chitosan has been researched along with mannitol in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.27) | 18.7374 |
| 1990's | 6 (13.64) | 18.2507 |
| 2000's | 21 (47.73) | 29.6817 |
| 2010's | 12 (27.27) | 24.3611 |
| 2020's | 4 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Nagai, T; Nambu, N; Sawayanagl, Y | 1 |
| Artursson, P; Davis, SS; Illum, L; Lindmark, T | 1 |
| Artursson, P; Schipper, NG; Vårum, KM | 1 |
| de Boer, AG; de Leeuw, BJ; Junginger, HE; Kotzé, AF; Luessen, HL; Verhoef, JC | 1 |
| de Boer, AG; Junginger, HE; Kotzé, AF; Luessen, HL; Verhoef, JC | 1 |
| de Boer, AG; Junginger, HE; Kotzé, AF; Luebetaen, HL; Thanou, MM; Verhoef, JC | 1 |
| de Boer, BG; Junginger, HE; Kotzé, AF; Luessen, HL; Thanou, MM; Verhoef, JC | 1 |
| de Boer, AG; Junginger, HE; Kotzé, AF; Luessen, HL; Scharringhausen, T; Thanou, MM; Verhoef, JC | 1 |
| Cheng, X; Croyle, MA; Sandhu, A; Wilson, JM | 1 |
| Hamman, JH; Kotzé, AF; Stander, M | 1 |
| Angelova, N; Hunkeler, D | 2 |
| Nielsen, HM; Portero, A; Remuñán-López, C | 1 |
| Hamman, JH; Jonker, C; Kotzé, AF | 1 |
| Hamman, JH; Kotzé, AF; Schultz, CM | 1 |
| Chow, LC; Takagi, S; Xu, HH; Zhang, Y | 1 |
| Dale, O; Nilsen, T; Olaussen, G; Skorpen, F; Smidsrød, O; Tvedt, KE; Vårum, KM | 1 |
| Frokjaer, S; Hovgaard, L; Kawashima, Y; Takeuchi, H; van de Weert, M; Velaga, S; Yamamoto, H; Yang, M | 1 |
| Elson, C; Henderson, S; Kydonieus, A; Thanou, M | 1 |
| Charlton, ST; Davis, SS; Illum, L | 1 |
| Dailey, LA; Forbes, B; Grainger, CI; Grenha, A; Martin, GP; Remuñán-López, C; Seijo, B | 1 |
| Grenha, A; Remuñan-López, C; Seijo, B; Serra, C | 1 |
| Bagchi, T; Jogani, V; Mishra, AK; Mishra, P; Misra, A; Shah, P | 2 |
| Simon, CG; Weir, MD; Xu, HH | 1 |
| Bravo-Osuna, I; Chacun, H; Ponchel, G; Vauthier, C | 1 |
| Holappa, J; Järvinen, T; Korjamo, T; Mönkkönen, J; Savolainen, J; Taimisto, S | 1 |
| Chen, L; Guo, Q; Kong, X; Li, X; Qian, Z; Shi, S; Wei, Y; Zhao, X; Zheng, X | 1 |
| Danjo, K; Okamoto, H; Shiraki, K; Watanabe, Y; Yasuda, R | 1 |
| Al-Qadi, S; Carrión-Recio, D; Grenha, A; Remuñán-López, C; Seijo, B | 1 |
| Batista, KA; Fernandes, KF; Lopes, FM; Yamashita, F | 1 |
| Bellich, B; Blasi, P; Borgogna, M; Cesàro, A; Rampino, A | 1 |
| Chatchawalsaisin, J; Kulvanich, P; Sinsuebpol, C | 1 |
| Chen, MX; Wei, BH; Ye, J; Yu, JP; Zhang, JB; Zhang, YJ | 1 |
| Cai, C; Dong, W; Tang, X; Wang, L | 1 |
| Buske, S; Hook, S; Mönckedieck, M; Scherließ, R; Trows, S; Young, K | 1 |
| Dureja, H; Gupta, M; Marwaha, RK | 1 |
| Chopra, M; Dilbaghi, N; Kumar, B; Kumar, R; Kumar, S; Manuja, A; Yadav, SC | 1 |
| Al-Qadi, S; Remuñán-López, C; Taboada, P | 1 |
| Brown, MN; Haggard, WO; Harrison, ZL; Jennings, JA; Pace, LR | 1 |
| Amber Jennings, J; Beenken, KE; Brown, MN; Bumgardner, JD; Haggard, WO; Harrison, ZL; Pace, LR; Smeltzer, MS | 1 |
| Chen, H; Huang, Y; Huang, Z; Pan, X; Wang, G; Zhang, X; Zhao, Z | 1 |
| Baldelli, A; Fathordoobady, F; Guo, Y; Kitts, D; Pratap-Singh, A; Singh, A | 1 |
| Fang, W; Hu, Q; Jiang, Z; Qiao, F; Sun, J | 1 |
44 other study(ies) available for chitosan and mannitol
| Article | Year |
|---|---|
Directly compressed tablets containing chitin or chitosan in addition to mannitol.
