chitosan has been researched along with paclitaxel in 206 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (0.49) | 18.2507 |
2000's | 34 (16.50) | 29.6817 |
2010's | 132 (64.08) | 24.3611 |
2020's | 39 (18.93) | 2.80 |
Authors | Studies |
---|---|
Ishibe, A; Itai, S; Jinno, S; Kawahara, H; Miwa, A; Nakano, M; Yamahira, T | 1 |
Berrada, M; Bichara, A; Chenite, A; Le Garrec, D; Leroux, JC; Ruel-Gariépy, E; Shive, M | 1 |
Burt, HM; Cruz, T; Hunter, WL; Liang, L; Liggins, RT; Min, W | 1 |
Qineng, P; Zhang, C; Zhang, H | 1 |
Bilodeau, L; Kujawa, P; Tabrizian, M; Thierry, B; Tkaczyk, C; Winnik, FM | 1 |
Dhanikula, AB; Panchagnula, R | 1 |
Burt, HM; Gleave, ME; Jackson, JK; Springate, CM | 1 |
Allen, C; Ho, EA; Piquette-Miller, M; Vassileva, V | 1 |
Allen, C; Blicker, M; Grant, J; Piquette-Miller, M | 1 |
Hattori, H; Hayashi, T; Ishihara, M; Ishizuka, T; Kikuchi, M; Maehara, T; Matsui, T; Nakamura, S; Obara, K; Ozeki, Y; Saito, Y; Takase, B; Yura, H | 1 |
Dhanikula, AB; Panchagnula, R; Singh, DR | 1 |
Choi, K; Chung, H; Jeong, SY; Kim, IS; Kim, JH; Kim, K; Kim, S; Kim, YS; Kwon, IC; Park, JH; Park, RW | 1 |
Fujita, M; Hattori, H; Ishihara, M; Kanatani, Y; Kikuchi, M; Maehara, T; Masuoka, K; Morimoto, Y; Nakamura, S; Obara, K; Takase, B | 1 |
Du, YZ; Hu, FQ; Ren, GF; Yuan, H; Zeng, S | 1 |
Dhanikula, AB; Dhanikula, RS; Panchagnula, R | 1 |
Cho, YW; Han, SS; Han, TH; Hwang, JJ; Kim, SY; Lee, KY; Moon, DH; Park, JS | 1 |
Fujita, M; Hattori, H; Ishihara, M; Kanatani, Y; Kikuchi, M; Kiyosawa, T; Maehara, T; Nakamura, S; Nambu, M; Obara, K; Takase, B | 1 |
Huo, MR; Lü, L; Wei, Y; Zhou, JP | 1 |
Allen, C; De Souza, R; Grant, J; Piquette-Miller, M; Vassileva, V | 1 |
Du, YZ; Hu, FQ; You, J; Yuan, H | 1 |
Ding, Q; Guo, Q; Ping, Q; Qu, G; Shen, Z; Sun, Y; Wu, X; Yao, Z; Yuan, S; Zhang, C; Zhou, H | 1 |
Allen, C; Cho, J; Grant, J; Ho, E; Lim Soo, P; Piquette-Miller, M | 1 |
Dash, AK; Nagvekar, AA; Trickler, WJ | 2 |
Cheng, G; Chung, SJ; Cui, F; Kim, DD; Kim, IW; Shim, CK; Shim, WS; Yang, R; Yang, SG | 1 |
Kim, BS; Kim, CS; Lee, KM | 1 |
Chae, SY; Jon, S; Kim, H; Lee, E; Lee, IH; Lee, J; Yu, M | 1 |
Huo, MR; Liu, FJ; Liu, H; Lü, L; Zhang, Y; Zhou, JP | 1 |
Cheng, G; Chung, SJ; Cui, FD; Han, X; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Yang, R | 1 |
Ding, S; Li, H; Liu, J; Shen, W; You, Q; Zhang, C | 1 |
Bao, J; He, M; Shi, L; Tang, C; Wang, B; Yin, C; Yin, L; Zhao, Z | 1 |
Li, M; Lu, S; Wang, Z; Yang, Y | 1 |
Ping, Q; Qu, G; Wu, X; Yao, Z; Zhang, C | 1 |
Cho, YW; Jeong, SY; Kim, AY; Kim, K; Kwon, IC; Lee, CM; Lee, SC; Min, DS; Min, KH; Park, JH; Park, K; Saravanakumar, G | 1 |
Gao, HX; Li, MJ; Wang, TW; Wu, Y | 1 |
Akhlaghi, SP; Atyabi, F; Dinarvand, R; Ostad, SN; Saremi, S | 1 |
Ghosh, SK; Maiti, S; Maiti, TK; Pramanik, P; Sahu, SK | 1 |
Choi, K; Kim, IS; Kim, JH; Kim, K; Kim, SY; Kim, YS; Kwon, IC; Lee, S; Nam, H; Park, H; Park, JH; Park, K; Park, RW | 1 |
Huo, M; Li, H; Li, J; Wu, Y; Yu, D; Zhang, Y; Zhou, J; Zou, A | 1 |
Cormack, R; Gultepe, E; Jost, E; Levy, CO; Makrigiorgos, GM; Nagesha, D; Singh, S; Sridhar, S; Tada, DB | 1 |
Cao, S; Chang, J; Niu, R; Wang, H; Yu, M; Zhang, F; Zhao, P | 1 |
Kim, S; Lee, J | 1 |
Jang, MK; Jeong, YI; Nah, JW | 1 |
Dai, Y; Deng, Y; Huo, M; Li, H; Masoud, J; Shi, X; Zhou, J | 1 |
Chen, D; Jin, X; Li, H; Liu, J; Ping, Q; Zhang, C; Zhao, X | 1 |
Chakravarthi, SS; Robinson, DH | 1 |
Li, J; Liu, C; Liu, F; Liu, J; Qu, X; Wang, Q; Yang, Z; Zhang, C; Zhao, L; Zhu, L | 1 |
Jin, X; Ju, C; Li, N; Mo, R; Ping, Q; Sun, M; Zhang, C | 1 |
Choa, YH; Jang, DH; Jung, HS; Kim, MJ; Lee, HJ; Lee, YI | 1 |
Khar, RK; Mishra, PR; Singodia, D; Talegaonkar, S | 1 |
Dash, AK; Jain, N; Joshi, SS; Munt, DJ; Trickler, WJ | 1 |
Chang, J; Li, A; Liang, S; Wang, H; Yan, R; Zhang, J; Zhao, M | 1 |
Pishko, MV; Yu, X | 1 |
Chen, Y; Duan, C; Hao, L; Jia, L; Liu, G; Liu, Y; Wang, F; Zhang, D; Zhang, Q; Zheng, D | 2 |
Bae, SM; Choi, KY; Hoffman, AS; Kim, IS; Kim, JH; Kim, K; Kwon, IC; Lee, BH; Min, KH; Na, MH; Park, RW; Shin, H; Yang, YJ | 1 |
Parveen, S; Sahoo, SK | 1 |
Lv, PP; Ma, GH; Wang, LY; Wei, W; Yang, TY; Yue, H | 1 |
Cho, SH; Kim, K; Kim, SY; Kwon, IC; Lee, JH; Oh, KS; Oh, S; Yuk, SH | 1 |
Colson, YL; Grinstaff, MW; Wolinsky, JB | 1 |
Cui, F; Fang, L; Li, X; Liang, N; Piao, H; Sun, S | 1 |
Guo, X; Li, N; Liu, X; Ma, X; Yu, W; Zhang, Y; Zhou, H | 1 |
Cao, W; He, ZG; Lian, H; Liu, YH; Sun, J; Sun, YH; Wang, SL; Wang, YJ; Yu, YP | 1 |
Liu, Y; Ma, G; Ma, L; Nie, J; Xu, F; Xu, J | 1 |
Auzely-Velty, R; Boudou, T; Guillot, R; Jing, J; Kharkar, P; Paintrand, I; Picart, C | 1 |
Chang, J; Han, J; Ji, W; Liao, Z; Niu, R; Wang, H; Wang, X; Wu, B; Yu, M; Zhang, F; Zhang, H; Zhao, P | 1 |
Amoozgar, Z; Lin, Q; Park, J; Yeo, Y | 1 |
Lv, PP; Ma, GH; Ma, YF; Ni, DZ; Wei, W; Yu, R; Yue, H | 1 |
Kanwar, JR; Kanwar, RK; Mahidhara, G | 1 |
Shi, L; Tang, C; Yin, C | 1 |
Guo, H; Guo, S; Hao, L; Li, C; Wang, F; Zhang, D; Zhang, Q; Zheng, D | 1 |
Bertsch, A; Dashtimoghadam, E; Emami, SH; Hasani-Sadrabadi, MM; Majedi, FS; Renaud, P; Shokrgozar, MA; VanDersarl, JJ | 1 |
Lin, H; Qu, D; Xue, J; Zhang, C; Zhang, N | 1 |
Wang, Q; Wang, XY; Wei, XH; Zhang, L | 1 |
Chen, XM; Fu, Q; Liu, SY; Lv, PP; Ma, GH; Wei, W; Yue, H; Yue, ZG | 1 |
Du, Y; Hu, F; Li, C; Liu, F; Wang, Z; You, J; Yuan, H; Zhang, P; Zhou, J | 1 |
Gao, Y; Heng, L; Liu, Y; Pan, Z; Wang, Y; Yao, G | 1 |
Balakrishnan, B; Banerjee, R; Joshi, N; More, P; Saha, R; Shanmugam, T | 1 |
Jin, X; Ju, C; Sun, J; Zhang, C; Zi, P | 1 |
Ai, X; Ding, W; Han, X; He, Z; Kou, L; Li, L; Lian, H; Liu, X; Ren, G; Sun, J; Sun, Y; Wang, S; Wang, Y; Wu, C; Zhang, T; Zhang, Y | 1 |
Dai, T; Gao, Z; Li, S; Liu, L; Shen, N; Sun, Y; Wu, S; Xie, Y; Yang, E; Zhang, L | 1 |
Choi, K; Jeong, SY; Kim, K; Koo, H; Kwon, IC; Lee, SC; Min, KH; Park, JH; Park, K | 1 |
Choi, C; Jang, JY; Jang, MK; Kim, TH; Nah, JW; Nam, JP; Park, SC | 1 |
Tang, C; Yin, C; Zhang, S | 1 |
Ding, Y; Jin, X; Mo, R; Zhang, C; Zheng, W | 1 |
Ailhas, C; Bejaud, J; Groo, AC; Ivanova, T; Lagarce, F; Mircheva, K; Panaiotov, I; Saulnier, P | 1 |
Tang, C; Yin, C; Yu, B | 1 |
Ge, L; Wang, J; Wang, Y; Xu, H; Zhu, J | 1 |
Battogtokh, G; Ko, YT | 2 |
Chen, Y; Dahmani, FZ; Wang, X; Yao, J; Yin, L; Zhou, J | 1 |
