Compounds > chlorine

chlorine and acetylcysteine

chlorine has been researched along with acetylcysteine in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19909 (19.15)18.7374
1990's4 (8.51)18.2507
2000's16 (34.04)29.6817
2010's16 (34.04)24.3611
2020's2 (4.26)2.80

Authors

AuthorsStudies
Bakke, JE; Feil, VJ; Price, CE1
Ryan, AJ1
Clapp, JJ; Kaye, CM; Young, L1
Foulkes, DM; Shaw, BA; Smith, JR1
Carr, AC; Frei, B; Zhu, BZ1
Castegnaro, M; Faucet-Marquis, V; Pfohl-Leszkowicz, A; Pont, F; Rizk, T; Størmer, FC1
Bracher, A; Doran, SF; Leustik, M; Matalon, S; Postlethwait, EM; Squadrito, GL; Yadav, AK1
Bucht, A; Jonasson, S; Koch, B; Wigenstam, E1
Bhullar, IS; Royall, N; Smith, H; Warren, B1
Dong, S; Massalha, N; Nguyen, TH; Plewa, MJ1
Ekstrand-Hammarström, B; Elfsmark, L; Gustafsson, Å; Jonasson, S; Karlsson, T1
Elfsmark, L; Gustafson, Å; Jonasson, S; Karlsson, T1
Bjerrum, OW; Borregaard, N; Jensen, HS1
Drozdz, R; Naskalski, JW; Sznajd, J1
Andersen, JB; Bud, MI; Hjortsø, E; Jensen, NK; Jones, R; Qvist, J; Reid, LM; Thomsen, JL; Wiberg-Jørgensen, F; Zapol, WM1
Bud, JM; Hjortsø, E; Jensen, N; Qvist, J; Thomsen, JL1
Chasseaud, LF1
Eyton-Jones, H; Green, T; Lappin, G; Moore, RB; Pritchard, D; Provan, WM1
Esteban, M; Lee, SB; Mĕlková, Z; Rodriguez, D1
Béani, JC; Cadet, J; Emonet-Piccardi, N; Ravanat, JL; Richard, MJ; Signorini, N1
Oberley, LW; Oberley, TD; Thongphasuk, J1
Delogu, MR; Desole, MS; Enrico, P; Esposito, G; Grella, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, PA1
Fu, J; Zhang, S; Zhou, Z1
Kang, JJ; Kim, EK; Kim, SS; Koh, HJ; Kwon, OW; Lee, JH; Lee, SC; Shin, SH; Song, J1
Cheema, SS; Lopes, EC; Turner, BJ1
Jornot, L; Lacroix, JS; Rochat, T1
Bae, S; Cho, CK; Chung, HY; Hong, SI; Kang, CM; Kang, YH; Kim, MJ; Lee, SJ; Lee, YS; Park, IC; Park, MJ; Park, MT; Rhee, CH; Yi, MJ1
Babar, S; Boudjeltia, KZ; Ducobu, J; Legssyer, I; Moguilevsky, N; Moreau, P; Nève, J; Van Antwerpen, P; Vanhaeverbeek, M1
Temrück, O; Walther, SC; Walther, UI1
Luchese, C; Nogueira, CW; Rocha, JB; Santos, FW; Zeni, G1
Bentzen, PJ; Lang, F1
Cai, T; Chen, J; Chen, Y; Du, K; Li, Y; Luo, W; Yao, T1
Aschner, M; Au, C; Batoréu, MC; Marreilha dos Santos, AP; Milatovic, D; Santos, D1
Barchowsky, A; Leikauf, GD; Nemec, AA; Pitt, BR; Wasserloos, KJ1
Kumar, A; Prakash, A1
Johannesson, M; Oliynyk, I; Roomans, GM; Varelogianni, G1
Chiang, CK; Chien, CT; Hsu, SP; Yang, SY1
Dubé, A; Harrisson, JF; Saint-Gelais, G; Séguin, C1
Aschner, M; Atha, DH; Jain, A; Mazzio, E; Nelson, BC; Renee Reams, R; Schneider, JA; Soliman, KF; Stephenson, AP1
Beitz, DC; Bradner, L; Robbe-Austerman, S; Stabel, JR1
Buccigrossi, V; Guarino, A; Laudiero, G; Miele, E; Monini, M; Ruggeri, FM; Russo, C; Sofia, M1
Jiang, L; Liu, Q; Lu, W; Wang, L; Xu, L; Zhi, Y; Zhong, L; Zhou, P1
Brieger, J; Brochhausen, C; Felder, E; Heim, J; Heinrich, UR; Kaltbeitzel, A; Mailänder, V; Tahir, MN; Tremel, W1
Li, S; Teng, X; Zhu, Y1
Ali, C; Denis, CV; Diamond, SL; Gakuba, C; Gauberti, M; Herbig, BA; Lenting, PJ; Martinez de Lizarrondo, S; Repessé, Y; Touzé, E; Vivien, D1
Chen, J; Ding, X; Li, D; Lu, L; Qiu, Y; Tian, K; Wang, W; Zhao, Q1
Fu, X; Klaunig, JE; Lu, Y; Shi, J; Wang, X; Wu, Q; Zhou, Q; Zhou, S1

