Page last updated: 2024-08-17

chloramphenicol and linezolid

chloramphenicol has been researched along with linezolid in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's28 (44.44)29.6817
2010's28 (44.44)24.3611
2020's7 (11.11)2.80

Authors

AuthorsStudies
Eldridge, GR; Garo, E; Goering, MG; Hough, GW; Hu, JF; O'Neil-Johnson, M1
Duewelhenke, N; Eysel, P; Krut, O1
Fiett, J; Gniadkowski, M; Grzesiowski, P; Hryniewicz, W; Izdebski, R; Sadowy, E1
Basilio, A; Colletti, SL; Cully, DF; Cummings, R; Dorso, K; Galgoci, A; Genilloud, O; González, I; Herath, K; Hernandez, L; Jayasuriya, H; Kodali, S; Lee, SH; Motyl, M; Painter, R; Pelaez, F; Racine, F; Salazar, O; Singh, SB; Tinney, E; Vicente, F; Wang, J; Young, K1
Cheung, A; Götz, F; Herbert, S; Meehl, M1
Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R1
Andricopulo, AD; Moda, TL; Montanari, CA1
Besier, S; Brade, V; Ludwig, A; Wichelhaus, TA; Zander, J1
Mankin, AS; Smith, LK1
Castanheira, M; Deshpande, LM; DiPersio, J; Jones, RN; Mendes, RE; Saubolle, MA1
Brickner, SJ; Duignan, J; Finegan, S; Girard, D; Huband, MD; Le, PT; Maloney, M; Schafer, J; Stone, GG; Wade, SK; Zaniewski, RP1
Lombardo, F; Obach, RS; Waters, NJ1
Bammert, GF; Banitt, LS; Barbachyn, MR; Boyle, TP; Bundy, GL; Dolak, LA; Ford, CW; Graber, DR; Hamel, JC; Han, F; Harris, DW; Hromockyj, AE; Hurd, AR; Kamilar, GM; Marotti, KR; Martin, GE; Miller, AA; Mott, JE; Munzner, JB; Palmer, JR; Ruble, JC; Seest, EP; Skepner, JE; Sweeney, MT; Zhong, WZ; Zurenko, GE1
DeVito, J; Duffy, EM; Franceschi, F; Ippolito, JA; Lawrence, L; McConnell, TS; Skripkin, E; Sutcliffe, J1
Gentry, DR; Gwynn, MN; Holmes, DJ; McCloskey, L; Rittenhouse, SF; Scangarella, N; Shawar, R1
Bohnert, JA; Fähnrich, E; Kern, WV; Schuster, S; Wehmeier, C1
Cuny, C; Kehrenberg, C; Schwarz, S; Strommenger, B; Witte, W1
Boyd, EA; Brown, D; Collins, I; Czaplewski, LG; East, SP; Fletcher, R; Gardiner, M; Haydon, DJ; Henstock, V; Ingram, P; Jones, C; Kennison, L; Noula, C; Rockley, C; Rose, V; Stokes, NR; Thomaides-Brears, HB; Ure, R; Whittaker, M1
Cui, L; Hiramatsu, K; Neoh, HM; Shoji, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z1
Hilgers, M; Locke, JB; Shaw, KJ1
Kadlec, K; Schwarz, S1
Cai, L; Gilbert, GL; Kong, F; Oftadeh, S; Xiao, M; Xu, X; Zhou, F1
Bauer, J; Harms, KS; Hölzel, CS; Schwaiger, K1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Dai, L; Huang, SY; Li, BB; Shen, JZ; Wang, MG; Wang, Y; Wu, CM; Xia, LN1
