chloral hydrate has been researched along with trichloroethylene in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (49.15) | 18.7374 |
| 1990's | 15 (25.42) | 18.2507 |
| 2000's | 12 (20.34) | 29.6817 |
| 2010's | 3 (5.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Cole, WJ; Mitchell, RG; Salamonsen, RF | 1 |
| Aschan, G; Bertler, A; Hydén, D; Larsby, B; Norlander, B; Odkvist, LM; Tham, R | 1 |
| Dallmeier, E; Fetz, H; Henschler, D; Hoos, WR; Metzler, M | 1 |
| Nomiyama, H; Nomiyama, K; Uchiki, H | 1 |
| Gubéran, E | 1 |
| Elovaara, E; Gelboin, HV; Katakura, Y; Kishi, R; Nakajima, T; Park, SS; Vainio, H; Wang, RS | 1 |
| Elovaara, E; Gelboin, HV; Nakajima, T; Park, SS; Vainio, H; Wang, RS | 1 |
| Newman, LM; Wackett, LP | 1 |
| Murayama, N; Nakajima, T; Sato, A; Wang, RS | 1 |
| Klaunig, JE; Lin, EL; Ruch, RJ | 1 |
| Hobara, T; Iwamoto, S; Kawamoto, T; Kobayashi, H; Sakai, T | 2 |
| Heck, HD; Keller, DA | 1 |
| Christensen, JM; Dalgaard, L; Køppen, B | 1 |
| Hobara, T; Imamura, A; Iwamoto, S; Kawamoto, T; Kobayashi, H; Koshiro, A; Sakai, T | 1 |
| Carere, A; Conti, G; Conti, L; Crebelli, R | 1 |
| Brown, BR; Kelley, JM | 1 |
| Müller, G; Urban, T | 1 |
| Mikiska, A; Mikisková, H | 1 |
| Leibman, KC | 1 |
| Henschler, D; Müller, G; Spassovski, M | 1 |
| Ertle, T; Henschler, D; Müller, G; Spassowski, M | 1 |
| Eben, A; Kimmerle, G | 2 |
| Ogata, M; Saeki, T | 1 |
| Yllner, S | 1 |
| Byington, KH; Leibman, KC | 1 |
| Metalli, P; Pacchierotti, F; Russo, A | 1 |
| Chmara, D; Faure, J; Gu, ZW; Jalbert, P; Marka, C; Sele, B; Vincent, F; Vincent, M | 1 |
| Carlson, GP; White, JF | 1 |
| Ikeda, M; Miyake, Y; Ogata, M; Ohmori, S | 1 |
| DeSesso, JM; Steinberg, AD | 1 |
| Steinberg, AD | 1 |
| Langonné, I; Sabaté, JP; Saillenfait, AM | 1 |
| Foster, JR; Green, T; Mainwaring, GW | 1 |
| Abbas, R; Fisher, JW | 1 |
| Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC | 1 |
| Dawson, BV; Goldberg, SJ; Johnson, PD | 1 |
| Nakamura, K; Takano, T; Watanabe, M | 1 |
| Bull, RJ; Gonzalez-Leon, A; Merdink, JL; Schultz, IR | 1 |
| Burton, GA; Fisher, JW; Greenberg, MS | 1 |
| Honma, T; Nakajima, T; Wang, RS | 1 |
| Cummings, BS; Lash, LH | 1 |
| Cummings, BS; Lash, LH; Parker, JC | 1 |
| Forkert, PG; Lash, LH; Nadeau, V; Simmonds, A; Tardif, R | 1 |
| Deng, YY; Huang, JX; Li, LY; Tang, XJ | 1 |
| MARSHALL, EK; OWENS, AH | 1 |
| ARGENT, DE | 1 |
| Gilbert, KM; Pumford, NR; Whitlow, AB | 1 |
| Anupriwan, A; Forkert, PG; Leader, A; Tanphaichitr, N; Vincent, R; Wade, MG; Weerachatyanukul, W; Xu, H | 1 |
| Bartlett, MG; Bruckner, JV; Delinsky, AD | 1 |
| Baldwin, RM; Collins, KS; Forkert, PG; Lash, LH; Millen, B; Putt, DA; Shultz, MA | 1 |
| Bronley-DeLancey, A; Hoel, DG; Jollow, DJ; McMillan, DC; McMillan, JM; Mohr, LC | 1 |
| Chiu, WA; Clewell, HJ; Hack, CE; Jay Zhao, Q | 1 |
| Caldwell, JC; Keshava, N | 1 |
| Blossom, SJ; Doss, JC; Gilbert, KM | 1 |
| Huang, H; Huang, Y; Huang, Z; Jin, J; Wu, Q; Xia, L; Zeng, Z; Zhou, S | 1 |
5 review(s) available for chloral hydrate and trichloroethylene
| Article | Year |
|---|---|
Biotransformation of trichloroethylene.
