chlorambucil and dacarbazine

chlorambucil has been researched along with dacarbazine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19908 (29.63)18.7374
1990's4 (14.81)18.2507
2000's6 (22.22)29.6817
2010's9 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Casey, AE; Griswold, DP; Prejean, JD; Weisburger, EK; Weisburger, JH; Wood, HB1
Murphy, GP1
Bramwell, VH; Pinedo, HM; Rosenberg, SA; Voûte, PA1
De Weger, RA; Den Otter, W; Dullens, HF; Vennegoor, C; Woutersen, F; Woutersen, RA1
Morley, AA; Seshadri, RS; Trainor, KJ1
Bodurtha, A; Ghose, T; Guclu, A; MacDonald, AS; Norvell, ST; Tai, J1
Weiss, RB1
Tisdale, MJ1
Woolley, PV1
Abrahamsen, AF; Hannisdal, E; Holte, H; Mella, O; Telhaug, R; Wist, E1
Hesseling, PB; Van Jaarsveld, D; Van Riet, FA; Wessels, G1
Calvo Villas, J; Ramírez Sánchez, M; Sicilia Guillén, F1
Carde, P; Cavalli, F; Diehl, V; Franklin, J1
Neville, F; Nystrom, ML; Oliver, RT; Shamash, J; Steele, JP1
Clawson, S; Cullen, MH; Hancock, BW; Jack, AS; Johnson, PW; MacLennan, KA; Radford, JA; Ryder, D; Smith, P; Stenning, SP; Sydes, MR; Walewski, J1
Bauder-Wüst, U; Eisenhut, M; Eskerski, H; Haberkorn, U; Wolf, M1
Bauer, K; Brillant, C; Engert, A; Herbst, C; Kluge, S; Monsef, I; Skoetz, N1
Hayward, J; Hewitt, M; McCarthy, K; Morland, B; Shankar, A; Visaduraki, M1
Gholizad, LM; Nejati, V; Oskooii, AE; Zare, S1
Daw, S; Hayward, J; Hewitt, M; Kirkwood, A; McCarthy, K; Morland, B; Shankar, A1
Asad, M; Mehreen, A; Ria, S; Sindhu, II; Wali, RM1

Reviews

4 review(s) available for chlorambucil and dacarbazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hypersensitivity reactions.
    Seminars in oncology, 1992, Volume: 19, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide

1992
Hepatic and pancreatic damage produced by cytotoxic drugs.
    Cancer treatment reviews, 1983, Volume: 10, Issue:2

    Topics: Aminoacridines; Amsacrine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azathioprine; Chlorambucil; Dacarbazine; Drug Therapy, Combination; Humans; Intercalating Agents; Liver; Mercaptopurine; Methotrexate; Nitrosourea Compounds; Pancreas; Plicamycin; Procarbazine; Pyrrolizidine Alkaloids; Streptozocin

1983
Is escalated BEACOPP a standard therapy for advanced Hodgkin's disease?
    The hematology journal : the official journal of the European Haematology Association, 2000, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials, Phase III as Topic; Cyclophosphamide; Dacarbazine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Granulocyte Colony-Stimulating Factor; Hematologic Diseases; Hodgkin Disease; Humans; Infertility; Mechlorethamine; Prednisolone; Prednisone; Procarbazine; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Safety; Treatment Outcome; Vinblastine; Vincristine

2000

Trials

5 trial(s) available for chlorambucil and dacarbazine

ArticleYear
[Chemotherapy of advanced prostate cancer].
    Voprosy onkologii, 1977, Volume: 23, Issue:12

    Topics: Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Diethylstilbestrol; Drug Evaluation; Drug Therapy, Combination; Estramustine; Fluorouracil; Humans; Hydroxyurea; Male; National Health Programs; Neoplasm Recurrence, Local; Prednisolone; Procarbazine; Prognosis; Prostatic Neoplasms; Streptozocin; Time Factors; United States

1977
ChlVPP is as effective as alternating ChlVPP/ABOD in advanced stage Hodgkin's disease.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35 Suppl 8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Doxorubicin; Drug Administration Schedule; Female; Hodgkin Disease; Humans; Male; Middle Aged; Prednisolone; Procarbazine; Prognosis; Treatment Outcome; Vinblastine; Vincristine

1996
Low-dose continuous chemotherapy for metastatic melanoma: a phase II trial.
    Melanoma research, 2003, Volume: 13, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Subcutaneous; Lomustine; Male; Melanoma; Methotrexate; Middle Aged; Neoplasm Metastasis; Prognosis; Tamoxifen; Time Factors; Treatment Outcome; Vinblastine

2003
Comparison of ABVD and alternating or hybrid multidrug regimens for the treatment of advanced Hodgkin's lymphoma: results of the United Kingdom Lymphoma Group LY09 Trial (ISRCTN97144519).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-20, Volume: 23, Issue:36

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Combined Modality Therapy; Dacarbazine; Disease Progression; Disease-Free Survival; Doxorubicin; Drug Resistance, Multiple; Etoposide; Female; Hodgkin Disease; Humans; Male; Middle Aged; Prednisolone; Procarbazine; Treatment Outcome; Vinblastine; Vincristine

