chlorethylclonidine has been researched along with clonidine in 279 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (2.15) | 18.7374 |
| 1990's | 216 (77.42) | 18.2507 |
| 2000's | 51 (18.28) | 29.6817 |
| 2010's | 6 (2.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mallard, NJ; Marshall, RW; Sithers, AJ; Spriggs, TL | 1 |
| Etgen, AM; Karkanias, GB; Petitti, N | 1 |
| Aniukhovskiĭ, EP; Rozen, MP; Staĭnberg, SF | 1 |
| Chen, YM; Han, QD | 1 |
| Elhawary, AM; Pettinger, WA; Wolff, DW | 1 |
| Kowatch, MA; Miyamoto, A; Roth, GS; Villalobos-Molina, R | 1 |
| Esbenshade, TA; Han, C; Minneman, KP | 1 |
| Piascik, MT; Pruitt, TA; Sparks, MS | 2 |
| Chiba, S; Skrbic, R | 1 |
| Blue, DR; Clarke, DE; Vimont, RL | 1 |
| Bevan, JA; Bevan, RD; Oriowo, MA | 1 |
| Hayakawa, H; Shimizu, M; Yamawaki, S | 1 |
| Boer, R; Eltze, M | 1 |
| Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| García-Sáinz, JA; Macías-Silva, M; Olivares-Reyes, JA; Romero-Avila, T | 1 |
| Kojima, C; Satoh, M; Takayanagi, I | 1 |
| Feller, DR; Hamada, A; Miller, DD; Patil, PN; Shams, G; Venkataraman, BV | 1 |
| Harada, M; Koike, K; Satoh, M; Takayanagi, I | 1 |
| Anyukhovsky, EP; Rosen, MR | 1 |
| Muramatsu, I | 1 |
| Breschi, MC; Ciucci, MA; Martinotti, E; Nieri, P; Omini, C; Pani, M | 1 |
| Abel, PW; Feng, F; Jeffries, WB; Pettinger, WA | 1 |
| García-Sáinz, JA; Torres-Márquez, ME; Villalobos-Molina, R | 1 |
| Anyukhovsky, EP; Molina-Viamonte, V; Rosen, MR | 1 |
| Piascik, MT; Pruitt, TA; Soltis, EE; Sparks, MS | 1 |
| Han, CD; Minneman, KP | 1 |
| Gross, G; Ravens, U; Wang, XL; Wettwer, E | 1 |
| Endoh, M; Norota, I; Takanashi, M | 1 |
| Schwietert, HR; van Zwieten, PA; Wilffert, B; Wilhelm, D | 1 |
| Mante, S; Minneman, KP | 1 |
| Moriya, M; Takayanagi, I | 1 |
| Kigoshi, S; Muramatsu, I; Ohmura, T | 1 |
| Kigoshi, S; Muramatsu, I; Oshita, M | 3 |
| Bell, K; Insel, PA; Klijn, K; Slivka, SR | 1 |
| Han, C; Li, J; Minneman, KP | 1 |
| Hashimoto, S; Kigoshi, S; Muramatsu, I; Ohmura, T; Oshita, M | 1 |
| Gross, G; Hanft, G; Michel, MC | 3 |
| Deth, RC; Gupta, S; Tian, WN | 1 |
| Butler, BT; Kusiak, JW; Piascik, MT; Pruitt, TA | 1 |
| Endo, T; Onaya, T; Shimura, H | 1 |
| Terman, BI | 1 |
| Hashimoto, K; Suzuki, E; Tamura, K; Tsujimoto, G | 1 |
| Casebolt, TL; Jope, RS; Li, XH | 1 |
| Hashimoto, K; Suzuki, E; Tsujimoto, G | 1 |
| Endo, T; Hashimoto, K; Onaya, T; Shimura, H; Tsujimoto, G; Watanabe, K | 1 |
| Han, CD; Minneman, KP; Wilson, KM | 1 |
| Butler, BT; Piascik, MT; Pruitt, TA | 1 |
| Minneman, KP; Wilson, KM | 3 |
| del Balzo, U; Kaplan, LM; Malfatto, G; Rosen, MR; Steinberg, SF | 1 |
| Bevan, JA; Oriowo, MA | 1 |
| Johnson, RD; Minneman, KP | 1 |
| Hashimoto, K; Suzuki, E; Tsujimoto, A; Tsujimoto, G | 1 |
| Bowersox, S; Ciaranello, R; Dement, WC; Frusthofer, B; Guilleminault, C; Maddaluno, J; Mignot, E; Nishino, S | 1 |
| Abel, PW; Han, C; Minneman, KP | 2 |
| Kow, LM; Pfaff, DW | 1 |
| Brodde, OE; Büscher, R; Erdbrügger, W; Kerker, J; Kraneis, H; Michel, MC | 1 |
| Johns, EJ; Sattar, MA | 2 |
| Abdul Sattar, M; Johns, EJ | 1 |
| Han, C; Yu, GS | 1 |
| Iwanov, V; Jiang, GC; Moulds, RF | 2 |
| Burt, RP; Chapple, CR; Marshall, I | 1 |
| Hamada, K; Inagaki, O; Kawabe, K; Kurimoto, S; Moriyama, N; Takanashi, M | 1 |
| Kokubu, N; Matsuo, K; Satoh, M; Takayanagi, I | 1 |
| Amobi, NI; Smith, IC | 1 |
| Chueh, SC; Guh, JH; Ko, FN; Teng, CM | 1 |
| Foglar, R; Horie, K; Obika, K; Ogawa, S; Sakamoto, A; Shibata, K; Tsujimoto, G | 1 |
| Graham, D; Langer, SZ; Pimoule, C | 1 |
| Badia, A; Gascón, S; Ivorra, D; Vila, E | 1 |
| García-Sáinz, JA; González-Espinosa, C; Romero-Avila, MT | 1 |
| Adachi, M; Manita, S; Matsuda, T; Shigenobu, K; Tanaka, H | 1 |
| Kennedy, RH; Lindemann, JP; Seifen, E; Williamson, AP | 4 |
| Cai, G; Gurdal, H; Johnson, MD | 1 |
| Guarneri, L; Leonardi, A; Poggesi, E; Simonazzi, I; Taddei, C; Testa, R | 1 |
| Horie, K; Tsujimoto, G | 1 |
| Kigoshi, S; Muramatsu, I; Muraoka, R; Noguchi, H | 2 |
| Hirasawa, A; Horie, K; Tsujimoto, G | 1 |
| Hatano, A; Koizumi, T; Komeyama, T; Takahashi, H; Takeda, M; Tamaki, M | 1 |
| Aston, N; Chess-Williams, R; Couldwell, C | 1 |
| Guh, JH; Ko, FN; Teng, CM | 1 |
| Gould, DJ; Hill, CE | 1 |
| Bowdish, DM; Gaspar, V; Low, AM; Prashad, TR | 1 |
| Guimarães, S; Nunes, JP | 1 |
| Kokubu, N; Satoh, M; Takayanagi, I | 1 |
| Edwards, FR; Hill, CE; Hirst, GD; Klemm, M | 1 |
| Guarneri, L; Ibba, M; Leonardi, A; Poggesi, E; Simonazzi, I; Strada, G; Taddei, C; Testa, R | 1 |
| Badia, A; Dierssen, M; Gascón, S; Màrmol, F; Vivas, NM | 1 |
| Chess-Williams, R; Couldwell, C; Jackson, A; O'Brien, H | 1 |
| Chen, C; Gopalakrishnan, SM; Lokhandwala, MF | 1 |
| Duarte, J; Jiménez, J; Pérez-Vizcaíno, F; Tamargo, J; Zarzuelo, A | 1 |
| Fleming, WW; Kong, JQ; Taylor, DA | 1 |
| Büscher, R; Insel, PA; Michel, MC | 1 |
| Aniukhovskiĭ, EP; Rosen, MR | 1 |
| Anyukhovsky, EP; Cohen, IS; Rosen, MR; Steinberg, SF | 1 |
| Badia, A; Sallés, J | 1 |
| Casas-González, P; García-Sáinz, JA; González-Espinosa, C; Romero-Avila, MT | 1 |
| Chen, MZ; Han, QD; Yu, GS | 1 |
| Daniel, EE; Hoo, KH; Kwan, CY | 1 |
| Cable, DG; Dreyer, ER; Martins, JB; Rath, TE | 1 |
| Perez, DM; Piascik, MT; Smith, MS; Soltis, EE | 1 |
| Cohen, MV; Downey, JM; Liu, GS; Liu, Y; Tsuchida, A | 1 |
| Oriowo, MA | 1 |
| Glowinski, J; Marin, P; Premont, J; Tassin, JP; Trovero, F | 1 |
| Bard, JA; Branchek, TA; Forray, C; Laz, TM; Smith, KE; Vaysse, PJ; Weinshank, RL | 1 |
| Anversa, P; Capasso, JM; Cheng, W; Coupet, J; Hamby, CV; Li, P; Meggs, LG; Reiss, K | 1 |
| Asano, M; Honda, K; Inagaki, O; Kawabe, K; Kimura, R; Mori, R; Suzuki, M; Takenaka, T; Tanaka, C; Yamada, S | 1 |
| Nagashima, M | 1 |
| Gorman, AJ; Vargas, HM; Zhou, L | 1 |
| Daley, J; Goldstein, I; Netsuwan, N; Padman-Nathan, H; Saenz de Tejada, I; Traish, AM | 1 |
| Ambler, SK; Leite, MF | 1 |
| Lepor, H; Meretyk, S; Shapiro, E; Tang, R | 1 |
| Bültmann, R; Starke, K | 1 |
| Fahrig, T | 1 |
| Kennedy, RH; Lindemann, JP; Seifen, E; Stimers, JR; Williamson, AP | 1 |
| Lepor, H; Shapiro, E; Tang, R | 1 |
| Lee, JH; Rosen, MR | 1 |
| Cunningham, D; Gorman, AJ; Hartman, HB; Vargas, HM; Zhou, L | 1 |
| Hagino, Y; Hasegawa, S; Kondo, H; Nomura, H; Nomura, T; Sumi-Ichinose, C; Tachibana, M; Ukai, K; Watanabe, T; Yokoyama, R | 1 |
| Maruyama, K; Nagatomo, T; Ohkura, N; Yagi, Y | 1 |
| Honda, K; Yazawa, H | 1 |
| Mironneau, C; Mironneau, J; Neuilly, G; Rakotoarisoa, L; Sayet, I | 1 |
| Hatano, A; Koizumi, T; Komeyama, T; Takahashi, H; Takeda, M; Tamaki, M; Tsutsui, T | 1 |
| Colucci, WS; Izzo, NJ | 1 |
| Bard, JA; Branchek, TA; Chiu, G; Forray, C; Hartig, PR; Lepor, H; Shapiro, E; Tang, R; Weinshank, RL; Wetzel, JM | 1 |
| Hua, Z; Wang, XL | 1 |
| Barron, KW; Piascik, MT; Smith, MS; Soltis, EE | 1 |
| Branchek, TA; Forray, C; Kerker, J; Michel, MC | 1 |
| Ballejo, G; Queiroz-Neto, A | 1 |
| Shima, S | 1 |
| Esbenshade, TA; Han, C; Minneman, KP; Murphy, TJ | 1 |
| García-Sáinz, JA; Romero-Avila, MT | 1 |
| Chen, L; Eckhart, AD; Faber, JE; Xin, X; Yang, N | 1 |
| Canessa, LM; Felder, RA; Jose, PA; Piccio, MM; Porter, CC; Robillard, JE; Sidhu, A; Vachvanichsanong, P | 1 |
| Docherty, JR; Kearns, S; O'Rourke, M | 1 |
| Chapple, CR; Chess-Williams, R; Furukawa, K; Rosario, DJ; Smith, DJ; Uchiyama, T | 1 |
| Büscher, R; Heeks, C; Michel, MC; Taguchi, K | 1 |
| Akrong, J; Boyd, J; Chen, CK; Daniel, EE; Duerksen, S; Gaspar, V; Green, J; Kwan, CY; Low, AM; Lu-Chao, H; Soyka, C | 1 |
| Dong, ED; Han, QD | 1 |
| Cua, M; Danilo, P; Geller, JC; Guo, SD; Prieto, L; Rosen, MR | 1 |
| Anwar, N; Klein, DC; Sugden, D | 1 |
| Dyer, DC; Nair, R | 1 |
| Eltze, M | 1 |
| Endoh, M; Yang, HT | 1 |
| Akaishi, Y; Hattori, Y; Kanno, M; Nagashima, M | 1 |
| Akaishi, Y; Hattori, Y; Kanno, M; Kitabatake, A; Nagashima, M; Sakuma, I; Tohse, N | 1 |
