Page last updated: 2024-08-17

chloramphenicol and antipyrine

chloramphenicol has been researched along with antipyrine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199020 (45.45)18.7374
1990's3 (6.82)18.2507
2000's11 (25.00)29.6817
2010's10 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Puzyńska, L1
Fetterer, RH; Kawalek, JC1
Ansay, M; Bloden, S; Depelchin, BO1
Chenery, RJ; Jennings, P; Mason, PA; Norman, SJ; Oldham, HG; Standring, P1
Juji, T; Matsuhashi, T1
Fujii, T1
Kanazawa, T; Miyao, K; Ogo, T; Sato, M; Shiojiri, H1
Kanetaka, T; Oda, T1
Furkert, K1
Busmann, GJ1
Mehta, S1
Garg, SK; Mathur, VS; Shukla, VK1
Barto, PB; Burrows, GE; Craigmill, AL; Tyler, RD1
Mathur, VS; Mehta, S; Nain, CK; Sharma, B2
Kaur, S; Koshy, A; Kumar, B; Narang, AP; Sharma, SC1
Datta, DV; Kaur, S; Koshy, A; Kumar, B; Narang, AP; Sharma, SC1
Acharya, GP; Acharya, S; Chataut, C; Dance, DA; Davis, TM; Harris, S; Ho, M; Kafle, KE; Nosten, F; Pokhrel, B; Smith, A; Tuhladar, N; Weber, A; White, NJ1
Bajoria, R; Holt, DE1
LALLIER, R1
TERZANI, A1
CHIBU, K; ICHIMARU, M1

Reviews

4 review(s) available for chloramphenicol and antipyrine

ArticleYear
[Malnutrition and drug metabolism in man (author's transl)].
    Przeglad lekarski, 1979, Volume: 36, Issue:8

    Topics: Antipyrine; Biological Availability; Biotransformation; Child, Preschool; Chloramphenicol; Half-Life; Humans; Infant; Microsomes, Liver; Protein-Energy Malnutrition; Sulfadiazine; Tetracycline

1979
Malnutrition and drug metabolism in man.
    Nutrition reviews, 1976, Volume: 34, Issue:8

    Topics: Adult; Animals; Antipyrine; Biotransformation; Blood Proteins; Child; Chloramphenicol; Dose-Response Relationship, Drug; Half-Life; Humans; Nutrition Disorders; Protein Binding; Protein-Energy Malnutrition; Sulfadiazine; Tetracycline

1976
[Otologic agents. 13].
    Pharmazeutische Praxis, 1967, Volume: 9

    Topics: Adrenal Cortex Hormones; Aminopyrine; Anesthetics, Local; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Antipyrine; Benzocaine; Chloramphenicol; Disinfectants; Ear Diseases; Formaldehyde; Humans; Hydrocortisone; Lidocaine; Neomycin; Nitrofurazone; Prednisolone; Procaine; Tetracaine; Toluene

1967
Drug disposition in children with protein energy malnutrition.
    Journal of pediatric gastroenterology and nutrition, 1983, Volume: 2, Issue:3

    Topics: Acetaminophen; Antipyrine; Biological Availability; Biotransformation; Child; Child, Preschool; Chloramphenicol; Gentamicins; Humans; Infant; Isoniazid; Kidney; Liver; Penicillins; Pharmaceutical Preparations; Protein-Energy Malnutrition; Sulfadiazine; Tissue Distribution

1983

Trials

1 trial(s) available for chloramphenicol and antipyrine

ArticleYear
Factors affecting the pharmacokinetics of parenteral chloramphenicol in enteric fever.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Anemia; Antipyrine; Chloramphenicol; Female; Glomerular Filtration Rate; Humans; Indocyanine Green; Injections, Intramuscular; Injections, Intravenous; Iothalamic Acid; Kidney; Liver Circulation; Male; Middle Aged; Salmonella; Typhoid Fever

1997

Other Studies

39 other study(ies) available for chloramphenicol and antipyrine

ArticleYear
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of Haemonchus contortus infection on the clearance of antipyrine, sulfobromophthalein, chloramphenicol, and sulfathiazole in lambs.
    American journal of veterinary research, 1990, Volume: 51, Issue:12

    Topics: Animals; Antipyrine; Chloramphenicol; Female; Haemonchiasis; Male; Metabolic Clearance Rate; Sheep; Sheep Diseases; Sulfathiazole; Sulfathiazoles; Sulfobromophthalein

1990
Antipyrine disposition in calves. I. Effects of some drugs.
    Journal of veterinary pharmacology and therapeutics, 1987, Volume: 10, Issue:1

    Topics: Animals; Antipyrine; Cattle; Chloramphenicol; Dexamethasone; Griseofulvin; Half-Life; Kinetics; Liver; Oxytetracycline

1987
Antipyrine metabolism in cultured rat hepatocytes.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Animals; Antipyrine; Cells, Cultured; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Edaravone; Isoenzymes; Kinetics; Liver; Male; Rats; Rats, Inbred Strains

1987
Antibody production to low molecular drugs in experimental animals and in man.
    The Japanese journal of experimental medicine, 1969, Volume: 39, Issue:1