Bohnert, JA; Karamian, B; Nikaido, H1
Andersen, TM; Böttger, EC; Hobbie, SN; Long, KS; Munck, C; Schaub, MA; Vester, B1
G C, K; Hilgers, M; José Picazo, J; Locke, JB; Morales, G; Rahawi, S; Shaw, KJ; Stein, JL1
Floyd, JL; Floyd, JT; Kumar, SH; Smith, KP; Varela, MF1
Brennan, OM; Coleman, DC; Ehricht, R; Monecke, S; Schwarz, S; Shore, AC; Slickers, P1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Di Giorgio, A; Duca, M; Tran, TP; Vo, DD1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brozovic, A; Dowson, CG; Gazvoda, M; Košmrlj, J; Lloyd, A; Osmak, M; Proud, C; Roper, DI; Vajs, J1
Xu, Z1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Dahlberg, AE; Mills, JA; O'Connor, M; Thompson, J1
Hyun, S; Jeong, S; Kwon, M; Lee, J; Lee, KH; Shin, KJ; Yu, J1
Athamna, A; Athamna, M; Bast, DJ; Medlej, B; Rubinstein, E1
Cole-Sinclair, M; Davis, A; Dawson, MA; Elliott, P1
Clark, NC; Donlan, RM; Dumas, N; Jensen, B; Kohlerschmidt, D; Limberger, RJ; McDougal, LK; Musser, KA; Patel, JB; Shin, DH; Thompson, J; Weigel, LM; Zhu, W1
Arias, CA; Castañeda, E; Moreno, J; Murray, BE; Panesso, D; Quinn, JP; Reyes, J; Vallejo, M; Villegas, MV1
Bohnhorst, B; Hansen, G; Hartmann, C; Hermann, E; Peter, C; Sedlacek, L; Ure, B1
Barnhill, AE; Brewer, MT; Carlson, SA1
Ono, Y1
Bierbaum, G; Josten, M; Sahl, HG; Schreiber, F; Szekat, C1
Alcalá, L; Bouza, E; Cercenado, E; Iglesias, C; Marín, M; Martín, A; Reigadas, E1
Kannan, K; Kefi, A; Klepacki, D; Mankin, AS; Marks, J; Orelle, C; Roncase, EJ; Vázquez-Laslop, N1
Jang, GC; Jung, SC; Kang, HY; Kim, SR; Lee, HS; Lee, K; Lim, SK; Moon, DC; Nam, HM; Tamang, MD1
Afshar, D; Fallah, F; Hashemi, A; Nazari Alam, A; Pourmand, MR; Yousefi, M1
Ando-Imaoka, M; Goto, K; Goto, M; Kai, K; Mori, K1
Dennison, DD; McNeil, MB; Parish, T; Shelton, CD1
Badr, J; Elbehiry, A; Hanafy, MH; Ibrahim, MDS; Orabi, A; Osman, KM; Saad, A1
Choi, MJ; Hyun, BH; Jung, DY; Kang, HY; Lim, SK; Moon, DC; Na, SH; Oh, SJ1
Weldon, JE; Zhu, Y1
Chen, DH; Choi, J; Mankin, AS; Marks, J; Puglisi, JD; Vázquez-Laslop, N; Wang, J; Zhang, J1
Feßler, AT; Li, X; Liu, D; Liu, X; Schwarz, S; Shen, J; Shen, Z; Wang, Y; Yang, D1
Crowe-McAuliffe, C; Wilson, DN1
Anegundi, R; Shenoy, PA; Shetty, S; Vishwanath, S1
Alorabi, M; Ejaz, U; Khoso, BK; Mahmoud, SF; Sohail, M; Uddin, F; Youssef, M1

