chlorine has been researched along with quinazolines in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (26.47) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 12 (35.29) | 29.6817 |
| 2010's | 8 (23.53) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Bishop, JA; Calvert, AH; Chambers, P; Hayter, AJ; Hughes, LR; Jackman, AL; Marsham, PR; O'Connor, BM | 1 |
| Amand, RS; Chen, KK; Modest, EJ; Rosowsky, A | 1 |
| Barrett, KE; Bertelsen, LS; Keely, SJ | 1 |
| Gao, M; Lola, CM; Miller, KD; Sledge, GW; Wang, M; Zheng, QH | 1 |
| Carter, DB; Hamilton, BJ; Hansen, HC; Im, HK; Im, WB; Kristiansen, M; Petke, JD; Pregenzer, JF; Von Voigtlander, PF | 1 |
| Araki, T; Hara, H; Kato, H; Kogure, K; Onodera, H | 1 |
| Materson, BJ; Oster, JR; Perez-Stable, EC | 1 |
| Bailey, K; Barkin, JS; Hotchkiss, JL; Materson, BJ; Perez-Stable, EC; Rietberg, BH | 1 |
| Belair, E; Borrelli, A; Kaiser, F; Yelnosky, J | 1 |
| Belair, EJ | 1 |
| Hillenbrand, P; Sherlock, S | 1 |
| Hagen, HE; Roth, HJ | 1 |
| Katz, U; Nagel, W; Shalitin, Y | 1 |
| Barrett, KE; Keely, SJ; Uribe, JM | 1 |
| Barrett, KE; Calandrella, SO; Keely, SJ | 1 |
| Assaraf, YG; Drori, S; Jansen, G; Mauritz, R; Peters, GJ | 1 |
| Barrett, KE; McCole, DF; Uribe, JM | 1 |
| Buresi, MC; Buret, AG; Hollenberg, MD; MacNaughton, WK | 1 |
| SANDLER, G | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Roy, AD; Roy, R; Subramanian, A | 1 |
| Cruz-Rangel, S; Islas, LD; Lezama, RA; Pasantes-Morales, H; Ramos-Mandujano, G; Vázquez-Juárez, E | 1 |
| Hu, Z; Wu, D | 1 |
| Portela-Cubillo, F; Scott, JS; Walton, JC | 1 |
| Chen, X; Li, J; Li, Q; Ma, S; Shi, D; Tang, J; Zhang, Q | 1 |
| Asano, J; Dejima, K; Hama, T; Hisa, Y; Iwasaki, Y; Marunaka, Y; Miyazaki, H; Nakajima, K; Niisato, N; Yasuda, M | 1 |
| Donnellan, F; Geoghegan, P; Harvey, BJ; Keating, N; Keely, SJ; Murray, FE | 1 |
| Chen, Z; Li, S; Wu, Y; Xie, H; Zhu, J | 1 |
| Caci, E; Esposito, AI; Galietta, LJ; Pedemonte, N; Pfeffer, U; Sondo, E; Tomati, V | 1 |
| Aiken, M; Nauseef, WM; Painter, RG; Reiser, J; Song, K; Stanton, BA; Wang, G; Zhou, Y | 1 |
| Daniels, DL; Davis-Ward, RG; Izydore, RA; Jones, JT; Kpakima, FF; Mogesa, B; Spaulding-Phifer, ST; Swain, IN | 1 |
| Bodiga, S; Bodiga, VL; Thokala, S; Vemuri, PK | 1 |
| Abuelizz, HA; Al-Salahi, R; Almehizia, AA; Bakheit, AH; Herqash, R; Marzouk, M; Taie, HAA | 1 |
| Fülöp, F; Haukka, M; Palkó, M; Said, AI | 1 |
2 trial(s) available for chlorine and quinazolines
| Article | Year |
|---|---|
Antihypertensive effects of metolazone (zaroxolyn).
Topics: Adult; Aged; Antihypertensive Agents; Bicarbonates; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Calcium; Chlorides; Clinical Trials as Topic; Creatinine; Diuretics; Drug Evaluation; Humans; Hypertension; Middle Aged; Placebos; Quinazolines; Sulfonamides; Uric Acid | 1974 |
Cystic fibrosis transmembrane conductance regulator recruitment to phagosomes in neutrophils.
