chlorambucil and pentostatin

chlorambucil has been researched along with pentostatin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's4 (17.39)18.2507
2000's12 (52.17)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Weiss, RB1
Phyliky, RL; Tefferi, A1
Cheson, BD1
Logan, RA; Smith, NP1
Debusscher, L; Stryckmans, P1
Begleiter, A; Israels, LG; Johnston, JB; Shore, T; Verburg, L; Williams, M1
Bosanquet, AG; Bosanquet, MI1
Byrd, JC; Flinn, IW; Goodrich, A; Grever, MR; Lucas, MA; Park, K; Shinn, C; Waselenko, JK; Willis, CR1
Beer, M; Byrd, JC; Grever, MR; Lucas, MA; Waselenko, JK1
Cabanillas, F; Dang, N; Drapkin, R; Foss, F; O'Brien, S; Vose, JM1
Weiss, MA1
Owen, RG1
Cassileth, PA; Kay, NE; Knospe, W; Lee, S; Oken, MM1
Byrd, JC; Diehl, LF; Flinn, IW; Goodrich, A; Grever, MR; Lucas, M; Park, K; Reese, A; Waselenko, JK; Willis, CR1
Bohlius, J; Greil, R; Pall, G; Richards, S; Schwarzer, G; Steurer, M1
Barry, WT; Bond, KM; Chen, Y; Decastro, CM; Diehl, LF; Friedman, DR; Gockerman, JP; Goodman, BK; Jiang, N; Moore, JO; Nevins, JR; Potti, A; Volkheimer, AD; Weinberg, JB1
Foltynski, P; Ladyzynski, P; Molik, M1
Banerji, V; Bouchard, ED; Gibson, SB; Johnston, JB; Katyal, S; Kost, SE; LaBossière, É; Liang, WS; Queau, ML; Ye, X1

Reviews

10 review(s) available for chlorambucil and pentostatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hypersensitivity reactions.
    Seminars in oncology, 1992, Volume: 19, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide

1992
A clinical update on chronic lymphocytic leukemia. II. Critical analysis of current chemotherapeutic modalities.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Chlorambucil; Deoxyadenosines; Dose-Response Relationship, Drug; Histocompatibility Testing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Prognosis; Survival Rate; Vidarabine

1992
Chronic lymphocytic leukemia and hairy-cell leukemia.
    Current opinion in oncology, 1991, Volume: 3, Issue:1

    Topics: Adult; Antineoplastic Agents; B-Lymphocytes; Chlorambucil; Humans; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasm Staging; Palliative Care; Pentostatin; Prognosis; Splenectomy

1991
Perspectives in the treatment of hairy cell leukemia.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:8

    Topics: Adult; Chlorambucil; Coformycin; Humans; Interferon Type I; Leukemia, Hairy Cell; Male; Middle Aged; Pentostatin; Splenectomy

1987
Pentostatin (Nipent) and chlorambucil with granulocyte-macrophage colony-stimulating factor support for patients with previously untreated, treated, and fludarabine-refractory B-cell chronic lymphocytic leukemia.
    Seminars in oncology, 2000, Volume: 27, Issue:2 Suppl 5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials, Phase II as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leukemia, B-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Remission Induction; Vidarabine

2000
Novel treatment strategies in chronic lymphocytic leukemia.
    Current oncology reports, 2001, Volume: 3, Issue:3

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cladribine; Cyclophosphamide; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Pentostatin; Randomized Controlled Trials as Topic; Sex Factors; Vidarabine

2001
Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:6

    Topics: Alkylating Agents; Antimetabolites; Chlorambucil; Cladribine; Clinical Trials as Topic; Drug Resistance; Drug Therapy, Combination; Guidelines as Topic; Humans; Middle Aged; Pentostatin; Plasmapheresis; Purine Nucleosides; Quality of Life; Vidarabine; Waldenstrom Macroglobulinemia