Topics: Chemistry, Pharmaceutical; Chitin; Chitosan; Drug Compounding; Excipients; Mannitol; Tablets | 1982 |
Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2).
Topics: Biological Transport; Cell Membrane Permeability; Chitin; Chitosan; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Mannitol; Tumor Cells, Cultured | 1994 |
Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells.
Topics: Acetylation; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Chitin; Chitosan; Diuretics, Osmotic; Humans; Intestinal Absorption; Mannitol; Molecular Weight; Oxidoreductases; Structure-Activity Relationship | 1996 |
Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).
Topics: Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Cell Membrane Permeability; Chitin; Chitosan; Electric Impedance; Epithelial Cells; Glutamates; Humans; Intestinal Absorption; Mannitol; Microscopy, Confocal; Polyethylene Glycols | 1998 |
Chitosan for enhanced intestinal permeability: prospects for derivatives soluble in neutral and basic environments.
Topics: Caco-2 Cells; Chitin; Chitosan; Electric Impedance; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Mannitol; Permeability; Solubility | 1999 |
Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2).
Topics: Biological Transport; Caco-2 Cells; Chitin; Chitosan; Drug Carriers; Electric Conductivity; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Mannitol; Permeability; Pharmaceutical Preparations | 1999 |
Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2).
Topics: Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Cell Membrane Permeability; Chitin; Chitosan; Drug Carriers; Electrophysiology; Humans; Intestinal Mucosa; Mannitol; Polyethylene Glycols | 1999 |
Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.
Topics: Biocompatible Materials; Caco-2 Cells; Cell Survival; Chitin; Chitosan; Dose-Response Relationship, Drug; Drug Delivery Systems; Electric Impedance; Epidermis; Humans; Intestines; Mannitol; Permeability; Solubility; Tight Junctions; Time Factors | 2000 |
Development of novel formulations that enhance adenoviral-mediated gene expression in the lung in vitro and in vivo.
Topics: Adenoviridae; Animals; Biocompatible Materials; Biopolymers; Chemistry, Pharmaceutical; Chitin; Chitosan; Dose-Response Relationship, Drug; Excipients; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Mannitol; Mice; Mice, Inbred BALB C; Transduction, Genetic | 2001 |
Effect of the degree of quaternisation of N-trimethyl chitosan chloride on absorption enhancement: in vivo evaluation in rat nasal epithelia.
Topics: Absorption; Animals; Area Under Curve; Chitin; Chitosan; Diuretics, Osmotic; Drug Carriers; Male; Mannitol; Nasal Mucosa; Rats; Rats, Sprague-Dawley | 2002 |
Stability assessment of chitosan-sodium hexametaphosphate capsules.
Topics: Capsules; Cell Membrane; Chitin; Chitosan; Cross-Linking Reagents; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electrolytes; Hydrogen-Ion Concentration; Kinetics; Mannitol; Phosphates; Salts; Sodium Chloride; Time Factors; Water | 2001 |
The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium.