Topics: Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Hydrogen Peroxide; Hypochlorous Acid; Ion Transport; Lysosomal Membrane Proteins; NADPH Oxidases; Neutrophils; Phagosomes; Piperazines; Quinazolines | 2013 |
32 other study(ies) available for chlorine and quinazolines
| Article | Year |
|---|---|
Quinazoline antifolate thymidylate synthase inhibitors: nitrogen, oxygen, sulfur, and chlorine substituents in the C2 position.
Topics: Animals; Chemical Phenomena; Chemistry; Chlorine; Folic Acid Antagonists; Leukemia L1210; Mice; Nitrogen; Oxygen; Quinazolines; Structure-Activity Relationship; Sulfur; Thymidylate Synthase; Tumor Cells, Cultured | 1989 |
Chemical and biological studies on 1,2-dihydro-s-triazines. 18. Synthesis of 1-(5,6- and 5,7-dichloro-2-naphthyl) derivatives and related compounds as candidate antimalarial and antitumor agents.
Topics: Animals; Antimalarials; Antineoplastic Agents; Ascites; Biguanides; Carcinoma, Squamous Cell; Cells; Chlorine; Humans; Leukemia, Experimental; Mice; Mice, Inbred DBA; Naphthalenes; Neoplasm Transplantation; Plasmodium; Plasmodium berghei; Quinazolines; Streptococcus; Transplantation, Homologous; Triazines | 1973 |
Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.
Topics: Androstadienes; Blotting, Western; Cell Line; Chlorides; Chlorine; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; GTP-Binding Protein alpha Subunits, Gs; Humans; Ions; Isoquinolines; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Quinazolines; Sulfonamides; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Vasoactive Intestinal Peptide; Wortmannin | 2004 |
Radiosynthesis of [11C]Vandetanib and [11C]chloro-Vandetanib as new potential PET agents for imaging of VEGFR in cancer.
Topics: Carbon Radioisotopes; Chlorine; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Neoplasms; Piperidines; Positron-Emission Tomography; Quinazolines; Radiopharmaceuticals; Receptors, Vascular Endothelial Growth Factor | 2011 |
Differential potentiation of GABAA receptor function by two stereoisomers of diimidazoquinazoline analogues.
Topics: Binding Sites; Cell Line; Chlorides; Computer Simulation; Electrophysiology; Humans; Imidazoles; Quinazolines; Receptors, GABA-A; Stereoisomerism; Transfection | 1992 |
Involvement of lipid peroxidation and inhibitory mechanisms on ischemic neuronal damage in gerbil hippocampus: quantitative autoradiographic studies on second messenger and neurotransmitter systems.
Topics: Adenosine; Animals; Autoradiography; Body Temperature; Brain Ischemia; Calcium Channels; Chlorides; Colforsin; Gerbillinae; Hippocampus; Inositol 1,4,5-Trisphosphate; Ion Channels; Lipid Peroxidation; Male; Neurons; Neurotransmitter Agents; Pentobarbital; Phorbol 12,13-Dibutyrate; Quinazolines; Quinuclidinyl Benzilate; Receptors, GABA-A; Second Messenger Systems | 1991 |
Oral metolazone: effects on urine composition in water-loaded normal man.
Topics: Bicarbonates; Blood Chemical Analysis; Calcium; Chlorides; Creatine; Diuretics; Dose-Response Relationship, Drug; Furosemide; Humans; Hydrochlorothiazide; Ketones; Kidney Tubules, Proximal; Kinetics; Magnesium; Male; Mathematics; Natriuresis; Osmolar Concentration; Phosphates; Potassium; Quinazolines; Sodium; Stimulation, Chemical; Sulfonamides; Urination | 1972 |
Interaction studies with metolazone, heparin and protamine sulfate.
Topics: Animals; Blood Coagulation; Chlorides; Diuresis; Diuretics; Dogs; Drug Interactions; Heparin; Heparin Antagonists; Natriuresis; Protamines; Quinazolines; Sulfonamides; Time Factors | 1973 |
The renal pharmacology of metolazone, 2-methyl-3-O-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone.
