chitosan has been researched along with simvastatin in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 18 (56.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chiono, V; Ciardelli, G; Daly, J; Gentile, P; Mattu, C; Nandagiri, VK; Ramtoola, Z; Tonda-Turo, C | 1 |
| Koumaravelou, K; Selvasudha, N | 1 |
| Fu, X; Guo, Q; Hai, B; Liu, C; Ma, T; Song, C; Tan, J; Wang, H; Xu, Y; Zhang, W | 1 |
| Baradaran, A; Minaiyan, M; Rastegarnasab, F; Taymouri, S; Varshosaz, J | 1 |
| Li, Y; Zhang, Z | 1 |
| Clementino, A; Sonvico, F | 1 |
| Anovazzi, G; Basso, FG; Bordini, EAF; de Souza Costa, CA; Hebling, J; Silva Leite, MLA; Soares, DG; Zuta, UO | 1 |
| Jin, Z; Lai, M; Yan, X | 1 |
| Sun, D; Wang, Y; Yuan, X; Zhang, M; Zhao, H | 1 |
| Boccaccini, AR; Chen, Q; Cui, N; Dong, R; Heise, S; Lu, T; Qi, H; Schuhladen, K; Virtanen, S; Yang, Y; Zhou, J | 1 |
| Chen, F; Guan, B; Jin, C; Jin, L; Li, H; Li, Y; Lin, M; Liu, D; Liu, Z; Luo, S; Song, J; Wu, M; Xue, Y; Zhang, X | 1 |
| Barone, A; Cabral, C; Mare, R; Mendes, M; Paolino, D; Vitorino, C | 1 |
| Chen, J; Chen, S; Ding, X; Jin, W; Liu, X; Wang, S | 1 |
| Koumaravelou, K; Sarathchandiran, I; Selvasudha, N | 1 |
| Azadi, A; Azadi, S; Farjadian, F; Mohammadi Samani, S; Mozafari, N | 1 |
| Delan, WK; ElMeshad, AN; Elsaadany, B; Fares, AR; Mamdouh, W; Zakaria, M | 1 |
| Blanchemain, N; Cazaux, F; Chai, F; Degoutin, S; Janus, L; Kersani, D; Lopez, M; Martel, B; Maton, M; Mougin, J; Sobocinski, J; Tabary, N | 1 |
| Kurakula, M; Naveen, NR | 1 |
| Abdel-Naim, AB; Abdulaal, WH; Ahmed, OAA; Aldawsari, HM; Alhakamy, NA; Asfour, HZ; Bakhrebah, MA; Caraci, F; Caruso, G; Eid, BG; Fahmy, UA; Kurakula, M; Mohamed, AI; N Alomary, M; Okbazghi, SZ | 1 |
| Atwill, MT; Bumgardner, JD; Fujiwara, T; Gallop, C; Kurakula, M; Murali, VP; Wang, Y; Wilson, JA | 1 |
| Anovazzi, G; Bordini, EAF; Cassiano, FB; Costa, CAS; Hebling, J; Soares, DG | 1 |
| Chakravarthi, S; Fuloria, S; Hari Kumar, D; Kumar Fuloria, N; Kumari, U; Malviya, R; Porwal, O; Raj, S; Sathasivam, K; Singh, A; Subramaniyan, V; Unnikrishnan Meenakshi, D | 1 |
| Bumgardner, JD; Christian, JM; Ghadri, N; Guerra, FD; Jennings, JA; Murali, VP; Smith, RA; Stein, SH | 1 |
| Bumgardner, JD; Chowdhury, N; Cisneros, K; Coleman, E; Ferdous, T; Fujiwara, T; Jennings, JA; Su, H | 1 |
| Banella, S; Cantù, L; Clementino, AR; Colombo, G; Del Favero, E; Pellegrini, G; Sonvico, F | 1 |
| Katas, H; Omer, MO; Rasool, F; Sarfraz, M; Shahid, MN; Siddique, MI; Sohail, MF; Tufail, S | 1 |
| Almeida, JM; Bordini, EAF; Bronze-Uhle, ES; Cassiano, FB; Cintra, LTA; de Souza Costa, CA; Gallinari, MO; Hebling, J; Matheus, HR; Silva, ISP; Soares, DG | 1 |
| Boccaccini, AR; Dong, K; Heise, S; Li, M; Lu, T; Qi, H; Wang, K; Zhang, Y | 1 |
| Bruinsmann, FA; de Cristo Soares Alves, A; de Fraga Dias, A; Figueiró, F; Lopes Silva, LF; Raffin Pohlmann, A; Sonvico, F; Stanisçuaski Guterres, S; Visioli, F | 1 |
| Ali, IH; Delan, WK; ElMeshad, AN; Elsaadany, B; Fares, AR; Mamdouh, W; Zakaria, M | 1 |
| Karami, F; Saber-Samandari, S | 1 |
| Almeida, JM; Bordini, EAF; Cassiano, FB; Cintra, LTÂ; DE Souza Costa, CA; Gallinari, MO; Melo, CCDSB; Soares, DG; Stuani, VT | 1 |
32 other study(ies) available for chitosan and simvastatin
| Article | Year |
|---|---|
Localised controlled release of simvastatin from porous chitosan-gelatin scaffolds engrafted with simvastatin loaded PLGA-microparticles for bone tissue engineering application.
