chlordiazepoxide and baclofen

chlordiazepoxide has been researched along with baclofen in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's4 (22.22)18.2507
2000's1 (5.56)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Coop, CF; McNaughton, N; Scott, DJ1
File, SE; Hitchcott, PK; Zharkovsky, A1
Bond, A; Neal, H1
Gray, JA; Henney, S; Lawson, P; Mellanby, J; Quintero, S1
Buckland, C; Gray, JA; McNaughton, N; Mellanby, J; Quintero, S1
Gray, JA; McNaughton, N; Mellanby, J; Nordeen, H; Nutt, D; Quintero, S; Thompson, MR1
Buckland, C; Gray, JA; Mellanby, J1
Akashi, A; Kawajiri, S; Kojima, H1
Emerich, DF; Stackman, RW; Taylor, LA; Walsh, TJ1
Chugh, Y; Saha, N; Sankaranaryanan, A; Sharma, PL1
Foreman, MM; Hanania, T; Malekiani, SA; Olivier, B; Paterson, NE1
Cates-Gatto, C; Finn, MG; Kaczanowska, K; Li, X; Markou, A; Risbrough, VB; Roberts, AJ1
Girish, K; Manjunatha, R; Nagraj, M; Pandit, LV; Pundarikaksha, HP; Shruthi, R; Vasundara, K; Vijendra, R; Vikram Reddy, K1
Liu, J; Wang, LN1

Reviews

2 review(s) available for chlordiazepoxide and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Baclofen for alcohol withdrawal.
    The Cochrane database of systematic reviews, 2017, 08-20, Volume: 8

    Topics: Alcohol-Induced Disorders; Baclofen; Chlordiazepoxide; Diazepam; Ethanol; GABA Agonists; Humans; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome

2017

Trials

1 trial(s) available for chlordiazepoxide and baclofen

ArticleYear
A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome.
    Biomedical journal, 2016, Volume: 39, Issue:1

    Topics: Adult; Alcohol Drinking; Baclofen; Chlordiazepoxide; Diazepam; Humans; Lorazepam; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome

2016

Other Studies

15 other study(ies) available for chlordiazepoxide and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pindolol antagonizes the effects on hippocampal rhythmical slow activity of clonidine, baclofen and 8-OH-DPAT, but not chlordiazepoxide and sodium amylobarbitone.
    Neuroscience, 1992, Volume: 46, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amobarbital; Animals; Baclofen; Chlordiazepoxide; Clonidine; Electric Stimulation; Electrodes; Electroencephalography; Flumazenil; Hippocampus; Male; Pindolol; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1992
Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:1

    Topics: Animals; Anxiety; Baclofen; Chlordiazepoxide; Diazepam; Ethanol; Flumazenil; Interpersonal Relations; Male; Nitrendipine; Rats; Substance Withdrawal Syndrome; Tremor

1992
Quantitative electrocortical changes in the rat induced by phencyclidine and other stimulants.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Dioxolanes; Electroencephalography; Isoquinolines; Isoxazoles; Male; Muscimol; Phencyclidine; Rats; Rats, Inbred Strains

1985
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing.
    Psychopharmacology, 1985, Volume: 85, Issue:2

    Topics: Amobarbital; Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Bicuculline; Carbolines; Chlordiazepoxide; Drug Interactions; Humans; Male; Muscimol; Neural Inhibition; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission

1985
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: choice behaviour in the T-maze.
    Psychopharmacology, 1985, Volume: 86, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Chlordiazepoxide; Choice Behavior; Exploratory Behavior; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
Septal driving of hippocampal theta rhythm: role of gamma-aminobutyrate-benzodiazepine receptor complex in mediating effects of anxiolytics.
    Neuroscience, 1985, Volume: 16, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Baclofen; Carbolines; Chlordiazepoxide; Diazepam; Hippocampus; Male; Meprobamate; Neural Pathways; Rats; Rats, Inbred Strains; Receptors, GABA-A; Septum Pellucidum; Theta Rhythm

1985
The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: extinction and successive discrimination.
    Psychopharmacology, 1986, Volume: 88, Issue:3

    Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Drug Interactions; Extinction, Psychological; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Time Factors

1986
[A comparison of the effects of baclofen and some other muscle relaxants on alpha-rigidity in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:3

    Topics: Animals; Baclofen; Brain Ischemia; Chlordiazepoxide; Dantrolene; Decerebrate State; Diazepam; Male; Muscle Rigidity; Rats; Rats, Inbred Strains; Tolperisone

1984
Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus.
    Brain research bulletin, 1993, Volume: 31, Issue:3-4

    Topics: Acetylcholinesterase; Animals; Baclofen; Brain; Carbolines; Chlordiazepoxide; Choline; Convulsants; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes

1993
Effects of post-training administration of (-)-baclofen and chlordiazepoxide on memory retention in ICRC Swiss mice: interactions with GABAA and GABAB receptor antagonists.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:3

    Topics: Animals; Baclofen; Chlordiazepoxide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isomerism; Male; Memory; Mice; Mice, Inbred ICR; Motor Activity; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A

1993
Pharmacological characterization of harmaline-induced tremor activity in mice.
    European journal of pharmacology, 2009, Aug-15, Volume: 616, Issue:1-3

    Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepoxide; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Harmaline; Lithium Chloride; Male; Mice; Mice, Inbred ICR; Muscimol; Neurotransmitter Agents; Piperazines; Propranolol; Raclopride; Receptors, Glutamate; Sodium Oxybate; Tremor

2009
Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice.
    Neuropharmacology, 2013, Volume: 70

    Topics: Animals; Anxiety; Baclofen; Chlordiazepoxide; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; Male; Maze Learning; Memory; Mice; Motor Activity; Norbornanes; Pentylenetetrazole; Pyrimidines; Rats; Seizures

2013