Reviews

3 review(s) available for chlorine and acetylcysteine

ArticleYear
The metabolism of pesticidal carbamates.
    CRC critical reviews in toxicology, 1971, Volume: 1, Issue:1

    Topics: Acetylcysteine; Alkylation; Animals; Carbamates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Chromatography, DEAE-Cellulose; Glucuronates; Herbicides; Hydrolysis; Hydroxylation; Pesticides; Rats; Species Specificity; Sulfates

1971
Mechanisms and modification of chlorine-induced lung injury in animals.
    Proceedings of the American Thoracic Society, 2010, Volume: 7, Issue:4

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Chlorine; Gases; Inhalation Exposure; Lung; Lung Diseases; Models, Animal; Rabbits; Rats

2010
ARDS after accidental inhalation of zinc chloride smoke.
    Intensive care medicine, 1988, Volume: 14, Issue:1

    Topics: Acetylcysteine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chlorides; Humans; Lung; Military Personnel; Respiratory Distress Syndrome; Zinc; Zinc Compounds

1988

Trials

1 trial(s) available for chlorine and acetylcysteine

ArticleYear
N-acetylcysteine for the management of anemia and oxidative stress in hemodialysis patients.
    Nephron. Clinical practice, 2010, Volume: 116, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Antioxidants; Case-Control Studies; Chlorides; Dinoprost; Erythropoietin; Female; Ferric Compounds; Hematocrit; Humans; Kidney Failure, Chronic; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Recombinant Proteins; Renal Dialysis

2010

Other Studies

43 other study(ies) available for chlorine and acetylcysteine

ArticleYear
Replacement of a chlorine with a methylsulfonyl group in the metabolism of propachlor (2-chloro-N-isopropylacetanilide).
    Biomedical mass spectrometry, 1976, Volume: 3, Issue:5

    Topics: Acetamides; Acetanilides; Acetylcysteine; Animals; Chlorine; Cysteine; Female; Rats; Sheep; Sulfones

1976
The metabolic formation of mercapturic acids from allyl halides.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:2

    Topics: Acetylcysteine; Alkenes; Allyl Compounds; Animals; Bile; Bromine; Chlorine; Chromatography, Gas; Chromatography, Paper; Cysteine; Glutathione; Iodine; Male; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfoxides; Sulfur Isotopes; Yeasts

1972
Mechanisms of mammalian hydroxylation: some novel metabolites of chlorobenzene.
    Xenobiotica; the fate of foreign compounds in biological systems, 1972, Volume: 2, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Animals; Benzene Derivatives; Carbon Isotopes; Catechols; Chlorine; Chromatography, Gas; Chromatography, Thin Layer; Feces; Female; Hydrocarbons, Halogenated; Hydroquinones; Hydroxylation; Phenols; Rabbits; Spectrophotometry, Ultraviolet

1972
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
    FEBS letters, 2002, Dec-04, Volume: 532, Issue:1-2

    Topics: Acetylcysteine; Aldehydes; alpha 1-Antitrypsin; Antioxidants; Chlorine; Cyclohexanones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ferrocyanides; Glutathione; Hypochlorous Acid; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Oxidative Stress; Pyrrolidines; Serum Albumin; Thiocarbamates