Topics: Anesthesia, Inhalation; Animals; Biotransformation; Carbon Monoxide; Chloral Hydrate; Chlorine; Cytochrome P-450 Enzyme System; Disulfiram; Drug Interactions; Drug Synergism; Enzyme Induction; Ethanol; Humans; In Vitro Techniques; Liver; Microsomes, Liver; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Partial Pressure; Protein Binding; Radioisotopes; Trichloroacetic Acid; Trichloroethylene | 1974 |
Have animal data been used inappropriately to estimate risks to humans from environmental trichloroethylene?
Topics: Animals; Chloral Hydrate; Environmental Pollutants; Humans; Neoplasms, Experimental; Risk Factors; Trichloroethylene | 1993 |
Should chloral hydrate be banned?
Topics: Adult; Animals; Carcinogenicity Tests; Carcinogens, Environmental; Child; Chloral Hydrate; Drug and Narcotic Control; Humans; Infant, Newborn; Trichloroethylene; United States; United States Food and Drug Administration | 1993 |
A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid.
Topics: Animals; Chloral Hydrate; Chromatography, Gas; Chromatography, Liquid; Dichloroacetic Acid; Humans; Mass Spectrometry; Trichloroacetic Acid; Trichloroethylene | 2005 |
Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.
Topics: Animals; Carcinogenicity Tests; Chloral Hydrate; Cysteine; Dichloroacetic Acid; Environmental Pollutants; History, 21st Century; Humans; Kidney Neoplasms; Liver Neoplasms; Risk Assessment; Risk Factors; Signal Transduction; Trichloroacetic Acid; Trichloroethylene; United States | 2006 |
1 trial(s) available for chloral hydrate and trichloroethylene
| Article | Year |
|---|---|
Trichloroethylene Hypersensitivity Syndrome Is Potentially Mediated through Its Metabolite Chloral Hydrate.
Topics: Adult; Allergens; Chloral Hydrate; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Occupational Exposure; Trichloroethylene | 2015 |
53 other study(ies) available for chloral hydrate and trichloroethylene
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography.
Topics: Anesthesia; Chloral Hydrate; Chromatography, Gas; Humans; Mass Spectrometry; Time Factors; Trichloroethylene | 1975 |
The influence of trichloroethylene and related drugs on the vestibular system.
Topics: Animals; Chloral Hydrate; Chloralose; Chromatography, Gas; Ethylene Chlorohydrin; Eye Movements; Models, Biological; Rabbits; Solvents; Trichloroethylene; Vestibular Function Tests; Vestibule, Labyrinth | 1979 |
Reactions of trichloroethylene epoxide in aqueous systems.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Chloral Hydrate; Drug Stability; Epoxy Compounds; Formates; Glyoxylates; Trichloroacetic Acid; Trichloroethylene; Water | 1979 |
Gas-liquid chromatographic determination of trichloroethylene metabolites in urine.
Topics: Air Pollutants, Occupational; Animals; Chloral Hydrate; Chromatography, Gas; Environmental Exposure; Rats; Trichloroacetic Acid; Trichloroethylene | 1978 |
Proposed biological threshold limit values for industrial exposure to trichloroethylene vapor.
