chlorambucil has been researched along with nutlin-3a in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbarotto, E; Celeghini, C; Corallini, F; Fadda, R; Grill, V; Mischiati, C; Rimondi, E; Vaccarezza, M | 1 |
| di Iasio, MG; Melloni, E; Secchiero, P; Tiribelli, M; Voltan, R; Zauli, G | 1 |
2 other study(ies) available for chlorambucil and nutlin-3a
| Article | Year |
|---|---|
Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; B-Lymphocytes; Blast Crisis; Cell Cycle; Cell Line, Tumor; Chlorambucil; Humans; Imidazoles; Leukemia, Lymphocytic, Chronic, B-Cell; Piperazines; Proto-Oncogene Proteins c-mdm2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Up-Regulation; Vidarabine | 2008 |
The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; B-Lymphocytes; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Chlorambucil; Chromosomal Proteins, Non-Histone; Down-Regulation; Female; Humans; Imidazoles; Immunoenzyme Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Oncogene Proteins; Piperazines; Poly-ADP-Ribose Binding Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stereoisomerism; Tumor Suppressor Protein p53 | 2010 |