chitosan has been researched along with verapamil in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 14 (60.87) | 24.3611 |
| 2020's | 4 (17.39) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffer, M; Werle, M | 1 |
| Bouropoulos, N; Pasparakis, G | 1 |
| Bruesewitz, C; Funke, A; Kuhland, U; Lipp, R; Wagner, T | 1 |
| Bernkop-Schnürch, A; Hombach, J; Hoyer, H | 1 |
| Dharmala, K; Lee, CH; Yoo, JW | 1 |
| Ansari, MT; Ayub, G; Naseem, S; Ranjha, NM | 1 |
| Mo, R; Ping, Q; Sun, M; Xiao, Y; Zhang, C | 1 |
| Bernkop-Schnürch, A; Iqbal, J; Sakloetsakun, D | 1 |
| Jin, X; Ju, C; Li, N; Mo, R; Ping, Q; Sun, M; Zhang, C | 1 |
| Chen, Y; Duan, C; Hao, L; Jia, L; Liu, G; Liu, Y; Wang, F; Zhang, D; Zhang, Q; Zheng, D | 1 |
| Abdel Mouez, M; Geneidi, AS; Mansour, S; Zaki, NM | 1 |
| Abdel-Mottaleb, M; Geneidi, AS; Mansour, S; Mouez, MA; Nasr, M | 1 |
| Fereira, N; Godfrey, L; Odunze, U; Sasaki, K; Schätzlein, A; Soundararajan, R; Uchegbu, I | 1 |
| Asghar, S; Chen, Z; Gao, S; Huang, L; Ping, Q; Xiao, Y; Xu, Y; Yin, L | 1 |
| Chen, Q; Fu, Y; Huo, M; Li, L; Liu, Y; Mu, Y; Xu, W; Yin, T; Zhou, J | 1 |
| Ashrafi, H; Azadi, A; Moghaddam Panah, F; Pourtalebi Jahromi, L | 1 |
| Chu, K; Guo, Y; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W | 1 |
| Hou, S; Ju, C; Qu, D; Qu, G; Tian, C; Xue, L; Zhang, C; Zhu, J | 1 |
| Aleksandrov, HA; Konstantinov, S; Koseva, N; Lazarova, H; Mihályi, J; Mihaylova, R; Mitova, V; Momekov, G; Momekova, D; Popova, M; Shestakova, P; St Petkov, P; Szegedi, Á; Trendafilova, I; Vayssilov, GN | 1 |
| Chu, K; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W; Zhang, X | 1 |
| Abo Mansour, HE; Abo-Elmatty, DM; Badawy, NS; El-Batsh, MM; Mehanna, ET; Mesbah, NM | 1 |
| Pham, TPT; Song, MH; Yun, YS | 1 |
| Dong, Z; Liu, F; Sun, J; Xue, L; Younas, A; Zhang, N; Zhao, Y | 1 |
23 other study(ies) available for chitosan and verapamil
| Article | Year |
|---|---|
Glutathione and thiolated chitosan inhibit multidrug resistance P-glycoprotein activity in excised small intestine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Chitosan; Dose-Response Relationship, Drug; Electric Impedance; Glutathione; Guinea Pigs; Ileum; In Vitro Techniques; Reproducibility of Results; Rhodamine 123; Sulfhydryl Compounds; Terfenadine; Verapamil | 2006 |
Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads.
Topics: Alginates; Anti-Arrhythmia Agents; Buffers; Chitosan; Delayed-Action Preparations; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Hydrochloric Acid; Microscopy, Electron, Scanning; Particle Size; Spectroscopy, Fourier Transform Infrared; Verapamil; Water | 2006 |
Comparison of permeation enhancing strategies for an oral factor Xa inhibitor using the Caco-2 cell monolayer model.
Topics: Algorithms; Antithrombin III; Caco-2 Cells; Cell Membrane Permeability; Chitosan; Drug Synergism; Glycerides; Humans; Molecular Structure; Probenecid; Prodrugs; Quinidine; Serine Proteinase Inhibitors; Spectrophotometry, Ultraviolet; Verapamil | 2006 |
Thiolated chitosans: development and in vitro evaluation of an oral tobramycin sulphate delivery system.
Topics: Acetylcysteine; Administration, Oral; Animals; Biological Transport; Caco-2 Cells; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Epithelial Cells; Glutathione; Humans; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tablets; Technology, Pharmaceutical; Tobramycin; Verapamil | 2008 |
Development of chitosan-SLN microparticles for chemotherapy: in vitro approach through efflux-transporter modulation.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Biological Transport; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Therapy; Isothiocyanates; Lipids; Nanoparticles; Nifedipine; Particle Size; Tamoxifen; Verapamil | 2008 |
Preparation and characterization of hybrid pH-sensitive hydrogels of chitosan-co-acrylic acid for controlled release of verapamil.
Topics: Acrylates; Biocompatible Materials; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; In Vitro Techniques; Materials Testing; Microscopy, Electron, Scanning; Molecular Weight; Porosity; Spectroscopy, Fourier Transform Infrared; Static Electricity; Verapamil | 2010 |
Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Chitosan; Etoposide; Excipients; Humans; Intestinal Absorption; Micelles; Rats; Rats, Sprague-Dawley; Solubility; Verapamil | 2011 |
Thiomers: Inhibition of cytochrome P450 activity.