Topics: Chloral Hydrate; Environmental Exposure; Ethanol; Humans; Mathematics; Models, Biological; Occupational Medicine; Trichloroacetic Acid; Trichloroethylene | 1977 |
Sex-, age- and pregnancy-induced changes in the metabolism of toluene and trichloroethylene in rat liver in relation to the regulation of cytochrome P450IIE1 and P450IIC11 content.
Topics: Aging; Analgesics; Animals; Antibodies, Monoclonal; Benzyl Alcohol; Benzyl Alcohols; Chloral Hydrate; Cytochrome P-450 Enzyme System; Female; Isoenzymes; Liver; Male; Pregnancy; Rats; Rats, Inbred Strains; Sex Factors; Toluene; Trichloroethylene | 1992 |
A comparative study on the contribution of cytochrome P450 isozymes to metabolism of benzene, toluene and trichloroethylene in rat liver.
Topics: Animals; Antibodies, Monoclonal; Benzene; Chloral Hydrate; Cytochrome P-450 Enzyme System; Ethanol; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Toluene; Trichloroethylene | 1992 |
Fate of 2,2,2-trichloroacetaldehyde (chloral hydrate) produced during trichloroethylene oxidation by methanotrophs.
Topics: Chloral Hydrate; Methylococcaceae; Oxidation-Reduction; Oxygenases; Trichloroethylene | 1991 |
Three forms of trichloroethylene-metabolizing enzymes in rat liver induced by ethanol, phenobarbital, and 3-methylcholanthrene.
Topics: Animals; Chloral Hydrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Hydroxylation; Isoenzymes; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Trichloroethylene | 1990 |
Effects of trichloroethylene and its metabolites on rodent hepatocyte intercellular communication.
Topics: Animals; Cell Communication; Cells, Cultured; Chloral Hydrate; Liver; Male; Mice; Mice, Inbred Strains; Pyridines; Rats; Rats, Inbred F344; Species Specificity; Trichloroacetic Acid; Trichloroethylene | 1989 |
The absorption of trichloroethylene and its metabolites from the urinary bladder of anesthetized dogs.
Topics: Animals; Bile; Chloral Hydrate; Dogs; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Female; Male; Trichloroacetic Acid; Trichloroethylene; Urinary Bladder | 1988 |
Mechanistic studies on chloral toxicity: relationship to trichloroethylene carcinogenesis.
Topics: Acetaldehyde; Animals; Binding Sites; Cell Nucleus; Chloral Hydrate; Cross-Linking Reagents; DNA; DNA Damage; DNA, Single-Stranded; Drug Synergism; Liver; Male; Mice; Neoplasms; Rats; Rats, Inbred F344; Trichloroethylene | 1988 |
Determination of trichloroethylene metabolites in rat liver homogenate using headspace gas chromatography.
Topics: Animals; Chloral Hydrate; Chromatography, Gas; Decarboxylation; Hydrogen-Ion Concentration; Liver; Male; Rats; Rats, Inbred Strains; Trichloroethylene | 1988 |
The cholecystohepatic circulation of trichloroethylene and its metabolites in dogs.
Topics: Absorption; Animals; Bile; Chloral Hydrate; Dogs; Ethylene Chlorohydrin; Female; Gallbladder; Inactivation, Metabolic; Liver; Male; Trichloroacetic Acid; Trichloroethylene | 1987 |
The metabolism of trichloroethylene and its metabolites in the perfused liver.
Topics: Animals; Bile; Chloral Hydrate; Ethylene Chlorohydrin; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trichloroacetic Acid; Trichloroethylene | 1987 |
Mutagenicity of trichloroethylene, trichloroethanol and chloral hydrate in Aspergillus nidulans.
Topics: Aspergillus nidulans; Chloral Hydrate; Chlorohydrins; Crossing Over, Genetic; Ethylene Chlorohydrin; Genes, Fungal; Mitosis; Mutagenicity Tests; Trichloroethylene | 1985 |
Proceedings: Metabolization of trichloroethylene and its metabolites in rat liver.