Reviews

3 review(s) available for chloramphenicol and linezolid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
    European journal of medicinal chemistry, 2020, Nov-15, Volume: 206

    Topics: Anti-Bacterial Agents; Drug Design; Methicillin-Resistant Staphylococcus aureus; Triazoles

2020
Adverse effects of antimicrobials via predictable or idiosyncratic inhibition of host mitochondrial components.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8

    Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Chloramphenicol; DNA Topoisomerases, Type I; Fluoroquinolones; Humans; Linezolid; Mitochondria; Oxazolidinones; Protein Biosynthesis; Ribosomes

2012

Other Studies

60 other study(ies) available for chloramphenicol and linezolid

ArticleYear
Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens.
    Journal of natural products, 2006, Volume: 69, Issue:4

    Topics: Annonaceae; Anti-Bacterial Agents; Gabon; Glycosides; Methicillin Resistance; Molecular Structure; Plant Leaves; Plants, Medicinal; Staphylococcus aureus

2006
Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Antimycin A; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Chloramphenicol; Clindamycin; Dose-Response Relationship, Drug; Fluoroquinolones; Glycolysis; HeLa Cells; Humans; Lactic Acid; Linezolid; Macrolides; Mitochondria; Osteoblasts; Oxazolidinones; Rotenone; Tetracyclines; Time Factors

2007
Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Bacterial Proteins; Cell Lineage; DNA Transposable Elements; Genetic Variation; Poland; Streptococcus pneumoniae; Tetracycline; Tetracycline Resistance

2007
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, May-01, Volume: 104, Issue:18

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aminophenols; Anti-Bacterial Agents; Enzyme Inhibitors; Microbial Viability; Molecular Structure; Polycyclic Compounds

2007
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Polymyxin B; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance

2007
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gene Dosage; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Point Mutation; RNA, Ribosomal, 23S; Staphylococcal Infections; Staphylococcus aureus

2008
Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Codon, Initiator; Genes, Bacterial; Methicillin Resistance; Methyltransferases; Models, Genetic; Models, Molecular; Operon; Promoter Regions, Genetic; Protein Biosynthesis; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal, 23S; Staphylococcus aureus; Transcription, Genetic

2008
First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Bacterial; Humans; Linezolid; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazolidinones; Sequence Analysis, DNA; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis

2008
In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Acetamides; Anti-Bacterial Agents; Cinnamates; Dioxoles; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hygromycin B; In Vitro Techniques; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacteria; Bacterial Infections; Bacterial Proteins; Cell Line; Cell Proliferation; Metabolic Clearance Rate; Mice; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Topoisomerase II Inhibitors

2008
R chi-01, a new family of oxazolidinones that overcome ribosome-based linezolid resistance.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Acetamides; Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Protein Biosynthesis; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 23S; Staphylococcus aureus

2008
Genetic characterization of Vga ABC proteins conferring reduced susceptibility to pleuromutilins in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12

    Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Bridged Bicyclo Compounds, Heterocyclic; Diterpenes; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pleuromutilins; Polycyclic Compounds; Sequence Analysis, DNA; Staphylococcus aureus

2008
Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Macrolides; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid

2009
Methicillin-resistant and -susceptible Staphylococcus aureus strains of clonal lineages ST398 and ST9 from swine carry the multidrug resistance gene cfr.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Plasmids; Staphylococcal Infections; Staphylococcus aureus; Swine

2009
Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.
    Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Microbial Sensitivity Tests; Staphylococcus; Structure-Activity Relationship

2009
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Chromosome Walking; DNA-Binding Proteins; Genetic Engineering; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Point Mutation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Vancomycin; Vancomycin Resistance

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins

2009
Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Acetamides; Binding Sites; Drug Resistance, Bacterial; Linezolid; Mutation; Oxazolidinones; Protein Structure, Secondary; Ribosomal Protein L3; Ribosomal Proteins; RNA, Ribosomal, 23S; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Tetrazoles

2009
Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Lincosamides; Macrolides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Plasmids; Streptogramin B; Swine; Tetracycline Resistance; Trimethoprim

2010
Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; DNA Transposable Elements; Drug Resistance, Bacterial; Erythromycin; Genotype; Humans; Macrolides; Microbial Sensitivity Tests; New South Wales; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae

2010
Resistance to linezolid in a porcine Clostridium perfringens strain carrying a mutation in the rplD gene encoding the ribosomal protein L4.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Clostridium perfringens; Drug Resistance, Bacterial; Erythromycin; Humans; Linezolid; Manure; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Ribosomal Proteins; Swine; Thiamphenicol

