chlorambucil and metallothionein

chlorambucil has been researched along with metallothionein in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, A; Lazo, JS1
Bellet, AJ; Favier, D; Holmes, RS; Hurst, T; Kable, EP; Khoo, SK; Lean, J; Parsons, PG1
Endresen, L; Rugstad, HE1
Rugstad, HE1
Endresen, L1
Bakka, A; Endresen, L; Rugstad, HE1
Fabris, D; Fenselau, C; Han, MS; Jiang, L; Tabb, JR; Wu, Z; Zaia, J1
Fabris, D; Fenselau, C; Karpel, RL; Wei, D; Zaia, J1
Fenselau, C; Szilágyi, Z1

Reviews

1 review(s) available for chlorambucil and metallothionein

ArticleYear
Metallothionein expression and transient resistance to electrophilic antineoplastic drugs.
    Seminars in cancer biology, 1991, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents; Chlorambucil; Cisplatin; Cricetinae; Doxorubicin; Drug Resistance; Humans; Melphalan; Metallothionein; Mitomycin; Prednimustine

1991

Other Studies

8 other study(ies) available for chlorambucil and metallothionein

ArticleYear
Relationships between resistance to cross-linking agents and glutathione metabolism, aldehyde dehydrogenase isozymes and adenovirus replication in human tumour cell lines.
    Biochemical pharmacology, 1990, Dec-15, Volume: 40, Issue:12

    Topics: Adenoviruses, Human; Aldehyde Dehydrogenase; Cadmium; Cadmium Chloride; Chlorambucil; Cisplatin; Cross-Linking Reagents; Cyclophosphamide; DNA Damage; Drug Resistance; Glutathione; Humans; Isoenzymes; Melphalan; Metallothionein; Tumor Cells, Cultured; Virus Replication

1990
Protective function of metallothionein against certain anticancer agents.
    Experientia. Supplementum, 1987, Volume: 52

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Chlorambucil; Cisplatin; Colony-Forming Units Assay; Drug Resistance; Humans; Metallothionein; Mice; Mice, Nude; Neoplasms, Experimental; Prednimustine; Prednisolone

1987
Metallothionein--a unique protein with multiple detoxifying properties?
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1984, Volume: 16 Suppl 2

    Topics: Animals; Cadmium Poisoning; Cells, Cultured; Chlorambucil; Cisplatin; Drug Resistance; Gold; Humans; Inactivation, Metabolic; Metabolic Clearance Rate; Metallothionein; Mice; Radiation-Protective Agents

1984
Comparison of the cytotoxic effect of prednimustine in cultured cells with high or low levels of metallothionein.
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Chlorambucil; Colony-Forming Units Assay; Cytosol; Humans; Hydrolysis; Metallothionein; Mice; Prednimustine; Prednisolone; Protein Binding

1984
Increased resistance to chlorambucil in cultured cells with a high concentration of cytoplasmic metallothionein.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Animals; Cadmium; Cell Line; Chlorambucil; Chromatography, Gel; Copper; Cytoplasm; Drug Resistance; Fibroblasts; Humans; Metalloproteins; Metallothionein; Mice; Zinc

1983
A binding site for chlorambucil on metallothionein.
    Biochemistry, 1996, Mar-05, Volume: 35, Issue:9

    Topics: Amino Acid Sequence; Animals; Binding Sites; Chlorambucil; Chromatography, High Pressure Liquid; Computer Simulation; Liver; Mass Spectrometry; Metallothionein; Molecular Conformation; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Rabbits; Thermodynamics

1996
Monitoring metal ion flux in reactions of metallothionein and drug-modified metallothionein by electrospray mass spectrometry.
    Protein science : a publication of the Protein Society, 1998, Volume: 7, Issue:11

    Topics: Alkylation; Animals; Bacteriophage T4; Carbonic Anhydrases; Chlorambucil; DNA-Binding Proteins; Edetic Acid; Insulin; Kinetics; Liver; Mass Spectrometry; Metallothionein; Metals; Rabbits; Viral Proteins; Zinc

1998
Molecular dynamics simulation of metallothionein-drug complexes.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:2

    Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Chlorambucil; Computer Simulation; Crystallography, X-Ray; Cysteine; Mechlorethamine; Melphalan; Metallothionein; Models, Structural; Nitrogen Mustard Compounds; Protein Binding; Zinc

2000