Topics: Cell Line; Chitosan; Gelatin; Humans; Materials Testing; Osteoblasts; Porosity; Simvastatin; Tissue Engineering; Tissue Scaffolds | 2016 |
The multifunctional synergistic effect of chitosan on simvastatin loaded nanoparticulate drug delivery system.
Topics: Animals; Chitosan; Drug Delivery Systems; Drug Liberation; Drug Synergism; Female; Hypolipidemic Agents; Lipids; Mice; Particle Size; Simvastatin; Solubility | 2017 |
Chitosan conduits filled with simvastatin/Pluronic F-127 hydrogel promote peripheral nerve regeneration in rats.
Topics: Animals; Chitosan; Hydrogels; Male; Nerve Regeneration; Poloxamer; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Simvastatin | 2018 |
Development and in vitro/in vivo evaluation of HPMC/chitosan gel containing simvastatin loaded self-assembled nanomicelles as a potent wound healing agent.
Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Drug Carriers; Drug Liberation; Gels; Hypromellose Derivatives; Male; Micelles; Nanoparticles; Particle Size; Poloxamer; Polyethylene Glycols; Rats; Rats, Wistar; Rheology; Simvastatin; Surface Properties; Wound Healing | 2018 |
Porous Chitosan/Nano-Hydroxyapatite Composite Scaffolds Incorporating Simvastatin-Loaded PLGA Microspheres for Bone Repair.
Topics: Animals; Bone and Bones; Bone Regeneration; Calcium; Cell Proliferation; Cells, Cultured; Chitosan; Compressive Strength; Drug Liberation; Durapatite; Gene Expression Regulation; Imaging, Three-Dimensional; Male; Mesenchymal Stem Cells; Microspheres; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats, Wistar; Simvastatin; Skull; Tissue Scaffolds; Wound Healing; X-Ray Microtomography | 2018 |
Development and validation of a RP-HPLC method for the simultaneous detection and quantification of simvastatin's isoforms and coenzyme Q10 in lecithin/chitosan nanoparticles.
Topics: Chitosan; Chromatography, High Pressure Liquid; Drug Delivery Systems; Kinetics; Lecithins; Nanocapsules; Nanoparticles; Protein Isoforms; Simvastatin; Spectrophotometry, Ultraviolet; Ubiquinone | 2018 |
Biological Analysis of Simvastatin-releasing Chitosan Scaffold as a Cell-free System for Pulp-dentin Regeneration.
Topics: Cell-Free System; Cells, Cultured; Chitosan; Dental Pulp; Dentin; Dose-Response Relationship, Drug; Humans; Male; Regeneration; Regenerative Endodontics; Simvastatin; Tissue Engineering; Tissue Scaffolds; Young Adult | 2018 |
The response of bone cells to titanium surfaces modified by simvastatin-loaded multilayered films.
Topics: Animals; Calcification, Physiologic; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Chitosan; Coated Materials, Biocompatible; Drug Carriers; Drug Liberation; Gelatin; Membranes, Artificial; Mesenchymal Stem Cells; Mice; Osteoblasts; Osteoclasts; Rats, Wistar; RAW 264.7 Cells; Simvastatin; Surface Properties; Tissue Scaffolds; Titanium | 2018 |
Using co-axial electrospray deposition to eliminate burst release of simvastatin from microparticles and to enhance induced osteogenesis.