Topics: Absorption; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Chitin; Chitosan; Excipients; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Glutamic Acid; Humans; Mannitol; Molecular Weight; Mouth Mucosa; Peptides; Permeability; Proteins; Stimulation, Chemical | 2002 |
Intestinal paracellular permeation enhancement with quaternised chitosan: in situ and in vitro evaluation.
Topics: Algorithms; Animals; Chitin; Chitosan; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Magnetic Resonance Spectroscopy; Mannitol; Perfusion; Rats; Rats, Sprague-Dawley | 2002 |
Permeability and stability of chitosan-based capsules: effect of preparation.
Topics: Capsules; Chitin; Chitosan; Dextrans; Drug Compounding; Drug Stability; Excipients; Hardness Tests; Mannitol; Molecular Weight; Permeability; Porosity | 2002 |
N-trimethyl chitosan chloride: optimum degree of quaternization for drug absorption enhancement across epithelial cells.
Topics: Absorption; Adjuvants, Pharmaceutic; Biological Transport; Caco-2 Cells; Carbon Radioisotopes; Chemistry, Pharmaceutical; Chitin; Chitosan; Drug Carriers; Electric Conductivity; Epithelial Cells; Humans; Mannitol; Models, Biological; Nasal Mucosa; Polyethylene Glycols; Polymers; Time Factors | 2003 |
In-situ hardening hydroxyapatite-based scaffold for bone repair.
Topics: Aging; Biocompatible Materials; Bone and Bones; Bone Cements; Bone Substitutes; Chitosan; Durapatite; Fracture Healing; Humans; Mannitol; Materials Testing; Microscopy, Electron, Scanning; Polymers; X-Ray Diffraction | 2006 |
Transepithelial transport of morphine and mannitol in Caco-2 cells: the influence of chitosans of different molecular weights and degrees of acetylation.
Topics: Acetylation; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chitosan; Drug Carriers; Epithelium; Humans; Mannitol; Molecular Weight; Morphine; Structure-Activity Relationship | 2006 |
Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan.
Topics: Administration, Inhalation; Animals; Buffers; Calcitonin; Chitosan; Chromatography, High Pressure Liquid; Drug Stability; Excipients; Mannitol; Powders; Protein Conformation; Salmon; Spectrum Analysis | 2007 |
N-sulfonato-N,O-carboxymethylchitosan: a novel polymeric absorption enhancer for the oral delivery of macromolecules.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Animals; Anticoagulants; Area Under Curve; Biological Transport; Caco-2 Cells; Chitosan; Dextrans; Electric Impedance; Fluorescein-5-isothiocyanate; Heparin, Low-Molecular-Weight; Humans; Intestinal Mucosa; Macromolecular Substances; Male; Mannitol; Molecular Structure; Polymers; Rats; Rats, Wistar; Sulfonic Acids; Sulfur Oxides; Viscosity | 2007 |
Evaluation of bioadhesive polymers as delivery systems for nose to brain delivery: in vitro characterisation studies.
Topics: Adhesiveness; Administration, Intranasal; Animals; Benzofurans; Brain; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Diffusion; Dogs; Drug Carriers; Drug Compounding; Epithelial Cells; Gels; Kinetics; Mannitol; Methylation; Models, Chemical; Molecular Weight; Nasal Mucosa; Pectins; Polymers; Propranolol; Solubility; Tissue Adhesives; Viscosity | 2007 |
Chitosan nanoparticles are compatible with respiratory epithelial cells in vitro.
Topics: Biocompatible Materials; Cell Line; Cell Membrane Permeability; Cell Survival; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Electric Impedance; Epithelial Cells; Humans; Mannitol; Microscopy, Confocal; Nanoparticles; Particle Size; Powders; Respiratory Mucosa | 2007 |
Chitosan nanoparticle-loaded mannitol microspheres: structure and surface characterization.
Topics: Chitosan; Mannitol; Mass Spectrometry; Microspheres; Nanotechnology; Particle Size | 2007 |
Modulation of ganciclovir intestinal absorption in presence of absorption enhancers.