Topics: Acidosis; Alkalosis; Animals; Chlorides; Diuretics; Dogs; Drug Compounding; Female; Furosemide; Haplorhini; Hydrogen-Ion Concentration; Ketones; Kidney; Kinetics; Macaca; Male; Natriuresis; Potassium; Quinazolines; Rats; Rats, Inbred Strains; Sodium; Spectrum Analysis; Sulfonamides; Water; Water-Electrolyte Balance | 1971 |
Use of metolazone in the treatment of ascites due to liver disease.
Topics: Adult; Ascites; Chlorides; Chronic Disease; Diuretics; Female; Hepatic Encephalopathy; Humans; Hypokalemia; Hyponatremia; Ketones; Liver Diseases; Male; Middle Aged; Nitrogen; Pyrazines; Quinazolines; Spironolactone; Sulfonamides; Uremia | 1971 |
[Aminomethylation of enamines of cyclic beta-dicarbonyl compounds].
Topics: Amines; Benzyl Compounds; Chemical Phenomena; Chemistry; Chlorides; Formaldehyde; Methods; Methylation; Piperidines; Quinazolines; Resorcinols; Spectrum Analysis | 1971 |
Effects of aminoperimidine on electrolyte transport across amphibian skin.
Topics: Amiloride; Animals; Benzimidazoles; Bufonidae; Chlorides; Cyclic AMP; Dose-Response Relationship, Drug; Electric Conductivity; Guanidines; In Vitro Techniques; Ion Transport; Microelectrodes; Patch-Clamp Techniques; Quinazolines; Rana esculenta; Skin; Sodium | 1998 |
Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Chlorides; Colon; ErbB Receptors; GRB2 Adaptor Protein; Intestinal Mucosa; Phosphorylation; Protein Binding; Protein Kinase C; Proteins; Quinazolines; Receptor, Muscarinic M3; Receptors, Muscarinic; Shc Signaling Adaptor Proteins; Signal Transduction; Transcriptional Activation; Tyrphostins | 1998 |
Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src).
Topics: Calcium; Carbachol; Cell Line; Chlorides; Colon; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; Fluphenazine; Focal Adhesion Kinase 2; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Signal Transduction; Thapsigargin; Time Factors; Transcriptional Activation; Tyrphostins | 2000 |
Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Blotting, Northern; Blotting, Southern; Blotting, Western; Carrier Proteins; Cell Division; Cell Membrane; Chlorides; DNA Mutational Analysis; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Exons; Folic Acid; Folic Acid Antagonists; Humans; Indoles; Inhibitory Concentration 50; Isoindoles; Kinetics; Leucovorin; Leukemia; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mutagenesis, Site-Directed; Mutation; Polymorphism, Single-Stranded Conformational; Protein Structure, Secondary; Protein Structure, Tertiary; Quinazolines; Recombinant Proteins; Reduced Folate Carrier Protein; Thymidylate Synthase; Time Factors; Transfection; Trimetrexate; Tumor Cells, Cultured | 2000 |
Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.
Topics: Antibodies; Blotting, Western; Carbachol; Cell Line; Cell Membrane; Chlorides; Colon; Enzyme Inhibitors; ErbB Receptors; Humans; Immunosorbent Techniques; Interferon-gamma; Intestinal Mucosa; Kinetics; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrimidines; Quinazolines; src-Family Kinases; Transforming Growth Factor alpha; Tyrphostins | 2002 |
Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.
Topics: Androstadienes; Butadienes; Cell Line; Chlorides; Epithelial Cells; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Nitriles; Nitrobenzenes; Phospholipases A; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Pyridines; Pyrimidines; Quinazolines; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Sulfonamides; Thrombin; Tyrphostins; Wortmannin | 2002 |
QUINETHAZONE, A NEW ORAL DIURETIC.
Topics: Acetazolamide; Chlorides; Chlorothiazide; Diuretics; Humans; Natriuresis; Pharmacology; Potassium; Quinazolines; Sulfonamides; Urine | 1964 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
Auto-redox reaction: tin(II) chloride-mediated one-step reductive cyclization leading to the synthesis of novel biheterocyclic 5,6-dihydro-quinazolino[4,3-b]quinazolin-8-ones with three-point diversity.
Topics: Chlorides; Cyclization; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Quinazolines; Tin | 2006 |
Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.