Du, QG; Guo, XY; Han, S; Hao, ZM; Liu, GS; Lv, YF; Wang, P; Zhu, SM | 1 |
Emami, J; Hassanzadeh, F; Lavasanifar, A; Minaiyan, M; Mostafavi, A; Rezazadeh, M; Rostami, M; Sadeghi, H | 1 |
Chen, MX; Li, BK; Li, SS; Liang, J; Peng, DY; Yin, DK | 1 |
Cheng, XL; Feng, YJ; Fu, AR; Li, XJ; Song, RF; Wang, YH; Xiong, Y | 1 |
Cheng, J; Jiang, C; Sun, Z; Wang, F; Wang, H; Xie, H; Yu, B; Zhang, X; Zhou, L | 1 |
Emami, J; Hasanzadeh, F; Lavasanifar, A; Minaiyan, M; Mostafavi, A; Rezazadeh, M; Rostami, M; Sadeghi, H | 1 |
Gu, C; Jiang, H; Lang, M; Shi, W; Zhang, M | 1 |
Mishra, PR; Sharma, S; Shukla, P; Teja, BV; Verma, A | 1 |
Chen, Z; Fu, Q; Lv, P; Ma, G; Ni, D; Wei, W; Yue, H; Yue, Z; Zhang, L | 1 |
Fan, X; Li, L; Xu, W; Zhao, Y | 1 |
Chen, AZ; Chen, WG; Kang, YQ; Liu, YG; Wang, SB; Wu, WG; Ye, SF; Zhang, R | 1 |
Ge, Y; Li, L; Zhao, Y | 1 |
Arya, N; Katti, DS | 1 |
Han, J; Jiang, J; Xu, M; Zhang, D; Zhang, J; Zhang, X | 1 |
Cui, F; Fang, L; Hong, J; Liang, N; Sun, S; Tian, J | 1 |
Chen, R; Chen, YZ; Gao, F; Lou, KY; Wang, Y; Ye, YJ | 1 |
Chen, WL; Li, JZ; Liu, C; Liu, Y; Yang, SD; Yuan, ZQ; Zhang, CG; Zhang, XN; Zhou, XF; Zhu, WJ | 1 |
Jain, SK; Mahajan, M; Utreja, P | 1 |
Benoit, JP; Couez, D; Franconi, F; Lemaire, L; Lollo, G; Ullio-Gamboa, G; Vincent, M | 1 |
Abouelmagd, SA; Ku, YJ; Yeo, Y | 1 |
Jin, Y; Liu, Y; Ren, J; Yu, J; Zhang, L; Zhao, J | 1 |
Gao, Q; Hua, D; Huang, C; Wang, F; Yang, S; Yuan, J | 1 |
Mo, R; Qu, D; Xu, X; Xue, L; Zhang, C; Zhang, N; Zhang, X | 1 |
Chen, WL; Li, F; Li, JZ; Liu, C; Liu, Y; Ren, ZX; Yang, SD; Yuan, ZQ; Zhang, XN; Zhou, XF; Zhu, QL; Zhu, WJ | 1 |
Jiang, Y; Meng, X; Qi, X; Wu, Z | 1 |
Huo, M; Liu, J; Liu, Y; Qin, C; Wang, L; Xiao, Y; Yin, L; Yin, T; Zhou, J | 1 |
Cao, J; Chen, D; Deng, D; Gu, Y; Huang, S; Tang, L | 1 |
Bharathiraja, S; Bui, NQ; Lim, IG; Manivasagan, P; Oh, J | 1 |
Fei, J; Ping, Q; Sun, M; Zhang, F | 1 |
Gajbhiye, V; Jain, NK; Kesharwani, P; Nag, M | 1 |
Afzal, M; Alamgir, K; Bano, S; Nazir, S; Waraich, MM | 1 |
Cheng, B; Hu, F; Hu, Y; Liu, N; Tan, Y; Wen, L; Yuan, H | 1 |
Fereira, N; Godfrey, L; Odunze, U; Sasaki, K; Schätzlein, A; Soundararajan, R; Uchegbu, I | 1 |
Cheng, LC; Jiang, Y; Lu, HY; Qiu, LL; Xie, Y; Yang, Q | 1 |
Chen, H; Ding, Y; Hou, XS; Li, B; Ma, Y; Wang, P; Wu, DY; Zhang, C; Zhang, WJ | 1 |
Atyabi, F; Dinarvand, R; Ebrahimi, SM; Esfandyari-Manesh, M; Ghahremani, MH; Mohammadi, A; Nabavi, SM; Shahmoradi, E; Varnamkhasti, BS | 1 |
Argenziano, M; Battaglia, A; Bosco, O; Catalano, MG; Cavalli, R; D'Amelio, P; Fortunati, N; Frairia, R; Gontero, P; Marano, F; Peluso, R; Rinella, L; Sassi, F | 1 |
Almeida, A; Gonçalves, V; Sarmento, B; Silva, D | 1 |
Hasanzade, Z; Raissi, H | 1 |
Campos, J; Haidar, ZS; Varas-Godoy, M | 1 |
Chourasia, MK; Gothwal, A; Gupta, U; Khan, I; Kumar, V; Sharma, AK; Sharma, S; Singh, Y | 1 |
He, R; Yin, C | 1 |
Chen, Y; Feng, S; Gao, F; Liu, W; Yin, P; Yuan, Z | 1 |
Bai, A; Jiang, J; Liu, X; Liu, Y; Lv, H; Qiu, Y; Wu, C; Xu, X | 1 |
Fu, YN; Li, G; Li, Y; Tao, L; Wang, X; Yang, L; Yuan, Q | 1 |
Guo, Y; He, Y; Kong, M; Shang, L; Song, Q; Tan, S; Wu, T; Yin, Y; Zhang, D; Zhang, Z; Zhao, Y | 1 |
Ding, RL; Fu, SZ; He, WF; Lin, S; Liu, ZJ; Wen, QL; Wu, JB; Xie, F; Yang, LL | 1 |
Kannan, S; Mishra, SK | 1 |
Cai, H; Chen, Q; Fu, Y; Huo, M; Mu, Y; Xu, W; Yao, L; Yin, T; Yu, Y; Zhou, J | 1 |
Choudhury, SR; Dev, A; Karmakar, S; Kaundal, B; Singh, PK; Srivastava, AK | 1 |
Chen, W; Ding, D; Keidar, M; Liu, K; Tang, J; Wen, B; Yang, T; Zhang, W | 1 |
Chen, Q; Fu, Y; Huo, M; Li, L; Liu, Y; Mu, Y; Xu, W; Yin, T; Zhou, J | 1 |
Cao, A; Lan, Y; Liu, Y; Wang, W; Wei, S; Yang, J; Yang, T; Zhou, C | 1 |
Amighi, K; Gelbcke, M; Hecq, J; Mathieu, V; Mathivet, T; Rosière, R; Van Antwerpen, P; Van Woensel, M; Vermeersch, M; Wauthoz, N | 1 |
Gan, Z; He, F; Long, P; Su, H; Xiang, K; Xu, M; Yu, Q; Zhang, J; Zhang, X | 1 |
Jeong, YY; Lee, BI; Moon, MJ; Park, HJ; Park, IK; Surendran, SP; Thomas, RG | 1 |
Liu, YX; Wang, T; Zhang, XW; Zou, H | 1 |
Karnati, KR; Wang, Y | 1 |
Duan, H; Ji, X; Jiang, L; Qiu, J; Wang, T; Wang, Y | 1 |
Huang, C; Jiang, S; Wang, F; Yang, S; Yuan, J; Zhang, Q | 1 |
Gao, Y; Jiang, J; Liu, Y; Tao, L; Wu, C | 1 |
Li, JZ; Li, MW; Yan, M; Yuan, ZQ; Zhang, XN | 1 |
Cui, F; Gong, X; Li, Q; Liang, N; Sun, S; Yan, P | 1 |
Luna, JA; Mengatto, LN; Pesoa, JI; Rico, MJ; Rozados, VR; Scharovsky, OG | 1 |
Cui, F; Kawashima, Y; Li, L; Liang, N; Sun, S; Wang, D; Yan, P | 1 |
Batgerel, T; Jeong, YY; Kim, CS; Park, CH; Ramachandra Kurup Sasikala, A; Thomas, RG; Unnithan, AR | 1 |
Balasinor, NH; Chuttani, K; Manjappa, AS; Mishra, AK; Nanda, B; Ramachandra Murthy, RS | 1 |
Chu, K; Guo, Y; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W | 1 |
Hou, S; Ju, C; Qu, D; Qu, G; Tian, C; Xue, L; Zhang, C; Zhu, J | 1 |
Goto, M; Kamiya, N; Razi, MA; Wakabayashi, R | 1 |
Chen, L; Chen, LQ; Chu, XY; Gao, CH; Gao, CS; Gao, ZG; Ge, C; Huang, W; Jin, MJ; Meng, LW; Wang, YL | 1 |
Ding, X; Han, J; Luo, T; Pan, X; Tian, B; Zhang, J; Zhao, F | 1 |
Boloursaz, LA; Habibi Jouybari, M; Hosseini, S; Irani, M; Mahboobnia, K; Moradi, M | 1 |
Chen, X; Niu, S; Williams, GR; Wu, J; Zhang, X; Zheng, H; Zhu, LM | 1 |
Doan, VHM; Hoang, G; Jun, SW; Kim, CS; Kim, H; Kim, J; Manivasagan, P; Mondal, S; Nguyen, VT; Oh, J | 1 |
Akrami, M; Davaran, S; Farboudi, A; Irani, M; Nouri, A; Shirinzad, S; Sojoudi, P | 1 |
Chu, K; Han, L; Li, T; Ouyang, H; Qiu, L; Wang, X; Xu, W; Zhang, X | 1 |
Du, X; Li, J; Ma, J; Wang, G; Xu, L; Yin, S; Yu, H | 1 |
Jiao, M; Ju, C; Lin, H; Qu, D; Qu, G; Tian, C; Xue, J; Xue, L; Zhang, C | 1 |
Abasi, S; Ahmadi, Z; Ashrafizadeh, M; Dehghannoudeh, G; Khanbabaei, H; Mohamadi, N; Mohammadinejad, R; Tamaddondoust, RN; Thakur, VK; Zarrabi, A | 1 |
Chen, T; Feng, J; Qi, N; Tu, L; Wang, G; Wu, W; Zhang, W | 1 |
Clement Frey, F; Eberli, D; Kletzmayr, A; Millan, C; Zimmermann, M | 1 |
Huo, M; Liu, Y; Wang, L; Yang, M; Yin, T; Zhou, J | 1 |
Chen, L; Huang, K; Li, J; Tang, X; Wang, F | 1 |
Chakraborty, S; Kaur, N; Mathur, P; Shanavas, A; Yadav, P | 1 |
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; 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5 review(s) available for chitosan and paclitaxel
Article | Year |
---|---|
Chitosan hydrogel as a drug delivery carrier to control angiogenesis.