Topics: Animals; Biocompatible Materials; Cell Differentiation; Cell Proliferation; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Durapatite; Electricity; Mesenchymal Stem Cells; Microspheres; Nanostructures; Osteogenesis; Rats; Rats, Sprague-Dawley; Simvastatin; Zein | 2019 |
Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair.
Topics: Alloys; Animals; Bone Regeneration; Cell Differentiation; Cell Line; Cell Survival; Chitosan; Coated Materials, Biocompatible; Core Binding Factor Alpha 1 Subunit; Drug Carriers; Extracellular Matrix; Gelatin; Magnesium; Mice; Osteoblasts; Osteogenesis; Polymers; Simvastatin | 2019 |
In vitro and in vivo evaluation of chitosan scaffolds combined with simvastatin-loaded nanoparticles for guided bone regeneration.
Topics: Animals; Bone and Bones; Bone Regeneration; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chitosan; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Guided Tissue Regeneration; Male; Materials Testing; Microspheres; Nanoparticles; Osteogenesis; Rats; Rats, Sprague-Dawley; Simvastatin; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2019 |
Hybrid Nanostructured Films for Topical Administration of Simvastatin as Coadjuvant Treatment of Melanoma.
Topics: Adhesives; Administration, Topical; Animals; Cell Line; Chitosan; Chlorocebus aethiops; COS Cells; Drug Carriers; Drug Liberation; Humans; Lipids; Melanoma; Melanoma, Cutaneous Malignant; Nanoparticles; Nanostructures; Particle Size; Permeability; Simvastatin; Skin; Skin Absorption; Skin Neoplasms | 2019 |
Encapsulation of a nanoporous simvastatin-chitosan composite to enhance osteointegration of hydroxyapatite-coated polyethylene terephthalate ligaments.
Topics: Animals; Bone and Bones; Cell Differentiation; Cell Line; Cell Proliferation; Chitosan; Drug Liberation; Durapatite; Ligaments; Male; Nanopores; Osseointegration; Osteocalcin; Osteogenesis; Polyethylene Terephthalates; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; X-Ray Microtomography | 2019 |
Interaction pattern and
Topics: Administration, Oral; Animals; Chitosan; Cholesterol, Dietary; Delayed-Action Preparations; Disease Models, Animal; Drug Administration Schedule; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hyperlipidemias; Mice; Molecular Docking Simulation; Nanoparticles; Particle Size; Proton Magnetic Resonance Spectroscopy; Simvastatin; Spectroscopy, Fourier Transform Infrared | 2019 |
Simvastatin-chitosan-citicoline conjugates nanoparticles as the co-delivery system in Alzheimer susceptible patients.
Topics: Alzheimer Disease; Chitosan; Cytidine Diphosphate Choline; Disease Susceptibility; Drug Carriers; Humans; Nanoparticles; Simvastatin | 2020 |
Formulation of simvastatin chitosan nanoparticles for controlled delivery in bone regeneration: Optimization using Box-Behnken design, stability and in vivo study.
Topics: Administration, Oral; Animals; Biological Availability; Bone Density; Bone Regeneration; Chitosan; Cone-Beam Computed Tomography; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Male; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Rabbits; Simvastatin; Surface Properties | 2020 |
Stent coating by electrospinning with chitosan/poly-cyclodextrin based nanofibers loaded with simvastatin for restenosis prevention.
Topics: Alloys; Angioplasty; beta-Cyclodextrins; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Drug-Eluting Stents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Models, Chemical; Nanofibers; Prosthesis Design; Self Expandable Metallic Stents; Simvastatin; Solubility; Surface Properties | 2020 |
In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma.
Topics: Carcinoma; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Mouth Neoplasms; Nanoparticles; Particle Size; Simvastatin; Tongue | 2020 |
Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Chitosan; Colonic Neoplasms; Drug Carriers; Drug Delivery Systems; HCT116 Cells; Humans; Hydrogen-Ion Concentration; Male; Microspheres; Particle Size; Polymethacrylic Acids; Rabbits; Simvastatin | 2020 |
Modified electrospun chitosan membranes for controlled release of simvastatin.