2002
Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA-adduct formation.
    Molecular nutrition & food research, 2006, Volume: 50, Issue:6

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chlorine; Chromatography, High Pressure Liquid; DNA Adducts; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glutathione Synthase; Isoxazoles; Kidney; Mesna; Ochratoxins; Opossums; Oxidative Stress; Spectrometry, Mass, Electrospray Ionization

2006
N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury.
    Toxicology, 2015, Feb-03, Volume: 328

    Topics: Acetylcysteine; Acute Lung Injury; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chlorine; Cytoprotection; Dexamethasone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Fibrinogen; Gases; Inhalation Exposure; Lung; Mice, Inbred BALB C; Neutrophil Infiltration; Plasminogen Activator Inhibitor 1; Time Factors

2015
Novel Treatment of Acute Respiratory Distress Syndrome after Chlorine Gas Inhalation Injury.
    The American surgeon, 2016, Volume: 82, Issue:8

    Topics: Acetylcysteine; Albuterol; Anticoagulants; Bronchodilator Agents; Chemical Warfare Agents; Chlorine; Expectorants; Heparin; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Respiratory Therapy

2016
The impact of disinfection Ct values on cytotoxicity of agricultural wastewaters: Ozonation vs. chlorination.
    Water research, 2018, 11-01, Volume: 144

    Topics: Acetylcysteine; Agriculture; Animals; Chlorine; CHO Cells; Cricetulus; Disinfectants; Disinfection; Halogenation; Ozone; Time Factors; Toxicity Tests, Chronic; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2018
Chlorine exposure induces Caspase-3 independent cell death in human lung epithelial cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 80

    Topics: A549 Cells; Acetylcysteine; Antioxidants; Caspase 3; Cell Physiological Phenomena; Chlorine; Cytokines; Humans; Lung; Oxidants

2022
N-acetyl cysteine mitigates lung damage and inflammation after chlorine exposure in vivo and ex vivo.
    Toxicology and applied pharmacology, 2023, Nov-15, Volume: 479

    Topics: Acetylcysteine; Animals; Antioxidants; Chlorine; Inflammation; Inflammation Mediators; Lung; Lung Injury; Mice; Swine

2023
Prevention of tissue damage: inhibition of myeloperoxidase mediated inactivation of alpha 1-proteinase inhibitor by N-acetyl cysteine, glutathione, and methionine.
    Agents and actions, 1987, Volume: 22, Issue:3-4

    Topics: Acetylcysteine; alpha 1-Antitrypsin; Blood Proteins; Chlorides; Glutathione; Humans; Hydrogen Peroxide; Methionine; Pancreatic Elastase; Peroxidase; Protease Inhibitors

1987
Action of myeloperoxidase-hydrogen peroxide-chloride system on the egg white lysozyme.
    Acta biochimica Polonica, 1988, Volume: 35, Issue:4

    Topics: Acetylcysteine; Chlorides; Cystine; Egg White; Electrophoresis, Polyacrylamide Gel; Enzyme Repression; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Methionine; Muramidase; Peroxidase; Tryptophan

1988
[Zinc chloride poisoning--observations and treatment].
    Nordisk medicin, 1988, Volume: 103, Issue:2

    Topics: Acetylcysteine; Adult; Chlorides; Humans; Male; Military Personnel; Proline; Zinc; Zinc Compounds

1988
Reaction with electrophiles after enzyme-catalysed deacetylation of N-acetylcysteine.
    Biochemical pharmacology, 1974, Mar-15, Volume: 23, Issue:6

    Topics: Acetone; Acetylcysteine; Amidohydrolases; Animals; Benzyl Compounds; Carnivora; Chlorides; Chromatography, Paper; Columbidae; Cytosol; Dialysis; Dogs; Ethers; Female; Fumarates; Glutathione; Glycolates; Guinea Pigs; Iodides; Liver; Male; Maleates; Mice; Rabbits; Rats; Species Specificity; Sulfones; Vinyl Compounds

1974
The incorporation of radiolabelled sulphur from captan into protein and its impact on a DNA binding study.
    Chemico-biological interactions, 1995, May-19, Volume: 96, Issue:2