Topics: Animals; Biocompatible Materials; Chitosan; Cross-Linking Reagents; Drug Delivery Systems; Fibroblast Growth Factor 2; Hydrogels; Mice; Mice, Inbred Strains; Neovascularization, Pathologic; Occlusive Dressings; Paclitaxel; Rabbits; Ultraviolet Rays; Wound Healing | 2006 |
Controlled releases of FGF-2 and paclitaxel from chitosan hydrogels and their subsequent effects on wound repair, angiogenesis, and tumor growth.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chitosan; Delayed-Action Preparations; Drug Carriers; Fibroblast Growth Factor 2; Hydrogels; Neoplasms, Experimental; Neovascularization, Physiologic; Paclitaxel; Wound Healing | 2006 |
Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Chitosan; Decanoic Acids; Drug Delivery Systems; Gels; Humans; Microspheres; Nanoparticles; Neoplasms; Paclitaxel; Polyesters; Polymers | 2012 |
Chitosan-based advanced materials for docetaxel and paclitaxel delivery: Recent advances and future directions in cancer theranostics.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Chitosan; Docetaxel; Drug Carriers; Humans; Hydrogen-Ion Concentration; Molecular Targeted Therapy; Nanoparticles; Neoplasms; Oxidation-Reduction; Paclitaxel; Solubility; Static Electricity; Theranostic Nanomedicine | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
1 trial(s) available for chitosan and paclitaxel
201 other study(ies) available for chitosan and paclitaxel
Article | Year |
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Development of novel chitosan derivatives as micellar carriers of taxol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Chitin; Chitosan; Dogs; Drug Carriers; Erythrocytes; Hemolysis; Injections, Intravenous; Lauric Acids; Membrane Potentials; Micelles; Paclitaxel; Particle Size; Solubility | 1998 |
A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel.
Topics: Animals; Body Temperature; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Drug Screening Assays, Antitumor; Drug Stability; Evaluation Studies as Topic; Female; Gamma Rays; Glycerophosphates; Hydrogels; Injections, Intralesional; Injections, Intravenous; Mammary Neoplasms, Experimental; Materials Testing; Mice; Mice, Inbred BALB C; Paclitaxel; Solutions; Sterilization | 2004 |
Intra-articular treatment of arthritis with microsphere formulations of paclitaxel: biocompatibility and efficacy determinations in rabbits.
Topics: Animals; Arthritis; Biocompatible Materials; Chitosan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Inflammation; Injections, Intra-Articular; Joints; Materials Testing; Microspheres; Paclitaxel; Rabbits; Synovial Fluid; Treatment Outcome | 2004 |
Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system.
Topics: Antineoplastic Agents, Phytogenic; Chitin; Chitosan; Chromatography, High Pressure Liquid; Drug Carriers; Ethanol; Micelles; Microscopy, Electron, Transmission; Models, Chemical; Molecular Conformation; Paclitaxel; Polymers; Sodium Chloride; Spectrometry, Fluorescence; Temperature; Time Factors; Water; X-Ray Diffraction | 2004 |
Delivery platform for hydrophobic drugs: prodrug approach combined with self-assembled multilayers.
Topics: Animals; Cell Survival; Chitosan; Drug Delivery Systems; Hyaluronic Acid; Hydrophobic and Hydrophilic Interactions; Macrophages; Mice; Paclitaxel; Prodrugs; Succinates | 2005 |
Development and characterization of biodegradable chitosan films for local delivery of Paclitaxel.
Topics: Animals; Biodegradation, Environmental; Chemistry, Pharmaceutical; Chitosan; Dosage Forms; Drug Carriers; Mice; Paclitaxel | 2004 |
Efficacy of an intratumoral controlled release formulation of clusterin antisense oligonucleotide complexed with chitosan containing paclitaxel or docetaxel in prostate cancer xenograft models.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Clusterin; Delayed-Action Preparations; Docetaxel; Drug Therapy, Combination; Glycoproteins; Humans; Injections, Intralesional; Male; Mice; Mice, Inbred BALB C; Molecular Chaperones; Neoplasm Transplantation; Ointments; Oligonucleotides, Antisense; Paclitaxel; Prostatic Neoplasms; Taxoids; Transplantation, Heterologous; Xenograft Model Antitumor Assays | 2005 |
In vitro and in vivo characterization of a novel biocompatible polymer-lipid implant system for the sustained delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Biodegradation, Environmental; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Implants; Female; Humans; Linear Models; Mice; Mice, Inbred Strains; Paclitaxel; Phosphatidylcholines; Solubility | 2005 |
Hybrid films from blends of chitosan and egg phosphatidylcholine for localized delivery of paclitaxel.
Topics: Adsorption; Algorithms; Animals; Cell Line, Tumor; Cell Survival; Chitosan; CHO Cells; Cricetinae; Eggs; Excipients; Female; Humans; Lipids; Microspheres; Ovarian Neoplasms; Paclitaxel; Phosphatidylcholines; Spectroscopy, Fourier Transform Infrared | 2005 |
Controlled release of paclitaxel from photocrosslinked chitosan hydrogels and its subsequent effect on subcutaneous tumor growth in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Lewis Lung; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Stability; Endothelial Cells; Hydrogels; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Photochemistry; Skin Neoplasms | 2005 |
In vivo pharmacokinetic and tissue distribution studies in mice of alternative formulations for local and systemic delivery of Paclitaxel: gel, film, prodrug, liposomes and micelles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Carbon Radioisotopes; Chitosan; Gels; Glycerol; Half-Life; Injections, Intravenous; Injections, Subcutaneous; Liposomes; Male; Mice; Micelles; Motion Pictures; Paclitaxel; Prodrugs; Tissue Distribution | 2005 |
Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Glycerol; Humans; Hydrophobic and Hydrophilic Interactions; Injections, Intravenous; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nanostructures; Paclitaxel; Technology, Pharmaceutical; Time Factors; Treatment Outcome | 2006 |
Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel.
Topics: Biocompatible Materials; Chemical Phenomena; Chemistry, Physical; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carriers; In Vitro Techniques; Materials Testing; Micelles; Nanostructures; Nanotechnology; Oligosaccharides; Paclitaxel; Stearic Acids | 2006 |
An ex vivo characterization of Paclitaxel loaded chitosan films after implantation in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Calorimetry, Differential Scanning; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Glycerol; Mice; Microscopy, Electron, Scanning; Paclitaxel; Poloxamer; Spectroscopy, Fourier Transform Infrared | 2006 |
N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Endocytosis; Exocytosis; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Histidine; Humans; Microscopy, Confocal; Nanostructures; Paclitaxel; Particle Size | 2006 |
[Preparation of paclitaxel-loaded chitosan polymeric micelles and influence of surface charges on their tissue biodistribution in mice].
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Female; Liver; Lung; Mice; Micelles; Paclitaxel; Particle Size; Spleen; Surface Properties; Tissue Distribution | 2006 |
Novel biocompatible intraperitoneal drug delivery system increases tolerability and therapeutic efficacy of paclitaxel in a human ovarian cancer xenograft model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biocompatible Materials; Chitosan; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Implants; Eggs; Female; Glycerol; Humans; Injections, Intraperitoneal; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphatidylcholines; Xenograft Model Antitumor Assays | 2007 |
Polymeric micelles with glycolipid-like structure and multiple hydrophobic domains for mediating molecular target delivery of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Chitosan; Drug Carriers; Endocytosis; Glycolipids; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Molecular Structure; Paclitaxel; Particle Size; Polymers; Water | 2007 |
Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel.
Topics: Alkanesulfonic Acids; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Biological Availability; Carcinoma, Ehrlich Tumor; Carcinoma, Lewis Lung; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Female; Hemolysis; Humans; Liver Neoplasms, Experimental; Male; Materials Testing; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Micelles; Paclitaxel; Rats; Rats, Sprague-Dawley; Safety; Sarcoma 180; Tissue Distribution | 2008 |
Drug release mechanism of paclitaxel from a chitosan-lipid implant system: effect of swelling, degradation and morphology.
Topics: Animals; Ascites; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Drug Implants; Female; Humans; Lipids; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Paclitaxel; Prostheses and Implants | 2008 |
A novel nanoparticle formulation for sustained paclitaxel delivery.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Emulsions; Female; Glycerides; Humans; Inhibitory Concentration 50; Kinetics; Microscopy, Electron, Transmission; Nanoparticles; Paclitaxel; Particle Size; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors | 2008 |
Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles | 2009 |
The intracellular uptake ability of chitosan-coated Poly (D,L-lactide-co-glycolide) nanoparticles.
Topics: Adhesives; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Electrochemistry; Excipients; Humans; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Conjugated chitosan as a novel platform for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Female; Humans; Mice; Molecular Structure; Molecular Weight; Paclitaxel | 2008 |
[Solubilizing and sustained-releasing abilities and safety preliminary evaluation for paclitaxel based on N-octyl-O, N-carboxymethyl chitosan polymeric micelles].
Topics: Animals; Antineoplastic Agents, Phytogenic; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Female; Guinea Pigs; Hemolysis; Humans; Hypersensitivity, Immediate; Male; Mice; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polymers | 2008 |
Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Synthesis of novel pH-sensitive chitosan graft copolymers and micellar solubilization of paclitaxel.
Topics: Benzene; Calorimetry, Differential Scanning; Chitosan; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Electron, Transmission; Paclitaxel; Regression Analysis; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Surface Tension; Time Factors; X-Ray Diffraction | 2009 |
Biodegradable nanoparticles based on linoleic acid and poly(beta-malic acid) double grafted chitosan derivatives as carriers of anticancer drugs.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Cell Proliferation; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Hydrogen-Ion Concentration; Injections, Intravenous; Linoleic Acid; Macromolecular Substances; Malates; Male; Materials Testing; Mice; Nanoparticles; Paclitaxel; Particle Size; Polymers; Surface Properties; Water; Xenograft Model Antitumor Assays | 2009 |
Chitosan/pshRNA plasmid nanoparticles targeting MDR1 gene reverse paclitaxel resistance in ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chitosan; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Nanoparticles; Ovarian Neoplasms; Paclitaxel; Plasmids; RNA, Messenger; RNA, Small Interfering; Transfection | 2009 |
PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: in vitro characterization and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Chitosan; Female; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Tissue Distribution | 2009 |
The in vitro sub-cellular localization and in vivo efficacy of novel chitosan/GMO nanostructures containing paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Female; Humans; Mice; Mice, SCID; Microscopy, Confocal; Nanostructures; Paclitaxel; Subcellular Fractions | 2009 |
Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paclitaxel: synthesis, characterization, and in vivo biodistribution.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbohydrate Sequence; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Compounding; Drug Stability; Female; Glycols; HeLa Cells; Humans; Mice; Mice, Nude; Molecular Sequence Data; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Solubility; Thermodynamics; Tissue Distribution | 2009 |
[Preparation and drug release property of paclitaxel nanoparticles].
Topics: Antineoplastic Agents, Phytogenic; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polymers | 2009 |
Discriminated effects of thiolated chitosan-coated pMMA paclitaxel-loaded nanoparticles on different normal and cancer cell lines.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Humans; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; NIH 3T3 Cells; Paclitaxel; Polymethyl Methacrylate | 2010 |
Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chitosan; Drug Carriers; Drug Delivery Systems; Folic Acid; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Nanoparticles; NIH 3T3 Cells; Paclitaxel; Particle Size; Stearic Acids; Surface Properties | 2011 |
Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carbocyanines; Carcinoma, Squamous Cell; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Humans; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Paclitaxel | 2010 |
Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chitosan; Dialysis; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Stability; Female; Glycerol; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Maximum Tolerated Dose; Mice; Micelles; Paclitaxel; Solubility; Spectroscopy, Fourier Transform Infrared; Toxicity Tests, Acute | 2010 |
Chitosan film containing poly(D,L-lactic-co-glycolic acid) nanoparticles: a platform for localized dual-drug release.
