Thapsigargin; Tyrosine; Wortmannin | 2001 |
Inhibition of apical Cl-/OH- exchange activity in Caco-2 cells by phorbol esters is mediated by PKCepsilon.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Androstadienes; Biological Transport; Caco-2 Cells; Carcinogens; Chloride-Bicarbonate Antiporters; Chlorides; Chromones; Enzyme Inhibitors; Humans; Insulin Receptor Substrate Proteins; Isoenzymes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Kinase C; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Wortmannin | 2002 |
Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
Topics: Androstadienes; Butadienes; Cell Line; Chlorides; Epithelial Cells; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Nitriles; Nitrobenzenes; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Tyrphostins; Wortmannin | 2002 |
Acid-base effects on intestinal Cl- absorption and vesicular trafficking.
Topics: Absorption; Acid-Base Equilibrium; Androstadienes; Animals; Anion Exchange Protein 1, Erythrocyte; Blotting, Western; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Chlorides; Colon; Endocytosis; Exocytosis; Hydrogen-Ion Concentration; Ileum; Immunoenzyme Techniques; In Vitro Techniques; Male; Methazolamide; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Transport Vesicles; Wortmannin | 2004 |
PDGF activates K-Cl cotransport through phosphoinositide 3-kinase and protein phosphatase-1 in primary cultures of vascular smooth muscle cells.
Topics: Androstadienes; Animals; Becaplermin; Cells, Cultured; Chlorides; Chromones; Cyclosporine; Flavonoids; K Cl- Cotransporters; Marine Toxins; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Okadaic Acid; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Platelet-Derived Growth Factor; Potassium; Protein Phosphatase 1; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Symporters; Vanadates; Wortmannin | 2005 |
Apical leptin induces chloride secretion by intestinal epithelial cells and in a rat model of acute chemotherapy-induced colitis.
Topics: Androstadienes; Animals; Carbachol; Cell Line; Chlorides; Colforsin; Enterocolitis; Epithelial Cells; Flavonoids; Humans; Leptin; Male; MAP Kinase Signaling System; Methotrexate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Wortmannin | 2010 |
Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway.
Topics: Androstadienes; Animals; Blood Platelets; Carotid Artery Thrombosis; Chlorides; Chromones; Cytokines; Disease Models, Animal; Ferric Compounds; Humans; Immunoglobulins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; P-Selectin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Proto-Oncogene Proteins c-akt; Receptors, Cytokine; Signal Transduction; Thymic Stromal Lymphopoietin; Wortmannin | 2015 |