Topics: Animals; Calcium; Cell Size; Chloride Channels; Chlorides; Egtazic Acid; Enzyme Inhibitors; ErbB Receptors; Estrenes; Hemostatics; Mice; Osmotic Pressure; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pyrimidines; Pyrrolidinones; Quinazolines; Signal Transduction; src-Family Kinases; Swiss 3T3 Cells; Taurine; Thrombin; Tritium; Tyrphostins | 2008 |
Rutaecarpine induces chloride secretion across rat isolated distal colon.
Topics: Animals; Biological Transport; Chloride Channels; Chlorides; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; In Vitro Techniques; Indole Alkaloids; Potassium Channels; Quinazolines; Rats | 2008 |
2-(Aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines.
Topics: Alkanes; Amination; Chlorides; Indicators and Reagents; Molecular Structure; Oximes; Quinazolines; Zinc Compounds | 2008 |
A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.
Topics: Catalysis; Chlorides; Dimethylformamide; Molecular Structure; Nitriles; Quinazolines; Zinc Compounds | 2009 |
Quercetin stimulates Na+/K+/2Cl- cotransport via PTK-dependent mechanisms in human airway epithelium.
Topics: Brefeldin A; Bumetanide; Cell Line; Chlorides; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Humans; Ion Transport; Protein-Tyrosine Kinases; Quercetin; Quinazolines; Respiratory Mucosa; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Tyrphostins; Valinomycin | 2009 |
JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.
Topics: Amino Acids, Cyclic; Anthracenes; Calcium; Carbachol; Cell Line; Cell Polarity; Chlorides; Cholinergic Agonists; Colon; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Phosphorylation; Potassium; Quinazolines; Thapsigargin; Tyrphostins | 2010 |
Synthesis of 6-trifluoromethylindolo[1,2-c]quinazolines and related heterocycles using N-(2-iodophenyl)trifluoroacetimidoyl chlorides as starting material via C-H bond functionalization.
Topics: Carbon; Chlorides; Heterocyclic Compounds; Hydrogen; Indoles; Molecular Structure; Quinazolines | 2011 |
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling.
Topics: Aminacrine; Bacterial Proteins; Benzamides; Cell Line; Cell Membrane; Chlorides; Ciclopirox; Cold Temperature; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydroxamic Acids; Luminescent Proteins; Mutation; Piperazines; Protein Transport; Pyridones; Quinazolines; Thiazoles; Vorinostat | 2011 |
Synthesis of 3,5-isoxazolidinediones and 1H-2,3-benzoxazine-1,4(3H)-diones from aliphatic oximes and dicarboxylic acid chlorides.
Topics: Benzoxazines; Chlorides; Dicarboxylic Acids; Molecular Structure; Oxazolidinones; Oximes; Quinazolines | 2014 |
Zinc pyrithione inhibits caspase-3 activity, promotes ErbB1-ErbB2 heterodimerization and suppresses ErbB2 downregulation in cardiomyocytes subjected to ischemia/reperfusion.
Topics: Amino Acid Chloromethyl Ketones; Animals; Benzothiazoles; Cardiotonic Agents; Caspase 3; Caspase Inhibitors; Cell Hypoxia; Chlorides; Down-Regulation; ErbB Receptors; Lapatinib; Leupeptins; Myocytes, Cardiac; Organometallic Compounds; Phosphorylation; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Multimerization; Pyridines; Quinazolines; Rats; Receptor, ErbB-2; RNA, Messenger; Thiones; Tyrphostins; Zinc Compounds | 2015 |
Antioxidant activities and molecular docking of 2-thioxobenzo[g]quinazoline derivatives.
Topics: Antioxidants; Binding Sites; Biphenyl Compounds; Chlorides; Ferric Compounds; Free Radicals; Molecular Docking Simulation; Molecular Structure; Oxidation-Reduction; Picrates; Quinazolines | 2019 |
Angular Regioselectivity in the Reactions of 2-Thioxopyrimidin-4-ones and Hydrazonoyl Chlorides: Synthesis of Novel Stereoisomeric Octahydro[1,2,4]triazolo[4,3-
Topics: Chlorides; Pyrimidines; Quinazolines; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2020 |