Topics: Chitosan; Drug Compounding; Drug Delivery Systems; Drug Stability; Fluoresceins; Gold; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2010 |
Paclitaxel-loaded, folic-acid-targeted and TAT-peptide-conjugated polymeric liposomes: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Female; Folate Receptors, GPI-Anchored; Folic Acid; Gene Products, tat; Humans; KB Cells; Liposomes; Mice; Mice, SCID; Microscopy, Electron, Transmission; Paclitaxel; Solubility; Surface Properties; Xenograft Model Antitumor Assays | 2010 |
Folate-targeted drug-delivery systems prepared by nano-comminution.
Topics: Chitosan; Cross-Linking Reagents; Drug Delivery Systems; Drug Stability; Excipients; Folic Acid; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Naproxen; Paclitaxel; Particle Size; Polyphosphates | 2011 |
Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Chitosan; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred BALB C; Molecular Conformation; Molecular Weight; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size; Polyethylene Glycols; Solubility; Surface Properties | 2010 |
Enhanced oral absorption of paclitaxel in N-deoxycholic acid-N, O-hydroxyethyl chitosan micellar system.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chitosan; Deoxycholic Acid; Drug Carriers; Intestinal Absorption; Micelles; Paclitaxel; Rats; Rats, Sprague-Dawley | 2010 |
In vivo evaluation of novel chitosan graft polymeric micelles for delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Polymers; Solubility; Tissue Distribution | 2011 |
Enhanced cellular association of paclitaxel delivered in chitosan-PLGA particles.
Topics: Adhesiveness; Animals; Antineoplastic Agents, Phytogenic; Boron Compounds; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Inhibitory Concentration 50; Lactic Acid; Mammary Neoplasms, Animal; Mice; Microscopy, Confocal; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
pH triggered injectable amphiphilic hydrogel containing doxorubicin and paclitaxel.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Hydrogels; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Paclitaxel; Polyethylene Glycols; Rheology; Skin Neoplasms; Survival Rate; Time Factors | 2011 |
The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles.
Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Biological Availability; Caco-2 Cells; Calcium Channel Blockers; Chitosan; Endocytosis; Humans; Materials Testing; Micelles; Paclitaxel; Rats; Rats, Sprague-Dawley; Verapamil | 2011 |
Preparation, characterization, cytotoxicity and drug release behavior of liposome-enveloped paclitaxel/Fe3O4 nanoparticles.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Drug Delivery Systems; Ferric Compounds; Humans; Liposomes; Magnetic Resonance Spectroscopy; Metal Nanoparticles; Microscopy, Electron, Transmission; Nanoconjugates; Paclitaxel; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2011 |
Novel polymer coupled lipid nanoparticle of paclitaxel with synergistic enhanced efficacy against cancer.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Humans; Lipids; Nanocapsules; Paclitaxel; Treatment Outcome | 2011 |
Antitumor efficacy, tumor distribution and blood pharmacokinetics of chitosan/glyceryl-monooleate nanostructures containing paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chitosan; Drug Delivery Systems; Female; Glycerides; Leukocyte Count; Mice; Mice, Inbred BALB C; Nanostructures; Neoplasms; Paclitaxel | 2011 |
[Preparation of superparamagnetic paclitaxel nanoparticles from modified chitosan and their cytotoxicity against malignant brain glioma].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Compounding; Ferric Compounds; Glioma; Humans; Magnetics; Metal Nanoparticles; Nanoparticles; Paclitaxel | 2011 |
Nanoparticle-based biocompatible and targeted drug delivery: characterization and in vitro studies.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Caco-2 Cells; Cell Survival; Chitosan; Colonic Neoplasms; Dextran Sulfate; Drug Carriers; Drug Compounding; Fluorescence; Humans; Kinetics; Microscopy, Electron, Scanning; Molecular Targeted Therapy; Nanoparticles; Paclitaxel; Particle Size; Photoelectron Spectroscopy; Polyethylene Glycols; Surface Properties; Wheat Germ Agglutinins | 2011 |
Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Chitosan; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; Fluorescence; Folic Acid; Humans; Inhibitory Concentration 50; Micelles; Microscopy, Electron, Scanning; Paclitaxel; Particle Size; Polymers; Verapamil; X-Ray Diffraction | 2011 |
Facilitated intracellular delivery of peptide-guided nanoparticles in tumor tissues.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasm Transplantation; Neoplasms; Oligopeptides; Paclitaxel; Receptors, Interleukin-4; Tumor Burden | 2012 |
Long circulating chitosan/PEG blended PLGA nanoparticle for tumor drug delivery.
Topics: Adsorption; Animals; Antineoplastic Agents; Biological Transport; Capsules; Cattle; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Stability; Female; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macrophages; Mice; Molecular Weight; Nanoparticles; Paclitaxel; Phagocytosis; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine | 2011 |
Porous quaternized chitosan nanoparticles containing paclitaxel nanocrystals improved therapeutic efficacy in non-small-cell lung cancer after oral administration.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Carcinoma, Non-Small-Cell Lung; Cell Line; Chitosan; Drug Carriers; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Paclitaxel; Quaternary Ammonium Compounds; Xenograft Model Antitumor Assays | 2011 |
Enhancement of the targeting capabilities of the Paclitaxel-loaded pluronic nanoparticles with a glycol chitosan/heparin composite.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Cell Line, Tumor; Chitosan; Drug Carriers; Heparin; Male; Mice; Microscopy, Electron, Scanning; Nanoparticles; Neoplasm Transplantation; Neoplasms; Paclitaxel; Poloxamer; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Tissue Distribution | 2012 |
α-Tocopherol succinate-modified chitosan as a micellar delivery system for paclitaxel: preparation, characterization and in vitro/in vivo evaluations.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Female; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Male; Mice; Micelles; Microscopy, Electron, Transmission; Paclitaxel; Particle Size; Rabbits; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Tocopherols; Uterine Cervical Neoplasms | 2012 |
Synthesis and characterization of amphiphilic chitosan derivatives as a nano-carrier for paclitaxel delivery.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Deoxycholic Acid; Drug Carriers; Drug Compounding; Epoxy Compounds; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Microscopy, Confocal; Nanoparticles; Nanotechnology; Paclitaxel; Particle Size; Propanols; Quaternary Ammonium Compounds; Solubility; Surface-Active Agents; Technology, Pharmaceutical | 2011 |
Supramolecular micellar nanoaggregates based on a novel chitosan/vitamin E succinate copolymer for paclitaxel selective delivery.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Diffusion; Female; Humans; Micelles; Nanocapsules; Paclitaxel; Polyethylene Glycols; Vitamin E | 2011 |
Design and characterization of antitumor drug paclitaxel-loaded chitosan nanoparticles by W/O emulsions.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Chitosan; Drug Carriers; Emulsions; Humans; Nanoparticles; Paclitaxel; Particle Size | 2012 |
Folate-mediated targeted and intracellular delivery of paclitaxel using a novel deoxycholic acid-O-carboxymethylated chitosan-folic acid micelles.
Topics: Absorbable Implants; Breast Neoplasms; Cell Membrane; Cell Nucleus; Chitosan; Drug Carriers; Female; Folic Acid; Humans; Micelles; Microscopy, Fluorescence; Paclitaxel; Rhodamines; Solubility; Tumor Cells, Cultured | 2012 |
Polyelectrolyte multilayer nanoshells with hydrophobic nanodomains for delivery of Paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Drug Stability; Humans; Hyaluronic Acid; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Nanoshells; Paclitaxel; Polyamines; Polyelectrolytes; Polylysine; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2012 |
Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Female; Folic Acid; HeLa Cells; Humans; Lactic Acid; Lipids; Mice; Mice, SCID; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Distribution | 2012 |
Low molecular-weight chitosan as a pH-sensitive stealth coating for tumor-specific drug delivery.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Confocal; Molecular Structure; Molecular Weight; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Targeted delivery of insoluble cargo (paclitaxel) by PEGylated chitosan nanoparticles grafted with Arg-Gly-Asp (RGD).
Topics: Animals; Cell Line, Tumor; Chitosan; Drug Carriers; Emulsions; Injections, Intravenous; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nanoparticles; NIH 3T3 Cells; Oligopeptides; Paclitaxel | 2012 |
Novel alginate-enclosed chitosan-calcium phosphate-loaded iron-saturated bovine lactoferrin nanocarriers for oral delivery in colon cancer therapy.
Topics: Administration, Oral; Alginates; Animals; Antineoplastic Agents; Calcium Phosphates; Cattle; Chitosan; Colonic Neoplasms; Endocytosis; Glucuronic Acid; Hexuronic Acids; Humans; Iron; Lactoferrin; Mice; Nanoparticles; Paclitaxel; Xenograft Model Antitumor Assays | 2012 |
Glycyrrhizin-modified O-carboxymethyl chitosan nanoparticles as drug vehicles targeting hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Endocytosis; Female; Glycyrrhizic Acid; Humans; Liver; Liver Neoplasms; Mice; Nanoparticles; Paclitaxel; Particle Size; Rhodamines; Spectroscopy, Fourier Transform Infrared; Static Electricity; Subcellular Fractions; Tissue Distribution; Treatment Outcome; Tumor Burden | 2012 |
Tissue distribution and pharmacokinetics evaluation of DOMC-FA micelles for intravenous delivery of PTX.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Calorimetry, Differential Scanning; Chitosan; Deoxycholic Acid; Drug Carriers; Folic Acid; Injections, Intravenous; Mice; Mice, Inbred Strains; Micelles; Microscopy, Electron, Transmission; Organ Specificity; Paclitaxel; Particle Size; Rabbits; Solubility; Surface Properties; Tissue Distribution | 2013 |
Microfluidic assisted self-assembly of chitosan based nanoparticles as drug delivery agents.
Topics: Antineoplastic Agents, Phytogenic; Chitosan; Drug Carriers; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Microfluidic Analytical Techniques; Nanoparticles; Paclitaxel; Particle Size | 2013 |
In vitro evaluation on novel modified chitosan for targeted antitumor drug delivery.
Topics: Antineoplastic Agents; Breast Neoplasms; Chitosan; Drug Carriers; Female; Folic Acid; Humans; MCF-7 Cells; Micelles; Paclitaxel; Polymers | 2013 |
Molecular dynamics of paclitaxel encapsulated by salicylic acid-grafted chitosan oligosaccharide aggregates.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Chitosan; Hydrogen Bonding; Microscopy, Electron, Transmission; Models, Molecular; Molecular Dynamics Simulation; Oligosaccharides; Paclitaxel; Salicylic Acid | 2013 |
Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression.
Topics: Absorption; Animals; Antineoplastic Agents; Caco-2 Cells; Carbocyanines; Carcinoma, Lewis Lung; Cell Death; Cell Proliferation; Chitosan; Drug Delivery Systems; Endocytosis; Flow Cytometry; Gene Silencing; Gene Transfer Techniques; Humans; Intracellular Space; Male; Mice; Nanoparticles; Neoplasms; Paclitaxel; Permeability; Quaternary Ammonium Compounds; RNA, Small Interfering; Telomerase; Tissue Distribution; Xenograft Model Antitumor Assays | 2013 |
Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres.