| Benoit, JN; Gao, H; Korthuis, RJ | 1 |
| Choe, EU; Ferrara, JJ; Flint, LM; Hoang, TV; Hyman, AL; Lippton, HL | 1 |
| Arias-Montaño, JA; De la Vega, MT; Trejo, F | 1 |
| Docherty, JR; O'Rourke, M | 1 |
| Aceves, J; Arias-Montaño, JA; Nuñez, A | 1 |
| Koike, K; Okayasu, A; Satoh, M; Takayanagi, I | 1 |
| Homuth, V; Luther, HP; Wallukat, G | 1 |
| Fujimoto, S; Sumi-Fujimoto, K | 1 |
| Moulds, RF; Tognarini, DP | 1 |
| Ibarra, M; López-Guerrero, JJ; Terrón, JA; Villalobos-Molina, R | 1 |
| Ibarra, M; López-Guerrero, JJ; Villalobos-Molina, R | 3 |
| Dougall, IG; Fagura, MS; Lydford, SJ | 1 |
| Osnes, JB; Sandnes, D; Skomedal, T; Viko, H | 1 |
| Dyer, DC; Hu, XQ | 1 |
| Hattori, Y; Kanno, M; Nagashima, M; Tohse, N | 1 |
| Jurkiewicz, A; Jurkiewicz, NH; Pupo, AS | 1 |
| Cheng, JT; Tong, YC | 1 |
| Han, C; Zhang, Y; Zhu, W | 1 |
| Hattori, Y; Kanno, M | 1 |
| Andersen, GO; Enger, M; Osnes, JB; Skomedal, T | 1 |
| Guimarães, S; Paiva, MQ; Pereira, O | 1 |
| Arai, M; Fujiwara, H; Fujiwara, T; Kariya, T; Koshiji, M; Minatoguchi, S; Ohno, T; Uno, Y; Yamashita, K | 1 |
| Awaji, T; Hirasawa, A; Ito, H; Sugawara, T; Tsujimoto, G; Tsumaya, K | 1 |
| Benoit de Coignac, A; Coudouel, N; Legrand, C; Limon-Boulez, I; Maltier, JP; Mhaouty-Kodja, S | 1 |
| Forster, C; Le Tran, Y | 1 |
| Docherty, JR; Gavin, K; O'Rourke, M | 1 |
| Macmillan, JB; McGrath, JC; Smith, KM | 1 |
| Daniel, EE; Gaspar, V; Kwan, CY; Low, AM; Lu-Chao, H | 1 |
| Asakura, Y; Ebihara, Y; Hasegawa, H; Nakamura, Y; Shinmura, K; Suganuma, Y; Tani, M | 1 |
| García-Sáinz, JA; Vázquez-Prado, J; Villalobos-Molina, R | 1 |
| Hirano, K; Kanaide, H; Nishimura, J; Seguchi, H; Zhou, Y | 1 |
| Cockcroft, V; Heinonen, P; Marjamaki, A; Pihlavisto, M; Savola, JM; Scheinin, M | 1 |
| Chevalier, P; Danilo, P; Rosen, MR; Ruffy, F | 1 |
| Hasegawa, Y; Ono, H; Wada, T | 1 |
| Han, C; Lu, Z; Wei, H; Xu, K; Zhang, Y | 1 |
| Capogrossi, MC; Gambassi, G; Lakatta, EG; Spurgeon, HA; Ziman, BD | 1 |
| Brown, RD; Daniel, EE; Kwan, CY; Low, AM; Lu-Chao, H; Wang, YF | 1 |
| Mita, M; Walsh, MP | 1 |
| Awaji, T; Hirasawa, A; Sugawara, T; Tsujimoto, G | 1 |
| Avkiran, M; Yasutake, M; Yokoyama, H | 1 |
| Jeffries, WB; Scofield, MA; Xiao, L | 1 |
| Jeffries, WB; Xiao, L | 1 |
| Pupo, AS | 1 |
| Hattori, K; Makara, Y; Maruyama, K; Nagatomo, T; Ohnuki, T; Suzuki, M; Tsuchiya, M; Watanabe, K | 1 |
| Cotecchia, S; Michel, MC; Reese, J; Yang, M | 1 |
| Campos-Mello, C; Correa, FM; de Oliveira, AM; Leitão, MC | 1 |
| Demenge, P; Godin-Ribuot, D; Joyeux, M; Patel, A; Ribuot, C; Yellon, DM | 1 |
| García-Sáinz, JA; Torres-Padilla, ME | 1 |
| Alvarez-Guerra, M; Bertholom, N; Garay, RP | 1 |
| Li, W; Wang, XL; Zhang, Y | 1 |
| Errasti, AE; Rothlin, RP; Sardi, SP; Torres, RM; Velo, MP | 1 |
| Amobi, N; Coker, C; Guillebaud, J; Mulvin, D; Smith, IC | 1 |
| Kocić, I | 1 |
| Saxena, PR; Stam, WB; Van der Graaf, PH | 1 |
| Goda, N; Nakayama, Y; Ohmi, K; Shinoura, H; Tsujimoto, G | 1 |
| Amobi, NI; Smith, IC; Sugden, D | 1 |
| Frang, H; Hoffrén, AM; Javitch, JA; Johnson, MS; Kallio, J; Marjamäki, A; Pihlavisto, M; Salminen, T; Scheinin, M | 1 |
| Barrett-Jolley, R; Dart, C; Standen, NB | 1 |
| Avellar, MC; Megale, A; Porto, CS; Silva, MA | 1 |
| Boselli, C; Grana, E | 1 |
| Arias-Montaño, JA; Berger, VA; Soria-Jasso, LE; Young, JM | 1 |
| Antzelevitch, C; Burashnikov, A | 1 |
| Sasa, M; Tanimitsu, N; Tsuru, H; Yajin, K | 1 |
| Arendshorst, WJ; Brännström, K; Salomonsson, M | 1 |
| Delgado, C; Martínez, ML | 1 |
| Ibarra, M; Lopez-Guerrero, JJ; Pardo, JP; Villalobos-Molina, R | 1 |
| Parker, MS; Parker, SL | 1 |
| Gordon, S; Koman, LA; Li, Z; Rosencrance, E; Silver, WP; Smith, TL; Strandhoy, JW | 1 |
| Hashimito, K; Hirasawa, A; Homma, N; Shibata, K; Tsujimoto, G | 1 |
| de Groat, WC; Somogyi, GT; Széll, EA; Yamamoto, T | 1 |
| Chen, PC; Cheng, JT; Liu, IM; Yen, ST | 1 |
| Becker, K; Brodde, OE; Dhein, S; Giessler, C; Pönicke, K | 1 |
| Inagaki, C; Oshiro, A; Otani, H; Yagi, M | 1 |
| Coats, P; Hillier, C; Jarajapu, YP; MacDonald, A; McGrath, JC | 1 |
| Hillier, C; Jarajapu, YP; MacDonald, A | 1 |
| Koike, K; Yamamoto, Y | 1 |
| Chiba, S; Taguchi, Y; Yang, XP | 1 |
| D'Ocon, P; Gisbert, R; Ivorra, MD; Noguera, MA; Ziani, K | 1 |
| Brodde, OE; Dhein, S; Giessler, C; Heinroth-Hoffmann, I; Leineweber, K; Seyfarth, T | 1 |
| Han, Q; Peng, M; Xue, Z; Zhang, Y | 1 |
| Chiba, S; Tsukada, M | 1 |
| Hashimoto, K; Hirasawa, A; Sugawara, T; Tsujimoto, G | 1 |
| Katus, HA; Kemken, D; Kurz, T; Mier, K; Richardt, G | 1 |
| Brodde, OE; Dhein, S; Giessler, C; Silber, RE; Wangemann, T | 1 |
| Castrejón-Sosa, M; Guinzberg, R; Piña, E; Villalobos-Molina, R | 1 |
| Arévalo-León, LE; Gallardo-Ortíz, IA; Urquiza-Marín, H; Villalobos-Molina, R | 1 |
| Chiba, S; Yang, XP | 1 |
| Campos, M; Morais, Pde L; Pupo, AS | 2 |
| Hillier, C; MacDonald, A; Zacharia, J | 2 |
| Eltze, M; Jähnichen, S; Pertz, HH | 1 |
| Abdullah, NA; Armenia, A; Helmi, A; Johns, EJ; Munavvar, AS | 1 |
| Avellar, MC; Hamamura, M; Mendes, FR; Porto, CS; Queiróz, DB | 1 |
| Badura, LL; Dodge, JC | 1 |
| Abel, PW; Bockman, CS; Bruchas, MR; Dowd, FJ; O'Connell, KA; Scofield, MA; Zeng, W | 1 |
| Baber, SR; Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD | 1 |
| Ding, X; McCune, DF; Murray, PA; Perez, DM; Sohn, JT | 1 |
| Daly, CJ; Hillier, C; MacDonald, A; McGrath, JC; Tanoue, A; Tsujimoto, G; Zacharia, J | 1 |
| Farias-Rodríguez, VM; Gallardo-Ortíz, IA; Gómez-Zamudio, JH; Lázaro-Suárez, ML; Tanoue, A; Tsujimoto, G; Villalobos-Molina, R | 1 |
| Angeli, P; Buccioni, M; Giardinà, D; Gulini, U; Marucci, G; Melchiorre, C; Sagratini, G; Testa, R | 1 |
| Avellar, MC; Caricati-Neto, A; Jurkiewicz, A; Jurkiewicz, NH; Reuter, HR; Verde, LF | 1 |
| Chartier, D; Ehrlich, JR; Hébert, TE; Nattel, S; Qi, X; Yeh, YH | 1 |
| Chen, L; Gao, H; Yang, HT | 1 |
| Abdullah, NA; Johns, EJ; Khan, AH; Sattar, MA | 1 |
| Campos-Peralta, JM; Gallardo-Ortíz, IA; Ibarra, M; Martínez-Salas, SG; Pares-Hipolito, J; Villalobos-Molina, R | 1 |
| Inada, Y; Kobayashi, K; Kobayashi, M; Kobayashi, S; Tadachi, M; Tomiyama, Y; Yamazaki, Y | 1 |
| Abdullah, NA; Johns, EJ; Khan, MA; Sattar, MA | 1 |
| Abdullah, NA; Armenia, A; Johns, EJ; Khan, MA; Sattar, MA | 1 |
| Abdullah, NA; Johns, EJ; Kazi, RN; Khan, AH; Munavvar, AS | 1 |
| Chung, YK; Jeong, YS; Lee, HK; Park, KE; Shin, IW; Sohn, JT; Sung, HJ | 1 |
| Chu, CC; Lin, MT; Shieh, JP; Wang, JJ | 1 |
| Kodama, D; Togari, A | 1 |
| Bockman, CS; Dang, HK; Gruber, DD; Scofield, MA; Wangemann, P; Witt, KM | 1 |
| Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD | 1 |
| Dementieva, RE; Fashutdinov, LI; Zefirov, TL; Ziyatdinova, NI | 1 |
| Armstrong, DL; Harry, GJ; Muessel, MJ; Storey, NM | 1 |
| Aréchiga-Figueroa, IA; Rodríguez-Menchaca, AA; Sánchez-Chapula, JA | 1 |
| Abdulla, MH; Abdullah, NA; Ahmad, A; Azam, M; Hashmi, F; Johns, EJ; Khan, SA; Sattar, MA | 1 |
2 review(s) available for chlorethylclonidine and clonidine
| Article | Year |
|---|---|
The alpha-adrenoceptor-mediated actions of chloroethylclonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 1997 |
Drug receptor mechanisms in smooth muscle: beta-chloroethylamine-sensitive and -resistant receptor mechanisms.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Guanosine Triphosphate; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Propylbenzilylcholine Mustard; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha-1; Receptors, Muscarinic; Signal Transduction | 1997 |
277 other study(ies) available for chlorethylclonidine and clonidine
| Article | Year |
|---|---|
Separation of putative alpha 1A- and alpha 1B-adrenoceptor mediated components in the tension response of the rat vas deferens to electrical field stimulation.