Topics: Administration, Oral; Animals; Antiviral Agents; beta-Cyclodextrins; Biological Availability; Caco-2 Cells; Chemistry, Pharmaceutical; Chitosan; Dogs; Electric Impedance; Ganciclovir; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Mannitol; Organotechnetium Compounds; Permeability; Rats; Rats, Wistar; Sodium Dodecyl Sulfate; Surface-Active Agents | 2007 |
Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration.
Topics: 3T3 Cells; Alginates; Animals; Apatites; Biocompatible Materials; Biopolymers; Bone Cements; Bone Regeneration; Calcium Phosphates; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Drug Delivery Systems; Hydrogel, Polyethylene Glycol Dimethacrylate; Mannitol; Mice; Models, Biological; Nanostructures; Osteoblasts; Porosity; Tissue Scaffolds | 2008 |
In vitro assessment of acyclovir permeation across cell monolayers in the presence of absorption enhancers.
Topics: Acyclovir; Animals; Antiviral Agents; beta-Cyclodextrins; Biological Transport; Caco-2 Cells; Cell Line; Cell Survival; Chitosan; Dogs; Drug Synergism; Electric Impedance; Excipients; Humans; Kidney; Mannitol; Permeability; Sodium Dodecyl Sulfate | 2008 |
Specific permeability modulation of intestinal paracellular pathway by chitosan-poly(isobutylcyanoacrylate) core-shell nanoparticles.
Topics: Adhesives; Animals; Chitosan; Cyanoacrylates; Diffusion Chambers, Culture; Drug Carriers; Electrochemistry; Enbucrilate; Intestinal Absorption; Male; Mannitol; Molecular Weight; Nanoparticles; Particle Size; Permeability; Rats; Rats, Wistar; Sulfur | 2008 |
Effect of N-betainate and N-piperazine derivatives of chitosan on the paracellular transport of mannitol in Caco-2 cells.
Topics: Betaine; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; Chitosan; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; L-Lactate Dehydrogenase; Mannitol; Piperazines; Solubility; Time Factors | 2008 |
Preparation of honokiol-loaded chitosan microparticles via spray-drying method intended for pulmonary delivery.
Topics: Administration, Inhalation; Administration, Intranasal; Biphenyl Compounds; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Excipients; Lignans; Lung; Mannitol; Nanoparticles; Powders; Respiratory Mucosa; Technology, Pharmaceutical | 2009 |
Chitosan-interferon-β gene complex powder for inhalation treatment of lung metastasis in mice.
Topics: Administration, Inhalation; Animals; Cell Line, Tumor; Chitosan; Electrophoresis, Agar Gel; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Interferon-beta; Luciferases, Firefly; Lung; Lung Neoplasms; Male; Mannitol; Mice; Mice, Inbred Strains; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nucleic Acid Conformation; Plasmids; Powders; Survival Analysis; Time Factors; Treatment Outcome | 2011 |
Microencapsulated chitosan nanoparticles for pulmonary protein delivery: in vivo evaluation of insulin-loaded formulations.
Topics: Animals; Blood Glucose; Chitosan; Drug Carriers; Drug Compounding; Hypoglycemic Agents; Insulin; Lung; Male; Mannitol; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Powders; Rats; Rats, Sprague-Dawley | 2012 |
Lipase entrapment in PVA/Chitosan biodegradable film for reactor coatings.
Topics: Bioreactors; Chitosan; Coated Materials, Biocompatible; Enzymes, Immobilized; Kinetics; Lipase; Mannitol; Microscopy, Electron, Scanning; Polyvinyl Alcohol; Recycling; Solubility; Tensile Strength; Water | 2013 |
Chitosan nanoparticles: preparation, size evolution and stability.
Topics: Animals; Chick Embryo; Chitosan; Chorioallantoic Membrane; Cryoprotective Agents; Drug Compounding; Drug Stability; Insulin; Mannitol; Nanoparticles; Ovalbumin; Particle Size; Polyethylene Glycols; Polyphosphates; Serum Albumin, Bovine; Trehalose | 2013 |
Preparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery.
