chitosan has been researched along with mesalamine in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 7 (19.44) | 29.6817 |
| 2010's | 22 (61.11) | 24.3611 |
| 2020's | 6 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, T; Muranishi, S; Odoriba, T; Okabe, S; Terabe, A; Tozaki, H; Yamamoto, A | 1 |
| Fujita, T; Muranishi, S; Odoriba, T; Okabe, S; Okada, N; Suzuki, T; Terabe, A; Tozaki, H; Yamamoto, A | 1 |
| Chen, JH; Chen, ZL; Guo, D; Li, GF; Liu, LJ; Xu, ZY; Yan, Y | 1 |
| Golafshan, S; Jaffarian Dehkordi, A; Varshosaz, J | 1 |
| Dodov, MG; Goracinova, K; Janevik, EI; Kavrakovski, Z; Mladenovska, K; Pavlova, MJ; Raicki, RS; Ristoski, T | 1 |
| Belamie, E; Benoit, JP; Cruaud, O; Goracinova, K; Mladenovska, K; Popovski, E; Raicki, RS; Richomme, P; Venier-Julienne, MC | 1 |
| Downie, J; Elson, CM; Henderson, S; Jordan, JL; Kydonieus, A; Lee, TD; Zhou, J | 1 |
| Huanbutta, K; Limmatvapirat, S; Luangtana-anan, M; Nunthanid, J; Puttipipatkhachorn, S; Sriamornsak, P | 1 |
| Dubey, R; Jain, SK; Omrey, P; Vyas, SP | 1 |
| Carda, C; Diez-Sales, O; Fadda, AM; Loy, G; Manconi, M; Merino, V; Merino-Sanjuan, M; Mura, C; Nácher, A; Ruiz, A | 1 |
| Chen, C; Chen, J; Gao, C; Lii, S; Liu, M | 1 |
| Díez-Sales, O; Fadda, AM; Loy, G; Manconi, M; Merino, V; Merino-Sanjuán, M; Mura, C; Nácher, A | 1 |
| Bautzová, T; Béduneau, A; Lamprecht, A; Pellequer, Y; Rabišková, M | 1 |
| Bostan, MS; Cig, T; Eroglu, MS; Goren, AC; Ozturk, T; Peker, I; Senol, M | 1 |
| Mallipeddi, R; Neau, SH; Omwancha, WS; Valle, BL | 1 |
| Rana, V; Singh, K; Suri, R; Tiwary, AK | 1 |
| Bawa, P; Choonara, YE; du Toit, LC; Kumar, P; Meyer, LC; Ndesendo, VM; Pillay, V | 1 |
| Wu, QX; Yao, SJ | 1 |
| Chen, C; Cui, G; Gao, C; L, S; Liu, M; Ma, S; Wang, J; Yu, C | 1 |
| Alcântara, AC; Aranda, P; Araújo-Moreira, FM; Darder, M; Ribeiro, LN; Ruiz-Hitzky, E | 1 |
| Lakshmanan, P; Newton, AM | 1 |
| Dvořáčková, K; Kejdušová, M; Kubánková, R; Vetchý, D; Vysloužil, J | 1 |
| Bourbon, AI; Cerqueira, MA; Pinheiro, AC; Rivera, MC; Vicente, AA | 1 |
| Bai, X; Duan, H; Gao, C; Liu, M; Lü, S; Qin, H; Wei, Y; Wu, X | 1 |
| Bai, X; Duan, H; Gao, C; Liu, M; Liu, Z; Lü, S; Qin, H; Wei, Y; Wu, X; Zhang, X | 1 |
| Nunes, LCC; Santana, ACSGV; Silva Filho, ECD; Sobrinho, JLS | 1 |
| Babanejad, N; Dorkoosh, FA; Mirabbasi, F; Moghimi, A; Seifirad, S; Shahsavari, S | 1 |
| Gan, N; Gan, R; Li, H; Pu, H; Sun, Q; Tang, P; Yang, H; Zhang, S; Zhao, L | 1 |
| Chen, J; Chen, Y; Cheng, XD; Su, T; Wu, QX; Zhao, J | 1 |
| Lakshmanan, P; Newton, AMJ | 1 |
| Cosco, D; Costa, N; Francardi, M; Fresta, M; Molinaro, R; Palma, E; Paolino, D | 1 |
| Alves, VMO; Cunha, AP; Egito, ESTD; Lima, MN; Melo, CO; Oliveira, EE; Ricardo, NMPS; Souza, E; Urtiga, SCDC | 1 |
| Hoang, HT; Jo, SH; Lim, KT; Oh, CW; Park, H; Park, SH; Phan, QT | 1 |
| Dushkin, AV; Jin, K; Polyakov, NE; Pu, F; Su, W; Xie, Z; Xu, W; Xue, Z | 1 |
| Cerea, M; Dubuquoy, C; Dubuquoy, L; Foppoli, A; Gazzaniga, A; Maroni, A; Moutaharrik, S; Neut, C; Palugan, L; Siepmann, F; Siepmann, J | 1 |
| Bitaraf, FS; Hassani, MS; Mahami, S; Mehrabi, M; Omri, A; Salehi, M; Vahedi, H | 1 |
36 other study(ies) available for chitosan and mesalamine
| Article | Year |
|---|---|
Validation of a pharmacokinetic model of colon-specific drug delivery and the therapeutic effects of chitosan capsules containing 5-aminosalicylic acid on 2,4,6-trinitrobenzenesulphonic acid-induced colitis in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Chitin; Chitosan; Colitis; Colon; Disease Models, Animal; Drug Carriers; Male; Mesalamine; Models, Biological; Rats; Rats, Wistar; Reproducibility of Results; Sulfasalazine; Trinitrobenzenesulfonic Acid | 1999 |
Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Carboxymethylcellulose Sodium; Chitin; Chitosan; Colitis, Ulcerative; Colon; Drug Carriers; Intestinal Absorption; Male; Mesalamine; Peroxidase; Rats; Rats, Wistar; Tissue Distribution; Trinitrobenzenesulfonic Acid | 2002 |
[Absorption and distribution of 5-aminosalicylic acid from its chitosan capsule degraded by colon bacteria-released enzymes in rats].
Topics: Absorption; Animals; Area Under Curve; Bacteria; Chitin; Chitosan; Chromatography, High Pressure Liquid; Colon; Mesalamine; Rats; Tissue Distribution | 2003 |
Colon-specific delivery of mesalazine chitosan microspheres.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Colon; Drug Carriers; Drug Delivery Systems; Male; Mesalamine; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Rats; Rats, Wistar | 2006 |
Colon-specific delivery of 5-aminosalicylic acid from chitosan-Ca-alginate microparticles.
Topics: Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Body Weight; Calcium; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Chitosan; Colitis; Colon; Crystallography, X-Ray; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Electrochemistry; Excipients; Gels; Magnetic Resonance Spectroscopy; Male; Mesalamine; Microspheres; Organ Size; Particle Size; Peroxidase; Rats; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Tissue Distribution | 2007 |
5-ASA loaded chitosan-Ca-alginate microparticles: Preparation and physicochemical characterization.
Topics: Alginates; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Chitosan; Desiccation; Drug Stability; Electrochemistry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Glucuronic Acid; Hexuronic Acids; Mesalamine; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; X-Ray Diffraction | 2007 |
Use of a sulfated chitosan derivative to reduce bladder inflammation in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitin; Chitosan; Cystitis; Female; Mesalamine; Rats; Rats, Sprague-Dawley | 2007 |
Use of spray-dried chitosan acetate and ethylcellulose as compression coats for colonic drug delivery: effect of swelling on triggering in vitro drug release.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Glucosidase; Cellulose; Chitosan; Colon; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Excipients; Gels; Hydrogen-Ion Concentration; Mesalamine; Solubility; Tablets | 2009 |
Development and characterization of colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride for the treatment of ulcerative colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chitosan; Colitis, Ulcerative; Colon; Drug Carriers; Drug Combinations; Drug Compounding; Drug Delivery Systems; Excipients; Female; Glycine; Male; Mesalamine; Microspheres; Particle Size; Polymethacrylic Acids; Rats; Rats, Mutant Strains; Solubility | 2010 |
N-Succinyl-chitosan systems for 5-aminosalicylic acid colon delivery: in vivo study with TNBS-induced colitis model in rats.
Topics: Absorption; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Colitis; Colon; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Freeze Drying; Intestinal Mucosa; Lymphocyte Activation; Male; Mesalamine; Organ Size; Peroxidase; Polymers; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2011 |
In vitro degradation and drug-release properties of water-soluble chitosan cross-linked oxidized sodium alginate core-shell microgels.
