Compounds > chlorambucil

chlorambucil and tyrosine

chlorambucil has been researched along with tyrosine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Gupta, A; Leblanc, V1
Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S2
Järvinen, J; Kärkkäinen, J; Leppänen, J; Pocasap, P; Rautio, J; Timonen, J; Weerapreeyakul, N1

Other Studies

4 other study(ies) available for chlorambucil and tyrosine

ArticleYear
Synthesis of D- and L-tyrosine-chlorambucil analogs active against breast cancer cell lines.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chlorambucil; Female; Humans; Receptor, ErbB-2; Stereoisomerism; Structure-Activity Relationship; Tyrosine

2010
SAR study of tyrosine-chlorambucil hybrid regioisomers; synthesis and biological evaluation against breast cancer cell lines.
    Amino acids, 2012, Volume: 43, Issue:2

    Topics: Antineoplastic Agents; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorambucil; Computer Simulation; Estrogen Receptor alpha; Female; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Models, Molecular; Stereoisomerism; Structure-Activity Relationship; Tyrosine

2012
Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.
    Steroids, 2012, Volume: 77, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorambucil; Drug Design; Estrogen Receptor alpha; Female; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Ovarian Neoplasms; Tyrosine; Uterine Neoplasms

2012
Tyrosine-Chlorambucil Conjugates Facilitate Cellular Uptake through L-Type Amino Acid Transporter 1 (LAT1) in Human Breast Cancer Cell Line MCF-7.
    International journal of molecular sciences, 2020, Mar-20, Volume: 21, Issue:6

    Topics: Breast Neoplasms; Cell Proliferation; Chlorambucil; Endocytosis; Female; Humans; Large Neutral Amino Acid-Transporter 1; MCF-7 Cells; Protein Binding; Time Factors; Tyrosine

2020