Topics: Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Suramin; Vas Deferens | 1992 |
Estradiol selectively regulates alpha 1B-noradrenergic receptors in the hypothalamus and preoptic area.
Topics: Animals; Clonidine; Cyclic AMP; Dioxanes; Estradiol; Female; Hypothalamus; Ovariectomy; Piperazines; Prazosin; Preoptic Area; Rats; Receptors, Adrenergic | 1992 |
[Modulation of heart rhythm by alpha-1 adrenoreceptors].
Topics: Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Electrocardiography; Heart Rate; Myocardial Ischemia; Phentolamine; Rats; Receptors, Adrenergic, alpha | 1992 |
[Alpha adrenoceptor subtypes in smooth muscles of rat pulmonary artery].
Topics: Animals; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1992 |
Subtype-selective alpha-1 adrenoceptor alkylation in the rat kidney and its effect on the vascular pressor response.
Topics: Adrenergic alpha-Antagonists; Alkylation; Animals; Clonidine; Imidazoles; Kidney; Male; Methoxamine; Phenylephrine; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Artery | 1992 |
Alpha 1-adrenoceptors in parotid cells: age does not alter the ratio of alpha 1A and alpha 1B subtypes.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Calcium; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Inosine Triphosphate; Male; Parotid Gland; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
Subtypes of alpha 1-adrenoceptors in DDT1 MF-2 and BC3H-1 clonal cell lines.
Topics: Adrenergic alpha-Antagonists; Binding, Competitive; Calcium; Cell Line; Clonidine; Inositol Phosphates; Muscle, Smooth; Norepinephrine; Phenethylamines; Piperazines; Radioligand Assay; Receptors, Adrenergic, alpha; Tetralones | 1992 |
Effect of chlorethylclonidine on arterial blood pressure and heart rate in the conscious rat.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Clonidine; Heart Rate; Injections, Intraperitoneal; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1992 |
Pharmacological properties of alpha 1-adrenoceptor-mediated vasoconstrictions in dog and monkey lingual arteries: evidence for subtypes of alpha 1-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Calcium Channels; Clonidine; Diltiazem; Dioxanes; Dogs; Dose-Response Relationship, Drug; Macaca; Muscle, Smooth, Vascular; Norepinephrine; Receptors, Adrenergic; Signal Transduction; Species Specificity; Tongue; Vasoconstriction | 1992 |
Evidence for a noradrenergic innervation to alpha 1A-adrenoceptors in rat kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium Channels; Clonidine; In Vitro Techniques; Kidney; Male; Nitrendipine; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Vasoconstriction | 1992 |
Vascular alpha-adrenoceptor affinity variation is not due to varying populations of subtypes distinguished by WB 4101 and chlorethylclonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Dioxanes; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptors, Adrenergic, alpha | 1992 |
The effects of electroconvulsive shock or imipramine on subtypes of alpha 1-adrenoceptors in the frontal cortex of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Clonidine; Dioxanes; Electroshock; Hippocampus; Imipramine; In Vitro Techniques; Kinetics; Male; Prazosin; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1992 |
The adrenoceptor agonist, SDZ NVI 085, discriminates between alpha 1A- and alpha 1B-adrenoceptor subtypes in vas deferens, kidney and aorta of the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; In Vitro Techniques; Isradipine; Kidney; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Oxazines; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vas Deferens; Vasoconstriction | 1992 |
Identification of alpha 1-adrenoceptor subtypes in the rat vas deferens: binding and functional studies.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Electric Stimulation; Epididymis; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Nifedipine; Norepinephrine; Oxathiins; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vas Deferens | 1992 |
Guinea pig hepatocyte alpha 1A-adrenoceptors: characterization, signal transduction and regulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Dose-Response Relationship, Drug; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Liver; Male; Pertussis Toxin; Phosphatidylinositols; Phosphorus Radioisotopes; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tritium; Virulence Factors, Bordetella | 1992 |
Pharmacological characterization of contractile responses induced by alpha 1-agonists, norepinephrine and clonidine, by selective antagonists of their subtypes in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Rabbits | 1992 |
Diversity of the pharmacological actions of some tolazoline analogues in human platelets and rat aorta.
Topics: Affinity Labels; Animals; Aorta, Thoracic; Blood Platelets; Clonidine; Humans; Rats; Receptors, Adrenergic, alpha; Tolazoline | 1991 |
Differences in alpha 1-adrenoceptor mechanisms for phenylephrine and tizanidine in rabbit thoracic aorta and common iliac artery.
Topics: Animals; Aorta, Thoracic; Clonidine; Dioxanes; Iliac Artery; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha; Tissue Distribution; Vasoconstriction | 1991 |
Abnormal automatic rhythms in ischemic Purkinje fibers are modulated by a specific alpha 1-adrenergic receptor subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Clonidine; Coronary Disease; Dioxanes; Dogs; Extracellular Space; Heart Rate; Phenylephrine; Propranolol; Purkinje Fibers; Receptors, Adrenergic, alpha | 1991 |
Relation between adrenergic neurogenic contraction and alpha 1-adrenoceptor subtypes in dog mesenteric and carotid arteries and rabbit carotid arteries.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Clonidine; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Sympathetic Nervous System | 1991 |
Comparative study of postsynaptic alpha-adrenoceptors in aorta obtained from human and other mammalian species.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Clonidine; Guinea Pigs; Humans; In Vitro Techniques; Male; Methoxamine; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1991 |
Interaction of imidazolines with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Drug Interactions; Imidazoles; Injections, Intraperitoneal; Male; Muscle, Smooth, Vascular; Phentolamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Regional distribution of alpha 1-adrenoceptor subtypes in rat kidney.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Cell Membrane; Clonidine; Dioxanes; Kidney; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Alpha 1-adrenoceptor subtypes in aorta (alpha 1A) and liver (alpha 1B).
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Liver; Membranes; Muscle, Smooth, Vascular; Phosphatidylinositols; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1991 |
An alpha-1-adrenergic receptor subtype is responsible for delayed afterdepolarizations and triggered activity during simulated ischemia and reperfusion of isolated canine Purkinje fibers.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Myocardial Reperfusion Injury; Phenylephrine; Purkinje Fibers; Receptors, Adrenergic, alpha | 1991 |
Evidence for a complex interaction between the subtypes of the alpha 1-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Kinetics; Male; Methoxamine; Muscle, Smooth, Vascular; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Interaction of subtype-selective antagonists with alpha 1-adrenergic receptor binding sites in rat tissues.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dioxanes; Kinetics; Male; Membranes; Phentolamine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Time Factors | 1991 |
Reduction of cardiac outward currents by alpha-1 adrenoceptor stimulation: a subtype-specific effect?
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dihydropyridines; Electrophysiology; Heart; Membrane Potentials; Myocardium; Phenylephrine; Piperazines; Propranolol; Rats; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1991 |
Potent inhibitory action of chlorethylclonidine on the positive inotropic effect and phosphoinositide hydrolysis mediated via myocardial alpha 1-adrenoceptors in the rabbit ventricular myocardium.
Topics: Adrenergic alpha-Antagonists; Animals; Bupranolol; Clonidine; Drug Interactions; Epinephrine; Heart Ventricles; Inositol Phosphates; Myocardial Contraction; Myocardium; Papillary Muscles; Phenylephrine; Phosphatidylinositols; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1991 |
Differences between full and partial alpha-adrenoceptor agonists in eliciting phasic and tonic types of responses in the longitudinal smooth muscle of the rat portal vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Calcium; Clonidine; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenoxybenzamine; Portal Vein; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Vasoconstriction | 1991 |
The alkylating prazosin analog SZL 49 inactivates both alpha 1A- and alpha 1B-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Drug Synergism; Hippocampus; Liver; Male; Membranes; Phenethylamines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones | 1991 |
Alpha 1A-adrenoceptors in rabbit bronchus.
Topics: Adrenergic alpha-Antagonists; Animals; Bronchi; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Piperazines; Rabbits; Receptors, Adrenergic, alpha | 1991 |
Subtypes of alpha 1-adrenoceptors involved in noradrenaline-induced contractions of rat thoracic aorta and dog carotid artery.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Carotid Arteries; Clonidine; Dogs; Electrophysiology; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Three distinct binding sites for [3H]-prazosin in the rat cerebral cortex.
Topics: Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Clonidine; In Vitro Techniques; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1991 |
Renal alpha 1-adrenergic receptor subtypes: MDCK-D1 cells, but not rat cortical membranes possess a single population of receptors.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Cell Membrane; Clonidine; Dogs; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Phosphatidylcholines; Phosphatidylinositols; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Tissue Distribution | 1991 |
Subtypes of alpha 1-adrenoceptors in rat blood vessels.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Clonidine; Dioxanes; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Artery | 1990 |
Pharmacological subclassification of alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Blood Vessels; Clonidine; Dioxanes; Dogs; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Yohimbine | 1990 |
Alpha 1 B- but not alpha 1 A-adrenoceptors mediate inositol phosphate generation.
Topics: Adrenergic alpha-Antagonists; Animals; Cerebral Cortex; Clonidine; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Species differences in chlorethylclonidine antagonism at vascular alpha-1 adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Rats; Receptors, Adrenergic, alpha; Species Specificity; Vasoconstriction | 1990 |
Agonist interaction with alkylation-sensitive and -resistant alpha-1 adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Binding Sites; Clonidine; Diltiazem; Dioxanes; Drug Interactions; Heart; Inositol Phosphates; Male; Muscle, Smooth, Vascular; Myocardium; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Thyrotrophin increases the alpha 1b-adrenergic receptors in rat thyroid gland in vivo.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Iodides; Male; Methimazole; Norepinephrine; Organ Size; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1990 |
[The identification and characteristics of subpopulations of alpha 1-adrenergic receptors].
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Calcium; Clonidine; Dioxanes; GTP-Binding Proteins; Liver; Microsomes; Phentolamine; Prazosin; Rats; Receptors, Adrenergic, alpha | 1990 |
Two pharmacologically distinct alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta: each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Binding Sites; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenethylamines; Phenoxybenzamine; Piperazines; Rabbits; Receptors, Adrenergic, alpha; Signal Transduction; Tetralones; Vasoconstriction | 1990 |
Alpha-1 adrenergic receptor binding and adrenergic-stimulated cyclic AMP production in rat cerebral cortex after chronic lithium treatment.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Cerebral Cortex; Chlorides; Clonidine; Cyclic AMP; Lithium; Lithium Chloride; Male; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Second Messenger Systems | 1990 |
Different desensitization mechanisms of two alpha 1-adrenoceptor subtypes in the contraction of rabbit aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenethylamines; Rabbits; Receptors, Adrenergic, alpha; Tetralones | 1990 |
Two distinct alpha 1-adrenoceptor subtypes involved in noradrenaline contraction of the rabbit thoracic aorta.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Female; In Vitro Techniques; Male; Norepinephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 1990 |
Characterization of alpha 1-adrenergic receptor subtypes linked to iodide efflux in rat FRTL cells.
Topics: Animals; Calcium; Cells, Cultured; Clonidine; Dose-Response Relationship, Drug; Iodides; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Thyroid Gland; Time Factors | 1990 |
Alpha 1-adrenergic receptor subtypes and formation of inositol phosphates in dispersed hepatocytes and renal cells.
Topics: Animals; Binding Sites; Cell Membrane; Clonidine; In Vitro Techniques; Inositol Phosphates; Kidney; Liver; Norepinephrine; Rats; Receptors, Adrenergic, alpha | 1990 |
The role of alpha 1-adrenoceptor subtypes in the regulation of arterial blood pressure.
Topics: Anesthesia; Animals; Aorta, Thoracic; Binding Sites; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; In Vitro Techniques; Male; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Pertussis toxin inhibits norepinephrine-stimulated inositol phosphate formation in primary brain cell cultures.