Topics: Administration, Oral; Alginates; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cell Death; Chitosan; Colitis, Ulcerative; Colon; Drug Delivery Systems; Drug Liberation; Electrolytes; Gels; Glucuronic Acid; HEK293 Cells; Hexuronic Acids; Humans; Hydrodynamics; Mesalamine; Oxidation-Reduction; Solutions; Temperature; Water | 2012 |
Design, characterization and in vitro evaluation of 5-aminosalicylic acid loaded N-succinyl-chitosan microparticles for colon specific delivery.
Topics: Biocompatible Materials; Calorimetry, Differential Scanning; Chitosan; Colon; Desiccation; Drug Delivery Systems; Freeze Drying; Humans; Hydrogen-Ion Concentration; Kinetics; Mesalamine; Microscopy, Electron, Scanning; Microspheres; Particle Size; Rheology; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Wettability; X-Ray Diffraction | 2012 |
Bioadhesive pellets increase local 5-aminosalicylic acid concentration in experimental colitis.
Topics: Animals; Anti-Inflammatory Agents; Biopolymers; Chitosan; Colitis; Colon; Drug Delivery Systems; Drug Implants; Hydrogen-Ion Concentration; Inflammation; Male; Mesalamine; Particle Size; Peroxidase; Rats; Rats, Wistar; Solubility | 2012 |
Controlled release of 5-aminosalicylicacid from chitosan based pH and temperature sensitive hydrogels.
Topics: Acrylic Resins; Chitosan; Delayed-Action Preparations; Epoxy Compounds; Hot Temperature; Hydrogels; Mesalamine; Methacrylates | 2013 |
Chitosan as a pore former in coated beads for colon specific drug delivery of 5-ASA.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chitosan; Colon; Drug Carriers; Drug Delivery Systems; Excipients; Male; Mesalamine; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2013 |
Exploiting the synergistic effect of chitosan-EDTA conjugate with MSA for the early recovery from colitis.
Topics: Adhesiveness; Animals; Calorimetry, Differential Scanning; Chitosan; Colitis; Colon; Drug Synergism; Edetic Acid; Hydrogen-Ion Concentration; Mesalamine; Microscopy, Electron, Scanning; Powders; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Tablets; Trinitrobenzenesulfonic Acid | 2013 |
A novel stimuli-synchronized alloy-treated matrix for space-defined gastrointestinal delivery of mesalamine in the Large White pig model.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Barium Sulfate; beta-Glucosidase; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Chitosan; Colon; Cross-Linking Reagents; Drug Carriers; Mesalamine; Microscopy, Electron, Scanning; Molecular Docking Simulation; Pectins; Polygalacturonase; Polyphosphates; Polysaccharides, Bacterial; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties; Swine | 2013 |
Novel NaCS-CS-PPS microcapsules as a potential enzyme-triggered release carrier for highly-loading 5-ASA.
Topics: Cellulose; Chitosan; Drug Carriers; Enzymes; Mesalamine; Polyphosphates; Sodium | 2013 |
Preparation and characterization of OSA/CS core-shell microgel: in vitro drug release and degradation properties.
Topics: Absorbable Implants; Adsorption; Alginates; Chitosan; Drug Carriers; Gels; Glucuronic Acid; Hexuronic Acids; Materials Testing; Mesalamine; Models, Biological; Nanospheres; Oxidation-Reduction; Particle Size; Polymers | 2013 |
Pectin-coated chitosan-LDH bionanocomposite beads as potential systems for colon-targeted drug delivery.
Topics: Chitosan; Colon; Drug Delivery Systems; Hydroxides; Mesalamine; Mucins; Nanocomposites; Pectins | 2014 |
Effect of HPMC - E15 LV premium polymer on release profile and compression characteristics of chitosan/ pectin colon targeted mesalamine matrix tablets and in vitro study on effect of pH impact on the drug release profile.
Topics: Animals; Chitosan; Colon; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Mesalamine; Methylcellulose; Patents as Topic; Pectins; Polymers; Rats; Tablets | 2014 |
[Impact of formulation and process parameters on the properties of chitosan-based microspheres prepared by external ionic gelation].
Topics: Chemistry, Pharmaceutical; Chitosan; Drug Compounding; Mesalamine; Microspheres; Polyphosphates | 2014 |
Hollow chitosan/alginate nanocapsules for bioactive compound delivery.
Topics: Alginates; Caseins; Chitosan; Drug Carriers; Drug Compounding; Drug Liberation; Glucuronic Acid; Hexuronic Acids; Kinetics; Linear Models; Mesalamine; Microscopy, Electron, Transmission; Nanocapsules; Particle Size; Peptide Fragments; Polystyrenes | 2015 |
Mucoadhesive microparticulates based on polysaccharide for target dual drug delivery of 5-aminosalicylic acid and curcumin to inflamed colon.