Topics: Aryl Hydrocarbon Hydroxylases; Chitosan; Coumarins; Cysteine; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Carriers; Drug Compounding; Drug Delivery Systems; Enzyme Assays; Enzyme Inhibitors; Excipients; Indicators and Reagents; Polymers; Sulfhydryl Compounds; Verapamil | 2011 |
The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles.
Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Biological Availability; Caco-2 Cells; Calcium Channel Blockers; Chitosan; Endocytosis; Humans; Materials Testing; Micelles; Paclitaxel; Rats; Rats, Sprague-Dawley; Verapamil | 2011 |
Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Chitosan; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; Fluorescence; Folic Acid; Humans; Inhibitory Concentration 50; Micelles; Microscopy, Electron, Scanning; Paclitaxel; Particle Size; Polymers; Verapamil; X-Ray Diffraction | 2011 |
Bioavailability enhancement of verapamil HCl via intranasal chitosan microspheres.
Topics: Adhesiveness; Administration, Intranasal; Animals; Biological Availability; Chitosan; Male; Microspheres; Nasal Mucosa; Particle Size; Rabbits; Verapamil | 2014 |
Composite chitosan-transfersomal vesicles for improved transnasal permeation and bioavailability of verapamil.
Topics: Administration, Intranasal; Animals; Biological Availability; Chitosan; Drug Compounding; Drug Stability; Elasticity; Hydrogen-Ion Concentration; Liposomes; Male; Nasal Mucosa; Particle Size; Permeability; Rabbits; Sheep; Verapamil | 2016 |
Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Chitosan; Drug Carriers; Epithelial Cells; Humans; Ileum; Intestinal Absorption; Male; Mice; Nanoparticles; Paclitaxel; Rats; Rats, Wistar; Solubility; Tight Junctions; Verapamil; Water | 2016 |
Polysaccharide-based nanoparticles for co-loading mitoxantrone and verapamil to overcome multidrug resistance in breast tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mitoxantrone; Nanoparticles; Polyelectrolytes; Verapamil | 2017 |
N-mercapto acetyl-N'-octyl-O, N″-glycol chitosan as an efficiency oral delivery system of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Chitosan; Drug Carriers; Endocytosis; Humans; Intestinal Mucosa; Micelles; Paclitaxel; Particle Size; Rats, Sprague-Dawley; Tight Junctions; Verapamil | 2018 |
A mechanistic investigation on methotrexate-loaded chitosan-based hydrogel nanoparticles intended for CNS drug delivery: Trojan horse effect or not?
Topics: Animals; Brain; Chitosan; Drug Carriers; Drug Delivery Systems; Hydrogels; Methotrexate; Nanoparticles; Particle Size; Rats; Verapamil | 2019 |
Preparation and evaluation of carboxymethyl chitosan-rhein polymeric micelles with synergistic antitumor effect for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Drug Synergism; Humans; Male; Mice, Inbred ICR; Micelles; Neoplasms; Paclitaxel; Verapamil | 2019 |
Self-assembled micelles based on N-octyl-N'-phthalyl-O-phosphoryl chitosan derivative as an effective oral carrier of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Down-Regulation; Drug Carriers; Drug Liberation; Endocytosis; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Fluidity; Mice, Inbred BALB C; Micelles; Paclitaxel; Rats, Sprague-Dawley; Solubility; Transcytosis; Verapamil | 2019 |
Verapamil delivery systems on the basis of mesoporous ZSM-5/KIT-6 and ZSM-5/SBA-15 polymer nanocomposites as a potential tool to overcome MDR in cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Resistance, Multiple; HL-60 Cells; HT29 Cells; Humans; Hydrogen-Ion Concentration; Nanocomposites; Nanoparticles; Polymers; Porosity; Silicon Dioxide; Verapamil | 2019 |
Evaluation of intestinal permeation enhancement with carboxymethyl chitosan-rhein polymeric micelles for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Intestinal Mucosa; Male; Mice; Micelles; Neoplasms; Paclitaxel; Permeability; Rats; Tissue Distribution; Verapamil | 2020 |
Effect of co-treatment with doxorubicin and verapamil loaded into chitosan nanoparticles on diethylnitrosamine-induced hepatocellular carcinoma in mice.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cardiotoxicity; Cell Survival; Chitosan; Diethylnitrosamine; Doxorubicin; Drug Combinations; Drug Delivery Systems; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Malondialdehyde; Mice; Myocardium; Nanoparticles; Proto-Oncogene Proteins c-bcl-2; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Verapamil | 2020 |
Ionic liquid-assisted cellulose coating of chitosan hydrogel beads and their application as drug carriers.
Topics: Cellulose; Chitosan; Drug Carriers; Drug Liberation; Hydrogels; Ionic Liquids; Microspheres; Spectroscopy, Fourier Transform Infrared; Verapamil; X-Ray Diffraction | 2020 |
Co-delivery of triamcinolone acetonide and verapamil for synergistic treatment of hypertrophic scars via carboxymethyl chitosan and Bletilla striata polysaccharide-based microneedles.
Topics: Chitosan; Cicatrix, Hypertrophic; Humans; Polysaccharides; Triamcinolone Acetonide; Verapamil | 2022 |