Page last updated: 2024-08-17

chloramphenicol and fleroxacin

chloramphenicol has been researched along with fleroxacin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Allam, A; Alves de Sousa, R; Artaud, I; Dumont, E; Maigre, L; Pagès, JM; Vergalli, J1
Hancock, RE; Young, M1
Amyes, SG; Lewin, CS1
Arman, D; Tural, D; Willke, A1
Arnold, K; Barros, MA; de Garis, S; Hong, CS; Kadio, A; Nelwan, R; Zavala-Trujillo, I1

Trials

1 trial(s) available for chloramphenicol and fleroxacin

ArticleYear
Randomized comparative study of fleroxacin and chloramphenicol in typhoid fever.
    The American journal of medicine, 1993, Mar-22, Volume: 94, Issue:3A

    Topics: Adolescent; Adult; Aged; Chloramphenicol; Drug Administration Schedule; Female; Fleroxacin; Humans; Male; Middle Aged; Salmonella typhi; Treatment Outcome; Typhoid Fever

1993

Other Studies

10 other study(ies) available for chloramphenicol and fleroxacin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria.
    European journal of medicinal chemistry, 2017, Feb-15, Volume: 127

    Topics: Anti-Bacterial Agents; Cell Membrane Permeability; Cephalosporins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacter aerogenes; Escherichia coli; Framycetin; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Organometallic Compounds

2017
Fluoroquinolone supersusceptibility mediated by outer membrane protein OprH overexpression in Pseudomonas aeruginosa: evidence for involvement of a nonporin pathway.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Cell Membrane; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Fleroxacin; Gene Expression; Norfloxacin; Porins; Pseudomonas aeruginosa

1992
Conditions required for the bactericidal activity of fleroxacin and pefloxacin against Escherichia coli KL 16.
    Journal of medical microbiology, 1990, Volume: 32, Issue:2

    Topics: Anti-Infective Agents; Bacterial Proteins; Chloramphenicol; Ciprofloxacin; Escherichia coli; Fleroxacin; Pefloxacin; Rifampin; RNA, Bacterial

1990
In vitro activity of eight antibiotics against Salmonella and Shigella species.
    European journal of epidemiology, 1994, Volume: 10, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Fleroxacin; Microbial Sensitivity Tests; Ofloxacin; Pefloxacin; Salmonella; Shigella; Trimethoprim, Sulfamethoxazole Drug Combination

1994