chlorambucil and amsacrine

chlorambucil has been researched along with amsacrine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RF; Denny, WA; Thompson, LH; Wilson, WR1
Flanagan, JU; Kemp, CA; Maréchal, JD; Paine, MJ; Roberts, GC; Sutcliffe, MJ; van Eldik, AJ; Wolf, CR1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ehrsson, H; Eksborg, S1
Woolley, PV1
Cairns, MJ; Denny, WA; Murray, V; Temple, MD1
Davey, M; Davey, R; Locke, V1

Reviews

2 review(s) available for chlorambucil and amsacrine

ArticleYear
Drug level monitoring: cytostatics.
    Journal of chromatography, 1985, May-10, Volume: 340

    Topics: Alkylating Agents; Aminoacridines; Amsacrine; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Busulfan; Chlorambucil; Chromatography, Gas; Chromatography, Liquid; Cisplatin; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Mass Spectrometry; Melphalan; Methotrexate; Mitomycins; Monitoring, Physiologic; Nitrosourea Compounds; Podophyllotoxin; Purines; Thiotepa; Vinca Alkaloids

1985
Hepatic and pancreatic damage produced by cytotoxic drugs.
    Cancer treatment reviews, 1983, Volume: 10, Issue:2

    Topics: Aminoacridines; Amsacrine; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azathioprine; Chlorambucil; Dacarbazine; Drug Therapy, Combination; Humans; Intercalating Agents; Liver; Mercaptopurine; Methotrexate; Nitrosourea Compounds; Pancreas; Plicamycin; Procarbazine; Pyrrolizidine Alkaloids; Streptozocin

1983

Other Studies

8 other study(ies) available for chlorambucil and amsacrine

ArticleYear
Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:1

    Topics: Aminoacridines; Animals; Cell Division; Cell Line; DNA; Nitracrine; Oxygen; Structure-Activity Relationship

1989
Validation of model of cytochrome P450 2D6: an in silico tool for predicting metabolism and inhibition.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Binding Sites; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Databases, Factual; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Protein-DNA interactions in the human beta-globin locus control region hypersensitive site-2 as revealed by four nitrogen mustards.
    Nucleic acids research, 1997, Aug-15, Volume: 25, Issue:16

    Topics: Aminacrine; Amsacrine; Cell Line; Chlorambucil; Chromatin; DNA Damage; DNA-Binding Proteins; Gene Expression Regulation; Globins; Humans; Mechlorethamine; Promoter Regions, Genetic

1997
Paclitaxel sensitization of multidrug-resistant cells to chemotherapy is independent of the cell cycle.
    Cytometry, 2001, Mar-01, Volume: 43, Issue:3

    Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carcinoma, Small Cell; Cell Cycle; Cell Survival; Chlorambucil; Cisplatin; Daunorubicin; Drug Resistance, Multiple; Epirubicin; Genistein; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2001