Page last updated: 2024-08-17

chloramphenicol and allopurinol

chloramphenicol has been researched along with allopurinol in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's2 (8.00)18.2507
2000's11 (44.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Christensen, LK; Hansen, JM1
Sellers, E; Weser, JK1
Feller, DR; Gillette, JR; Morita, M1
Fabre, J; Herrera, A; Perrin, L; Petitpierre, B; Rudhardt, M1
Fabre, J; Perrin, L; Petitpierre, B; Rudhardt, M1
Fraunfelder, FT; Meyer, SM1
Liu, X; Matsuhashi, T; Nishizawa, Y; Usukura, J; Wakabayashi, T; Wozniak, M1
Adachi, K; Antosiewicz, J; Karbowsky, M; Matsuhashi, T; Wakabayashi, T; Wozniak, M1
BETHELL, FH; SWANSON, AL; SWENDSEID, ME1

Reviews

4 review(s) available for chloramphenicol and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
    Drugs, 1977, Volume: 13, Issue:1

    Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide

1977
Drug interactions with coumarin anticoagulants. 2.
    The New England journal of medicine, 1971, Sep-02, Volume: 285, Issue:10

    Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide

1971
Ocular toxicology update.
    Australian journal of ophthalmology, 1984, Volume: 12, Issue:4

    Topics: Adult; Aged; Allopurinol; Carbonic Anhydrase Inhibitors; Chloramphenicol; Eye Diseases; Humans; Ophthalmic Solutions; Phenylephrine; Timolol

1984

Other Studies

21 other study(ies) available for chloramphenicol and allopurinol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Reduction of niridazole by rat liver santhine oxidase.
    Biochemical pharmacology, 1971, Volume: 20, Issue:1

    Topics: Adenine; Aerobiosis; Allopurinol; Anaerobiosis; Animals; Anthelmintics; Azaguanine; Chemical Precipitation; Chloramphenicol; Furazolidone; Hydrogen-Ion Concentration; Hypoxanthines; Imidazoles; Ketones; Kinetics; Liver; Male; Milk; NAD; NADP; Nitro Compounds; Nitrofurazone; Nitrophenols; Quaternary Ammonium Compounds; Rats; Sulfates; Thiazoles; Xanthine Oxidase

1971
Behaviour of chlorpropamide in renal insufficiency and under the effect of associated drug therapy.
    International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:2

    Topics: Acenocoumarol; Allopurinol; Chloramphenicol; Chlorpropamide; Clofibrate; Glomerular Filtration Rate; Glomerulonephritis; Half-Life; Humans; Kidney; Kidney Diseases; Probenecid; Pyelonephritis

1972
[Behavior of chlorpropamide in nephropathies in the presence of associated drugs].
    Helvetica medica acta, 1972, Volume: 36, Issue:2

    Topics: Allopurinol; Chloramphenicol; Chlorpropamide; Chromium Isotopes; Humans; Kidney Diseases; Probenecid

1972
Mechanism of the formation of megamitochondria in the mouse liver induced by chloramphenicol.
    Toxicology letters, 1996, Volume: 86, Issue:1

    Topics: Allopurinol; Animals; Body Weight; Chloramphenicol; Enzyme Inhibitors; Lipid Peroxidation; Liver; Male; Mice; Microscopy, Electron; Mitochondria, Liver; Mitochondrial Swelling; Organ Size; Piperidines; Protein Synthesis Inhibitors; Purine Nucleotides

1996
Suppression of the formation of megamitochondria by scavengers for free radicals.
    Molecular aspects of medicine, 1997, Volume: 18 Suppl

    Topics: Allopurinol; Animals; Body Weight; Chloramphenicol; Coenzymes; Cyclic N-Oxides; Depression, Chemical; Enzyme Inhibitors; Ethanol; Free Radical Scavengers; Hydrazines; Lipid Peroxidation; Male; Malondialdehyde; Membrane Fusion; Mitochondria, Liver; Purines; Rats; Rats, Wistar; Spin Labels; Ubiquinone; Vitamin E; Xanthine Oxidase

1997
Effect of chloramphenicol administration on rat liver xanthine oxidase.
    The Journal of biological chemistry, 1953, Volume: 201, Issue:2

    Topics: Animals; Chloramphenicol; Liver; Oxidoreductases; Rats; Xanthine Oxidase

1953