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Bacillus; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Feces; Lincosamides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Streptogramin B; Swine

2010
Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:9

    Topics: Anti-Bacterial Agents; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlortetracycline; Dipeptides; Doxorubicin; Doxycycline; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Minocycline; Onium Compounds; Organophosphorus Compounds; Tetracycline

2010
Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Binding Sites; Drug Resistance, Bacterial; Linezolid; Microbial Sensitivity Tests; Mutation; Mycobacterium smegmatis; Oxazolidinones; Peptidyl Transferases; Protein Binding; RNA, Ribosomal, 23S

2010
Elevated linezolid resistance in clinical cfr-positive Staphylococcus aureus isolates is associated with co-occurring mutations in ribosomal protein L3.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Acetamides; Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Bacterial; Linezolid; Methyltransferases; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Ribosomal Protein L3; Ribosomal Proteins; Staphylococcus aureus

2010
LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Amino Acid Sequence; Bacterial Proteins; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Ethidium; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Onium Compounds; Organophosphorus Compounds; Phylogeny; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Staphylococcus aureus; Trimethoprim; Vancomycin

2010
Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Drug Resistance, Multiple, Bacterial; Exotoxins; Leukocidins; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Molecular Sequence Data; Plasmids

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; DEAD-box RNA Helicases; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Models, Molecular; Molecular Sequence Data; Neoplasms; Ribonuclease III; Ribosomes; Tetracyclines

2015
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazenes

2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The protein synthesis inhibitors, oxazolidinones and chloramphenicol, cause extensive translational inaccuracy in vivo.
    Journal of molecular biology, 2002, Sep-13, Volume: 322, Issue:2

    Topics: Acetamides; Amino Acids; Aminoglycosides; Anti-Bacterial Agents; Chloramphenicol; Codon, Terminator; Drug Resistance, Bacterial; Escherichia coli; Frameshifting, Ribosomal; Genes, Reporter; Lac Operon; Linezolid; Mutation, Missense; Oxazolidinones; Protein Biosynthesis; Protein Synthesis Inhibitors

2002
An approach to enhance specificity against RNA targets using heteroconjugates of aminoglycosides and chloramphenicol (or linezolid).
    Journal of the American Chemical Society, 2004, Feb-25, Volume: 126, Issue:7

    Topics: Acetamides; Aminoglycosides; Chloramphenicol; Framycetin; Linezolid; Nucleic Acid Conformation; Oxazolidinones; RNA; Structure-Activity Relationship; Substrate Specificity

2004
In vitro post-antibiotic effect of fluoroquinolones, macrolides, beta-lactams, tetracyclines, vancomycin, clindamycin, linezolid, chloramphenicol, quinupristin/dalfopristin and rifampicin on Bacillus anthracis.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:4

    Topics: Acetamides; Anti-Bacterial Agents; Bacillus anthracis; beta-Lactams; Chloramphenicol; Clindamycin; Fluoroquinolones; Linezolid; Macrolides; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Tetracyclines; Vancomycin; Virginiamycin

2004
Linezolid-induced dyserythropoiesis: chloramphenicol toxicity revisited.
    Internal medicine journal, 2005, Volume: 35, Issue:10

    Topics: Acetamides; Aged; Anemia, Hemolytic; Bone Marrow; Chloramphenicol; Erythropoiesis; Hemoglobins; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Protein Synthesis Inhibitors; Reticulocyte Count; Reticulocytes; Sepsis; Staphylococcal Infections

2005
High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Acetamides; Aminoglycosides; Biofilms; Catheters, Indwelling; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Female; Fluoroquinolones; Humans; Linezolid; Macrolides; Microbial Sensitivity Tests; Micrococcus; Middle Aged; Morganella morganii; Oxazolidinones; Penicillins; Pseudomonas aeruginosa; Rifampin; Staphylococcus aureus; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Catheterization; Vancomycin; Vancomycin Resistance