Topics: Animals; Brain; Calcium; Carbachol; Cells, Cultured; Clonidine; Cyclic AMP; Dioxanes; GTP-Binding Proteins; Inositol Phosphates; Norepinephrine; Pertussis Toxin; Phenethylamines; Prazosin; Rats; Receptors, Adrenergic, alpha; Tetralones; Virulence Factors, Bordetella; Yohimbine | 1990 |
Different pathways of [3H]inositol phosphate formation mediated by alpha 1a- and alpha 1b-adrenergic receptors.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Inositol Phosphates; Kidney; Liver; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Tritium | 1990 |
Specific alpha 1-adrenergic receptor subtypes modulate catecholamine-induced increases and decreases in ventricular automaticity.
Topics: Age Factors; Animals; Binding Sites; Cells, Cultured; Clonidine; Dioxanes; Dogs; Electrophysiology; Heart Ventricles; Inositol Phosphates; Norepinephrine; Purkinje Fibers; Receptors, Adrenergic, alpha; Stimulation, Chemical; Ventricular Function | 1990 |
Chloroethylclonidine unmasks a non-alpha-adrenoceptor noradrenaline binding site in the rat aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rats; Receptors, Adrenergic; Yohimbine | 1990 |
Differentiation of alpha 1-adrenergic receptors linked to phosphatidylinositol turnover and cyclic AMP accumulation in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkylating Agents; Animals; Aspirin; Brain; Brain Mapping; Calcium; Clonidine; Cyclic AMP; In Vitro Techniques; Indomethacin; Phenethylamines; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Tetralones | 1987 |
Glycogen phosphorylase activation by two different alpha 1-adrenergic receptor subtypes: methoxamine selectively stimulates a putative alpha 1-adrenergic receptor subtype (alpha 1a) that couples with Ca2+ influx.
Topics: Animals; Calcium; Clonidine; Enzyme Activation; Epinephrine; In Vitro Techniques; Inositol Phosphates; Male; Methoxamine; Phenethylamines; Phenylephrine; Phosphorylases; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetralones | 1989 |
Regional variations in alpha 1-adrenergic receptor subtypes in rat brain.
Topics: Animals; Binding, Competitive; Brain; Clonidine; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Regression Analysis | 1989 |
Central alpha 1 adrenoceptor subtypes in narcolepsy-cataplexy: a disorder of REM sleep.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Cataplexy; Clonidine; Dioxanes; Dogs; Narcolepsy; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Sleep, REM | 1989 |
Comparison of alpha 1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101.
Topics: Animals; Clonidine; Dioxanes; Dioxins; Hippocampus; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Osmolar Concentration; Rats; Receptors, Adrenergic, alpha; Solubility; Spleen; Tissue Distribution; Vas Deferens | 1988 |
Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Hippocampus; Liver; Male; Phenethylamines; Rats; Receptors, Adrenergic, alpha; Spleen; Tetralones; Tissue Distribution; Vas Deferens | 1987 |
Functional analyses of alpha 1-adrenoceptor subtypes in rat hypothalamic ventromedial nucleus neurons.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Hypothalamus, Middle; In Vitro Techniques; Neurons; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1995 |
Alpha 1-adrenoceptor subtype affinities of drugs for the treatment of prostatic hypertrophy. Evidence for heterogeneity of chloroethylclonidine-resistant rat renal alpha 1-adrenoceptor.
Topics: Alkylating Agents; Animals; Centrifugation, Density Gradient; Cerebral Cortex; Clonidine; Drug Resistance; In Vitro Techniques; Inositol Phosphates; Kidney; Liver; Male; Membranes; Prostatic Hyperplasia; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1993 |
Evidence for an alpha 1-adrenoceptor subtype mediating adrenergic vasoconstriction in Wistar normotensive and stroke-prone spontaneously hypertensive rat kidney.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Cerebrovascular Disorders; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Kidney; Male; Methoxamine; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-1; Renal Circulation; Sympathetic Nervous System; Vasoconstriction | 1994 |
Alpha 1-adrenoceptor subtypes mediating adrenergic vasoconstriction in kidney, one-clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Clonidine; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renovascular; Kidney; Male; Methoxamine; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Vasoconstriction | 1994 |
Role of alpha 1A- and alpha 1B-adrenoceptors in phenylephrine-induced positive inotropic response in isolated rat left atrium.
Topics: Adrenergic alpha-Antagonists; Animals; Atrial Function; Binding, Competitive; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Inositol Phosphates; Male; Myocardial Contraction; Phenethylamines; Phenylephrine; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Tetralones | 1994 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Hypertension; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Vascular Resistance | 1995 |
Evidence for a functional alpha 1A- (alpha 1C-) adrenoceptor mediating contraction of the rat epididymal vas deferens and an alpha 1B-adrenoceptor mediating contraction of the rat spleen.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Cocaine; Epididymis; Estradiol; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Vasoconstrictor Agents | 1995 |
Renal aging change of alpha 1-adrenoceptor in Wistar rats.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Autoradiography; Binding Sites; Clonidine; Kidney; Kinetics; Male; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1995 |
Alpha 1A-adrenoceptor subtype effectively increases Ca(2+)-sensitivity for contraction in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Aorta, Thoracic; Calcium; Carbazoles; Clonidine; Cytosol; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Rabbits; Receptors, Adrenergic, alpha-1; Sensitivity and Specificity | 1995 |
Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action.
Topics: Adrenergic alpha-Antagonists; Calcium; Clonidine; Contraceptive Agents, Male; Cystamine; Humans; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Prazosin; Vas Deferens | 1995 |
Characterization of alpha 1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulation.
Topics: Adrenergic Antagonists; Animals; Clonidine; Electric Stimulation; Humans; Hyperplasia; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens; Yohimbine | 1995 |
KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; CHO Cells; Clonidine; Cloning, Molecular; Cricetinae; Humans; Indoles; Norepinephrine; Prazosin; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Sulfonamides; Tamsulosin | 1995 |
Further evidence that the classical alpha 1A- and cloned alpha 1c-adrenoceptors are the same subtype.
Topics: Animals; Binding Sites; Cattle; Clonidine; HeLa Cells; Humans; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins | 1995 |
Alpha 1-adrenoceptor subtypes and inositol phosphates production in heart ventricles of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Heart Ventricles; Hypertension; Inositol Phosphates; Male; Myocardium; Norepinephrine; Prazosin; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha | 1993 |
Characterization of the alpha 1-adrenoceptors of dog liver: predominance of the alpha 1A-subtype.
Topics: Animals; Binding, Competitive; Clonidine; Dogs; Liver; Phenethylamines; Receptors, Adrenergic, alpha-1; Tetralones | 1995 |
Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Atropine; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Mice; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Yohimbine | 1995 |
Alpha 1a-adrenergic receptor mediated positive chronotropic effect in right atria isolated from rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Atrial Function; Clonidine; Dioxanes; Heart Atria; Heart Rate; In Vitro Techniques; Male; Phenoxybenzamine; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1994 |
The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Aorta, Thoracic; Clonidine; Dioxanes; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred WKY | 1995 |
Alpha 1-adrenoceptor responsiveness in the aging aorta.
Topics: Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha-1 | 1995 |
Mediation of noradrenaline-induced contractions of rat aorta by the alpha 1B-adrenoceptor subtype.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Computer Simulation; Hippocampus; In Vitro Techniques; Liver; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regression Analysis; Spiperone; Stereoisomerism; Sulfonamides | 1995 |
Effect of receptor density on the receptor-effector coupling: use of cloned and stably expressed alpha 1B-adrenoceptors in CHO cells.
Topics: Animals; Calcium; CHO Cells; Clonidine; Cricetinae; Norepinephrine; Phenethylamines; Phenoxybenzamine; Radioligand Assay; Receptors, Adrenergic, alpha-1; Tetralones | 1995 |
Pharmacological characterization of alpha 1-adrenoceptor subtypes in rat heart: a binding study.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Binding, Competitive; Clonidine; Heart; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Myocardium; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1995 |
The pharmacological profile of cloned and stably expressed alpha 1b-adrenoceptor in CHO cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Base Sequence; Calcium; Cell Membrane; CHO Cells; Clonidine; Cloning, Molecular; Cricetinae; DNA; Iodine Radioisotopes; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Receptors, Adrenergic, alpha-1; Signal Transduction; Transfection | 1994 |
Pharmacological evidence of distinct alpha 1-adrenoceptor subtypes mediating the contraction of human prostatic urethra and peripheral artery.
Topics: Aged; Aged, 80 and over; Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Phenylephrine; Receptors, Adrenergic, alpha-1; Urethra; Vasoconstriction | 1994 |
Alpha 1A-adrenoceptor subtype mediates contraction of the rat urethra.
Topics: Aminoquinolines; Animals; Calcium; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Idazoxan; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Urethra | 1994 |
Functional identification of alpha 1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Animals; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 1994 |
Alpha 1B-receptors and intracellular calcium mediate sympathetic nerve induced constriction of rat irideal blood vessels.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Caffeine; Calcium; Calcium Channel Blockers; Clonidine; Electric Stimulation; Female; In Vitro Techniques; Iris; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sympathetic Nervous System; Synapses | 1994 |
Interactions of chloroethylclonidine with rauwolscine- and prazosin-sensitive adrenoceptors in dog saphenous vein.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Clonidine; Dioxanes; Dogs; Extracellular Space; In Vitro Techniques; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Prazosin; Saphenous Vein; Yohimbine | 1994 |
Chloroethylclonidine irreversibly activates postjunctional alpha 2-adrenoceptors in the dog saphenous vein.
Topics: Adrenergic alpha-Agonists; Alkylating Agents; Animals; Brimonidine Tartrate; Clonidine; Cocaine; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Junction; Phenylephrine; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Saphenous Vein | 1993 |
Alpha 1-adrenoceptor subtype involved in the positive inotropic response to phenylephrine in rat atria.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha | 1993 |
Chloroethylclonidine discriminates between alpha 1A- and alpha 1B-adrenoceptors in the presence of guanosine 5'-triphosphate in rabbit thoracic aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding Sites; Clonidine; Dioxanes; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1993 |
Sympathetic transmission to the dilator muscle of the rat iris.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Iris; Membrane Potentials; Neuroeffector Junction; Norepinephrine; Parasympathetic Nervous System; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sympathetic Nervous System; Synaptic Transmission; Synaptic Vesicles; Yohimbine | 1993 |
Characterization of alpha 1-adrenoceptor subtypes in prostate and prostatic urethra of rat, rabbit, dog and man.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Binding Sites; Clonidine; Dogs; Humans; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Prazosin; Prostate; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Species Specificity; Urethra | 1993 |
Effects of age on alpha 1-adrenoceptor subtypes in the heart ventricular muscle of the rat.
Topics: Adrenergic alpha-Antagonists; Aging; Alkylating Agents; Animals; Binding, Competitive; Clonidine; Dioxanes; In Vitro Techniques; Myocardium; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1993 |
Characterization of the alpha 1-adrenoceptors of the rat prostate gland.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Spleen; Vas Deferens | 1993 |
Identification of alpha 1-adrenoceptor subtypes in rat renal proximal tubules.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Kidney Tubules; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Aminophylline preferentially inhibits chloroethylclonidine-insensitive alpha-adrenoceptor-mediated contractions in rat aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminophylline; Animals; Aorta, Thoracic; Calcium; Calcium Radioisotopes; Clonidine; Female; Gallopamil; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Oxymetazoline; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1993 |
Functional distribution and role of alpha-1 adrenoceptor subtypes in the mesenteric vasculature of the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1994 |
Effects of WB4101 and chloroethylclonidine on the positive and negative inotropic actions of phenylephrine in rat cardiac muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Drug Antagonism; In Vitro Techniques; Male; Myocardial Contraction; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1994 |
Is SDZ NVI-085 an alpha 1-adrenoceptor subtype-selective agonist?
Topics: Adrenergic alpha-Agonists; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cattle; Cell Line; Cerebral Cortex; Clonidine; In Vitro Techniques; Inositol Phosphates; Kidney; Norepinephrine; Oxazines; Prazosin; Rats; Receptors, Adrenergic, alpha; Spleen; Transfection | 1994 |
[The modulation of anomalous automatism in ischemic Purkinje fibers by a specific subclass of alpha 1-adrenoblockers].
