chlorambucil and abt-199

chlorambucil has been researched along with abt-199 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (15.38)24.3611
2020's11 (84.62)2.80

Authors

AuthorsStudies
Al-Sawaf, O; Bahlo, J; Boettcher, S; Dixon, M; Eichhorst, B; Fink, AM; Fischer, K; Fogliatto, LM; Goede, V; Hallek, M; Humerickhouse, R; Humphrey, K; Kipps, TJ; Kreuzer, KA; Langerak, AW; Le Dû, K; Liberati, AM; Mobasher, M; Niemann, CU; Opat, S; Pinilla-Ibarz, J; Ritgen, M; Robinson, S; Robrecht, S; Samoylova, O; Sivcheva, L; Stilgenbauer, S; Tandon, M; Tausch, E; Warburton, S; Weinkove, R; Wendtner, CM1
Andreadis, C; Fakhri, B1
Al-Sawaf, O; Bahlo, J; Bloehdorn, J; Bullinger, L; Döhner, H; Dolnik, A; Eichhorst, B; Fink, AM; Fischer, K; Hallek, M; Humphrey, K; Jiang, Y; Kneba, M; Kreuzer, KA; Lurà, MP; Mertens, D; Ritgen, M; Robrecht, S; Schary, W; Schneider, C; Stilgenbauer, S; Tandon, M; Tausch, E; Zhang, C1
Gao, A; Gao, W; Huo, D; Ran, X; Sheng, Z; Song, S; Yu, M; Zhu, H1
Seymour, JF1
Al-Sawaf, O; Eichhorst, B; Fink, AM; Fischer, K; Fogliatto, LM; Hallek, M; Kipps, TJ; Kreuzer, KA; Le Dû, K; Liberati, AM; Niemann, CU; Opat, S; Pinilla-Ibarz, J; Ritgen, M; Robinson, S; Robrecht, S; Samoylova, O; Schary, W; Sinha, A; Sivcheva, L; Stilgenbauer, S; Tandon, M; Tausch, E; Weinkove, R; Wendtner, CM; Zhang, C1
De la Serna-Torroba, J; Escudero-Vilaplana, V; Hernández-Rivas, JÁ; Moreno-Martínez, E; Sánchez-Cuervo, M; Sánchez-Hernández, R1
Messori, A1
Do, N; Thielen, FW1
Al-Sawaf, O; Balasubramanian, S; Chang, YM; Choi, Y; Chyla, B; Eichhorst, B; Fink, AM; Fischer, K; Frenzel, LP; Hallek, M; Jiang, Y; Jin, HY; Kotak, A; Kreuzer, KA; Pallasch, CP; Paulson, JN; Peifer, M; Ritgen, M; Robrecht, S; Schneider, C; Stilgenbauer, S; Tausch, E; Zhang, C1
Romero, D1
Baeten, K; Benjamini, O; Caces, DB; Follows, G; Howes, A; Janssens, A; Kater, AP; Levin, MD; Moreno, C; Munir, T; Niemann, CU; Osterborg, A; Owen, C; Parisi, L; Qi, K; Qi, Q; Robak, T; Schuier, N; Simkovic, M; Srinivasan, S; Stevens, D; Voloshin, S; Vorobyev, V; Yagci, M; Ysebaert, L1
Baeten, K; Benjamini, O; Caces, DB; Follows, GA; Howes, A; Janssens, A; Kater, AP; Levin, MD; Moreno, C; Munir, T; Niemann, CU; Owen, C; Parisi, L; Qi, K; Qi, Q; Robak, T; Schuier, N; Simkovic, M; Sinet, P; Srinivasan, S; Voloshin, S; Vorobyev, V; Yagci, M; Ysebaert, L1

Reviews

1 review(s) available for chlorambucil and abt-199

ArticleYear
Comparison of acalabrutinib plus obinutuzumab, ibrutinib plus obinutuzumab and venetoclax plus obinutuzumab for untreated CLL: a network meta-analysis.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:14

    Topics: Adenine; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Network Meta-Analysis; Piperidines; Prospective Studies; Pyrazines; Sulfonamides

2020

Trials

3 trial(s) available for chlorambucil and abt-199

ArticleYear
Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Progression-Free Survival; Sulfonamides; Treatment Outcome

2020
Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia.
    Nature communications, 2023, 04-18, Volume: 14, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Transcriptome

2023
Fixed-duration ibrutinib-venetoclax versus chlorambucil-obinutuzumab in previously untreated chronic lymphocytic leukaemia (GLOW): 4-year follow-up from a multicentre, open-label, randomised, phase 3 trial.
    The Lancet. Oncology, 2023, Volume: 24, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Pneumonia

2023

Other Studies

9 other study(ies) available for chlorambucil and abt-199

ArticleYear
Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions.
    The New England journal of medicine, 2019, Jun-06, Volume: 380, Issue:23

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Comorbidity; Female; Humans; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Progression-Free Survival; Sulfonamides

2019
CLL14 Trial: Fixed-Duration Chemotherapy-Free Regimen for Frail Patients with Treatment-Naïve CLL.
    Oncology (Williston Park, N.Y.), 2019, Nov-14, Volume: 33, Issue:11

    Topics: Adenine; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Clinical Trials, Phase III as Topic; Frail Elderly; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Piperidines; Pyrazoles; Pyrimidines; Sulfonamides; Survival Rate; Treatment Outcome

2019
Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
    Blood, 2020, 06-25, Volume: 135, Issue:26

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Chromosome Aberrations; Clinical Trials, Phase III as Topic; Follow-Up Studies; Genes, Neoplasm; Genetic Markers; Humans; Immunoglobulin Heavy Chains; Immunoglobulin Variable Region; Kaplan-Meier Estimate; Leukemia, Lymphocytic, Chronic, B-Cell; Multicenter Studies as Topic; Mutation; Neoplasm, Residual; Prognosis; Progression-Free Survival; Remission Induction; Sulfonamides

2020
Venetoclax plus obinutuzumab therapy for front-line treatment of chronic lymphocytic leukaemia.
    The Lancet. Oncology, 2020, Volume: 21, Issue:9

    Topics: Antibodies, Monoclonal, Humanized; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Sulfonamides

2020
Cost-utility analysis of venetoclax in combination with obinutuzumab as first-line treatment of chronic lymphocytic leukaemia in Spain.
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 04-27, Volume: 46, Issue:3

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Cost-Benefit Analysis; Cyclophosphamide; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Quality of Life; Rituximab; Spain; Sulfonamides

2022
Long-term progression-free survival in patients with chronic lymphocytic leukemia treated with novel agents: An analysis based on indirect comparisons.
    European journal of haematology, 2023, Volume: 110, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artificial Intelligence; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Progression-Free Survival; Rituximab

2023
Cost-Effectiveness of Venetoclax Plus Obinutuzumab Versus Chlorambucil Plus Obinutuzumab for the First-Line Treatment of Adult Patients With Chronic Lymphocytic Leukemia: An Extended Societal View.
    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023, Volume: 26, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cost-Benefit Analysis; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Quality-Adjusted Life Years

2023
Venetoclax-obinutuzumab combinations are effective in fit patients with CLL.
    Nature reviews. Clinical oncology, 2023, Volume: 20, Issue:8

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell

2023
Impact of Minimal Residual Disease on Progression-Free Survival Outcomes After Fixed-Duration Ibrutinib-Venetoclax Versus Chlorambucil-Obinutuzumab in the GLOW Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 07-20, Volume: 41, Issue:21

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm, Residual; Progression-Free Survival

2023