chlorambucil and pr-104a

chlorambucil has been researched along with pr-104a in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brown, JM; Dorie, MJ; Ferry, DM; Guise, CP; Patterson, AV; Pullen, SM; Singleton, RS; Wilson, WR	1
Atwell, GJ; Brown, JM; Chernikova, SB; Gu, Y; Patterson, AV; Thompson, LH; Wilson, WR	1

Other Studies

2 other study(ies) available for chlorambucil and pr-104a

Article	Year
DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity. Cancer research, 2009, May-01, Volume: 69, Issue:9 Topics: Animals; Cell Death; Cell Hypoxia; Cell Line, Tumor; Chlorambucil; Chromatography, Liquid; DNA Damage; DNA, Neoplasm; Female; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Nitrogen Mustard Compounds; Prodrugs; Tandem Mass Spectrometry; Xenograft Model Antitumor Assays	2009
Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A. Molecular cancer therapeutics, 2009, Volume: 8, Issue:6 Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorambucil; CHO Cells; Chromatography, Liquid; Cricetinae; Cricetulus; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endonucleases; Humans; Inhibitory Concentration 50; Molecular Structure; Mutation; NADPH-Ferrihemoprotein Reductase; Nitrogen Mustard Compounds; Rad51 Recombinase; Tandem Mass Spectrometry	2009

Article

Year

DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.

Cancer research, 2009, May-01, Volume: 69, Issue:9

Topics: Animals; Cell Death; Cell Hypoxia; Cell Line, Tumor; Chlorambucil; Chromatography, Liquid; DNA Damage; DNA, Neoplasm; Female; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Nitrogen Mustard Compounds; Prodrugs; Tandem Mass Spectrometry; Xenograft Model Antitumor Assays

2009

Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A.

Molecular cancer therapeutics, 2009, Volume: 8, Issue:6

Topics: Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chlorambucil; CHO Cells; Chromatography, Liquid; Cricetinae; Cricetulus; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endonucleases; Humans; Inhibitory Concentration 50; Molecular Structure; Mutation; NADPH-Ferrihemoprotein Reductase; Nitrogen Mustard Compounds; Rad51 Recombinase; Tandem Mass Spectrometry

2009