2007
Clinical and microbiological aspects of linezolid resistance mediated by the cfr gene encoding a 23S rRNA methyltransferase.
    Journal of clinical microbiology, 2008, Volume: 46, Issue:3

    Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Colombia; Contact Tracing; Cross Infection; Drug Resistance, Bacterial; Family Characteristics; Fatal Outcome; Female; Humans; Linezolid; Methicillin Resistance; Methyltransferases; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; RNA, Ribosomal, 23S; Staphylococcal Infections; Staphylococcus aureus; Thiamphenicol

2008
Successful treatment of vancomycin-resistant Enterococcus faecium ventriculitis with combined intravenous and intraventricular chloramphenicol in a newborn.
    Journal of medical microbiology, 2010, Volume: 59, Issue:Pt 11

    Topics: Acetamides; Anti-Bacterial Agents; Cerebral Ventricles; Cerebrospinal Fluid; Chloramphenicol; Encephalitis; Enterococcus faecium; Female; Gentamicins; Gram-Positive Bacterial Infections; Head; Humans; Infant, Newborn; Infusions, Intravenous; Injections, Intraventricular; Linezolid; Lumbosacral Region; Magnetic Resonance Imaging; Oxazolidinones; Pelvis; Radiography; Treatment Outcome; Vancomycin Resistance

2010
[Antibiotics].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

    Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Chloramphenicol; Fosfomycin; Glycopeptides; Humans; Ketolides; Linezolid; Macrolides; Oxazolidinones; Peptides; Streptogramins; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination

2012
Antibiotic-induced autoactivation of IS256 in Staphylococcus aureus.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Acetamides; Anti-Bacterial Agents; Chloramphenicol; DNA Transposable Elements; Gene Expression Regulation, Bacterial; Linezolid; Mutation; Oxazolidinones; Spectinomycin; Staphylococcus aureus; Temperature

2013
Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Clindamycin; Clostridioides difficile; DNA Transposable Elements; Drug Resistance, Multiple, Bacterial; Erythromycin; Humans; Linezolid; Microbial Sensitivity Tests; Molecular Sequence Data; Ribotyping; RNA, Ribosomal, 23S; Spain

2015
Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 10-25, Volume: 113, Issue:43

    Topics: Amino Acids; Binding Sites; Chloramphenicol; Escherichia coli; Linezolid; Models, Molecular; Peptidyl Transferases; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Messenger; RNA, Transfer, Amino Acyl

2016
Detection of novel oxazolidinone and phenicol resistance gene optrA in enterococcal isolates from food animals and animal carcasses.
    Veterinary microbiology, 2017, Volume: 201

    Topics: Animals; Anti-Bacterial Agents; Bacterial Typing Techniques; Cattle; Chickens; Chloramphenicol; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus; Enterococcus faecalis; Feces; Food Microbiology; Gram-Positive Bacterial Infections; Linezolid; Multilocus Sequence Typing; Mutation; Oxazolidinones; Republic of Korea; Swine; Thiamphenicol

2017
Phenotypic and genotypic study of biofilm formation in Enterococci isolated from urinary tract infections.
    Microbial pathogenesis, 2017, Volume: 108

    Topics: Anti-Bacterial Agents; Biofilms; Chloramphenicol; Drug Resistance, Bacterial; Enterococcus; Enterococcus faecalis; Enterococcus faecium; Genes, Bacterial; Genotype; Gram-Positive Bacterial Infections; Humans; Iran; Linezolid; Microbial Sensitivity Tests; Nitrofurantoin; Phenotype; Polymerase Chain Reaction; Urinary Tract Infections; Virulence Factors

2017
Evaluation of drug-induced hematotoxicity using novel in vitro monkey CFU-GM and BFU-E colony assays.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:4

    Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chloramphenicol; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Doxorubicin; Fetal Blood; Humans; Linezolid; Macaca fascicularis; Male; Myeloid Progenitor Cells; Species Specificity

