chlorambucil and colchicine

chlorambucil has been researched along with colchicine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199017 (51.52)18.7374
1990's3 (9.09)18.2507
2000's7 (21.21)29.6817
2010's6 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Greene, LM; Greene, TF; Malebari, AM; McCabe, T; Meegan, MJ; Nathwani, SM; O'Boyle, NM; Pollock, JK; Twamley, B; Wang, S; Zisterer, DM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ben-David, G; Firer, MA; Gancz, A; Gellerman, G; Gilad, Y; Luboshits, G; Minnes, R; Senderowitz, H; Tuchinsky, H1
Brodie, AE; Potter, J; Reed, DJ1
Ates, Y; Sentein, P1
Missmahl, HP; Willemsen, M1
Bahgat, MH; Gadallah, MA; Ghali, AF; Osman, LM; Sabbour, MS1
Lauchart, W; Weber, P; Wiedmann, KH1
Adams, D; Clements, D; Elias, E1
Benezra, D; Cohen, E1
Kaplan, MM1
Warnes, TW1
Danieli, G1
Leĭkina, FI; Smolianskaia, AZ1
Dendy, PP1
Jacobs, EM; Johnson, FD1
Shepard, TH1
Sokal, JE; Stutzman, L1
Sporny, S1
Ahmed, FB; Gumpel, JM; Leonard, N; Price, AB; Steuer, A1
Heathcote, EJ1
Kaklamani, VG; Kaklamanis, PG1
LOPESCARDOZO, E1
Ben Ghorbel, I; Houman, MH; Khanfir, M1

Reviews

7 review(s) available for chlorambucil and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[What is safe in therapy of primary biliary cirrhosis?].
    Der Internist, 1988, Volume: 29, Issue:11

    Topics: Bile Acids and Salts; Chlorambucil; Colchicine; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Transplantation; Prednisolone

1988
The treatment of primary biliary cirrhosis.
    Journal of clinical and hospital pharmacy, 1986, Volume: 11, Issue:2

    Topics: Adrenal Cortex Hormones; Antipruritics; Azathioprine; Celiac Disease; Chlorambucil; Colchicine; Cyclosporins; Humans; Levamisole; Liver Cirrhosis, Biliary; Liver Transplantation; Osteomalacia; Penicillamine; Pruritus; Zinc

1986
Treatment of primary biliary cirrhosis.
    Seminars in liver disease, 1985, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine; Cyclosporins; Female; Humans; Hyperlipidemias; Hypertension, Portal; Levamisole; Liver Cirrhosis, Biliary; Liver Transplantation; Nutrition Disorders; Osteomalacia; Osteoporosis; Penicillamine; Pruritus; Trientine; Vitamin A Deficiency; Vitamin E Deficiency; Zinc

1985
Use of anticancer drugs during pregnancy.
    Clinical obstetrics and gynecology, 1968, Volume: 11, Issue:2

    Topics: Alkylating Agents; Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Busulfan; Chlorambucil; Choriocarcinoma; Colchicine; Female; Fetal Death; Folic Acid Antagonists; Gestational Age; Humans; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Pregnancy; Pregnancy Complications; Urethane; Vinblastine

1968
[Current theories on the possibilities of treatment of amyloidosis].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Jul-15, Volume: 34, Issue:14

    Topics: Amyloidosis; Chlorambucil; Colchicine; Dimethyl Sulfoxide; Humans; Melphalan

1981
Evidence-based therapy of primary biliary cirrhosis.
    European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:6

    Topics: Azathioprine; Bile Acids and Salts; Chlorambucil; Colchicine; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Prednisolone; Treatment Outcome

1999

Trials

1 trial(s) available for chlorambucil and colchicine

ArticleYear
Another treatment for primary biliary cirrhosis.
    Gastroenterology, 1987, Volume: 92, Issue:1

    Topics: Azathioprine; Chlorambucil; Colchicine; Humans; Liver Cirrhosis, Biliary

1987

Other Studies

25 other study(ies) available for chlorambucil and colchicine

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.
    Journal of medicinal chemistry, 2016, Jan-14, Volume: 59, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Azetidines; beta-Lactams; Binding Sites; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; G2 Phase; Humans; Microtubules; Models, Molecular; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2016
Discovery of potent molecular chimera (CM358) to treat human metastatic melanoma.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Humans; Melanoma; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Pyrimidinones; Structure-Activity Relationship; Topoisomerase II Inhibitors

2017
Effects of vinblastine, oncodazole, procarbazine, chlorambucil, and bleomycin in vivo on colchicine binding activity of tubulin.
    Life sciences, 1979, Apr-23, Volume: 24, Issue:17

    Topics: Animals; Antineoplastic Agents; Benzimidazoles; Bleomycin; Carbamates; Chlorambucil; Colchicine; Leukemia, Experimental; Male; Mice; Mitosis; Procarbazine; Protein Binding; Time Factors; Tubulin; Vinblastine