Topics: Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Heart Rate; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion; Perfusion; Purkinje Fibers; Receptors, Adrenergic, alpha-1 | 1993 |
Receptor-effector coupling pathway for alpha 1-adrenergic modulation of abnormal automaticity in 'ischemic' canine Purkinje fibers.
Topics: Adrenergic alpha-Antagonists; Animals; Barium; Clonidine; Dioxanes; Dogs; Membrane Potentials; Myocardial Ischemia; Pertussis Toxin; Phenylephrine; Purkinje Fibers; Receptors, Adrenergic, alpha-1; Virulence Factors, Bordetella | 1994 |
Selective enrichment with alpha 1A- and alpha 1B-adrenoceptor subtypes in rat brain cortical membranes.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Binding Sites; Cerebral Cortex; Clonidine; Cystamine; Dihydropyridines; Dioxanes; Phenoxybenzamine; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha | 1994 |
Characterization of the hepatic alpha 1B-adrenoceptors of rats, mice and hamsters.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Clonidine; Cricetinae; Dihydropyridines; Liver; Male; Mesocricetus; Mice; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Species Specificity | 1994 |
Radioligand binding studies of alpha 1-adrenoceptor subtypes in rat heart.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cadmium; Cadmium Chloride; Calcium; Chlorides; Clonidine; Epinephrine; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Piperazines; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1994 |
Functional studies on alpha 1-adrenoceptor subtypes mediating inotropic effects in rat right ventricle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cadmium; Cadmium Chloride; Calcium; Chlorides; Clonidine; Epinephrine; Heart Ventricles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Nitrendipine; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Stimulation, Chemical; Vas Deferens | 1994 |
A new alpha 1-adrenergic receptor subtype with low affinity for 5-methyl-urapidil but insensitive to chlorethylclonidine.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Male; Myocardium; Phenethylamines; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetralones | 1993 |
Investigation of alpha 1-adrenoceptor subtypes in canine aorta, using alkylating agents.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Aorta; Binding, Competitive; Clonidine; Dioxanes; Dogs; Female; In Vitro Techniques; Male; Mesenteric Veins; Muscle, Smooth, Vascular; Oxymetazoline; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1 | 1994 |
WB4101- and CEC-sensitive positive inotropic actions of phenylephrine in rat cardiac muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Osmolar Concentration; Papillary Muscles; Phenylephrine; Rats; Rats, Sprague-Dawley | 1994 |
Refractory period response of cardiac Purkinje tissue to alpha 1- and alpha 2-adrenergic influences.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dioxanes; Dogs; Female; Male; Norepinephrine; Phenylephrine; Purkinje Fibers; Receptors, Adrenergic, alpha; Refractory Period, Electrophysiological | 1994 |
Identification of the mRNA for the novel alpha 1D-adrenoceptor and two other alpha 1-adrenoceptors in vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; In Situ Hybridization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Messenger | 1994 |
alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Body Weight; Clonidine; Coronary Circulation; Enzyme Activation; Female; Heart; Heart Rate; In Vitro Techniques; Male; Methoxamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Organ Size; Phenoxybenzamine; Phenylephrine; Polymyxin B; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha-1 | 1994 |
Alpha 1-adrenoceptor subtype(s) mediating noradrenaline-induced contractions of the guinea-pig aorta.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Dioxanes; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Oxazines; Prazosin; Receptors, Adrenergic, alpha-1 | 1994 |
Accelerated resensitization of the D1 dopamine receptor-mediated response in cultured cortical and striatal neurons from the rat: respective role of alpha 1-adrenergic and N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Cyclic AMP; Dopamine; Down-Regulation; Glutamic Acid; Isoproterenol; Methoxamine; Neurons; Prazosin; Prefrontal Cortex; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Visual Cortex | 1994 |
The rat homologue of the bovine alpha 1c-adrenergic receptor shows the pharmacological properties of the classical alpha 1A subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Cattle; Cell Line; Clonidine; Cloning, Molecular; DNA, Complementary; Enzyme Activation; Gene Expression; Glycosylation; Humans; Molecular Sequence Data; Oligonucleotide Probes; Open Reading Frames; Phosphorylation; Rats; Receptors, Adrenergic, alpha; Ribonucleases; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Type C Phospholipases | 1994 |
Coronary artery constriction in rats affects the activation of alpha 1 adrenergic receptors in cardiac myocytes.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Base Sequence; Calcium; Cell Size; Cells, Cultured; Clonidine; Constriction; Coronary Vessels; Cytosol; Dioxanes; Inositol Phosphates; Male; Molecular Sequence Data; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 1994 |
Comparative study on alpha 1-adrenoceptor antagonist binding in human prostate and aorta.
Topics: Adrenergic alpha-Antagonists; Aged; Aorta; Binding Sites; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Kinetics; Male; Middle Aged; Naphthalenes; Piperazines; Prazosin; Prostate; Sulfonamides; Tamsulosin | 1994 |
[Pharmacological study on functional significance of alpha 1-adrenoceptor subtypes in mammalian ventricular myocardium].
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Ventricles; Hydrolysis; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Phosphatidylinositols; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Stimulation, Chemical | 1994 |
Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat.
Topics: Animals; Blood Pressure; Blood Vessels; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation; Idazoxan; Male; Nifedipine; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Sympathetic Nervous System | 1994 |
A heterogeneous population of alpha 1 adrenergic receptors mediates contraction of human corpus cavernosum smooth muscle to norepinephrine.
Topics: Alkylating Agents; Clonidine; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Penis; Prazosin; Receptors, Adrenergic, alpha-1 | 1995 |
Regulation of atrial natriuretic peptide secretion by alpha 1-adrenergic receptors: the role of different second messenger pathways.
Topics: Animals; Atrial Natriuretic Factor; Calcium; Calmodulin; Cells, Cultured; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Heart; Male; Muscle Proteins; Myocardial Contraction; Myocardium; Norepinephrine; Propranolol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Second Messenger Systems; Secretory Rate; Thionucleotides; Trifluoperazine | 1994 |
Alpha 1 adrenoceptor subtypes in the human prostate.
Topics: Adrenergic alpha-Antagonists; Aged; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Middle Aged; Phenethylamines; Piperazines; Prostate; Receptors, Adrenergic, alpha; Tetralones | 1993 |
Chloroethylclonidine: an irreversible agonist at prejunctional alpha 2-adrenoceptors in rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Rats; Rats, Wistar; Tritium; Vas Deferens | 1993 |
Receptor subtype involved and mechanism of norepinephrine-induced stimulation of glutamate uptake into primary cultures of rat brain astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Barium; Biological Transport; Brain; Cells, Cultured; Clonidine; Glutamates; Glutamic Acid; Glycoproteins; Norepinephrine; Pertussis Toxin; Rats; Receptors, Adrenergic, alpha; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Alpha 1b-adrenoceptor-mediated stimulation of Na-K pump current in adult rat ventricular myocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Male; Myocardium; Ouabain; Phenoxybenzamine; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Sodium-Potassium-Exchanging ATPase; Ventricular Function, Left | 1993 |
Pharmacological characterization of two distinct alpha 1-adrenoceptor subtypes in rabbit thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenoxybenzamine; Prazosin; Rabbits; Receptors, Adrenergic, alpha | 1993 |
The alpha-adrenoceptor subtype mediating the tension of human prostatic smooth muscle.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Binding, Competitive; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Phenylephrine; Piperazines; Prostate; Receptors, Adrenergic, alpha | 1993 |
Modulation of delayed afterdepolarisations by alpha 1 adrenergic receptor subtypes.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Clonidine; Culture Techniques; Dioxanes; Dogs; Heart; Ouabain; Phenylephrine; Purkinje Fibers; Receptors, Adrenergic, alpha | 1993 |
Cardiovascular effects of chloroethylclonidine, an irreversible alpha 1B-adrenoceptor antagonist, in the unanesthetized rat: a pharmacological analysis in vivo and in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Rats; Receptors, Adrenergic, alpha; Vasoconstriction | 1993 |
Alpha 1B-adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Cyclic AMP; Dioxanes; In Vitro Techniques; Liver; Male; Methoxamine; Norepinephrine; Pertussis Toxin; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella | 1993 |
Alpha-1 adrenoceptor subtypes in canine aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Binding Sites; Clonidine; Dogs; Oxathiins; Prazosin; Receptors, Adrenergic, alpha; Structure-Activity Relationship | 1993 |
Alpha 1-adrenoceptor subtype in the rat prostate is preferentially the alpha 1A type.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Aorta; Binding Sites; Clonidine; In Vitro Techniques; Male; Prostate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Stereoisomerism; Sulfonamides; Tamsulosin | 1993 |
Relation between alpha 1-adrenoceptor subtypes and noradrenaline-induced contraction in rat portal vein smooth muscle.
Topics: Acetonitriles; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Clonidine; Dioxanes; Horses; In Vitro Techniques; Isometric Contraction; Kinetics; Microsomes; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Prazosin; Rats; Receptors, Adrenergic, alpha-1 | 1993 |
Alpha 1-adrenoceptors in the human prostatic urethra are different from those of the human peripheral arteries.
Topics: Arteries; Atropine; Clonidine; Dioxanes; Humans; Iliac Artery; Isometric Contraction; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Urethra; Yohimbine | 1993 |
Regulation of alpha 1B-adrenergic receptor half-life: protein synthesis dependence and effect of norepinephrine.
Topics: Alkylating Agents; Animals; Aorta; Cells, Cultured; Clonidine; Cycloheximide; Down-Regulation; Half-Life; Muscle Proteins; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptors, Adrenergic, beta | 1994 |
The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.
Topics: Animals; CHO Cells; Clonidine; Cricetinae; Humans; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Prostate; Receptors, Adrenergic, alpha; Recombinant Proteins | 1994 |
Alpha 1A- and alpha 1B-adrenoceptor-mediated positive chronotropic effects on isolated rat atrium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Clonidine; Heart Atria; Heart Rate; In Vitro Techniques; Isoquinolines; Male; Phenylephrine; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Stimulation, Chemical | 1993 |
The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat.
Topics: Animals; Blood Pressure; Clonidine; Consciousness; Drug Resistance; Hemodynamics; Hindlimb; Male; Mesenteric Arteries; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sensitivity and Specificity; Vascular Resistance | 1993 |
Selective irreversible binding of chloroethylclonidine at alpha 1- and alpha 2-adrenoceptor subtypes.
Topics: 3T3 Cells; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding, Competitive; Cells, Cultured; Clonidine; Humans; Mice; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2 | 1993 |
Alpha 1-adrenoceptor subtypes mediating the norepinephrine-induced contractile response in the rat vas deferens.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alkylating Agents; Animals; Clonidine; Epididymis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperazines; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Ryanodine; Vas Deferens | 1993 |
Characterization of adrenergic receptors in membranes from the rat seminal vesicle.
Topics: Animals; Clonidine; Dihydroalprenolol; Epinephrine; Guanine Nucleotides; In Vitro Techniques; Male; Membranes; Parasympathomimetics; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Seminal Vesicles | 1993 |
Comparison of alpha 1-adrenergic receptor subtypes and signal transduction in SK-N-MC and NB41A3 neuronal cell lines.
Topics: Animals; Calcium; Clonidine; Humans; Mice; Neurons; Norepinephrine; Phosphatidylinositols; Radioligand Assay; Receptors, Adrenergic, alpha; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 1993 |
Characterization of the alpha 1A-adrenoceptors of guinea pig liver membranes: studies using 5-[3H]methylurapidil.
Topics: Alkylating Agents; Animals; Binding, Competitive; Clonidine; Guinea Pigs; In Vitro Techniques; Liver; Male; Piperazines; Radioligand Assay; Receptors, Adrenergic, alpha | 1993 |
Regulation of vascular smooth muscle growth by alpha 1-adrenoreceptor subtypes in vitro and in situ.
Topics: Actins; Adrenergic alpha-Antagonists; Animals; Aorta; Cell Division; Cells, Cultured; Clonidine; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; RNA, Messenger; Venae Cavae | 1995 |
Alpha 1B-adrenergic receptors in rat renal microvessels.