    Topics: Animals; Antibodies; Antibody Formation; Antipyrine; Blood Proteins; Chloramphenicol; Chromatography; Chromatography, Gel; Erythrocytes; Female; Freund's Adjuvant; gamma-Globulins; Guinea Pigs; Hemagglutination Tests; Humans; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Injections, Intravenous; Male; Mercaptoethanol; Molecular Weight; Passive Cutaneous Anaphylaxis; Pharmaceutical Preparations; Precipitins; Rabbits; Serum Albumin

1969
Effects of vitamin E on toxicoderma associated with liver damage. Case report.
    The Keio journal of medicine, 1972, Volume: 21, Issue:2

    Topics: Adult; Alkanesulfonates; Antipyrine; Aspirin; Chloramphenicol; Female; Humans; Liver Diseases; Skin Diseases; Vitamin E

1972
Effect of consecutive dosing of thiamphenicol on its own serm concentration and liver drug metabolizing enzyme activities.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:3

    Topics: Animals; Antipyrine; Chloramphenicol; Cytochrome P-450 Enzyme System; Formaldehyde; Hexobarbital; Hydroxylation; Immune Sera; Liver; Male; Microsomes, Liver; Phenethylamines; Rabbits

1972
Toxic liver injuries.
    Acta pathologica japonica, 1973, Volume: 23, Issue:3

    Topics: Anti-Bacterial Agents; Antipyrine; Antitubercular Agents; Biopsy; Carbon Tetrachloride Poisoning; Cephalothin; Chemical and Drug Induced Liver Injury; Chloramphenicol; Fatty Liver; Humans; Liver; Microscopy, Electron; Occupational Medicine; Povidone; Suicide; Trichloroethylene

1973
[Local therapy of diseases of the middle ear].
    Therapie der Gegenwart, 1967, Volume: 106, Issue:10

    Topics: Antipyrine; Chloramphenicol; Dexamethasone; Humans; Otitis Media; Pantothenic Acid; Tetracaine

1967
Influence of prednisolone on antipyrine and chloramphenicol disposition in rabbits.
    Pharmacology, 1984, Volume: 29, Issue:2

    Topics: Animals; Antipyrine; Chloramphenicol; Half-Life; Kinetics; Male; Prednisolone; Rabbits

1984
Chloramphenicol and the neonatal calf.
    American journal of veterinary research, 1984, Volume: 45, Issue:8

    Topics: Age Factors; Animals; Animals, Newborn; Antipyrine; Biological Assay; Cattle; Chloramphenicol; Pharmaceutical Vehicles; Propylene Glycol; Propylene Glycols

1984
Drug metabolism in malnourished children.
    Progress in clinical and biological research, 1981, Volume: 77

    Topics: Acetaminophen; Antipyrine; Child, Preschool; Chloramphenicol; Half-Life; Humans; Inactivation, Metabolic; Infant; Kinetics; Protein-Energy Malnutrition; Sulfadiazine

1981
In vivo and in vitro drug metabolism in patients with leprosy.
    Leprosy in India, 1982, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aminopyrine N-Demethylase; Antipyrine; Bilirubin; Biopsy, Needle; Chloramphenicol; Female; Glucuronosyltransferase; Humans; Leprosy; Liver; Male; Middle Aged

1982
Disposition of four drugs in malnourished children.
    Drug-nutrient interactions, 1982, Volume: 1, Issue:3

    Topics: Acetaminophen; Antipyrine; Child, Preschool; Chloramphenicol; Female; Half-Life; Humans; Infant; Kinetics; Male; Protein-Energy Malnutrition; Sulfadiazine

1982
Drug metabolism in leprosy.
    The Indian journal of medical research, 1980, Volume: 71

    Topics: Adolescent; Adult; Antipyrine; Child; Chloramphenicol; Female; Humans; Leprosy; Liver; Male; Middle Aged

1980
The role of nitro-reduction and nitric oxide in the toxicity of chloramphenicol.
    Human & experimental toxicology, 1999, Volume: 18, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Antipyrine; Blood Vessels; Chloramphenicol; Drug Interactions; Female; Humans; In Vitro Techniques; Infant, Newborn; Liver; Nitric Oxide; Oxidation-Reduction; Perfusion; Placental Circulation; Pregnancy

1999
[Effects of chloramphenicol on the development of the sea urchin egg].
    Journal of embryology and experimental morphology, 1962, Volume: 10

    Topics: Animals; Antipsychotic Agents; Antipyrine; Chloramphenicol; Chlorides; Lithium; Ovum; Sea Urchins; Zinc

1962
[DAMAGE FROM THERAPY].
    La Clinica terapeutica, 1963, Oct-15, Volume: 27

    Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompatibility; Chemical and Drug Induced Liver Injury; Chloramphenicol; Drug Eruptions; Drug Hypersensitivity; Drug Therapy; Hepatitis; Neurologic Manifestations; Penicillins; Phenylbutazone; Radiation Injuries; Salicylates; Shock; Streptomycin; Sulfanilamide; Sulfanilamides; Sulfonamides; Testosterone; Thiamine; Toxicology; Vaccines

1963
[CASE OF AGRANULOCYTOSIS SHOWING A LEUKEMOID REACTION DURING THE RECOVERY PHASE].
    Naika. Internal medicine, 1964, Volume: 14

    Topics: Adrenal Cortex Hormones; Agranulocytosis; Antipyrine; Blood; Bone Marrow Examination; Chloramphenicol; Drug Hypersensitivity; Erythromycin; Laryngitis; Leukemoid Reaction; Pathology; Physiology; Toxicology

1964