Topics: Ablation Techniques; Animals; Cell Death; Cell Line, Tumor; Chitosan; Diagnostic Imaging; Drug Delivery Systems; Endocytosis; Glycolipids; Gold; Humans; Light; Mice; Micelles; Nanospheres; Neoplasms; Oligosaccharides; Paclitaxel; Particle Size; Peptides; Polymers; Receptor, EphB4; Spectroscopy, Near-Infrared; Static Electricity; Stearic Acids; Temperature | 2013 |
Amphiphilic N-(2,3-dihydroxypropyl)-chitosan-cholic acid micelles for paclitaxel delivery.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Chitosan; Cholic Acid; Delayed-Action Preparations; Drug Carriers; Humans; Kinetics; MCF-7 Cells; Micelles; Paclitaxel; Particle Size; Surface-Active Agents | 2013 |
Carboxymethyl-chitosan-tethered lipid vesicles: hybrid nanoblanket for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Female; HeLa Cells; Humans; Lipids; Melanoma, Experimental; Mice; Nanoparticles; Paclitaxel; Phosphatidylethanolamines; Rats; Rats, Wistar; Transport Vesicles | 2013 |
Thermosensitive micelles-hydrogel hybrid system based on poloxamer 407 for localized delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Liver; Liver Neoplasms; Male; Mice; Micelles; Paclitaxel; Poloxamer; Rheology; Temperature | 2013 |
Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism.
Topics: Acetylcysteine; Animals; Chitosan; Drug Carriers; Micelles; Mucus; Paclitaxel; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Thermogravimetry; Vitamin E | 2013 |
Preparation and drug release mechanism of CTS-TAX-NP-MSCs drug delivery system.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Movement; Chitosan; Drug Compounding; Drug Delivery Systems; Humans; Lactic Acid; Mesenchymal Stem Cells; Mice; Multidrug Resistance-Associated Proteins; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2013 |
Enhanced drug-loading and therapeutic efficacy of hydrotropic oligomer-conjugated glycol chitosan nanoparticles for tumor-targeted paclitaxel delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Humans; Mice; Mice, Nude; Nanoparticles; Paclitaxel | 2013 |
Encapsulation of paclitaxel into lauric acid-O-carboxymethyl chitosan-transferrin micelles for hydrophobic drug delivery and site-specific targeted delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Hemolysis; Humans; Lauric Acids; Micelles; Paclitaxel; Rats; Transferrin | 2013 |
Effects of poly(ethylene glycol) grafting density on the tumor targeting efficacy of nanoparticles with ligand modification.
Topics: Animals; Animals, Outbred Strains; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Folic Acid; Humans; Ligands; Linoleic Acid; Liver; Liver Neoplasms, Experimental; Malates; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymers; Random Allocation; Surface Properties; Tissue Distribution | 2015 |
Paclitaxel-loaded N-octyl-O-sulfate chitosan micelles for superior cancer therapeutic efficacy and overcoming drug resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Male; Membrane Fluidity; Mice; Mice, Inbred ICR; Micelles; Paclitaxel; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Development of 2D and 3D mucus models and their interactions with mucus-penetrating paclitaxel-loaded lipid nanocapsules.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Diffusion; Drug Carriers; Models, Biological; Mucus; Nanocapsules; Paclitaxel; Particle Size; Polyethylene Glycols; Surface Properties; Swine | 2014 |
Enhanced antitumor efficacy of folate modified amphiphilic nanoparticles through co-delivery of chemotherapeutic drugs and genes.
Topics: Adsorption; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Deoxyribonuclease I; Drug Delivery Systems; Endocytosis; Female; Folic Acid; Gene Transfer Techniques; Humans; Inhibitor of Apoptosis Proteins; Linoleic Acid; Malates; Mice; Nanoparticles; Paclitaxel; Particle Size; Polymers; Repressor Proteins; RNA, Messenger; Serum Albumin, Bovine; Static Electricity; Surface-Active Agents; Survivin | 2014 |
Development of a thermally responsive nanogel based on chitosan-poly(N-isopropylacrylamide-co-acrylamide) for paclitaxel delivery.
Topics: Acrylic Resins; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Endocytosis; Erythrocytes; Gels; Hemolysis; HT29 Cells; Humans; Mice; Nanostructures; Paclitaxel; Rats, Sprague-Dawley; Transition Temperature; Xenograft Model Antitumor Assays | 2014 |
Self-assembled chitosan-ceramide nanoparticle for enhanced oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Cell Line, Tumor; Ceramides; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Emulsions; Humans; MCF-7 Cells; Melanoma, Experimental; Mice; Nanoparticles; Paclitaxel; Particle Size | 2014 |
Amphiphilic carboxymethyl chitosan-quercetin conjugate with P-gp inhibitory properties for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chitosan; Delayed-Action Preparations; Hep G2 Cells; Humans; Intestinal Absorption; Male; Mice; Micelles; Neoplasms; Paclitaxel; Quercetin; Rats; Rats, Sprague-Dawley; Solubility | 2014 |
Paclitaxel and gemcitabine combinational drug-loaded mucoadhesive delivery system in the treatment of colon cancers.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Survival; Chitosan; Colonic Neoplasms; Deoxycytidine; Drug Carriers; Drug Liberation; Drug Therapy, Combination; Gemcitabine; Humans; Mice; Nanoparticles; Paclitaxel; Succinic Anhydrides; Survival Rate; Xenograft Model Antitumor Assays | 2015 |
Self-assembled polymeric nanoparticle of PEGylated chitosan-ceramide conjugate for systemic delivery of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Ceramides; Chitosan; Dicyclohexylcarbodiimide; Drug Carriers; Drug Delivery Systems; Humans; MCF-7 Cells; Micelles; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Succinimides; Technology, Pharmaceutical | 2014 |
Co-delivery of paclitaxel and α-tocopherol succinate by novel chitosan-based polymeric micelles for improving micellar stability and efficacious combination therapy.
Topics: alpha-Tocopherol; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Stability; Female; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Oligosaccharides; Ovarian Neoplasms; Paclitaxel; Particle Size | 2015 |
Layer-by-layer assembly of chitosan stabilized multilayered liposomes for paclitaxel delivery.
Topics: Acrylic Resins; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Cholesterol; Drug Delivery Systems; Female; Humans; Liposomes; Paclitaxel; Phospholipids; Temperature; Uterine Cervical Neoplasms | 2014 |
Paclitaxel-loaded trimethyl chitosan-based polymeric nanoparticle for the effective treatment of gastroenteric tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Chitosan; Drug Delivery Systems; Gastrointestinal Neoplasms; Humans; Intestine, Small; Mice; Nanoparticles; Paclitaxel; Polymers; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Deoxycholic acid-modified chitooligosaccharide/mPEG-PDLLA mixed micelles loaded with paclitaxel for enhanced antitumor efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitin; Chitosan; Delayed-Action Preparations; Deoxycholic Acid; Drug Carriers; Drug Compounding; Female; Humans; Lung Neoplasms; Male; Mice, Nude; Micelles; Nanoparticles; Oligosaccharides; Paclitaxel; Polyesters; Polyethylene Glycols; Random Allocation; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Surface Properties; Tumor Burden; Xenograft Model Antitumor Assays; Zebrafish | 2014 |
In vivo pharmacokinetics, biodistribution and anti-tumor effect of paclitaxel-loaded targeted chitosan-based polymeric micelle.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Mice; Micelles; Paclitaxel; Polyethylene Glycols | 2016 |
Effects of amphiphilic chitosan-g-poly(ε-caprolactone) polymer additives on paclitaxel release from drug eluting implants.
Topics: Chitosan; Chromatography, High Pressure Liquid; Drug Implants; Kinetics; Microscopy, Electron, Scanning; Paclitaxel; Polyesters; Spectrophotometry, Ultraviolet; Stents; Surface Properties | 2014 |
Development of stabilized Paclitaxel nanocrystals: In-vitro and in-vivo efficacy studies.
Topics: Administration, Oral; Alginates; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Drug Compounding; Drug Stability; Glucuronic Acid; Hexuronic Acids; Humans; Male; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Polysorbates; Polystyrenes; Rats, Wistar; Solubility; Surface-Active Agents | 2015 |
Programmed co-delivery of paclitaxel and doxorubicin boosted by camouflaging with erythrocyte membrane.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Chitosan; Doxorubicin; Drug Carriers; Erythrocyte Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Fields; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Oligopeptides; Paclitaxel; Polyethylene Glycols; Survival Rate; Tissue Distribution | 2015 |
Cysteine modified and bile salt based micelles: preparation and application as an oral delivery system for paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Cell Survival; Chitosan; Cysteine; Drug Carriers; Drug Stability; Humans; Male; MCF-7 Cells; Micelles; Paclitaxel; Poloxamer; Rats; Rats, Wistar; Sodium Cholate; Surface-Active Agents | 2015 |
Codelivery of paclitaxel and small interfering RNA by octadecyl quaternized carboxymethyl chitosan-modified cationic liposome for combined cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cations; Chitosan; Drug Carriers; Liposomes; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Neoplasms; Paclitaxel; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared | 2015 |
Preparation of sodium cholate-based micelles through non-covalent ıbonding interaction and application as oral delivery systems for paclitaxel.
Topics: Acrylates; Animals; Biological Availability; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Female; Humans; MCF-7 Cells; Micelles; Paclitaxel; Rats; Sodium Cholate | 2016 |
Poly(d,l-lactide-co-glycolide)-chitosan composite particles for the treatment of lung cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Synergism; Humans; Lactic Acid; Lung Neoplasms; Nanocomposites; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Topotecan | 2015 |
Polymeric nanoparticles based on chitooligosaccharide as drug carriers for co-delivery of all-trans-retinoic acid and paclitaxel.
Topics: Animals; Cell Death; Chitin; Chitosan; Drug Carriers; Drug Delivery Systems; Endocytosis; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescence; Hemolysis; Hep G2 Cells; Humans; Mice; Microscopy, Confocal; Nanoparticles; Oligosaccharides; Paclitaxel; Particle Size; Polymers; Proton Magnetic Resonance Spectroscopy; Rabbits; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tretinoin | 2015 |
In vivo pharmacokinetics, biodistribution and antitumor effect of paclitaxel-loaded micelles based on α-tocopherol succinate-modified chitosan.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Half-Life; Humans; MCF-7 Cells; Mice; Micelles; Paclitaxel; Rats; Rats, Wistar; Succinic Acid; Tissue Distribution | 2016 |
The preparation, characterization, and pharmacokinetic studies of chitosan nanoparticles loaded with paclitaxel/dimethyl-β-cyclodextrin inclusion complexes.
