chlordiazepoxide has been researched along with mrk-409 in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Atack, JR; Bormans, G; Burns, HD; Dawson, GR; de Hoon, JN; De Lepeleire, I; Hargreaves, RJ; McKernan, RM; Murphy, MG; Sanabria-Bohórquez, SM; Street, LJ; Tye, S; Van Hecken, A; Van Laere, K; Wafford, KA | 1 |
1 trial(s) available for chlordiazepoxide and mrk-409
Article | Year |
---|---|
MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans.
Topics: Adolescent; Adult; Animals; Anti-Anxiety Agents; Anxiety; Binding Sites; Brain; Chlordiazepoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GABA-A Receptor Agonists; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrocarbons, Fluorinated; Male; Mice; Middle Aged; Positron-Emission Tomography; Protein Binding; Protein Subunits; Rats; Rats, Sprague-Dawley; Saimiri; Species Specificity; Tissue Distribution; Young Adult | 2011 |