    Topics: Acetylcysteine; Animals; Bone Marrow; Captan; Cesium; Chlorides; Chromatography, High Pressure Liquid; DNA; DNA-Binding Proteins; Duodenum; Gastric Mucosa; Isotope Labeling; Jejunum; Liver; Male; Mice; Proteins; Sulfur Radioisotopes; Ultracentrifugation

1995
Bcl-2 prevents nitric oxide-mediated apoptosis and poly(ADP-ribose) polymerase cleavage.
    FEBS letters, 1997, Feb-24, Volume: 403, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Caspase 1; Chlorides; Cysteine Endopeptidases; DNA; Gene Expression; Genes, bcl-2; Genetic Vectors; Glutathione; HeLa Cells; Humans; Isopropyl Thiogalactoside; Lipid Peroxidation; Mice; Nitric Oxide; Nitric Oxide Synthase; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Thiobarbituric Acid Reactive Substances; Vaccinia virus; Zinc Compounds

1997
Protective effects of antioxidants against UVA-induced DNA damage in human skin fibroblasts in culture.
    Free radical research, 1998, Volume: 29, Issue:4

    Topics: Acetylcysteine; Adult; Antioxidants; Breast; Cells, Cultured; Chlorides; DNA Damage; Electrophoresis, Agar Gel; Female; Fibroblasts; Humans; Skin; Sodium Selenite; Ultraviolet Rays; Zinc Compounds

1998
Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells.
    Archives of biochemistry and biophysics, 1999, May-15, Volume: 365, Issue:2

    Topics: Acetylcysteine; Breast Neoplasms; Cell Survival; Chlorides; Citrate (si)-Synthase; Cyclic N-Oxides; Cycloheximide; Enzyme Induction; Female; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Manganese Compounds; Manganese Poisoning; RNA, Messenger; Superoxide Dismutase; Transcription, Genetic; Tumor Cells, Cultured

1999
Manganese increases L-DOPA auto-oxidation in the striatum of the freely moving rat: potential implications to L-DOPA long-term therapy of Parkinson's disease.
    British journal of pharmacology, 2000, Volume: 130, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Chlorides; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis Solutions; Dopamine; Homovanillic Acid; Infusion Pumps; Levodopa; Male; Manganese; Manganese Compounds; Microdialysis; Movement; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Wistar; Time Factors; Uric Acid

2000
In vitro effect of manganese chloride exposure on reactive oxygen species generation and respiratory chain complexes activities of mitochondria isolated from rat brain.
    Toxicology in vitro : an international journal published in association with BIBRA, 2004, Volume: 18, Issue:1

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Brain; Chlorides; Cytochromes c; Dose-Response Relationship, Drug; Drug Combinations; Electron Transport; Glutathione; Manganese Compounds; Membrane Potentials; Mitochondria; NADH, NADPH Oxidoreductases; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodamine 123; Succinate Dehydrogenase; Ubiquinone

2004
Zn2+-induced cell death is mediated by the induction of intracellular ROS in ARPE-19 cells.
    Current eye research, 2004, Volume: 28, Issue:3

    Topics: Acetylcysteine; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Chlorides; Fluorescein-5-isothiocyanate; Humans; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Necrosis; p38 Mitogen-Activated Protein Kinases; Pigment Epithelium of Eye; Reactive Oxygen Species; Zinc Compounds

2004
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
    Journal of cellular biochemistry, 2004, Apr-01, Volume: 91, Issue:5

    Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Chelating Agents; Chlorides; Copper; Detergents; Disease Models, Animal; Ditiocarb; Fibroblasts; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Minocycline; Mutation; Oxidative Stress; Paraquat; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds

2004
N-acetylcysteine inhibits Na+ absorption across human nasal epithelial cells.
    Journal of cellular physiology, 2004, Volume: 201, Issue:1

    Topics: Acetylcysteine; Amiloride; Cell Polarity; Cells, Cultured; Chlorides; Cystic Fibrosis; Diffusion Chambers, Culture; Diuretics; Epithelial Sodium Channels; Expectorants; Glutathione; Humans; Membrane Potentials; Nasal Mucosa; Potassium; RNA, Messenger; Sodium; Sodium Channels; Sodium-Potassium-Exchanging ATPase