Topics: Animals; beta-Cyclodextrins; Chitosan; Male; Nanoparticles; Paclitaxel; Rats; Rats, Wistar | 2015 |
Systemic delivery of micelles loading with paclitaxel using N-succinyl-palmitoyl-chitosan decorated with cRGDyK peptide to inhibit non-small-cell lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Chitosan; Drug Delivery Systems; Female; Humans; Lung Neoplasms; Mice, Nude; Micelles; Microtubules; Paclitaxel; Peptides, Cyclic; Tumor Burden | 2015 |
Paclitaxel Loaded Nanoliposomes in Thermosensitive Hydrogel: A Dual Approach for Sustained and Localized Delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Half-Life; Humans; Hydrogels; Liposomes; Mice; Nanoparticles; Paclitaxel; Phosphates; Temperature | 2016 |
Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Chitosan; Drug Screening Assays, Antitumor; Drug Stability; Female; Glioblastoma; Lipids; Magnetic Resonance Imaging; Mice; Nanocapsules; Oligodeoxyribonucleotides; Paclitaxel | 2015 |
Low molecular weight chitosan-coated polymeric nanoparticles for sustained and pH-sensitive delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mice; Molecular Weight; Nanoparticles; Paclitaxel; Phagocytosis; Static Electricity | 2015 |
Self-aggregated nanoparticles of linoleic acid-modified glycol chitosan conjugate as delivery vehicles for paclitaxel: preparation, characterization and evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Chitosan; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Linoleic Acid; Liver Neoplasms; Male; Mice; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Particle Size | 2015 |
A novel preparation method of paclitaxcel-loaded folate-modified chitosan microparticles and in vitro evaluation.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Fibroblasts; Folic Acid; Humans; Liver Neoplasms; Mice; Nanoparticles; Paclitaxel | 2016 |
Nanocomposite hydrogel incorporating gold nanorods and paclitaxel-loaded chitosan micelles for combination photothermal-chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Combined Modality Therapy; Drug Carriers; Drug Stability; Gold; Hydrogels; Hyperthermia, Induced; Injections, Intralesional; Laser Therapy; Male; Mice; Micelles; Nanocomposites; Nanotubes; Neoplasms; Paclitaxel; Phototherapy; Xenograft Model Antitumor Assays | 2016 |
Binary-copolymer system base on low-density lipoprotein-coupled N-succinyl chitosan lipoic acid micelles for co-delivery MDR1 siRNA and paclitaxel, enhances antitumor effects via reducing drug.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Chitosan; Female; Gene Transfer Techniques; Humans; Lipoproteins, LDL; MCF-7 Cells; Mice; Mice, Nude; Micelles; Neoplasm Proteins; Neoplasms, Experimental; Paclitaxel; RNA, Small Interfering; Thioctic Acid; Xenograft Model Antitumor Assays | 2017 |
Modified chitosan thermosensitive hydrogel enables sustained and efficient anti-tumor therapy via intratumoral injection.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Chitosan; Drug Carriers; Drug Liberation; Glutaral; Hydrogels; Injections, Intralesional; Liver Neoplasms; Male; Mechanical Phenomena; Mice; Paclitaxel; Polyvinyl Alcohol; Rheology; Temperature | 2016 |
Redox-Sensitive Micelles Based on O,N-Hydroxyethyl Chitosan-Octylamine Conjugates for Triggered Intracellular Delivery of Paclitaxel.
Topics: Amines; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Oxidation-Reduction; Paclitaxel; Particle Size; Polymers | 2016 |
Multifunctional near-infrared light-triggered biodegradable micelles for chemo- and photo-thermal combination therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzyl Alcohols; Breast Neoplasms; Chitosan; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Compounding; Drug Stability; Female; Fluorescent Dyes; Humans; Indoles; Infrared Rays; Integrin alphaVbeta3; MCF-7 Cells; Mice, Nude; Micelles; Paclitaxel; Peptides, Cyclic; Photochemotherapy; Photolysis; Propionates; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Paclitaxel-loaded chitosan oligosaccharide-stabilized gold nanoparticles as novel agents for drug delivery and photoacoustic imaging of cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Drug Stability; Gold; Humans; Metal Nanoparticles; Oligosaccharides; Paclitaxel; Particle Size; Photoacoustic Techniques | 2016 |
Heparin modification enhances the delivery and tumor targeting of paclitaxel-loaded N-octyl-N-trimethyl chitosan micelles.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Delivery Systems; HeLa Cells; Heparin; Humans; Male; Mice; Micelles; NIH 3T3 Cells; Paclitaxel; Rats; Rats, Sprague-Dawley | 2016 |
Transferrin functionalized chitosan-PEG nanoparticles for targeted delivery of paclitaxel to cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Chitosan; Drug Delivery Systems; Humans; Lung Neoplasms; Microscopy, Fluorescence; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Receptors, Transferrin; Spectroscopy, Fourier Transform Infrared; Tissue Distribution; Transferrin | 2016 |
Paclitaxel loaded magnetic nanocomposites with folate modified chitosan/carboxymethyl surface; a vehicle for imaging and targeted drug delivery.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Chitosan; Drug Delivery Systems; Drug Liberation; Erythrocytes; Ferric Compounds; Folic Acid; Hemolysis; Humans; Magnetic Phenomena; MCF-7 Cells; Nanocomposites; Neoplasms; Nickel; Paclitaxel; Serum Albumin, Bovine | 2016 |
Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier.
Topics: Adsorption; Antineoplastic Agents; Breast Neoplasms; Cell Cycle Checkpoints; Cell Survival; Chitosan; Disulfides; Drug Compounding; Drug Liberation; Female; Gene Transfer Techniques; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Nanoconjugates; Nanomedicine; Oxazines; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; RNAi Therapeutics; Static Electricity; Stearic Acids; Surface Properties; Time Factors; Transfection | 2016 |
Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Chitosan; Drug Carriers; Epithelial Cells; Humans; Ileum; Intestinal Absorption; Male; Mice; Nanoparticles; Paclitaxel; Rats; Rats, Wistar; Solubility; Tight Junctions; Verapamil; Water | 2016 |
Novel amphiphilic folic acid-cholesterol-chitosan micelles for paclitaxel delivery.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Cholesterol; Drug Liberation; Folic Acid; Humans; Hydrogen-Ion Concentration; Micelles; Paclitaxel; Particle Size; Proton Magnetic Resonance Spectroscopy | 2017 |
Co-delivery of antineoplastic and protein drugs by chitosan nanocapsules for a collaborative tumor treatment.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chitosan; HeLa Cells; Humans; Inhibitory Concentration 50; Nanocapsules; Paclitaxel | 2017 |
Specific targeting delivery to MUC1 overexpressing tumors by albumin-chitosan nanoparticles conjugated to DNA aptamer.
Topics: Aptamers, Nucleotide; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Humans; MCF-7 Cells; Molecular Targeted Therapy; Mucin-1; Nanoparticles; Paclitaxel; Serum Albumin | 2016 |
Targeting Taxanes to Castration-Resistant Prostate Cancer Cells by Nanobubbles and Extracorporeal Shock Waves.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Chitosan; Docetaxel; Drug Carriers; Drug Liberation; High-Energy Shock Waves; Humans; Male; Nanostructures; Paclitaxel; Particle Size; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2016 |
Synthesis and characterization of chitosan-grafted-polycaprolactone micelles for modulate intestinal paclitaxel delivery.
Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Survival; Chitosan; Drug Carriers; HT29 Cells; Humans; Intestinal Mucosa; Micelles; Paclitaxel; Polyesters | 2018 |
Investigation of graphene-based nanomaterial as nanocarrier for adsorption of paclitaxel anticancer drug: a molecular dynamics simulation study.
Topics: Adsorption; Antineoplastic Agents; Chitosan; Drug Delivery Systems; Graphite; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Nanostructures; Oxides; Paclitaxel; Surface Properties | 2017 |
Physicochemical characterization of chitosan-hyaluronan-coated solid lipid nanoparticles for the targeted delivery of paclitaxel: a proof-of-concept study in breast cancer cells.
Topics: Breast Neoplasms; Cell Survival; Chitosan; Drug Delivery Systems; Drug Stability; Female; Humans; Hyaluronic Acid; Lipids; MCF-7 Cells; Nanoparticles; Paclitaxel | 2017 |
Enhanced apoptotic and anticancer potential of paclitaxel loaded biodegradable nanoparticles based on chitosan.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Humans; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols | 2017 |
Trimethyl chitosan based conjugates for oral and intravenous delivery of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Delayed-Action Preparations; Diffusion; Female; Folate Receptors, GPI-Anchored; Folic Acid; Hydrogen-Ion Concentration; Injections, Intravenous; Mice; Molecular Targeted Therapy; Nanocapsules; Nanoconjugates; Neoplasms, Experimental; Paclitaxel; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2017 |
Vitamin E Succinate-Grafted-Chitosan Oligosaccharide/RGD-Conjugated TPGS Mixed Micelles Loaded with Paclitaxel for U87MG Tumor Therapy.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Drug Carriers; Glioma; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Oligopeptides; Oligosaccharides; Paclitaxel; Particle Size; Succinates; Vitamin E | 2017 |
Development of drug-loaded chitosan hollow nanoparticles for delivery of paclitaxel to human lung cancer A549 cells.
Topics: A549 Cells; Antineoplastic Agents; Biological Availability; Calorimetry, Differential Scanning; Cell Survival; Chitosan; Drug Delivery Systems; Humans; Lung; Lung Neoplasms; Nanoparticles; Nanospheres; Paclitaxel; X-Ray Diffraction | 2017 |
Adaptive Chitosan Hollow Microspheres as Efficient Drug Carrier.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Line; Chitosan; Drug Carriers; Fibroblasts; Hep G2 Cells; Humans; Mice; Microspheres; Paclitaxel | 2017 |
Tumor Microenvironment Responsive Nanogel for the Combinatorial Antitumor Effect of Chemotherapy and Immunotherapy.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Drug Carriers; Drug Delivery Systems; Gels; Humans; Immunotherapy; Interleukin-2; Mice, Inbred C57BL; Neoplasms; Paclitaxel; Rats, Sprague-Dawley; Tumor Microenvironment | 2017 |
In vivo antitumor effect of endostatin-loaded chitosan nanoparticles combined with paclitaxel on Lewis lung carcinoma.
Topics: Animals; Carcinoma, Lewis Lung; Cell Line, Tumor; Chitosan; Endostatins; Mice; Mice, Inbred C57BL; Nanoparticles; Paclitaxel; Vascular Endothelial Growth Factor A | 2017 |
A Bimetallic Silver-Neodymium Theranostic Nanoparticle with Multimodal NIR/MRI/CT Imaging and Combined Chemo-photothermal Therapy.
