Compounds > chlorambucil

chlorambucil and 4-n-bis(2-chloroethyl)aminobenzoic acid

chlorambucil has been researched along with 4-n-bis(2-chloroethyl)aminobenzoic acid in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Leo, A; Panthananickal, A1
Chen, ZS; Li, D; Pei, L; Sun, Y; Wang, C; Wu, X; Xu, J; Xu, S; Yao, H; Zhang, YK1
Han, T; Hu, X; Hua, H; Jiao, R; Li, D; Li, Z; Liu, W; Wang, Y; Xu, F; Xue, J1
Gao, X; Hua, H; Li, D; Li, J; Li, Z; Liu, W; Wang, M; Xu, J; Xu, S; Zang, L1
Gao, M; Han, T; Hua, H; Li, D; Li, Z; Liu, Y; Pan, H; Tian, K; Uchita, T; Xu, F1
Bai, J; Cheng, K; Gao, X; Han, T; Hua, H; Li, D; Li, X; Li, Z; Wang, M; Wang, Y1
Bagshawe, KD; Hartley, JA; Souhami, RL; Springer, CJ; Sunters, A1

Other Studies

7 other study(ies) available for chlorambucil and 4-n-bis(2-chloroethyl)aminobenzoic acid

ArticleYear
Structure-activity relationships in antitumor aniline mustards.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:1

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Hydrolysis; Lethal Dose 50; Leukemia L1210; Leukemia, Experimental; Mice; Models, Biological; Nitrogen Mustard Compounds; Rats; Structure-Activity Relationship

1978
Novel hybrids of natural oridonin-bearing nitrogen mustards as potential anticancer drug candidates.
    ACS medicinal chemistry letters, 2014, Jul-10, Volume: 5, Issue:7

    Topics:

2014
Design and synthesis of novel nitrogen mustard-evodiamine hybrids with selective antiproliferative activity.
    Bioorganic & medicinal chemistry letters, 2017, 11-15, Volume: 27, Issue:22

    Topics: Antineoplastic Agents; Carbolines; Cell Cycle Checkpoints; Cell Line; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Mechlorethamine; Quinazolines; Quinazolinones; Structure-Activity Relationship

2017
Novel enmein-type diterpenoid hybrids coupled with nitrogen mustards: Synthesis of promising candidates for anticancer therapeutics.
    European journal of medicinal chemistry, 2018, Feb-25, Volume: 146

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mechlorethamine; Membrane Potential, Mitochondrial; Molecular Structure; Structure-Activity Relationship

2018
Novel hybrids of brefeldin A and nitrogen mustards with improved antiproliferative selectivity: Design, synthesis and antitumor biological evaluation.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Antineoplastic Agents; Brefeldin A; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Mechlorethamine; Molecular Structure; Structure-Activity Relationship

2018
Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Antineoplastic Agents; Apigenin; Apoptosis; Apoptosis Regulatory Proteins; Benzoic Acid; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Signal Transduction

2018
The cytotoxicity, DNA crosslinking ability and DNA sequence selectivity of the aniline mustards melphalan, chlorambucil and 4-[bis(2-chloroethyl)amino] benzoic acid.
    Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1

    Topics: 4-Aminobenzoic Acid; Alkylation; Binding Sites; Cell Survival; Chlorambucil; Cross-Linking Reagents; DNA; Humans; Melphalan; Nitrogen Mustard Compounds; para-Aminobenzoates; Tumor Cells, Cultured

1992