2004
Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria.
    Cancer research, 2004, Dec-15, Volume: 64, Issue:24

    Topics: Acetylcysteine; Apoptosis; Apoptosis Inducing Factor; Arsenicals; Caspases; Cell Line, Tumor; Cell Nucleus; Chlorides; Enzyme Activation; Female; Flavoproteins; Humans; Intracellular Membranes; Membrane Potentials; Membrane Proteins; Mitochondria; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Uterine Cervical Neoplasms

2004
Thiol-containing molecules interact with the myeloperoxidase/H2O2/chloride system to inhibit LDL oxidation.
    Biochemical and biophysical research communications, 2005, Nov-11, Volume: 337, Issue:1

    Topics: Acetylcysteine; Antioxidants; Captopril; Chlorides; Flufenamic Acid; Glutathione; Hydrogen Peroxide; Lipoproteins, LDL; Lysine; Oxidation-Reduction; Peroxidase; Sulfhydryl Compounds

2005
Effect of enlarged glutathione on zinc-mediated toxicity in lung-derived cell lines.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:3

    Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Survival; Chlorides; Dose-Response Relationship, Drug; Drug Combinations; Epithelial Cells; Free Radical Scavengers; Glutathione; Humans; Hydrocortisone; Isomerism; Pulmonary Alveoli; Rats; Zinc Compounds

2007
Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.
    Chemico-biological interactions, 2007, Jan-30, Volume: 165, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Cadmium Chloride; Chelating Agents; Chlorides; Dithiothreitol; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Environmental Pollutants; Enzyme Inhibitors; Lung; Male; Organoselenium Compounds; Porphobilinogen Synthase; Rats; Rats, Wistar; Succimer; Unithiol; Zinc Compounds

2007
Effect of anandamide on erythrocyte survival.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:6

    Topics: Acetylcysteine; Annexin A5; Arachidonic Acids; Calcium; Cell Survival; Chlorides; Cyclooxygenase Inhibitors; Cytosol; Endocannabinoids; Erythrocytes; Flow Cytometry; Humans; Osmotic Pressure; Phosphatidylserines; Polyunsaturated Alkamides

2007
Proteasome inhibition is associated with manganese-induced oxidative injury in PC12 cells.
    Brain research, 2007, Dec-14, Volume: 1185

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Apoptosis; Cell Count; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Manganese Compounds; Oxidative Stress; PC12 Cells; Proteasome Endopeptidase Complex; Protein Carbonylation; Rats; Tetrazolium Salts; Thiazoles; Trace Elements

2007
Antioxidants prevent the cytotoxicity of manganese in RBE4 cells.
    Brain research, 2008, Oct-21, Volume: 1236

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Cell Line, Transformed; Cell Survival; Chlorides; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Glutathione; L-Lactate Dehydrogenase; Manganese Compounds; Rats; Sulfates; Tetrazolium Salts; Thiazoles

2008
Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2009, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Bronchi; Cell Separation; Cells, Cultured; Chelating Agents; Chlorides; DNA-Binding Proteins; Epithelial Cells; Ethylamines; Flow Cytometry; Fluorescent Dyes; Humans; Metallothionein; Mice; Mice, Knockout; Nickel; Polycyclic Compounds; Pyridines; Pyrimidines; Reactive Oxygen Species; RNA, Messenger; Time Factors; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Zinc Compounds

2009
Effect of N-acetyl cysteine against aluminium-induced cognitive dysfunction and oxidative damage in rats.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:2

    Topics: Acetylcholinesterase; Acetylcysteine; Aluminum Chloride; Aluminum Compounds; Animals; Brain; Catalase; Chlorides; Cognition Disorders; Glutathione; Lipid Peroxidation; Male; Maze Learning; Memory; Motor Activity; Oxidative Stress; Rats; Rats, Wistar

2009
The effect of N-acetylcysteine on chloride efflux from airway epithelial cells.
    Cell biology international, 2010, Jan-27, Volume: 34, Issue:3

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chlorides; Cystic Fibrosis; Epithelial Cells; Humans; Immunohistochemistry; Oxidative Stress; Respiratory Mucosa

2010
Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1).
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2011, Volume: 89, Issue:6

    Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Hypoxia; Chlorides; Chromosome Mapping; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genes, Reporter; HEK293 Cells; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Luciferases; Metallothionein; Methacrylates; Mice; Mutagenesis, Site-Directed; NIH 3T3 Cells; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Stability; Rotenone; Signal Transduction; Thiazoles; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection; Zinc Compounds

2011
Manganese-induced oxidative DNA damage in neuronal SH-SY5Y cells: attenuation of thymine base lesions by glutathione and N-acetylcysteine.
    Toxicology letters, 2013, Apr-26, Volume: 218, Issue:3

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Chlorides; Comet Assay; DNA Breaks, Single-Stranded; Dose-Response Relationship, Drug; Flow Cytometry; Gas Chromatography-Mass Spectrometry; Glutathione; Humans; In Situ Nick-End Labeling; Manganese Compounds; Manganese Poisoning; Neurons; Neuroprotective Agents; Oxidative Stress; Thymine

2013
Short communication: Application of an N-acetyl-L-cysteine-NaOH decontamination method for the recovery of viable Mycobacterium avium subspecies paratuberculosis from milk of naturally infected cows.
    Journal of dairy science, 2014, Volume: 97, Issue:6

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Cetylpyridinium; Chlorides; Decontamination; Female; Milk; Mycobacterium avium subsp. paratuberculosis; Paratuberculosis; Polymerase Chain Reaction; Sodium Hydroxide

2014
Chloride secretion induced by rotavirus is oxidative stress-dependent and inhibited by Saccharomyces boulardii in human enterocytes.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Acetylcysteine; Antioxidants; Caco-2 Cells; Cell Line, Tumor; Chlorides; Enterocytes; Glutathione; Glycoproteins; Humans; Intestinal Mucosa; Intestines; Oxidative Stress; Reactive Oxygen Species; Rotavirus; Rotavirus Infections; Saccharomyces; Toxins, Biological; Viral Nonstructural Proteins

2014
The role of nitric oxide synthase signaling pathway in the Zn-induced cellular responses in MCF-7 cells.
    Environmental toxicology and pharmacology, 2014, Volume: 38, Issue:3

    Topics: Acetylcysteine; Apoptosis; Arginine; Calcium; Cell Proliferation; Chlorides; Female; Humans; MCF-7 Cells; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Transcription Factors; Zinc Compounds

2014
Genotoxic effects of zinc oxide nanoparticles.
    Nanoscale, 2015, May-21, Volume: 7, Issue:19

    Topics: Acetylcysteine; Cell Line, Tumor; Cell Survival; Chlorides; DNA Breaks, Double-Stranded; Humans; Metal Nanoparticles; Microscopy, Electron, Transmission; Reactive Oxygen Species; Zinc Compounds; Zinc Oxide

2015
The involvement of the mitochondrial pathway in manganese-induced apoptosis of chicken splenic lymphocytes.
    Chemosphere, 2016, Volume: 153

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Calmodulin; Caspase 3; Cells, Cultured; Chickens; Chlorides; Glutathione Peroxidase; Lymphocytes; Malondialdehyde; Manganese Compounds; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Spleen; Superoxide Dismutase; Tumor Suppressor Protein p53

2016
Potent Thrombolytic Effect of
    Circulation, 2017, Aug-15, Volume: 136, Issue:7

    Topics: Acetylcysteine; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Mice; Platelet Aggregation; Ristocetin; Thromboembolism; Thrombosis; Tissue Plasminogen Activator; von Willebrand Factor

2017
N-Acetylcysteine protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels.
    Toxicology letters, 2017, Sep-05, Volume: 279

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Apoptosis; Caspase 3; Chlorides; Cytoprotection; Dose-Response Relationship, Drug; Hair Cells, Auditory, Inner; Manganese Compounds; Neuroprotective Agents; Organ Culture Techniques; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Spiral Ganglion; Time Factors

2017
Autophagy plays a protective role in Mn-induced toxicity in PC12 cells.
    Toxicology, 2018, 02-01, Volume: 394

    Topics: Acetylcysteine; Animals; Autophagy; Cell Respiration; Chlorides; Chloroquine; Dopamine; Manganese Compounds; Mitochondria; Neurosecretory Systems; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes

2018