Topics: Ablation Techniques; Antineoplastic Agents; Chitosan; Contrast Media; Drug Carriers; Drug Liberation; Green Chemistry Technology; Heating; HeLa Cells; Humans; Magnetic Resonance Imaging; Metal Nanoparticles; Multimodal Imaging; Neodymium; Optical Imaging; Paclitaxel; Particle Size; Silver; Theranostic Nanomedicine; Tomography, X-Ray Computed | 2017 |
N-Deoxycholic acid-N,O-hydroxyethyl Chitosan with a Sulfhydryl Modification To Enhance the Oral Absorptive Efficiency of Paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chitosan; Deoxycholic Acid; Drug Carriers; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Micelles; Models, Animal; Paclitaxel; Permeability; Rats; Rhodamine 123; Sulfhydryl Compounds; Tight Junctions | 2017 |
1, 3β-Glucan anchored, paclitaxel loaded chitosan nanocarrier endows enhanced hemocompatibility with efficient anti-glioblastoma stem cells therapy.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Liberation; Glucans; Hemolysis; Humans; Nanoparticles; Paclitaxel | 2018 |
Paclitaxel and quercetin nanoparticles co-loaded in microspheres to prolong retention time for pulmonary drug delivery.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chitosan; Drug Delivery Systems; Drug Liberation; Female; Half-Life; Lung; Male; Microspheres; Nanoparticles; Oleic Acid; Paclitaxel; Particle Size; Quercetin; Rats, Wistar; Tissue Distribution | 2017 |
N-mercapto acetyl-N'-octyl-O, N″-glycol chitosan as an efficiency oral delivery system of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Chitosan; Drug Carriers; Endocytosis; Humans; Intestinal Mucosa; Micelles; Paclitaxel; Particle Size; Rats, Sprague-Dawley; Tight Junctions; Verapamil | 2018 |
Mucus adhesion- and penetration-enhanced liposomes for paclitaxel oral delivery.
Topics: Administration, Oral; Animals; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Gastrointestinal Tract; Intestinal Absorption; Intestinal Mucosa; Liposomes; Paclitaxel; Particle Size; Permeability; Poloxamer; Solubility; Swine; Thioglycolates | 2018 |
New Folate-Grafted Chitosan Derivative To Improve Delivery of Paclitaxel-Loaded Solid Lipid Nanoparticles for Lung Tumor Therapy by Inhalation.
Topics: Administration, Inhalation; Albumins; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Lipids; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Polyethylene Glycols; Surface Properties; Tissue Distribution; Xenograft Model Antitumor Assays | 2018 |
CD44-Targeted Facile Enzymatic Activatable Chitosan Nanoparticles for Efficient Antitumor Therapy and Reversal of Multidrug Resistance.
Topics: alpha-Tocopherol; Animals; Chitosan; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hyaluronan Receptors; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasm Proteins; Neoplasms; NIH 3T3 Cells; Paclitaxel; Xenograft Model Antitumor Assays | 2018 |
MHI-148 Cyanine Dye Conjugated Chitosan Nanomicelle with NIR Light-Trigger Release Property as Cancer Targeting Theranostic Agent.
Topics: Animals; Carbocyanines; Cell Line; Chitosan; Coloring Agents; Coumarins; Humans; Hyperthermia, Induced; Light; Mice, Inbred BALB C; Mice, Nude; Micelles; Nanoparticles; Neoplasms; Paclitaxel; Phototherapy; Spectroscopy, Near-Infrared; Theranostic Nanomedicine; Thiazoles; Tissue Distribution | 2018 |
Effects of Paclitaxel-conjugated N-Succinyl-Hydroxyethyl Chitosan Film for Proliferative Cholangitis in Rabbit Biliary Stricture Model.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Chitosan; Cholangitis; Drug Carriers; Humans; Magnetic Resonance Spectroscopy; Membranes, Artificial; Paclitaxel; Rabbits; Spectroscopy, Fourier Transform Infrared | 2018 |
Understanding the co-loading and releasing of doxorubicin and paclitaxel using chitosan functionalized single-walled carbon nanotubes by molecular dynamics simulations.
Topics: Antineoplastic Agents; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Liberation; Humans; Molecular Dynamics Simulation; Nanotubes, Carbon; Paclitaxel; Surface Properties; Thermodynamics | 2018 |
Application of a simple desolvation method to increase the formation yield, physical stability and hydrophobic drug encapsulation capacity of chitosan-based nanoparticles.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Buffers; Cell Survival; Chitosan; Culture Media; Drug Carriers; Drug Compounding; Drug Stability; Female; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Molecular Dynamics Simulation; Nanoparticles; Nanotechnology; Paclitaxel; Technology, Pharmaceutical | 2018 |
PTX-loaded three-layer PLGA/CS/ALG nanoparticle based on layer-by-layer method for cancer therapy.
Topics: Alginates; Antineoplastic Agents; Apoptosis; Biocompatible Materials; Biological Transport; Cell Survival; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Nanoparticles; Paclitaxel; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents | 2018 |
Biodegradable Alginate-Chitosan Hollow Nanospheres for Codelivery of Doxorubicin and Paclitaxel for the Effect of Human Lung Cancer A549 Cells.
Topics: A549 Cells; Alginates; Chitosan; Doxorubicin; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; Humans; Lung Neoplasms; Nanospheres; Paclitaxel | 2018 |
[pH-sensitive micelles loaded paclitaxel using carboxymethyl chitosan-palmitic acid mediated by cRGD].
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Chitosan; Drug Carriers; Drug Liberation; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Oligopeptides; Paclitaxel; Palmitic Acid; Particle Size; Polymers; Spectroscopy, Fourier Transform Infrared | 2016 |
Polymeric Micelles Based on Modified Glycol Chitosan for Paclitaxel Delivery: Preparation, Characterization and Evaluation.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Chitosan; Drug Delivery Systems; Female; Glycerol; Humans; Injections, Intravenous; Male; MCF-7 Cells; Mice; Micelles; Paclitaxel; Particle Size; Polymers; Proton Magnetic Resonance Spectroscopy; Rabbits; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction | 2018 |
Paclitaxel delivery system based on poly(lactide-co-glycolide) microparticles and chitosan thermo-sensitive gel for mammary adenocarcinoma treatment.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Female; Gels; Kinetics; Mammary Neoplasms, Animal; Mice, Inbred BALB C; Paclitaxel; Particle Size; Polyglactin 910; Temperature; Tumor Burden | 2018 |
Amphiphilic Polymeric Micelles Based on Deoxycholic Acid and Folic Acid Modified Chitosan for the Delivery of Paclitaxel.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Deoxycholic Acid; Drug Carriers; Female; Folic Acid; Humans; Injections, Intravenous; Liver Neoplasms; MCF-7 Cells; Mice; Micelles; Neoplasm Transplantation; Paclitaxel; Particle Size; Xenograft Model Antitumor Assays | 2018 |
Hexa-functional tumour-seeking nano voyagers and annihilators for synergistic cancer theranostic applications.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; NIH 3T3 Cells; Paclitaxel; Theranostic Nanomedicine; Transplantation, Heterologous | 2018 |
Acylated chitosan anchored paclitaxel loaded liposomes: Pharmacokinetic and biodistribution study in Ehrlich ascites tumor bearing mice.
Topics: A549 Cells; Acylation; Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Chitosan; Humans; Liposomes; Mice; Paclitaxel; Tissue Distribution | 2019 |
Preparation and evaluation of carboxymethyl chitosan-rhein polymeric micelles with synergistic antitumor effect for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Drug Synergism; Humans; Male; Mice, Inbred ICR; Micelles; Neoplasms; Paclitaxel; Verapamil | 2019 |
Self-assembled micelles based on N-octyl-N'-phthalyl-O-phosphoryl chitosan derivative as an effective oral carrier of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Down-Regulation; Drug Carriers; Drug Liberation; Endocytosis; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Fluidity; Mice, Inbred BALB C; Micelles; Paclitaxel; Rats, Sprague-Dawley; Solubility; Transcytosis; Verapamil | 2019 |
Self-Assembled Reduced Albumin and Glycol Chitosan Nanoparticles for Paclitaxel Delivery.
Topics: Animals; Antineoplastic Agents; Cattle; Chitosan; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Endocytosis; HeLa Cells; Humans; Nanoparticles; Oxidation-Reduction; Paclitaxel; Serum Albumin, Bovine | 2019 |
Improving antitumor outcomes for palliative intratumoral injection therapy through lecithin- chitosan nanoparticles loading paclitaxel- cholesterol complex.
Topics: Animals; Antineoplastic Agents; Apoptosis; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chitosan; Cholesterol; Drug Liberation; Endocytosis; Injections, Intralesional; Lecithins; Liver; Lung; Mice, Inbred BALB C; Nanoparticles; Neoplasm Recurrence, Local; Paclitaxel; Palliative Care; Particle Size; Polysorbates; Survival Analysis; Treatment Outcome | 2019 |
Redox-sensitive micelles based on retinoic acid modified chitosan conjugate for intracellular drug delivery and smart drug release in cancer therapy.
Topics: Antineoplastic Agents; Cell Survival; Chitosan; Cystamine; Drug Carriers; Drug Liberation; Hep G2 Cells; Humans; Micelles; Neoplasms; Oxidation-Reduction; Paclitaxel; Particle Size; Tretinoin | 2019 |
Simultaneous controlled release of 5-FU, DOX and PTX from chitosan/PLA/5-FU/g-C3N4-DOX/g-C3N4-PTX triaxial nanofibers for breast cancer treatment in vitro.
Topics: Breast Neoplasms; Cell Adhesion; Cell Survival; Chitosan; Delayed-Action Preparations; Doxorubicin; Drug Liberation; Female; Fluorouracil; Graphite; Humans; Kinetics; MCF-7 Cells; Nanofibers; Nitriles; Paclitaxel; Polyesters; X-Ray Diffraction | 2019 |
Dual-responsive nanoparticles based on chitosan for enhanced breast cancer therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Ethylene Glycols; Female; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Methacrylates; Mice; Nanoparticles; Paclitaxel; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2019 |
Anti-EGFR antibody conjugated thiol chitosan-layered gold nanoshells for dual-modal imaging-guided cancer combination therapy.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Combined Modality Therapy; Diagnostic Imaging; Drug Liberation; ErbB Receptors; Erythrocytes; Female; Gold; Humans; Mice, Inbred BALB C; Mice, Nude; Nanoshells; Neoplasms; Paclitaxel; Photoacoustic Techniques; Sulfhydryl Compounds; Theranostic Nanomedicine | 2019 |
Synthesis of magnetic gold coated poly (ε-caprolactonediol) based polyurethane/poly(N-isopropylacrylamide)-grafted-chitosan core-shell nanofibers for controlled release of paclitaxel and 5-FU.
Topics: Acrylic Resins; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Female; Fluorouracil; Gold; Magnetic Iron Oxide Nanoparticles; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Nanofibers; Paclitaxel; Polyesters; Polyurethanes | 2020 |
Evaluation of intestinal permeation enhancement with carboxymethyl chitosan-rhein polymeric micelles for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Chitosan; Disease Models, Animal; Drug Carriers; Drug Compounding; Humans; Intestinal Mucosa; Male; Mice; Micelles; Neoplasms; Paclitaxel; Permeability; Rats; Tissue Distribution; Verapamil | 2020 |
Polylysine and cysteine functionalized chitosan nanoparticle as an efficient platform for oral delivery of paclitaxel.
Topics: Administration, Oral; Animals; Caco-2 Cells; Chitosan; Cysteine; Drug Carriers; Humans; Mice; Nanoparticles; Paclitaxel; Polylysine; Rats; Rats, Sprague-Dawley; Tissue Distribution; Xenograft Model Antitumor Assays | 2020 |
Anisamide-functionalized pH-responsive amphiphilic chitosan-based paclitaxel micelles for sigma-1 receptor targeted prostate cancer treatment.