Topics: Affinity Labels; Alkylating Agents; Animals; Azides; Binding Sites; Blood Vessels; Clonidine; Male; Microcirculation; Prazosin; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Renal Circulation; RNA, Messenger | 1995 |
Investigation of the actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine | 1995 |
Alpha 1A-adrenoceptor-mediated contractile responses of the human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Calcium; Clonidine; Extracellular Space; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenylephrine; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vas Deferens | 1995 |
Comparison of guinea-pig, bovine and rat alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cattle; Clonidine; Guinea Pigs; In Vitro Techniques; Male; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Species Specificity; Tritium | 1996 |
Unusual alpha-adrenoceptor subtype in canine saphenous vein: comparison to mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dogs; Female; Humans; In Vitro Techniques; Male; Mesenteric Veins; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Adrenergic, alpha; Saphenous Vein; Yohimbine | 1996 |
Differences of desensitization and hypersensitization between alpha 1A- and alpha 1B-adrenoceptors in rat isolated blood vessels.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Clonidine; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Renal Artery; Vasoconstriction | 1995 |
Chloroethylclonidine increases the incidence of lethal arrhythmias during coronary occlusion in anesthetized dogs.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Female; Male; Myocardial Ischemia; Receptors, Adrenergic, alpha-1 | 1995 |
alpha1-Adrenoceptor subtypes mediating antinatriuresis in Wistar and stroke-prone spontaneously hypertensive rats.
Topics: Animals; Clonidine; Diuresis; Hypertension; Male; Natriuresis; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1995 |
The positive inotropic effect of alpha 1A-adrenoceptor stimulation is inhibited by 4-aminopyridine.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Cardiotonic Agents; Clonidine; Dioxanes; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Staurosporine | 1996 |
Rat pineal alpha 1-adrenoceptor subtypes: studies using radioligand binding and reverse transcription-polymerase chain reaction analysis.
Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dioxanes; Male; Phenethylamines; Pineal Gland; Polymerase Chain Reaction; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Tetralones; Transcription, Genetic | 1996 |
Pharmacological characterization of alpha 1-adrenoceptors in porcine uterine artery.
Topics: Animals; Arteries; Calcium; Clonidine; Estrus; Female; In Vitro Techniques; Nifedipine; Norepinephrine; Phenylephrine; Pregnancy; Pregnancy, Animal; Receptors, Adrenergic, alpha-1; Swine; Uterus | 1996 |
Functional evidence for an alpha 1B-adrenoceptor mediating contraction of the mouse spleen.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Male; Mice; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Spleen | 1996 |
(+/-)-tamsulosin, an alpha 1A-adrenoceptor antagonist, inhibits the positive inotropic effect but not the accumulation of inositol phosphates in rabbit heart.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Inositol Phosphates; Male; Myocardial Contraction; Myocardium; Oxymetazoline; Rabbits; Sulfonamides; Tamsulosin; Tritium | 1996 |
Alpha 1-adrenoceptor subtype distribution and the coupling to phosphoinositide hydrolysis in rat and rabbit ventricular myocardium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Heart Ventricles; Hydrolysis; Kinetics; Lithium Chloride; Male; Myocardium; Phosphatidylinositols; Prazosin; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tritium | 1996 |
Alpha 1-adrenoceptor subtypes mediating inotropic and electrophysiological effects in mammalian myocardium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Electric Conductivity; Electrophysiology; Female; Heart; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Rabbits; Rats; Receptors, Adrenergic, alpha | 1996 |
Hypoxia/reoxygenation selectively impairs alpha 1b-adrenoceptor function in small mesenteric arteries.
Topics: Adrenergic alpha-Antagonists; Aerobiosis; Animals; Catalase; Clonidine; Dioxanes; Hypoxia; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Superoxide Dismutase; Yohimbine | 1996 |
Characterization of alpha-adrenoceptor activity in term-newborn piglet mesentery.
Topics: Animals; Animals, Newborn; Benzazepines; Clonidine; Dioxanes; Female; Male; Mesenteric Arteries; Receptors, Adrenergic, alpha; Swine; Vasoconstriction | 1996 |
Functional characterisation of alpha 1-adrenoceptor subtypes mediating noradrenaline-induced inositol phosphate formation in rat thalamus slices.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Dioxanes; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Thalamus | 1996 |
Noradrenaline-induced inositol phosphate formation in rat striatum is mediated by alpha 1A-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkylating Agents; Animals; Calcium; Calcium Channel Blockers; Clonidine; Dihydropyridines; Dioxanes; In Vitro Techniques; Inositol Phosphates; Male; Neostriatum; Norepinephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1996 |
Alpha 1-adrenergic receptor antibodies in patients with primary hypertension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Amino Acid Sequence; Animals; Animals, Newborn; Autoantibodies; Blood Proteins; Cells, Cultured; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Heart; Humans; Hypertension; Male; Middle Aged; Molecular Sequence Data; Peptides; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance | 1997 |
alpha1-Adrenoceptor subtypes mediating the contraction of arteries in spontaneously hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Arteries; Clonidine; Femoral Artery; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1 | 1995 |
Intracellular Ca2+ and contractile responses to alpha 1-adrenoceptor subtype activation in rat aortic vascular smooth muscle.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Calcium; Clonidine; Dioxanes; Female; Fluorescent Dyes; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley | 1997 |
Evidence for an age-dependent functional expression of alpha 1D-adrenoceptors in the rat vasculature.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Blood Pressure; Blood Vessels; Clonidine; Male; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Alpha 1D- and alpha 1A-adrenoceptors mediate contraction in rat renal artery.
Topics: Animals; Clonidine; Male; Muscle Contraction; Norepinephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Renal Artery | 1997 |
Pharmacological classification of alpha 1-adrenoceptors mediating contractions of rabbit isolated ear artery: comparison with rat isolated thoracic aorta.
Topics: Animals; Aorta, Thoracic; Clonidine; Dose-Response Relationship, Drug; Ear; In Vitro Techniques; Male; Piperazines; Rabbits; Rats; Receptors, Adrenergic, alpha-1; Vasoconstriction | 1997 |
Alpha 1-adrenoceptor subtypes involved in increased 86Rb+ influx rate and inositol 1,4,5-trisphosphate mass in adult rat cardiomyocytes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cells, Cultured; Clonidine; Dioxanes; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Myocardium; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Rubidium Radioisotopes | 1997 |
Heterogeneity and complexity of alpha 1-adrenoceptors in the ovine uterine artery and umbilical vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Clonidine; Dioxanes; Drug Interactions; Drug Synergism; Female; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Prazosin; Pregnancy; Receptors, Adrenergic, alpha-1; Sheep; Umbilical Veins; Uterus; Vasoconstriction | 1997 |
Alpha 1-adrenoceptor subtype involved in the positive and negative inotropic responses to phenylephrine in rat papillary muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Carcinogens; Cardiotonic Agents; Clonidine; Dioxanes; Electrophysiology; In Vitro Techniques; Myocardial Contraction; Nifedipine; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Functional change of the balance between alpha 1A and alpha 1B adrenoceptor populations after transplantation of the vas deferens to the intestine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Intestinal Mucosa; Isradipine; Male; Muscle Contraction; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Vas Deferens | 1997 |
Subtyping of alpha1-adrenoceptors responsible for the contractile response in the rat corpus cavernosum.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Penis; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1997 |
Characterization of subtype of alpha1-adrenoceptor mediating vasoconstriction in perfused rat hind limb.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cell Line; Clonidine; Cloning, Molecular; Dioxanes; Dose-Response Relationship, Drug; Extremities; Humans; Indoles; Norepinephrine; Perfusion; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Vasoconstriction | 1997 |
Involvement of alpha1B-adrenoceptors in the positive inotropic effect of endogenous noradrenaline in rabbit myocardium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Female; Male; Myocardial Contraction; Norepinephrine; Papillary Muscles; Phenylephrine; Propranolol; Rabbits; Receptors, Adrenergic, alpha-1; Stimulation, Chemical; Tyramine | 1997 |
Alpha 1-adrenoceptor mediated activation of Na/K/2Cl cotransport and K+ channels in the rat heart involves different receptor subtypes.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Bumetanide; Carrier Proteins; Chlorides; Clonidine; Heart; In Vitro Techniques; Male; Myocardium; Phenylephrine; Piperazines; Potassium; Potassium Channels; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sodium; Sodium-Potassium-Chloride Symporters | 1997 |
Alpha-adrenoceptor-mediated prejunctional effects of chloroethylclonidine in the canine saphenous vein.
Topics: Adrenergic alpha-Antagonists; Animals; Autoreceptors; Brimonidine Tartrate; Clonidine; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Saphenous Vein; Yohimbine | 1997 |
Infarct size-reducing effect of ischemic preconditioning is related to alpha1b-adrenoceptors but not to alpha1a-adrenoceptors in rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Ischemic Preconditioning, Myocardial; Male; Phenoxybenzamine; Piperazines; Quinazolines; Rabbits; Receptors, Adrenergic, alpha-1 | 1997 |
Subtype-specific differences in subcellular localization of alpha1-adrenoceptors: chlorethylclonidine preferentially alkylates the accessible cell surface alpha1-adrenoceptors irrespective of the subtype.
Topics: Adrenergic alpha-Antagonists; Alkylation; Animals; Chlorocebus aethiops; Clonidine; COS Cells; Flow Cytometry; Fluorescent Antibody Technique; Microscopy, Fluorescence; Receptors, Adrenergic, alpha-1; Subcellular Fractions | 1997 |
The alpha1B-adrenergic receptor subtype activates the phospholipase C signaling pathway in rat myometrium at parturition.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Membrane; Clonidine; Dioxanes; Female; Guanylyl Imidodiphosphate; Labor, Obstetric; Myometrium; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Signal Transduction; Type C Phospholipases | 1997 |
Chloroethylclonidine and alpha-adrenoceptor agonist interaction in blood vessels following heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Dogs; Dose-Response Relationship, Drug; Heart Failure; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Saphenous Vein | 1997 |
Further investigation of the alpha-adrenoceptor-mediated actions of chloroethylclonidine in rat aorta.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Age Factors; Animals; Aorta; Clonidine; In Vitro Techniques; Male; Norepinephrine; Phenoxybenzamine; Rats; Rats, Wistar; Spleen | 1997 |
Investigation of alpha1-adrenoceptor subtypes mediating vasoconstriction in rabbit cutaneous resistance arteries.
Topics: Acetonitriles; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-1; Skin; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 1997 |
Characterization of alpha-adrenoceptors in canine mesenteric vein.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Dogs; Female; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Yohimbine | 1997 |
Effects of alpha 1-adrenoreceptor subtype blockade on ischemia-reperfusion injury.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Energy Metabolism; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Quinazolines; Rats; Rats, Sprague-Dawley | 1997 |
Chloroethylclonidine is a partial alpha1A-adrenoceptor agonist in cells expressing recombinant alpha1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Calcium; Cell Line; Clonidine; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Recombinant Proteins | 1997 |
Expression and function of alpha1-adrenoceptor subtypes in the porcine renal artery.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Base Sequence; Calcium; Clonidine; Female; Gene Expression; Male; Molecular Sequence Data; Muscle Contraction; Phenylephrine; Receptors, Adrenergic, alpha-1; Renal Artery; RNA, Messenger; Swine | 1998 |
Chloroethylclonidine binds irreversibly to exposed cysteines in the fifth membrane-spanning domain of the human alpha2A-adrenergic receptor.
Topics: Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Binding Sites; Clonidine; Cysteine; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Transfection | 1998 |
Interaction between alpha-1 adrenergic and vagal effects on cardiac rate and repolarization.
Topics: Animals; Clonidine; Dioxanes; Electrocardiography; GTP-Binding Proteins; Guinea Pigs; Heart; Heart Rate; Male; Membrane Potentials; Phenylephrine; Receptors, Adrenergic, alpha-1; Vagus Nerve | 1998 |
Characterization of alpha1-adrenoceptor subtypes in facilitation of rat spinal motoneuron activity.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Bridged-Ring Compounds; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Male; Methoxamine; Motor Neurons; Norepinephrine; Oxazines; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Spinal Cord | 1997 |
Alteration of alpha1-adrenoceptor subtypes in aortas of 12-month-old spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Hypertension; Indoles; Male; Muscle Contraction; Norepinephrine; Piperazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Ribonucleases | 1998 |
Opposing effects of alpha 1-adrenergic receptor subtypes on Ca2+ and pH homeostasis in rat cardiac myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Dioxanes; Drug Combinations; Drug Synergism; Fluorescent Dyes; Homeostasis; Hydrogen; Hydrogen-Ion Concentration; Indoles; Male; Myocardial Contraction; Myocardium; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 1998 |
Pharmacological and immunocytochemical characterization of subtypes of alpha-1 adrenoceptors in dog aorta.