2005
Clinical outcome in children and adolescents with Hodgkin lymphoma after treatment with chemotherapy alone - the results of the United Kingdom HD3 national cohort trial.
    European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Chlorambucil; Cohort Studies; Dacarbazine; Doxorubicin; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Prednisolone; Procarbazine; Prognosis; Salvage Therapy; Survival Analysis; Treatment Outcome; United Kingdom; Vinblastine

2012

Other Studies

18 other study(ies) available for chlorambucil and dacarbazine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The carcinogenic properties of some of the principal drugs used in clinical cancer chemotherapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1975, Issue:52

    Topics: Animals; Antineoplastic Agents; Carcinogens; Chlorambucil; Cyclophosphamide; Dacarbazine; Dactinomycin; Diethylnitrosamine; Female; Humans; Male; Melphalan; Mice; Mitobronitol; Mitolactol; Mitomycins; Neoplasms, Experimental; Nitrogen Mustard Compounds; Picolinic Acids; Procarbazine; Rats; Streptozocin; Uracil Mustard

1975
Adjuvant treatment of soft tissue sarcoma in children and adults.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dacarbazine; Dactinomycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Methotrexate; Neoplasm Staging; Sarcoma; Soft Tissue Neoplasms; Urogenital Neoplasms; Vincristine

1978
Comparison of various forms of therapy in two different mouse tumor systems.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Animals; BCG Vaccine; Chlorambucil; Complement System Proteins; Dacarbazine; Female; Goats; Immunoglobulins; Immunotherapy; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Rabbits

1979
Residual marrow injury following cytotoxic drugs.
    Leukemia research, 1979, Volume: 3, Issue:4

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Chlorambucil; Dacarbazine; Doxorubicin; Female; Granulocytes; Hematopoietic Stem Cells; Mechlorethamine; Melphalan; Mice; Mice, Inbred BALB C; Mitomycins

1979
Immunochemotherapy of malignant melanoma with chlorambucil-bound antimelanoma globulins: preliminary results in patients with disseminated disease.
    Journal of the National Cancer Institute, 1977, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Aged; Antibodies, Neoplasm; Chlorambucil; Dacarbazine; Female; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunotherapy; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms

1977
Antitumor imidazotetrazines--XV. Role of guanine O6 alkylation in the mechanism of cytotoxicity of imidazotetrazinones.
    Biochemical pharmacology, 1987, Feb-15, Volume: 36, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Chlorambucil; Colonic Neoplasms; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Guanine; Humans; Imidazoles; Kinetics; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Methyltransferases; Mice; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Temozolomide

1987
Hodgkin's disease in children in southern Africa: epidemiological characteristics, morbidity and long-term outcome.
    Annals of tropical paediatrics, 1997, Volume: 17, Issue:4

    Topics: Adolescent; Age Distribution; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Chlorambucil; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Morbidity; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Retrospective Studies; South Africa; Survival Rate; Treatment Outcome; Vinblastine; Vincristine

1997
[Chronic lymphatic leukemia and Hodgkin's disease].
    Sangre, 1999, Volume: 44, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Doxorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Neoplasms, Second Primary; Prednisone; Remission Induction; Vidarabine; Vinblastine

1999
Alkylating benzamides with melanoma cytotoxicity: experimental chemotherapy in a mouse melanoma model.
    Melanoma research, 2006, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Benzamides; Chlorambucil; Dacarbazine; Disease Models, Animal; Humans; Injections, Intraperitoneal; Male; Maximum Tolerated Dose; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Skin Neoplasms; Survival Rate; Tumor Cells, Cultured

2006
Eleventh biannual report of the Cochrane Haematological Malignancies Group: Focus on Hodgkin lymphoma.
    Journal of the National Cancer Institute, 2010, Jun-16, Volume: 102, Issue:12

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bendamustine Hydrochloride; Bleomycin; Chlorambucil; Controlled Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Exercise; Hematinics; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Multicenter Studies as Topic; Myelodysplastic Syndromes; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Quality of Life; Randomized Controlled Trials as Topic; Vinblastine; Vincristine

2010
A comparison of effects of ABVD and ChlVPP chemotherapeutic protocols for Hodgkin's disease on rats' epididiymal and testicular tissues.
    Pakistan journal of biological sciences : PJBS, 2010, Sep-15, Volume: 13, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Disease Models, Animal; Doxorubicin; Epididymis; Humans; Male; Prednisone; Procarbazine; Rats; Testis; Vinblastine

2010
Treatment outcome in children and adolescents with relapsed Hodgkin lymphoma--results of the UK HD3 relapse treatment strategy.
    British journal of haematology, 2014, Volume: 165, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Child; Chlorambucil; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Dexamethasone; Disease-Free Survival; Doxorubicin; Epirubicin; Etoposide; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Hodgkin Disease; Humans; Ifosfamide; Kaplan-Meier Estimate; Melphalan; Multicenter Studies as Topic; Neoplasm Staging; Prednisolone; Prednisone; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vinblastine; Vincristine

2014
Retrospective analysis of clinical features and treatment outcomes of children with Hodgkin's Lymphoma treated with different chemotherapy protocols at a tertiary care center in Pakistan.
    JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dacarbazine; Doxorubicin; Etoposide; Female; Hodgkin Disease; Humans; Infant; Kaplan-Meier Estimate; Male; Neoplasm Staging; Pakistan; Prednisolone; Prednisone; Procarbazine; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Survival Rate; Tertiary Care Centers; Treatment Outcome; Vinblastine; Vincristine

2019