Topics: Administration, Inhalation; Animals; Bone Density Conservation Agents; Calcitonin; Chitosan; Drug Compounding; Drug Delivery Systems; Lung; Male; Mannitol; Nanoparticles; Particle Size; Powders; Rats; Rats, Sprague-Dawley; Temperature | 2013 |
[Preparation of freeze-dried powder of recombinate hirudin-2 nanoparticle for nasal delivery and permeability through nasal membrane in vitro].
Topics: Absorption; Administration, Intranasal; Animals; Chitosan; Drug Delivery Systems; Drug Stability; Freeze Drying; Glucose; Hirudins; Male; Mannitol; Nanoparticles; Nasal Mucosa; Permeability; Powders; Rabbits; Recombinant Proteins; Technology, Pharmaceutical | 2013 |
Influence of potential inhalation carriers on stability of thymopentin in rat bronchoalveolar lavage fluid.
Topics: Administration, Inhalation; Amino Acids; Animals; Bronchoalveolar Lavage Fluid; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Stability; Half-Life; Lactose; Mannitol; Particle Size; Rats; Rats, Sprague-Dawley; Thymopentin | 2014 |
First in vivo evaluation of particulate nasal dry powder vaccine formulations containing ovalbumin in mice.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antigens; Chemistry, Pharmaceutical; Chitosan; Mannitol; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Powders; Sepharose; Vaccines | 2015 |
Development and Characterization of Gefitinib Loaded Polymeric Nanoparticles by Ionic Gelation Method.
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Chitosan; Cryoprotective Agents; Drug Carriers; Drug Liberation; Gefitinib; Gels; Kinetics; Mannitol; Nanoparticles; Particle Size; Polymers; Polyphosphates; Solubility; Water | 2017 |
Biocompatibility and Targeting Efficiency of Encapsulated Quinapyramine Sulfate-Loaded Chitosan-Mannitol Nanoparticles in a Rabbit Model of Surra.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Chitosan; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; HeLa Cells; Humans; Mannitol; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Quality of Life; Quinolinium Compounds; Rabbits; Trypanosoma | 2018 |
Micro/nanostructured inhalable formulation based on polysaccharides: Effect of a thermoprotectant on powder properties and protein integrity.
Topics: Administration, Inhalation; Chitosan; Drug Carriers; Hyaluronic Acid; Insulin; Mannitol; Nanostructures; Powders | 2018 |
Characterization and Antibiofilm Activity of Mannitol-Chitosan-Blended Paste for Local Antibiotic Delivery System.
Topics: Amikacin; Anti-Bacterial Agents; Biofilms; Chitosan; Drug Carriers; Drug Delivery Systems; Inflammation; Mannitol; Microbial Sensitivity Tests; Polyethylene Glycols; Staphylococcus aureus; Vancomycin | 2019 |
Staphylococcal infection prevention using antibiotic-loaded mannitol-chitosan paste in a rabbit model of implant-associated osteomyelitis.
Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Chitosan; Mannitol; Osteomyelitis; Polyethylene Glycols; Rabbits; Staphylococcal Infections; Titanium; Vancomycin | 2021 |
Dry Powder Inhalers Based on Chitosan-Mannitol Binary Carriers: Effect of the Powder Properties on the Aerosolization Performance.
Topics: Administration, Inhalation; Aerosols; Chitosan; Drug Carriers; Dry Powder Inhalers; Excipients; Mannitol; Particle Size; Powders | 2022 |
Production of high loading insulin nanoparticles suitable for oral delivery by spray drying and freeze drying techniques.
Topics: Chitosan; Cryoprotective Agents; Freeze Drying; Insulin; Mannitol; Nanoparticles; Particle Size; Spray Drying | 2022 |
Dually Responsive Nanoparticles for Drug Delivery Based on Quaternized Chitosan.
Topics: Ammonium Compounds; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Mannitol; Nanoparticles | 2022 |