Topics: Animals; Chitosan; Delayed-Action Preparations; Drug Carriers; Gene Expression Regulation, Neoplastic; Hemolysis; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Male; Materials Testing; Mice; Micelles; Molecular Targeted Therapy; Paclitaxel; PC-3 Cells; Prostatic Neoplasms; Receptors, sigma; Sigma-1 Receptor; Xenograft Model Antitumor Assays | 2020 |
Multi-functional chitosan polymeric micelles as oral paclitaxel delivery systems for enhanced bioavailability and anti-tumor efficacy.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Micelles; Paclitaxel; Polymers; Rats; Solubility | 2020 |
An Automatable Hydrogel Culture Platform for Evaluating Efficacy of Antibody-Based Therapeutics in Overcoming Chemoresistance.
Topics: A549 Cells; Aldehyde Dehydrogenase, Mitochondrial; Alginates; Antineoplastic Agents, Immunological; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chitosan; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Heme Oxygenase-1; High-Throughput Screening Assays; Humans; Hydrogels; Male; Neoplasms; Paclitaxel; Proteomics | 2020 |
Novel Chitosan Derivatives with Reversible Cationization and Hydrophobicization for Tumor Cytoplasm-Specific Burst Co-delivery of siRNA and Chemotherapeutics.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Cations; Chitosan; Cytoplasm; Drug Carriers; Female; Glutathione; Humans; Hyaluronic Acid; Mice; Mice, Nude; Micelles; Neoplasms; Paclitaxel; Particle Size; Polyethyleneimine; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2020 |
Polyelectrolyte three layer nanoparticles of chitosan/dextran sulfate/chitosan for dual drug delivery.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Chitosan; Dextran Sulfate; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Fluorouracil; Hep G2 Cells; Humans; Nanoparticles; Paclitaxel; Particle Size; Polyelectrolytes; Surface Properties | 2020 |
Glycol chitosan in situ coating on PLGA nanoparticle curtails extraneous paclitaxel precipitates and imparts protein corona independent hemocompatibility.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemical Precipitation; Chitosan; Drug Liberation; Erythrocytes; Goats; Humans; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Corona; Rats | 2020 |
l-Carnitine conjugated chitosan-stearic acid polymeric micelles for improving the oral bioavailability of paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Carnitine; Chitosan; Drug Carriers; Drug Liberation; Female; Humans; Intestinal Absorption; Male; Micelles; Paclitaxel; Particle Size; Rats, Sprague-Dawley; Solute Carrier Family 22 Member 5; Stearic Acids | 2020 |
Design and evaluation of the anticancer activity of paclitaxel-loaded anisotropic-poly(lactic-co-glycolic acid) nanoparticles with PEGylated chitosan surface modifications.
Topics: Antineoplastic Agents; Chitosan; Drug Design; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Nanoparticles; Neoplasms; Paclitaxel; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Immobilization of Paclitaxel on Hydroxyapatite for Breast Cancer Investigations.
Topics: Breast Neoplasms; Cell Survival; Chitosan; Durapatite; Female; Humans; Nanoparticles; Paclitaxel | 2020 |
Fabrication of poly(acrylic acid) grafted-chitosan/polyurethane/magnetic MIL-53 metal organic framework composite core-shell nanofibers for co-delivery of temozolomide and paclitaxel against glioblastoma cancer cells.
Topics: Acrylic Resins; Cell Line, Tumor; Chitosan; Glioblastoma; Humans; Magnetic Phenomena; Metal-Organic Frameworks; Nanofibers; Paclitaxel; Polyurethanes; Temozolomide | 2020 |
Synthesis of PLGA/chitosan/zeolites and PLGA/chitosan/metal organic frameworks nanofibers for targeted delivery of Paclitaxel toward prostate cancer cells death.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Male; Metal-Organic Frameworks; Microscopy, Electron, Scanning; Nanofibers; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction; Zeolites | 2020 |
Engineering the pH-Sensitivity of the Graphene and Carbon Nanotube Based Nanomedicines in Smart Cancer Therapy by Grafting Trimetyl Chitosan.
Topics: Adsorption; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Graphite; Hydrogen Bonding; Hydrogen-Ion Concentration; Nanomedicine; Nanotubes, Carbon; Paclitaxel; Static Electricity | 2020 |
A targeted and redox/pH-responsive chitosan oligosaccharide derivatives based nanohybrids for overcoming multidrug resistance of breast cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Chitosan; Drug Carriers; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Folic Acid; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Nanoparticles; Oxidation-Reduction; Paclitaxel; Polyethyleneimine; RNA, Small Interfering | 2021 |
Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chitosan; Lung Neoplasms; Nanoparticles; Paclitaxel; Prospective Studies; Quercetin | 2021 |
Chitosan oligosaccharide modified liposomes enhance lung cancer delivery of paclitaxel.
Topics: A549 Cells; Animals; Antineoplastic Agents; Chitosan; Drug Carriers; Drug Liberation; Humans; Liposomes; Lung; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Oligosaccharides; Paclitaxel | 2021 |
Paclitaxel-Loaded Magnetic Nanoparticles Based on Biotinylated
Topics: Antineoplastic Agents, Phytogenic; Biotin; Cell Line, Tumor; Chitosan; Colloids; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Magnetite Nanoparticles; MCF-7 Cells; Paclitaxel; Polymers | 2021 |
A pH-Sensitive Polymeric Micellar System Based on Chitosan Derivative for Efficient Delivery of Paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Drug Liberation; Humans; MCF-7 Cells; Micelles; Neoplasms; Paclitaxel; Particle Size; Polymers | 2021 |
Loading and release of cancer chemotherapy drugs utilizing simultaneous temperature and pH-responsive nanohybrid.
Topics: Acrylamides; Adsorption; Antineoplastic Agents; Chitosan; Doxorubicin; Drug Carriers; Drug Liberation; Hydrogen Bonding; Hydrogen-Ion Concentration; Nanotubes, Carbon; Paclitaxel; Particle Size; Temperature | 2021 |
AIE-active polymeric micelles based on modified chitosan for bioimaging-guided targeted delivery and controlled release of paclitaxel.
Topics: Animals; Antineoplastic Agents; Carbohydrate Sequence; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Female; Fluorescent Dyes; Humans; Mice; Micelles; Neoplasms; Paclitaxel | 2021 |
Enhanced antitumor efficacy of glutathione-responsive chitosan based nanoparticles through co-delivery of chemotherapeutics, genes, and immune agents.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Female; Glutathione; Humans; Interleukin-2; Mice; Nanoparticles; Neoplasms; Paclitaxel; RNA, Small Interfering; Survivin | 2021 |
pH responsive release of paclitaxel by self-assembling Chitosan-ethyl vanillin@GNRs nanocomposites.
Topics: Benzaldehydes; Chitosan; Hydrogen-Ion Concentration; Nanocomposites; Paclitaxel; Spectroscopy, Fourier Transform Infrared | 2021 |
Effect of targeting ligand designation of self-assembly chitosan-poloxamer nanogels loaded Paclitacel on inhibiting MCF-7 cancer cell growth.
Topics: Cell Line, Tumor; Chitosan; Drug Carriers; Folic Acid; Humans; Ligands; MCF-7 Cells; Nanogels; Nanoparticles; Neoplasms; Paclitaxel; Poloxamer | 2022 |
Folic Acid and Chitosan-Functionalized Gold Nanorods and Triangular Silver Nanoplates for the Delivery of Anticancer Agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Chitosan; Docetaxel; Folic Acid; G2 Phase Cell Cycle Checkpoints; Gold; HeLa Cells; Humans; Metal Nanoparticles; Nanotubes; Paclitaxel; Silver | 2022 |
Design and fabrication of chitosan-based AIE active micelles for bioimaging and intelligent delivery of paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Micelles; Paclitaxel; Polymers | 2022 |
Polysaccharide-coated porous starch-based oral carrier for paclitaxel: Adsorption and sustained release in colon.
Topics: Adsorption; Chitosan; Colon; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Excipients; Microspheres; Paclitaxel; Phytic Acid; Porosity; Starch | 2022 |
Biomimetic and temporal-controlled nanocarriers with ileum transporter targeting for achieving oral administration of chemotherapeutic drugs.
Topics: Administration, Oral; Biomimetics; Chitosan; Drug Carriers; Humans; Ileum; Nanoparticles; Oligosaccharides; Paclitaxel; Quercetin | 2022 |
Synchronizing the release rates of topotecan and paclitaxel from a self-eroding crosslinked chitosan - PLGA platform.
Topics: Calcium Chloride; Chitosan; Hydrogels; Paclitaxel; Topotecan; Water | 2022 |
Evaluation and antitumor mechanism of functionalized chitosan-based polymeric micelles for oral delivery of paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Line, Tumor; Chitosan; Drug Carriers; Humans; Mice; Micelles; Paclitaxel; Polymers; Receptors, Antigen, T-Cell; Zebrafish | 2022 |
Engineered Magnetic Polymer Nanoparticles Can Ameliorate Breast Cancer Treatment Inducing Pyroptosis-Starvation along with Chemotherapy.
Topics: Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Emulsions; Female; Glucose Oxidase; Humans; Magnetic Phenomena; Nanoparticles; Paclitaxel; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyroptosis; Solvents | 2022 |
Preparation of Paclitaxel-Encapsulated Bio-Functionalized Selenium Nanoparticles and Evaluation of Their Efficacy against Cervical Cancer.
Topics: Cell Line, Tumor; Chitosan; Female; Humans; Nanoparticles; Paclitaxel; Selenium; Uterine Cervical Neoplasms | 2022 |
Tumor targeted delivery of mycobacterial adjuvant encapsulated chitosan nanoparticles showed potential anti-cancer activity and immune cell activation in tumor microenvironment.
Topics: Adjuvants, Immunologic; Animals; Cell Line, Tumor; Chitosan; Mice; Nanoparticles; Paclitaxel; Tumor Microenvironment | 2023 |
Tumor Targeting and pH-Sensitive Inclusion Complex Based on HP-β-CD as a Potential Carrier for Paclitaxel: Fabrication, Molecular Docking, and Characterization.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Drug Carriers; Excipients; Folic Acid; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Neoplasms; Paclitaxel | 2023 |
Paclitaxel-loaded liposome-incorporated chitosan (core)/poly(ε-caprolactone)/chitosan (shell) nanofibers for the treatment of breast cancer.
Topics: Breast Neoplasms; Chitosan; Female; Humans; Liposomes; Nanofibers; Paclitaxel; Polyesters | 2023 |
Magnetic nanoparticle embedded chitosan-based polymeric network for the hydrophobic drug delivery of paclitaxel.
Topics: Chitosan; Drug Carriers; Drug Liberation; Magnetite Nanoparticles; Nanoparticles; Paclitaxel; Polymers; Spectroscopy, Fourier Transform Infrared | 2023 |
The effect of chitosan hydrogel containing gold nanoparticle complex with paclitaxel on colon cancer cell line.
Topics: Cell Line, Tumor; Chitosan; Colonic Neoplasms; Gold; Humans; Hydrogels; Metal Nanoparticles; Nanoparticles; Paclitaxel | 2023 |