Topics: Animals; Bile; Chloral Hydrate; Ethanol; Glucuronates; In Vitro Techniques; Liver; Oxidation-Reduction; Perfusion; Rats; Trichloroacetic Acid; Trichloroethylene | 1974 |
Some electrophysiological methods for studying the action of narcotic agents in animals, with special reference to industrial solvents: a review.
Topics: Animals; Cerebral Cortex; Chloral Hydrate; Electrocardiography; Electroencephalography; Electrophysiology; Ethanol; Guinea Pigs; Injections, Intraperitoneal; Narcotics; Rabbits; Reflex; Solvents; Synaptic Transmission; Trichloroethylene | 1968 |
Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction.
Topics: Animals; Chloral Hydrate; Chloromercuribenzoates; Cyanides; Dogs; Enzymes; Ethylmaleimide; Flavin Mononucleotide; Freeze Drying; In Vitro Techniques; Iodoacetates; Ions; Liver; Methylene Blue; Microsomes; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Trichloroethylene; Vitamin K | 1965 |
Metabolism of trichloroethylene in man. II. Pharmacokinetics of metabolites.
Topics: Adult; Chloral Hydrate; Environmental Exposure; Ethanol; Half-Life; Humans; Hydrocarbons, Chlorinated; Kinetics; Male; Respiration; Trichloroacetic Acid; Trichloroethylene | 1974 |
Metabolism of trichloroethylene in man. I. The significance of trichloroethanol in long-term exposure conditions.
Topics: Administration, Oral; Adult; Chloral Hydrate; Chlorine; Chromatography, Gas; Colorimetry; Environmental Exposure; Ethanol; Half-Life; Humans; Male; Neurocognitive Disorders; Respiration; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1972 |
Metabolism, excretion and toxicology of trichloroethylene after inhalation. 1. Experimental exposure on rats.
Topics: Air; Animals; Chloral Hydrate; Ethanol; Hydrocarbons, Halogenated; Liver; Male; Methods; Organ Size; Rats; Trichloroacetic Acid; Trichloroethylene | 1973 |
Metabolism, excretion and toxicology of trichloroethylene after inhalation. 2. Experimental human exposure.
Topics: Adult; Air; Chloral Hydrate; Ethanol; Female; Humans; Hydrocarbons, Halogenated; Male; Middle Aged; Respiration; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1973 |
Measurement of chloral hydrate, trichloroethanol, trichloroacetic acid and monochloroacetic acid in the serum and the urine by gas chromatography.
Topics: Acetates; Animals; Chloral Hydrate; Chromatography, Gas; Ethanol; Hydrocarbons, Chlorinated; Methods; Rabbits; Trichloroacetic Acid; Trichloroethylene | 1974 |
Metabolism of pentachloroethane in the mouse.
Topics: Animals; Chloral Hydrate; Chromatography, Gas; Chromatography, Paper; Ethanol; Female; Hydrocarbons, Halogenated; Mice; Mice, Inbred Strains; Spectrum Analysis; Tetrachloroethylene; Time Factors; Trichloroacetic Acid; Trichloroethylene | 1971 |
Metabolism of trichloroethylene in liver microsomes. II. Identification of the reaction product as chloral hydrate.
Topics: Acetates; Alcohol Oxidoreductases; Animals; Chloral Hydrate; Chromatography, Gas; Colorimetry; Cyanides; Dinitrophenols; Ethanol; In Vitro Techniques; Infrared Rays; Liver; Microsomes; Phenylhydrazines; Phloroglucinol; Spectrophotometry; Trichloroethylene | 1965 |
Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene.
Topics: Animals; Chloral Hydrate; Dose-Response Relationship, Drug; Male; Metaphase; Mice; Mice, Inbred Strains; Nondisjunction, Genetic; Ploidies; Spermatocytes; Spermatogenesis; Trichloroethylene | 1984 |
[Induction of sister chromatide exchange by trichloroethylene and its metabolites (author's transl)].