2001
Purine antagonists for chronic lymphocytic leukaemia.
    The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3

    Topics: Antineoplastic Agents; Chlorambucil; Cladribine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Randomized Controlled Trials as Topic; Vidarabine

2006
A network meta-analysis of progression free survival and overall survival in first-line treatment of chronic lymphocytic leukemia.
    Cancer treatment reviews, 2015, Volume: 41, Issue:2

    Topics: Age Factors; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Bendamustine Hydrochloride; Chlorambucil; Cyclophosphamide; Disease-Free Survival; Humans; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Markov Chains; Nitrogen Mustard Compounds; Pentostatin; Physical Fitness; Proportional Hazards Models; Randomized Controlled Trials as Topic; Rituximab; Vidarabine

2015

Trials

2 trial(s) available for chlorambucil and pentostatin

ArticleYear
Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Prednisone

2004
A phase I/II study examining pentostatin, chlorambucil, and theophylline in patients with relapsed chronic lymphocytic leukemia and non-Hodgkin's lymphoma.
    Annals of hematology, 2006, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Maximum Tolerated Dose; Middle Aged; Pentostatin; Recurrence; Remission Induction; Survival Rate; Theophylline

2006

Other Studies

11 other study(ies) available for chlorambucil and pentostatin

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Cutaneous presentation of prolymphocytic leukaemia.
    The British journal of dermatology, 1988, Volume: 118, Issue:4

    Topics: Chlorambucil; Coformycin; Humans; Leukemia, Lymphoid; Leukocyte Count; Male; Middle Aged; Pentostatin; Prednisolone; Skin; Skin Neoplasms

1988
Combination therapy with nucleoside analogs and alkylating agents.
    Leukemia, 1994, Volume: 8 Suppl 1

    Topics: Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cells, Cultured; Chlorambucil; Cyclophosphamide; Deoxyadenosines; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin

1994
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Cladribine; Comorbidity; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Methylprednisolone; Middle Aged; Neoplastic Stem Cells; Palliative Care; Pentostatin; Prednisolone; Prognosis; Staining and Labeling; Tumor Cells, Cultured; Vidarabine; Vincristine

2000
Theophylline, pentostatin (Nipent), and chlorambucil: a dose-escalation study targeting intrinsic biologic resistance mechanisms in patients with relapsed lymphoproliferative disorders.
    Seminars in oncology, 2000, Volume: 27, Issue:2 Suppl 5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cause of Death; Chlorambucil; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Progression; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Immunosuppressive Agents; Leukemia; Lymphoma; Neoplasm Recurrence, Local; Pentostatin; Phosphodiesterase Inhibitors; Theophylline

2000
Infectious complications of pentostatin therapy.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:6 Suppl 2

    Topics: Acyclovir; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chlorambucil; Encephalitis, Varicella Zoster; Herpes Zoster; Humans; Interferons; Lymphoma; Pentostatin; Pneumocystis Infections; Rituximab; Sulfamethoxazole; Trimethoprim; Valacyclovir; Valine

2000
Fludarabine: new indication. First-line treatment of CLL: unconvincing evidence.
    Prescrire international, 2005, Volume: 14, Issue:75

    Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents, Alkylating; Chlorambucil; Clinical Trials as Topic; Drug Approval; Drug Therapy, Combination; France; Humans; Injections, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Pentostatin; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Treatment Outcome; Vidarabine

2005
A genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Nov-15, Volume: 15, Issue:22

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genomics; Humans; Immunotherapy; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Pentostatin; Pharmacogenetics; Prognosis; Risk; Rituximab

2009
Cross-resistance and synergy with bendamustine in chronic lymphocytic leukemia.
    Leukemia research, 2016, Volume: 50

    Topics: Adenosine Deaminase Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bendamustine Hydrochloride; Chlorambucil; Deoxyadenosines; DNA Breaks, Double-Stranded; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Tumor Cells, Cultured

2016