chlorambucil and epirubicin

chlorambucil has been researched along with epirubicin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's6 (35.29)18.2507
2000's6 (35.29)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Porzsolt, F1
Buchelt, L; Heissmeyer, HH; Hiemeyer, V; Krause, HH; Kreuser, ED; Mende, S; Meuret, G; Porzsolt, F; Redenbacher, M; Strigl, P1
Grönroos, M; Kangas, L; Mäenpää, J1
Gabryś, K; Kotlarek-Haus, S; Potoczek, S1
Catsoulakos, P; Karakiulakis, G; Pispirigos, K1
Karakiulakis, G; Paradelis, AG; Pispirigos, K1
Bosanquet, AG; Bosanquet, MI1
Davey, M; Davey, R; Locke, V1
Bergmann, M; Busch, R; Emmerich, B; Franke, A; Hallek, M; Hiddemann, W; Hopfinger, G; Pasold, R; Schlag, R; Schmitt, B; Wendtner, CM1
Baldini, L; Brugiatelli, M; Cavanna, L; Colombi, M; Federico, M; Gobbi, P; Goldaniga, M; Liberati, M; Lombardo, M; Luminari, S; Merli, F; Morabito, F; Sacchi, S; Silingardi, V; Stelitano, C1
Daw, S; Hayward, J; Hewitt, M; Kirkwood, A; McCarthy, K; Morland, B; Shankar, A1

Reviews

3 review(s) available for chlorambucil and epirubicin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Chemotherapeutic options in chronic lymphocytic leukemia: a meta-analysis of the randomized trials. CLL Trialists' Collaborative Group.
    Journal of the National Cancer Institute, 1999, May-19, Volume: 91, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Prednisone; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Vincristine

1999
Fludarabine combination therapy for the treatment of chronic lymphocytic leukemia.
    Clinical lymphoma, 2002, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Alemtuzumab; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Chlorambucil; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Epirubicin; Female; Forecasting; Granulocyte Colony-Stimulating Factor; Humans; Immunotherapy; Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Mitoxantrone; Prednisone; Randomized Controlled Trials as Topic; Remission Induction; Rituximab; Treatment Outcome; Vidarabine; Vincristine

2002

Trials

3 trial(s) available for chlorambucil and epirubicin

ArticleYear
[Therapy of metastatic breast cancer at the Ulm Tumor Center in 1980 and 1990].
    Onkologie, 1990, Volume: 13, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Survival Rate; Tumor Stem Cell Assay

1990
High-intensity therapy versus low-intensity therapy in advanced breast cancer patients.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Prognosis; Random Allocation; Remission Induction; Risk Factors; Survival Rate; Tamoxifen

1990
Treatment of indolent B-Cell nonfollicular lymphomas: final results of the LL01 randomized trial of the Gruppo Italiano per lo Studio dei Linfomi.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-15, Volume: 21, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Disease-Free Survival; Drug Administration Schedule; Epirubicin; Female; Humans; Interferon alpha-2; Interferon-alpha; Lymphoma, B-Cell; Lymphoma, Follicular; Male; Middle Aged; Prednisone; Recombinant Proteins; Survival Analysis; Treatment Outcome

2003

Other Studies

11 other study(ies) available for chlorambucil and epirubicin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Response of ovarian cancer to combined cytotoxic agents in the subrenal capsule assay: Part I.
    Obstetrics and gynecology, 1985, Volume: 66, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Altretamine; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; Cystadenocarcinoma; Doxorubicin; Epirubicin; Etoposide; Female; Humans; Methotrexate; Mice; Middle Aged; Mitomycins; Naphthacenes; Neoplasm Transplantation; Ovarian Neoplasms; Tegafur; Tumor Stem Cell Assay; Vincristine

1985
[Evaluation of early treatment results in Hodgkin's disease during the cytostatic protocol containing methotrexate].
    Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Epirubicin; Female; Hodgkin Disease; Humans; Lomustine; Male; Mechlorethamine; Methotrexate; Middle Aged; Prednisone; Procarbazine; Treatment Outcome; Vincristine

1995
Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Azasteroids; Blood Glucose; Chemical and Drug Induced Liver Injury; Chlorambucil; Cholesterol; Cisplatin; Epirubicin; gamma-Glutamyltransferase; Kidney; Kidney Diseases; Liver Diseases; Male; Methotrexate; Nitrogen; Nitrogen Mustard Compounds; Potassium; Rats; Rats, Wistar; Sodium; Weight Loss

1993
Evaluation of cardiac subacute toxicity of epirubicin, chlorambucil, cisplatin, methotrexate and a homo-aza-steroid ester with antitumor activity in rats using serum biochemical parameters.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Aspartate Aminotransferases; Body Weight; Chlorambucil; Cisplatin; Creatine Kinase; Epirubicin; Heart Diseases; Isoenzymes; L-Lactate Dehydrogenase; Methotrexate; Rats

1997
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia.
    Leukemia, 2000, Volume: 14, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Cladribine; Comorbidity; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Epirubicin; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Methylprednisolone; Middle Aged; Neoplastic Stem Cells; Palliative Care; Pentostatin; Prednisolone; Prognosis; Staining and Labeling; Tumor Cells, Cultured; Vidarabine; Vincristine

2000
Paclitaxel sensitization of multidrug-resistant cells to chemotherapy is independent of the cell cycle.
    Cytometry, 2001, Mar-01, Volume: 43, Issue:3

    Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carcinoma, Small Cell; Cell Cycle; Cell Survival; Chlorambucil; Cisplatin; Daunorubicin; Drug Resistance, Multiple; Epirubicin; Genistein; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2001
Treatment outcome in children and adolescents with relapsed Hodgkin lymphoma--results of the UK HD3 relapse treatment strategy.
    British journal of haematology, 2014, Volume: 165, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Child; Chlorambucil; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Dexamethasone; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Ifosfamide; Kaplan-Meier Estimate; Melphalan; Multicenter Studies as Topic; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vinblastine; Vincristine

2014