chlorine and alpha-synuclein

chlorine has been researched along with alpha-synuclein in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, M; Hsu, LJ; Masliah, E; Sisk, A; Sundsmo, M; Takeda, A; Xia, Y1
Lee, JH; Paik, SR; Shin, HJ1
Choi, P; Frasier, M; Golts, N; Snyder, H; Theisler, C; Wolozin, B1
Bower, K; Fink, AL; Li, J; Uversky, VN1
Hardy, J; Hornykiewicz, O; Kattinger, A; Khorchide, M; Pifl, C; Reither, H1
Fink, AL; Henriques, J; Munishkina, LA; Uversky, VN1
Cai, T; Li, Y; Lv, S; Sun, L; Wang, Y; Ye, L; Zhang, Y1
Bauer, J; Berger, ML; Bertl, J; Heinze, G; Hornykiewicz, O; Peneder, TM; Pifl, C; Reither, H; Richfield, EK; Scholze, P1
Ali, AA; Chirwa, S; Gamble-George, J; Goodwin, JS; Khoshbouei, H; North, A; Swant, J1
Anantharam, V; Harischandra, DS; Jin, H; Kanthasamy, A; Kanthasamy, AG1
Deng, Y; Liu, C; Liu, W; Ma, Z; Tan, X; Wang, C; Xu, B; Xu, ZF; Yan, DY; Yang, TY1
Deng, Y; Liu, C; Liu, W; Ma, Z; Tan, X; Wang, C; Xu, B; Xu, ZF; Yan, DY1

Other Studies

12 other study(ies) available for chlorine and alpha-synuclein

ArticleYear
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro.
    Neuroreport, 1999, Mar-17, Volume: 10, Issue:4

    Topics: alpha-Synuclein; Alzheimer Disease; Amyloid; beta-Synuclein; Catalysis; Chlorides; Ferric Compounds; Ferrous Compounds; Humans; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Recombinant Proteins; Synucleins

1999
Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide.
    Archives of biochemistry and biophysics, 2000, Jun-15, Volume: 378, Issue:2

    Topics: Alkylating Agents; alpha-Synuclein; Alzheimer Disease; Catalysis; Chlorides; Copper; Dicyclohexylcarbodiimide; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Ferric Compounds; Humans; Hydrogen Peroxide; Metals; Nerve Tissue Proteins; Oxidation-Reduction; Quinolines; Recombinant Proteins; Spectrometry, Fluorescence; Synucleins; Time Factors

2000
Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: alpha-Synuclein; Amino Acid Substitution; Calcium Chloride; Chlorides; Humans; Iron; Kinetics; Magnesium; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphoproteins; Recombinant Proteins; Spectrophotometry; Synucleins; Zinc Compounds

2002
Synergistic effects of pesticides and metals on the fibrillation of alpha-synuclein: implications for Parkinson's disease.
    Neurotoxicology, 2002, Volume: 23, Issue:4-5

    Topics: alpha-Synuclein; Aluminum Chloride; Aluminum Compounds; Chlorides; Circular Dichroism; Drug Synergism; Humans; Lewy Body Disease; Metals; Nerve Tissue Proteins; Parkinson Disease; Parkinson Disease, Secondary; Pesticides; Protein Conformation; Spectrometry, Fluorescence; Synucleins

2002
alpha-Synuclein selectively increases manganese-induced viability loss in SK-N-MC neuroblastoma cells expressing the human dopamine transporter.
    Neuroscience letters, 2004, Jan-02, Volume: 354, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Cell Death; Cell Line, Tumor; Cell Survival; Chlorides; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ferrous Compounds; Gene Expression; Herbicides; Humans; Manganese Compounds; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neuroblastoma; Synucleins; Transfection

2004
Role of protein-water interactions and electrostatics in alpha-synuclein fibril formation.
    Biochemistry, 2004, Mar-23, Volume: 43, Issue:11

    Topics: Acids; alpha-Synuclein; Anions; Cations, Divalent; Chlorides; Circular Dichroism; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Kinetics; Nerve Tissue Proteins; Polyamines; Polyelectrolytes; Polymers; Protein Structure, Secondary; Recombinant Proteins; Sodium Chloride; Static Electricity; Synucleins; Water

2004
alpha-Synuclein overexpression during manganese-induced apoptosis in SH-SY5Y neuroblastoma cells.
    Brain research bulletin, 2010, Mar-16, Volume: 81, Issue:4-5

    Topics: alpha-Synuclein; Annexin A5; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Chlorides; Humans; Manganese Compounds; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Trace Elements; Transcription, Genetic

2010
Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice.
    Neuroscience, 2011, Apr-28, Volume: 180

    Topics: alpha-Synuclein; Animals; Blotting, Western; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Humans; Immunohistochemistry; Manganese Compounds; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Degeneration; Parkinsonian Disorders; Synaptic Transmission

2011
α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.
    The Journal of biological chemistry, 2011, Dec-23, Volume: 286, Issue:51

    Topics: alpha-Synuclein; Animals; Brain; Chlorides; CHO Cells; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorescent Dyes; Humans; Mice; Neurodegenerative Diseases; Neurons; Patch-Clamp Techniques

2011
α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 143, Issue:2

    Topics: alpha-Synuclein; Animals; Apoptosis; Binding Sites; Blotting, Western; Cell Culture Techniques; Cell Line; Cell Survival; Chlorides; DNA Fragmentation; Dopamine; Dopaminergic Neurons; Humans; Manganese Compounds; Manganese Poisoning; Mesencephalon; Models, Neurological; Parkinson Disease; Protein Binding; Rats; Reactive Oxygen Species; Spectrophotometry, Atomic; Transfection

2015
Effect of the cross-talk between autophagy and endoplasmic reticulum stress on Mn-induced alpha-synuclein oligomerization.
    Environmental toxicology, 2018, Volume: 33, Issue:3

    Topics: Adenine; alpha-Synuclein; Animals; Apoptosis; Autophagy; Brain; Butylamines; Chlorides; Endoplasmic Reticulum Stress; Environmental Pollutants; Manganese; Manganese Compounds; Mice, Inbred C57BL; Neurons; Phenylbutyrates; Polymerization; Signal Transduction; Sirolimus

2018
Mn-Induced Neurocytes Injury and Autophagy Dysfunction in Alpha-Synuclein Wild-Type and Knock-Out Mice: Highlighting the Role of Alpha-Synuclein.
    Neurotoxicity research, 2019, Volume: 36, Issue:1

    Topics: alpha-Synuclein; Animals; Apoptosis; Autophagy; Chlorides; Male; Manganese Compounds; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons

2019