Topics: Chloral Hydrate; Chlorohydrins; Crossing Over, Genetic; Ethylene Chlorohydrin; Humans; In Vitro Techniques; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Trichloroethylene | 1981 |
Epinephrine-induced cardiac arrhythmias in rabbits exposed to trichloroethylene: role of trichloroethylene metabolites.
Topics: Animals; Arrhythmias, Cardiac; Biotransformation; Chloral Hydrate; Drug Interactions; Epinephrine; Male; Rabbits; Time Factors; Trichloroethylene | 1981 |
Metabolism of trichloroethylene.
Topics: Animals; Chloral Hydrate; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Proteins; Rats; Subcellular Fractions; Trichloroacetic Acid; Trichloroethylene | 1980 |
Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture.
Topics: Animals; Chloral Hydrate; Chloroacetates; Culture Techniques; Dichloroacetic Acid; Embryo, Mammalian; Embryonic and Fetal Development; Liver; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 1995 |
Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species.
Topics: Administration, Inhalation; Animals; Blotting, Western; Cell Division; Chloral Hydrate; Cytochrome P-450 CYP2E1; Ethylene Chlorohydrin; Female; Glucuronates; Humans; Immunoenzyme Techniques; In Vitro Techniques; Lung; Lung Neoplasms; Male; Mice; Microsomes; Microsomes, Liver; Rats; Rats, Wistar; Solvents; Species Specificity; Trichloroethylene | 1997 |
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Topics: Administration, Oral; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Feces; Glucuronates; Liver; Male; Mice; Mice, Inbred Strains; Models, Biological; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1997 |
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene | 1998 |
Cardiac teratogenicity of trichloroethylene metabolites.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Acetates; Animals; Chloral Hydrate; Cystine; Dichloroethylenes; Embryonic and Fetal Development; Environmental Pollutants; Ethylene Chlorohydrin; Female; Heart; Heart Defects, Congenital; Humans; Maternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Teratogens; Trichloroacetic Acid; Trichloroethylene; Water Pollutants, Chemical; Water Supply | 1998 |
Effect of ethanol on the metabolism of trichloroethylene in the perfused rat liver.
Topics: Animals; Biotransformation; Chloral Hydrate; Drug Administration Schedule; Ethanol; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Perfusion; Rats; Rats, Wistar; Trichloroethylene | 1998 |
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
Topics: Animals; Biological Availability; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Half-Life; Male; Metabolic Clearance Rate; Mice; Models, Biological; Trichloroacetic Acid; Trichloroethylene | 1998 |
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Topics: Adipose Tissue; Administration, Inhalation; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Kidney; Liver; Lung; Male; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Models, Biological; Oxidation-Reduction; Sensitivity and Specificity; Solvents; Tissue Distribution; Trichloroacetic Acid; Trichloroethylene | 1999 |
Trichloroethylene inhibits aldehyde dehydrogenase only for aliphatic aldehydes of short chains in rats.
Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehydes; Animals; Cell Fractionation; Chloral Hydrate; Cytochrome P-450 CYP2E1; Cytosol; Drug Combinations; Drug Interactions; Male; Methanol; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Solvents; Trichloroethylene | 1999 |
Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
Topics: Adult; Aged; Aminooxyacetic Acid; Chloral Hydrate; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Glutathione; Humans; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Male; Metyrapone; Microsomes; Middle Aged; Trichloroethylene | 2000 |
Cytochrome p450-dependent metabolism of trichloroethylene in rat kidney.
Topics: Animals; Blotting, Western; Chloral Hydrate; Chlorzoxazone; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Microsomes, Liver; Proadifen; Pyridines; Rats; Rats, Inbred F344; Trichloroethylene | 2001 |
Metabolism and toxicity of trichloroethylene in epididymis and testis.
Topics: Administration, Inhalation; Animals; Blotting, Western; Chloral Hydrate; Cytochrome P-450 CYP2E1; Epididymis; Ethylene Chlorohydrin; Immunohistochemistry; Male; Mice; Microsomes; Occupational Exposure; Testis; Trichloroacetic Acid; Trichloroethylene | 2002 |
Guinea pig maximization test for trichloroethylene and its metabolites.