Topics: Animals; Chitosan; Colitis; Colon; Curcumin; Drug Carriers; Inflammatory Bowel Diseases; Mesalamine; Polymethacrylic Acids; Rats | 2016 |
Co-delivery of zinc and 5-aminosalicylic acid from alginate/N-succinyl-chitosan blend microspheres for synergistic therapy of colitis.
Topics: Administration, Oral; Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Colitis; Disease Models, Animal; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Synergism; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Male; Mesalamine; Microscopy, Electron, Scanning; Microspheres; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Zinc | 2017 |
Obtaining the palygorskite:chitosan composite for modified release of 5-aminosalicylic acid.
Topics: Adsorption; Calorimetry, Differential Scanning; Chitosan; Drug Liberation; Kinetics; Magnesium Compounds; Mesalamine; Models, Theoretical; Silicon Compounds; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; X-Ray Diffraction | 2017 |
Preparation of Mesalamine Nanoparticles Using a Novel Polyurethane- Chitosan Graft Copolymer.
Topics: Chitosan; Diffusion; Drug Carriers; Drug Liberation; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Mesalamine; Nanoparticles; Particle Size; Polymerization; Polyurethanes | 2017 |
Mesalazine/hydroxypropyl-β-cyclodextrin/chitosan nanoparticles with sustained release and enhanced anti-inflammation activity.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Chitosan; Delayed-Action Preparations; Dinoprostone; Drug Carriers; Drug Liberation; HT29 Cells; Humans; Interleukin-8; Mesalamine; Nanoparticles; Nitric Oxide; Solubility | 2018 |
Fabrication of the polyphosphates patched cellulose sulfate-chitosan hydrochloride microcapsules and as vehicles for sustained drug release.
Topics: Capsules; Cellulose; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Liberation; Excipients; Mesalamine; Microscopy, Confocal; Microscopy, Electron, Scanning; Polyphosphates; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Time Factors | 2019 |
Comparative Efficacy of Chitosan, Pectin Based Mesalamine Colon Targeted Drug Delivery Systems on TNBS-induced IBD Model Rats.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Colon; Disease Models, Animal; Drug Delivery Systems; Humans; Inflammatory Bowel Diseases; Mesalamine; Pectins; Rats; Rats, Wistar; Reactive Oxygen Species; Trinitrobenzenesulfonic Acid; Ulcer | 2020 |
Improvement of the therapeutic treatment of inflammatory bowel diseases following rectal administration of mesalazine-loaded chitosan microparticles vs Asamax
Topics: Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Survival; Chitosan; Colitis; Dextran Sulfate; Humans; Inflammatory Bowel Diseases; Mesalamine; Mice; Microspheres; Random Allocation; Treatment Outcome | 2019 |
Xylan microparticles for controlled release of mesalamine: Production and physicochemical characterization.
Topics: Chitosan; Computer Simulation; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Gastrointestinal Tract; Humans; Mesalamine; Models, Biological; Particle Size; Xylans | 2020 |
Dual pH-/thermo-responsive chitosan-based hydrogels prepared using "click" chemistry for colon-targeted drug delivery applications.
Topics: Acrylic Resins; Cell Line; Cell Survival; Chitosan; Click Chemistry; Drug Carriers; Drug Liberation; Humans; Hydrogels; Hydrogen-Ion Concentration; Mesalamine; Porosity; Temperature | 2021 |
Research on Preparation of 5-ASA Colon-Specific Hydrogel Delivery System without Crosslinking Agent by Mechanochemical Method.
Topics: Administration, Oral; Alginates; Animals; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Liberation; Humans; Hydrogels; Hydrogen-Ion Concentration; Intestinal Mucosa; Male; Mesalamine; Mice; Particle Size; Rats | 2021 |
In vitro and in vivo evaluation of a pH-, microbiota- and time-based oral delivery platform for colonic release.
Topics: Animals; Chitosan; Colon; Drug Delivery Systems; Hydrogen-Ion Concentration; Inflammatory Bowel Diseases; Mesalamine; Pectins; Rats; Solubility; Tablets | 2023 |
pH-sensitive HPMCP-chitosan nanoparticles containing 5-aminosalicylic acid and berberine for oral colon delivery in a rat model of ulcerative colitis.
Topics: Animals; Berberine; Chitosan; Colitis, Ulcerative; Hydrogen-Ion Concentration; Mesalamine; Nanoparticles; Rats | 2023 |