Topics: Animals; Aorta; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Immunohistochemistry; Indoles; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Spiro Compounds | 1998 |
alpha1-Adrenoceptor-mediated phosphorylation of myosin in rat-tail arterial smooth muscle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Azepines; Calcium; Clonidine; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Serine; Tail | 1997 |
Subtype-specific differences in subcellular localization and chlorethylclonidine inactivation of alpha1-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; COS Cells; Epitopes; GTP-Binding Proteins; Iodine Radioisotopes; Phenethylamines; Receptors, Adrenergic, alpha-1; Subcellular Fractions; Substrate Specificity; Tetralones; Transfection | 1998 |
Alpha1-adrenergic stimulation of sarcolemmal Na+-H+ exchanger activity in rat ventricular myocytes: evidence for selective mediation by the alpha1A-adrenoceptor subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cattle; Clonidine; Dioxanes; Heart Ventricles; Humans; Imidazoles; Kinetics; Myocardium; Phenylephrine; Piperazines; Prazosin; Rats; Receptors, Adrenergic, alpha-1; Sarcolemma; Sodium-Hydrogen Exchangers; Tetrahydronaphthalenes | 1998 |
Molecular cloning, expression and characterization of cDNA encoding a mouse alpha1a-adrenoceptor.
Topics: Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Base Sequence; Clonidine; Cloning, Molecular; COS Cells; DNA Primers; DNA, Complementary; Female; Humans; Inositol Phosphates; Male; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Radioligand Assay; Receptors, Adrenergic, alpha-1; Sequence Homology, Amino Acid | 1998 |
Kinetics of alkylation of cloned rat alpha1-adrenoceptor subtypes by chloroethylclonidine.
Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Brain; Clonidine; Cloning, Molecular; Computer Simulation; COS Cells; Escherichia coli; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Recombinant Proteins | 1998 |
Functional effects of castration on alpha1-adrenoceptors in rat vas deferens.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Castration; Clonidine; Dioxanes; Male; Muscle Contraction; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstrictor Agents | 1998 |
Discrimination of alpha1-adrenoceptor subtypes in rat aorta and prostate.
Topics: Acetonitriles; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperazines; Prazosin; Prostate; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Vasoconstriction; Vasodilator Agents | 1998 |
Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Clonidine; Female; Kidney; Liver; Male; Mice; Mice, Knockout; Radioligand Assay; Receptors, Adrenergic, alpha-1 | 1998 |
Chloroethylclonidine is a partial alpha1-adrenoceptor agonist in aorta and caudal arteries of the Wistar Kyoto rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Vasoconstriction; Yohimbine | 1998 |
Maturation and aging-related differences in responsiveness of rat aorta and carotid arteries to alpha1-adrenoceptor stimulation.
Topics: Adrenergic alpha-Antagonists; Aging; Analysis of Variance; Animals; Aorta, Thoracic; Carotid Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Male; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstrictor Agents | 1998 |
Infarct size-reducing effect of heat stress and alpha1 adrenoceptors in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Heat Stress Disorders; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Infarction; Male; Myocardial Ischemia; Organ Culture Techniques; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reperfusion Injury | 1998 |
Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Azepines; Binding, Competitive; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Nicergoline; Prazosin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sensitivity and Specificity; Tritium | 1999 |
Altered alpha 1-adrenoceptor subtypes mediated cardiac function after treatment of propranolol to rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Heart Rate; Male; Myocardial Contraction; Phenylephrine; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Stimulation, Chemical | 1997 |
Characterization of alpha1-adrenoceptor subtypes mediating vasoconstriction in human umbilical vein.
Topics: Adrenergic Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Humans; In Vitro Techniques; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Umbilical Veins; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Functional characterization of alpha1-adrenoceptor subtypes in longitudinal and circular muscle of human vas deferens.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Alkylating Agents; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Piperazines; Prazosin; Receptors, Adrenergic; Spiperone; Vas Deferens | 1999 |
Preconditioning prevents the negative inotropic action of phenylephrine in rat isolated stunned papillary muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Cardiotonic Agents; Clonidine; Dioxanes; Female; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Muscle Contraction; Papillary Muscles; Phenylephrine; Rats; Rats, Wistar; Reperfusion Injury; Yohimbine | 1999 |
Analysis of alpha 1L-adrenoceptor pharmacology in rat small mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cresols; Imidazoles; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Norepinephrine; Piperazines; Potassium; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Tetrahydronaphthalenes | 1999 |
Characterization of alpha 1-adrenoceptors expressed in a novel vascular smooth muscle cell line cloned from p53 knockout mice, P53LMAC01 (AC01) cells.
Topics: Alkylation; Animals; Aorta; Binding Sites; Cell Line; Cells, Cultured; CHO Cells; Clone Cells; Clonidine; Cricetinae; Humans; Inositol 1,4,5-Trisphosphate; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Piperazines; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tumor Suppressor Protein p53 | 1999 |
Characterization of alpha1-adrenoceptor subtypes mediating noradrenaline-induced contraction of rat epididymal vas deferens in calcium-free medium.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Citric Acid Cycle; Clonidine; Culture Media; Epididymis; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Vas Deferens | 1999 |
Chloroethylclonidine and 2-aminoethyl methanethiosulfonate recognize two different conformations of the human alpha(2A)-adrenergic receptor.
Topics: Adrenergic alpha-Antagonists; Amino Acid Substitution; Animals; Binding Sites; CHO Cells; Clonidine; Cricetinae; Cysteine; Ethyl Methanesulfonate; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Thermodynamics; Transfection | 1999 |
Direct block of native and cloned (Kir2.1) inward rectifier K+ channels by chloroethylclonidine.
Topics: Animals; Clonidine; Kinetics; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Adrenergic, alpha; Recombinant Proteins | 1999 |
Expression and pharmacological characterization of alpha1-adrenoceptors in rat seminal vesicle.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Epinephrine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Phenoxybenzamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seminal Vesicles | 1999 |
Differential blockade of alpha,beta-methylene-ATP, noradrenaline and electrically evoked contractions of the rat vas deferens.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Clonidine; Cromakalim; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Nifedipine; Norepinephrine; Papaverine; Rats; Rats, Wistar; Vas Deferens; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 1999 |
Characterisation of alpha1B-adrenoceptors linked to inositol phosphate formation and calcium mobilisation in human astrocytoma U373 MG cells.
Topics: Adrenergic alpha-Antagonists; Astrocytoma; Calcium; Cell Membrane; Clonidine; Dihydropyridines; Dioxanes; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Thymidine; Tumor Cells, Cultured | 1999 |
Differences in the electrophysiologic response of four canine ventricular cell types to alpha 1-adrenergic agonists.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Endocardium; Heart Ventricles; In Vitro Techniques; Methoxamine; Microelectrodes; Pericardium; Phenylephrine; Prazosin; Propranolol; Purkinje Fibers | 1999 |
alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anilides; Animals; Blood Vessels; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Nasal Mucosa; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Spiperone; Vasoconstriction; Yohimbine | 2000 |
alpha(1)-adrenoceptor subtypes in rat renal resistance vessels: in vivo and in vitro studies.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Arterioles; Calcium; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Vascular Resistance | 2000 |
Methoxamine inhibits transient outward potassium current through alpha1A-adrenoceptors in rat ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Ventricles; In Vitro Techniques; Male; Membrane Potentials; Methoxamine; Patch-Clamp Techniques; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Time Factors | 2000 |
Differential response to chloroethylclonidine in blood vessels of normotensive and spontaneously hypertensive rats: role of alpha 1D- and alpha 1A-adrenoceptors in contraction.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptors, Adrenergic, alpha-1; Species Specificity | 2000 |
Ligand association with the rabbit kidney and brain Y1, Y2 and Y5-like neuropeptide Y (NPY) receptors shows large subtype-related differences in sensitivity to chaotropic and alkylating agents.
Topics: Alkylating Agents; Amiloride; Amino Acid Sequence; Animals; Brain; CHO Cells; Clonidine; Cricetinae; Cystamine; Ethylmaleimide; Gastrointestinal Hormones; GTP-Binding Protein alpha Subunits, Gs; Guinea Pigs; Humans; Hypothalamus; Kidney; Ligands; Mesylates; Molecular Sequence Data; Peptide Fragments; Peptide YY; Rabbits; Radioligand Assay; Receptors, Neuropeptide Y; Sodium Cholate; Sulfhydryl Compounds; Urea | 2000 |
Role of alpha-1 adrenoceptor subtypes mediating constriction of the rabbit ear thermoregulatory microvasculature.
Topics: Animals; Arteriovenous Anastomosis; Body Temperature Regulation; Clonidine; Dose-Response Relationship, Drug; Ear; Male; Microcirculation; Phenylephrine; Piperazines; Rabbits; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2000 |
Both alpha(1A)- and alpha(1B)-adrenergic receptor subtypes couple to the transient outward current (I(To)) in rat ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; DNA Primers; Electrophysiology; Heart; Heart Ventricles; In Vitro Techniques; Indoles; Ion Channels; Methoxamine; Myocardium; Patch-Clamp Techniques; Phenethylamines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; Tetralones | 2000 |
Smooth muscle and parasympathetic nerve terminals in the rat urinary bladder have different subtypes of alpha(1) adrenoceptors.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscle, Smooth; Parasympathetic Nervous System; Phenylephrine; Rats; Receptors, Adrenergic, alpha-1; Time Factors; Urinary Bladder | 2000 |
Role of alpha1A-adrenoceptor in the regulation of glucose uptake into white adipocyte of rats in vitro.
Topics: Adipocytes; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alkaloids; Animals; Benzophenanthridines; Biological Transport, Active; Chromones; Clonidine; Deoxyglucose; Dioxanes; Enzyme Inhibitors; Estrenes; Glucose; Glucose Transporter Type 4; Indoles; Male; Maleimides; Methoxamine; Monosaccharide Transport Proteins; Morpholines; Muscle Proteins; Phenanthridines; Phosphoinositide-3 Kinase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Sulfonamides; Tamsulosin; Type C Phospholipases | 2000 |
Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Abdominal; Aorta, Thoracic; Clonidine; Endothelin Receptor Antagonists; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; Inositol Phosphates; Male; Muscle Contraction; Norepinephrine; Peptides, Cyclic; Piperazines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Adrenergic, alpha; Receptors, Endothelin; Receptors, Thromboxane; Vasoconstrictor Agents | 2001 |
Pertussis toxin-sensitive and -insensitive mechanisms of alpha1-adrenoceptor-mediated inotropic responses in rat heart.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Drug Interactions; Male; Myocardial Contraction; Pertussis Toxin; Phenylephrine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vasoconstrictor Agents; Vasodilator Agents; Virulence Factors, Bordetella | 2001 |
Functional characterization of alpha(1)-adrenoceptor subtypes in human skeletal muscle resistance arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Arteries; Clonidine; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Muscle, Skeletal; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vasoconstriction | 2001 |
The alpha(1A)-adrenoceptor subtype mediates contraction in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Isoquinolines; Male; Naphthyridines; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Vascular Resistance; Vasoconstriction | 2001 |
Characterization of alpha1-adrenoceptor-mediated contraction in the mouse thoracic aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Buspirone; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Epinephrine; In Vitro Techniques; Male; Methoxamine; Mice; Models, Biological; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Statistics as Topic; Vasoconstriction | 2001 |
Existence of alpha(1A)- and alpha(1B)-adrenoceptor subtypes in canine mandibular alveolar arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alveolar Process; Animals; Arteries; Clonidine; Dioxanes; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mandible; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vasoconstriction; Xylazine; Yohimbine | 2001 |
Modulatory role of a constitutively active population of alpha(1D)-adrenoceptors in conductance arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Arteries; Calcium; Clonidine; Dose-Response Relationship, Drug; Female; Iliac Artery; Mesenteric Arteries; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance | 2002 |
Changes in alpha(1)-adrenergic vascular reactivity in monocrotaline-treated rats.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Mesenteric Arteries; Monocrotaline; Norepinephrine; Piperazines; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Thoracic Arteries; Vasoconstriction | 2002 |
[Alpha1-adrenoceptor subtypes in rabbit penile corpus cavernosum].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Clonidine; Male; Norepinephrine; Penile Erection; Penis; Piperazines; Protein Isoforms; Rabbits; Radioligand Assay; Receptors, Adrenergic, alpha-1 | 1998 |
Existence of functional alpha1A- and alpha1D- but no alpha1B-adrenoceptor subtypes in rat common carotid arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Carotid Arteries; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Methoxamine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2002 |
Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin.