Topics: Allergens; Animals; Chloral Hydrate; Dermatitis, Allergic Contact; Dermatitis, Irritant; Ethylene Chlorohydrin; Guinea Pigs; Skin; Toxicity Tests; Trichloroacetic Acid; Trichloroethylene | 2002 |
Further studies on the metabolic fate of chloral hydrate and trichloroethanol.
Topics: Biochemical Phenomena; Blood; Chloral Hydrate; Ethanol; Ethylene Chlorohydrin; Humans; Trichloroacetic Acid; Trichloroethylene | 1955 |
ANAESTHESIA AND ANALGESIA IN DOMICILIARY MIDWIFERY.
Topics: Analgesia; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Obstetrical; Chloral Hydrate; Chlorpromazine; Female; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Meperidine; Midwifery; Morphine; Nalorphine; Nitrous Oxide; Pain; Pentobarbital; Pregnancy; Secobarbital; Toxicology; Trichloroethylene | 1964 |
Environmental contaminant and disinfection by-product trichloroacetaldehyde stimulates T cells in vitro.
Topics: Animals; Autoimmunity; Blotting, Western; CD28 Antigens; Cell Proliferation; Chloral Hydrate; Disinfectants; Environmental Pollutants; Female; L-Selectin; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Schiff Bases; T-Lymphocytes; Th1 Cells; Trichloroethylene | 2004 |
Exposure to trichloroethylene and its metabolites causes impairment of sperm fertilizing ability in mice.
Topics: Acrosome Reaction; Anesthetics, Intravenous; Animals; Body Weight; Chloral Hydrate; Epididymis; Ethylene Chlorohydrin; Female; Fertilization; Fertilization in Vitro; In Vitro Techniques; Inhalation Exposure; Male; Mice; Organ Size; Solvents; Sperm Count; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Testis; Trichloroethylene | 2004 |
Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1.
Topics: Animals; Biotransformation; Chloral Hydrate; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Humans; Lung; Male; Mice; Mice, Inbred Strains; Microsomes; Rats; Recombinant Proteins; Trichloroethylene | 2005 |
Application of cryopreserved human hepatocytes in trichloroethylene risk assessment: relative disposition of chloral hydrate to trichloroacetate and trichloroethanol.
Topics: Adult; Aged; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Chloral Hydrate; Cryopreservation; Ethylene Chlorohydrin; Female; Genotype; Hepatocytes; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Risk Assessment; Solvents; Trichloroacetic Acid; Trichloroethylene | 2006 |
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Topics: Animals; Bayes Theorem; Chloral Hydrate; Dichloroacetic Acid; Dose-Response Relationship, Drug; Ethylene Chlorohydrin; Humans; Kinetics; Markov Chains; Mice; Models, Biological; Monte Carlo Method; Rats; Sulfhydryl Compounds; Trichloroacetic Acid; Trichloroethylene | 2006 |
Chronic exposure to a trichloroethylene metabolite in autoimmune-prone MRL+/+ mice promotes immune modulation and alopecia.
Topics: Administration, Oral; Alopecia; Animals; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Chloral Hydrate; Dermatitis; Dose-Response Relationship, Drug; Environmental Pollutants; Fas Ligand Protein; Female; Interferon-gamma; Lymph Nodes; Matrix Metalloproteinase 7; Mice; Mice, Inbred MRL lpr; Spleen; Time Factors; Trichloroethylene | 2007 |
TRICHLOROETHYLENE, TETRACHLOROETHYLENE, AND SOME OTHER CHLORINATED AGENTS.
Topics: Animals; Carcinogenicity Tests; Carcinogens, Environmental; Chloral Hydrate; Dichloroacetic Acid; Ethane; Humans; Hydrocarbons, Chlorinated; Neoplasms; Risk Assessment; Tetrachloroethylene; Trichloroacetic Acid; Trichloroethylene | 2014 |