1979
Cytological characteristics and classification of spindle inhibitors according to their effects on segmentation mitoses.
    La Cellule, 1978, Volume: 72, Issue:3

    Topics: Amides; Amphibians; Animals; Carbamates; Carboxylic Acids; Cell Cycle; Cell Nucleus; Chloral Hydrate; Chlorambucil; Colchicine; Cycloheximide; Metaphase; Microtubules; Mitosis; Pyrans; Quinolines

1978
[Therapy of amyloidoses].
    Deutsche medizinische Wochenschrift (1946), 1977, Nov-04, Volume: 102, Issue:44

    Topics: Amyloidosis; Azathioprine; Chlorambucil; Colchicine; Humans; Penicillamine

1977
Comparative study of different types of treatments in chronic active hepatitis.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1985, Volume: 4, Issue:3

    Topics: Adrenal Cortex Hormones; Age Factors; Azathioprine; Chlorambucil; Colchicine; Drug Therapy, Combination; Fluorouracil; Hepatitis B Surface Antigens; Hepatitis, Chronic; Humans; Inosine Pranobex

1985
Treatment and visual prognosis in Behçet's disease.
    The British journal of ophthalmology, 1986, Volume: 70, Issue:8

    Topics: Azathioprine; Behcet Syndrome; Chlorambucil; Colchicine; Female; Humans; Male; Prednisone; Prognosis; Visual Acuity

1986
[1973 treatment of acute leukemias].
    Minerva medica, 1974, Dec-15, Volume: 65, Issue:90

    Topics: Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Vinblastine; Vincristine

1974
[Detection of a moderate staphylococcal phage by means of antineoplastic agents].
    Antibiotiki, 1970, Volume: 15, Issue:6

    Topics: Aminopterin; Antibiotics, Antineoplastic; Anticholesteremic Agents; Antimetabolites; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Dactinomycin; Drug Resistance, Microbial; Flavonoids; Fluorouracil; Lysogeny; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Olivomycins; Staphylococcus; Staphylococcus Phages; Thiotepa; Ultraviolet Rays; Uracil; Vinblastine; Vincristine

1970
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine

1968
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
    Cancer, 1971, Volume: 27, Issue:6

    Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neoplasms; Female; Floxuridine; Humans; Hydroxyurea; Idoxuridine; Male; Melanoma; Melphalan; Middle Aged; Neoplasm Metastasis; Nitrogen Mustard Compounds; Nitrosourea Compounds; Skin Neoplasms; Vinblastine; Vincristine; Vulvar Neoplasms

1971
Teratogenicity from drugs--an increasing problem.
    Disease-a-month : DM, 1974

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bacterial Agents; Azathioprine; Azauridine; Busulfan; Chlorambucil; Colchicine; Contraceptives, Oral; Cyclophosphamide; Diethylstilbestrol; Ethanol; Female; Fetus; Genotype; Humans; Iodine Radioisotopes; Mercaptopurine; Methotrexate; Mice; Nitrogen Mustard Compounds; Phenotype; Pregnancy; Pregnancy, Animal; Prenatal Diagnosis; Radiation Genetics; Rats; Species Specificity; Thalidomide; Tranquilizing Agents

1974
An unusual case of familial Mediterranean fever.
    British journal of rheumatology, 1997, Volume: 36, Issue:10

    Topics: Abdominal Pain; Amyloidosis; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Arthritis; Chlorambucil; Colchicine; Colitis, Ischemic; Diagnosis, Differential; Familial Mediterranean Fever; Female; Humans; Ileum; Middle Aged; Radiography; Renal Insufficiency

1997
Treatment of Behçet's disease--an update.
    Seminars in arthritis and rheumatism, 2001, Volume: 30, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Behcet Syndrome; Chlorambucil; Colchicine; Cyclophosphamide; Cyclosporine; Dapsone; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferons; Levamisole; Male; Methotrexate; Pentoxifylline; Recombinant Proteins; Recurrence; Sulfasalazine; Thalidomide

2001
[CYTOSTATIC THERAPY].
    Geneeskundige bladen uit kliniek en laboratorium voor de praktijk, 1964, Volume: 51

    Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Female; Folic Acid Antagonists; Genetic Diseases, X-Linked; Humans; Intestinal Neoplasms; Leukemia; Leukemia, Hairy Cell; Lung Neoplasms; Lymphatic Diseases; Nitrogen Mustard Compounds; Ovarian Neoplasms; Purines; Pyrimidines; Severe Combined Immunodeficiency; Stomach Neoplasms; Thiotepa; Toxicology; Urethane; Urogenital Neoplasms; Vinblastine

1964
[Amyloidosis in adult onset Still's disease].
    La Revue de medecine interne, 2004, Volume: 25, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Amyloidosis; Chlorambucil; Colchicine; Drug Therapy, Combination; Female; Follow-Up Studies; Gout Suppressants; Humans; Kidney Diseases; Prognosis; Still's Disease, Adult-Onset; Time Factors; Treatment Outcome

2004