Topics: Adrenergic alpha-Antagonists; Animals; Boron Compounds; Clonidine; COS Cells; Flow Cytometry; Fluorescent Dyes; Indoles; Ligands; Microscopy, Confocal; Prazosin; Receptors, Adrenergic, alpha-1; Subcellular Fractions; Transfection | 2002 |
Adrenergic activation of cardiac phospholipase D: role of alpha(1)-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Clonidine; Dioxanes; Male; Myocardium; Norepinephrine; Perfusion; Phospholipase D; Piperazines; Prazosin; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Signal Transduction; Stimulation, Chemical | 2002 |
Noradrenaline-induced contraction of human saphenous vein and human internal mammary artery: involvement of different alpha-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Aged; Clonidine; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha; Regression Analysis; Saphenous Vein; Yohimbine | 2002 |
Adrenaline (via alpha(1B)-adrenoceptors) and ethanol stimulate OH* radical production in isolated rat hepatocytes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Cells, Cultured; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Epinephrine; Ethanol; Hepatocytes; Hydroxyl Radical; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2002 |
Evidence for the role of alpha1D- and alpha1A-adrenoceptors in contraction of the rat mesenteric artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phenylephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1 | 2003 |
Interaction between neuropeptide Y Y1 receptors and alpha1B-adrenoceptors in the neurovascular junction of canine splenic arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Neuromuscular Junction; Neuropeptide Y; Piperazines; Protein Binding; Receptor Cross-Talk; Receptors, Adrenergic, alpha-1; Receptors, Neuropeptide Y; Splenic Artery; Vasoconstriction | 2003 |
Effects of castration and of testosterone replacement on alpha(1)-adrenoceptor subtypes in the rat vas deferens.
Topics: Animals; Castration; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Male; Muscle Contraction; Neuronal Plasticity; Norepinephrine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Testosterone; Time Factors; Vas Deferens; Yohimbine | 2003 |
Effects of castration on alpha 1-adrenoceptor subtypes in the rat aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Orchiectomy; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstrictor Agents | 2002 |
Alpha1-adrenoceptor subtypes involved in vasoconstrictor responses to exogenous and neurally released noradrenaline in rat femoral resistance arteries.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; In Vitro Techniques; Male; Muscle, Skeletal; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Evidence that alpha(1B)-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Animals; Arteries; Clonidine; Dioxins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Prazosin; Pyrimidinones; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tail | 2004 |
The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats.
Topics: Animals; Blood Glucose; Clonidine; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electric Stimulation; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Kidney Cortex; Malaysia; Male; Methoxamine; Muscle, Smooth, Vascular; Nitrendipine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Inbred SHR; Receptors, Adrenergic, alpha-1; Streptozocin; Time Factors; Vasoconstriction | 2004 |
Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.
Topics: Adrenergic alpha-1 Receptor Antagonists; Analysis of Variance; Androgens; Animals; Autoradiography; Barium Compounds; Chlorides; Clonidine; Cyproterone Acetate; Dioxanes; Gene Expression Regulation; Male; Orchiectomy; Organ Size; Phenylephrine; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; RNA, Messenger; Seminal Vesicles; Testosterone | 2004 |
Noradrenergic regulation of prolactin secretion at the level of the paraventricular nucleus of the hypothalamus: functional significance of the alpha-1b and beta-adrenergic receptor subtypes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cricetinae; Dose-Response Relationship, Drug; Isoproterenol; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenylephrine; Prolactin; Propranolol; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta | 2004 |
Submandibular gland acinar cells express multiple alpha1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Membrane; Cells, Cultured; Clonidine; Male; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; RNA, Messenger; Submandibular Gland; Tritium | 2004 |
Pharmacological characterization of alpha1-adrenoceptors in mouse isolated femoral small arteries.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Algorithms; Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Femoral Artery; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Norepinephrine; Piperazines; Prazosin; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Effects of norepinephrine on alpha-subtype receptors in the feline pulmonary vascular bed.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Angiotensin II; Animals; Cats; Clonidine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation, Preclinical; Ephedrine; Female; Injections, Intra-Arterial; Injections, Intravenous; Male; Norepinephrine; Phenylephrine; Piperazines; Pulmonary Artery; Pulmonary Circulation; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstrictor Agents | 2004 |
Postjunctional alpha1-adrenoceptors in the vasculature of the pithed mouse are of the alpha1A-subtype.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Carotid Arteries; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Male; Mice; Models, Animal; Norepinephrine; Piperazines; Receptors, Adrenergic, alpha-1; Vagotomy; Vasoconstrictor Agents | 2005 |
Fentanyl attenuates alpha1B-adrenoceptor-mediated pulmonary artery contraction.
Topics: Anesthetics, Intravenous; Animals; Clonidine; Dogs; Dose-Response Relationship, Drug; Fentanyl; Hydrogen-Ion Concentration; In Vitro Techniques; Phenylephrine; Piperazines; Prazosin; Pulmonary Artery; Receptors, Adrenergic, alpha-1; Vasoconstriction | 2005 |
Evidence for involvement of alpha1D-adrenoceptors in contraction of femoral resistance arteries using knockout mice.
Topics: Animals; Clonidine; Electric Stimulation; Femoral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptors, Adrenergic, alpha-1; Vascular Resistance; Vasoconstriction | 2005 |
Chloroethylclonidine reveals that alpha (1 A)-adrenoceptors mediate contraction in aorta of alpha (1 D)-adrenoceptor knockout mice.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dose-Response Relationship, Drug; Imines; In Vitro Techniques; Mice; Mice, Knockout; Norepinephrine; Piperazines; Piperidines; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents | 2005 |
(+)-Cyclazosin, a selective alpha1B-adrenoceptor antagonist: functional evaluation in rat and rabbit tissues.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Binding, Competitive; Clonidine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methoxamine; Molecular Structure; Muscle Contraction; Norepinephrine; Quinazolines; Quinoxalines; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vas Deferens; Vasoconstriction | 2005 |
Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes.
Topics: Acetyl-CoA C-Acyltransferase; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Calcium Channel Blockers; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Male; Muscle Contraction; Nifedipine; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P2; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spiperone; Suramin; Sympathetic Nervous System; Synaptic Transmission; Testis | 2006 |
Adrenergic control of a constitutively active acetylcholine-regulated potassium current in canine atrial cardiomyocytes.
Topics: Acetylcholine; Action Potentials; Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bee Venoms; Clonidine; Cyclic AMP-Dependent Protein Kinases; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Estrenes; Heart Atria; Imidazoles; Indoles; Isoproterenol; Isoquinolines; Maleimides; Myocytes, Cardiac; Patch-Clamp Techniques; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Potassium Channels; Prazosin; Propanolamines; Propranolol; Protein Kinase C; Pyrrolidinones; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Sulfonamides; Type C Phospholipases | 2007 |
Activation of alpha1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes.
Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Size; Clonidine; Cytochromes c; Decanoic Acids; Diazoxide; Hydroxy Acids; Male; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Reperfusion Injury; Vasodilator Agents | 2007 |
Influence of cisplatin-induced renal failure on the alpha(1)-adrenoceptor subtype causing vasoconstriction in the kidney of the rat.
Topics: Amlodipine; Animals; Cisplatin; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intraperitoneal; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Renal Circulation; Renal Insufficiency; Vasoconstriction; Vasodilator Agents | 2007 |
Alpha1A-adrenoceptors predominate in the control of blood pressure in mouse mesenteric vascular bed.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Mice; Mice, Inbred Strains; Phenylephrine; Piperazines; Receptors, Adrenergic, alpha-1; Tetrahydronaphthalenes; Thymine; Vasoconstriction | 2007 |
Expressions and mechanical functions of alpha1-adrenoceptor subtypes in hamster ureter.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; Immunohistochemistry; In Vitro Techniques; Indoles; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylephrine; Piperazines; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ureter | 2007 |
Alpha1B-adrenoceptors mediate adrenergically-induced renal vasoconstrictions in rats with renal impairment.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Diabetic Nephropathies; In Vitro Techniques; Kidney Diseases; Male; Muscle Tonus; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Renal Circulation; Sympathetic Nervous System; Vasoconstriction | 2008 |
Functional subtypes of renal alpha1-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension, Renovascular; Kidney; Male; Methoxamine; Nitrendipine; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2008 |
Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Body Weight; Clonidine; Drinking; Hydroxylamines; Kidney Cortex; Male; Norepinephrine; Phenylephrine; Piperazines; Rats; Rats, Inbred WKY; Receptors, Adrenergic, alpha-1; Renal Circulation; Sodium; Sodium, Dietary; Urine; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Inhibitory effect of fentanyl on phenylephrine-induced contraction of the rat aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Fentanyl; In Vitro Techniques; Male; Phenylephrine; Piperazines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2009 |
Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Anesthesia, Local; Anesthetics, Local; Animals; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Male; Methoxamine; Nifedipine; Nitroglycerin; Pain Measurement; Phentolamine; Phenylephrine; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1 | 2009 |
Modulation of potassium channels via the α1B-adrenergic receptor in human osteoblasts.
Topics: Adrenergic alpha-Antagonists; Cell Line; Clonidine; Humans; Male; Membrane Potentials; Norepinephrine; Osteoblasts; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Receptors, Adrenergic, alpha-1; Young Adult | 2010 |
Molecular and pharmacological characteristics of the gerbil α(1a)-adrenergic receptor.
Topics: Adrenergic alpha-1 Receptor Antagonists; Amino Acid Sequence; Animals; Arteries; Chlorocebus aethiops; Clonidine; Cloning, Molecular; Cochlea; Conserved Sequence; COS Cells; Dioxanes; Dose-Response Relationship, Drug; Gerbillinae; Humans; Mice; Molecular Sequence Data; Piperazines; Prazosin; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Sequence Analysis, Protein; Transfection; Vasoconstriction | 2012 |
Ma huang and alpha subtype adrenoceptors in the cat pulmonary vascular bed.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ephedra sinica; Female; Lung; Male; Phentolamine; Piperazines; Prazosin; Prospective Studies; Pulmonary Circulation; Receptors, Adrenergic; Vasoconstrictor Agents | 2008 |
Blockade of different subtypes of α(1)-adrenoceptors produces opposite effect on heart chronotropy in newborn rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Animals, Newborn; Clonidine; Dioxanes; Heart Rate; Piperazines; Rats; Receptors, Adrenergic, alpha-1 | 2012 |
SDF-1α and LPA modulate microglia potassium channels through rho gtpases to regulate cell morphology.
Topics: Actin Cytoskeleton; Animals; Animals, Newborn; Antigens, Differentiation; Cell Size; Cerebral Cortex; Chemokine CXCL12; Clonidine; Lysophospholipids; Mice; Microglia; Microscopy, Confocal; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Protein Transport; rac1 GTP-Binding Protein; Receptors, CXCR4; rho GTP-Binding Proteins; Signal Transduction; Transfection | 2013 |
The molecular basis of chloroethylclonidine block of inward rectifier (Kir2.1 and Kir4.1) K(+) channels.
Topics: Cell Line; Cell Membrane; Clonidine; Cytoplasm; HEK293 Cells; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Potassium; Potassium Channels, Inwardly Rectifying | 2016 |
Cystathione gamma lyase/Hydrogen Sulphide Pathway Up Regulation Enhances the Responsiveness of α1A and α1B-Adrenoreceptors in the Kidney of Rats with Left Ventricular Hypertrophy.
Topics: Adrenergic beta-Antagonists; Animals; Clonidine; Cystathionine gamma-Lyase; Hydrogen Sulfide; Hypertrophy, Left Ventricular; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Renal Circulation; Sulfurtransferases; Up-Regulation | 2016 |