2017
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:10

    Topics: Antitubercular Agents; Base Sequence; Binding Sites; Chloramphenicol; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Protein Synthesis Inhibitors; Ribosomal Protein L3; Ribosomal Proteins; RNA, Ribosomal, 23S; Sequence Analysis, DNA; Tuberculosis, Pulmonary

2017
Poultry as a vector for emerging multidrug resistant Enterococcus spp.: First report of vancomycin (van) and the chloramphenicol-florfenicol (cat-fex-cfr) resistance genes from pigeon and duck faeces.
    Microbial pathogenesis, 2019, Volume: 128

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Chloramphenicol; Columbidae; Disease Reservoirs; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Ducks; Egypt; Enterococcus; Feces; Gene Expression Regulation, Bacterial; Humans; Linezolid; Poultry; Public Health; Thiamphenicol; Vancomycin; Vancomycin-Resistant Enterococci

2019
Detection of oxazolidinone and phenicol resistant enterococcal isolates from duck feces and carcasses.
    International journal of food microbiology, 2019, Mar-16, Volume: 293

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Chloramphenicol; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Ducks; Enterococcus faecalis; Enterococcus faecium; Erythromycin; Feces; Genes, Bacterial; Linezolid; Microbial Sensitivity Tests; Multilocus Sequence Typing; Oxazolidinones; Republic of Korea; Ribosomal Protein L3; RNA, Ribosomal, 23S; Tetracycline; Thiamphenicol

2019
Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture.
    BMC research notes, 2019, May-27, Volume: 12, Issue:1

    Topics: ADP Ribose Transferases; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bacterial Toxins; Cell Line, Tumor; Chloramphenicol; Epithelial Cells; Exotoxins; Fusidic Acid; HEK293 Cells; Humans; Immunotoxins; Inhibitory Concentration 50; Kanamycin; Linezolid; Lymphocytes; Mitochondria; Mitochondrial Proteins; Pseudomonas aeruginosa Exotoxin A; Recombinant Fusion Proteins; Streptomycin; Tetracycline; Virulence Factors

2019
Dynamics of the context-specific translation arrest by chloramphenicol and linezolid.
    Nature chemical biology, 2020, Volume: 16, Issue:3

    Topics: Amino Acids; Anti-Bacterial Agents; Binding Sites; Chloramphenicol; Escherichia coli; Fluorescence Resonance Energy Transfer; Linezolid; Peptides; Protein Binding; Protein Biosynthesis; Ribosomes; RNA, Transfer

2020
Detection of the enterococcal oxazolidinone/phenicol resistance gene optrA in Campylobacter coli.
    Veterinary microbiology, 2020, Volume: 246

    Topics: Animals; Anti-Bacterial Agents; Campylobacter coli; Chickens; China; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Ducks; Enterococcus; Genes, Bacterial; Genomic Islands; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Plasmids; Thiamphenicol

2020
Putting the antibiotics chloramphenicol and linezolid into context.
    Nature structural & molecular biology, 2022, Volume: 29, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Chloramphenicol; Drug Development; Drug Resistance, Bacterial; Humans; Linezolid; Models, Molecular; Oxazolidinones; Protein Biosynthesis; Protein Synthesis Inhibitors; Ribosomes; Structure-Activity Relationship

2022
Understanding antimicrobial susceptibility profile of Finegoldia magna: an insight to an untrodden path.
    Annals of clinical microbiology and antimicrobials, 2023, Apr-25, Volume: 22, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria, Anaerobic; Cefoxitin; Chloramphenicol; Clindamycin; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests

2023
Detection of Genes Encoding Microbial Surface Component Recognizing Adhesive Matrix Molecules in Methicillin-Resistant
    Genes, 2023, 03-24, Volume: 14, Issue:4

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefoxitin; Ceftaroline; Chloramphenicol; Ciprofloxacin; Clindamycin; Erythromycin; Gentamicins; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pyoderma; Rifampin; Staphylococcus aureus

2023