Topics: Acylation; Animals; Cell Line; Cell Survival; Chitosan; Delayed-Action Preparations; Fatty Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membranes, Artificial; Mice; Nanofibers; Simvastatin | 2020 |
Simvastatin-Enriched Macro-Porous Chitosan-Calcium-Aluminate Scaffold for Mineralized Tissue Regeneration.
Topics: Aluminum Compounds; Calcium; Calcium Compounds; Chitosan; Humans; Porosity; Simvastatin | 2020 |
Evaluation of Antitumor Efficacy of Chitosan-Tamarind Gum Polysaccharide Polyelectrolyte Complex Stabilized Nanoparticles of Simvastatin.
Topics: Antineoplastic Agents; Cell Death; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; MCF-7 Cells; Nanoparticles; Particle Size; Plant Gums; Polyelectrolytes; Polysaccharides; Simvastatin; Spectrophotometry, Infrared; Static Electricity; Tamarindus | 2021 |
Simvastatin loaded chitosan guided bone regeneration membranes stimulate bone healing.
Topics: Animals; Bone Regeneration; Chitosan; Membranes, Artificial; Osteogenesis; Rats; Simvastatin | 2021 |
Long-Term Controlled Release of Simvastatin from Photoprinted Triple-Networked Hydrogels Composed of Modified Chitosan and PLA-PEG Micelles.
Topics: Chitosan; Delayed-Action Preparations; Hydrogels; Micelles; Polyesters; Polyethylene Glycols; Simvastatin | 2021 |
Structure and Fate of Nanoparticles Designed for the Nasal Delivery of Poorly Soluble Drugs.
Topics: Administration, Intranasal; Animals; Biocompatible Materials; Biological Transport; Caproates; Cell Line; Cell Survival; Chitosan; Drug Liberation; Humans; Hyaluronic Acid; Lactones; Lecithins; Nanocapsules; Nanoparticle Drug Delivery System; Nasal Mucosa; Particle Size; Polysorbates; Rabbits; Simvastatin; Solubility; Surface-Active Agents; Swine | 2021 |
Simvastatin Nanoparticles Loaded Polymeric Film as a Potential Strategy for Diabetic Wound Healing: In Vitro and In Vivo Evaluation.
Topics: Animals; Chitosan; Diabetes Mellitus; Nanoparticles; Polymers; Rats; Simvastatin; Wound Healing | 2022 |
Chitosan-Calcium-Simvastatin Scaffold as an Inductive Cell-Free Platform.
Topics: Animals; Calcium; Cell Differentiation; Chitosan; Dental Pulp; Dentin; Odontoblasts; Rats; Simvastatin | 2021 |
Co-culture of BMSCs and HUVECs with simvastatin-loaded gelatin nanosphere/chitosan coating on Mg alloy for osteogenic differentiation and vasculogenesis.
Topics: Alloys; Angiogenesis Inducing Agents; Bone and Bones; Cell Differentiation; Cells, Cultured; Chitosan; Coculture Techniques; Gelatin; Human Umbilical Vein Endothelial Cells; Humans; Magnesium; Mesenchymal Stem Cells; Nanospheres; Osteogenesis; Simvastatin | 2021 |
Nose-to-brain delivery of simvastatin mediated by chitosan-coated lipid-core nanocapsules allows for the treatment of glioblastoma in vivo.
Topics: Administration, Intranasal; Animals; Brain; Cell Line, Tumor; Chitosan; Glioblastoma; Lipids; Nanocapsules; Rats; Simvastatin | 2022 |
Investigating the bone regeneration activity of PVA nanofibers scaffolds loaded with simvastatin/chitosan nanoparticles in an induced bone defect rabbit model.
Topics: Animals; Bone Regeneration; Chitosan; Nanofibers; Nanoparticles; Rabbits; Simvastatin; Tissue Scaffolds | 2022 |
Synthesis and characterization of a novel hydrogel based on carboxymethyl chitosan/sodium alginate with the ability to release simvastatin for chronic wound healing.
Topics: Alginates; Animals; Anti-Bacterial Agents; Chitosan; Hydrogels; Mice; Simvastatin; Wound Healing | 2023 |
Assessment of the regenerative potential of macro-porous chitosan-calcium simvastatin scaffolds on bone cells.
Topics: Calcium; Calcium Hydroxide; Cell Differentiation; Chitosan; Osteogenesis; Porosity; Simvastatin; Tissue Engineering; Tissue Scaffolds | 2023 |