chitosan has been researched along with guaifenesin in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.28) | 18.2507 |
| 2000's | 5 (8.20) | 29.6817 |
| 2010's | 39 (63.93) | 24.3611 |
| 2020's | 15 (24.59) | 2.80 |
| Authors | Studies |
|---|---|
| Buckton, G; Rillosi, M | 1 |
| Artursson, P; Lennernäs, H; Ocklind, G; Schipper, NG; Stenberg, P; Vârum, KM | 1 |
| Hamman, JH; Kotze, AF; Snyman, D | 1 |
| Junginger, HE; Kotzé, AF; van der Merwe, SM; Verhoef, JC | 1 |
| Bernkop-Schnürch, A; Guggi, D; Krauland, AH | 1 |
| Alonso, MJ; Fabre, M; Prego, C; Torres, D | 1 |
| Lehr, CM; Loftsson, T; Sigurdsson, HH | 1 |
| Di Colo, G; Zambito, Y | 1 |
| du Plessis, LH; Junginger, HE; Kotzé, AF | 1 |
| Hagesaether, E | 1 |
| Chen, C; Huang, Y; Jin, Y; Song, Y; Zhang, Z; Zhou, D; Zhu, X | 1 |
| Casettari, L; Exposito-Harris, R; Fowler, R; Garnett, M; Illum, L; Stolnik, S; Vllasaliu, D | 1 |
| Everaert, A; Hermans, K; Ludwig, A; Van den Plas, D; Weyenberg, W | 1 |
| Badawy, HT; Cannon, CL; Clemons, CB; Ditto, AJ; Kreider, KL; Miller, JK; Milsted, A; Neubig, R; Panzner, MJ; Wilber, JP; Young, GW; Youngs, WJ; Yun, YH | 1 |
| Gonçalves, IC; Martins, MC; Nogueira, F | 1 |
| Ai, X; Ding, W; Han, X; He, Z; Kou, L; Li, L; Lian, H; Liu, X; Ren, G; Sun, J; Sun, Y; Wang, S; Wang, Y; Wu, C; Zhang, T; Zhang, Y | 1 |
| Al Jamal, KT; Alpar, O; Awad, G; El-Shamy, AE; Kan, PL; Mortada, N; Osman, R | 1 |
| Han, XY; Lv, MY; Ma, YF; Qian, LC; Wu, ZP | 1 |
| Ailhas, C; Bejaud, J; Groo, AC; Ivanova, T; Lagarce, F; Mircheva, K; Panaiotov, I; Saulnier, P | 1 |
| Adebisi, AO; Conway, BR | 1 |
| Almeida, R; David, L; Gomes, CP; Gustafsson, JK; Hansson, GC; Pêgo, AP; Pereira, B; Sadio, A | 1 |
| Howard, KA; Li, L; Thomsen, TB | 1 |
| Bernkop-Schnürch, A; Huck, CW; Pearson, JP; Pereira de Sousa, I; Salvenmoser, W; Schmutzler, M; Steiner, C; Veldhuis, GJ; Wilcox, MD | 1 |
| Bernkop-Schnürch, A; Bonengel, S; Perera, G; Salvenmoser, W; Zipser, M | 1 |
| Abdulkarim, M; Agulló, N; Bernkop-Schnürch, A; Borros, SG; Cattoz, B; Griffiths, P; Gumbleton, M | 1 |
| Auberval, N; Bekel, A; Bietiger, W; Diop, M; Frere, Y; Jeandidier, N; Julien David, D; Langlois, A; Marchioni, E; Mura, C; Peronet, C; Pinget, M; Sigrist, S; Vauthier, C; Viciglio, A; Zhao, M | 1 |
| Borrós, S; Oh, S; Pearson, JP; Wilcox, M | 1 |
| Huang, Y; Li, L; Liu, M; Shan, W; Zhang, J; Zhang, Z; Zhong, J; Zhu, X | 1 |
| Bernkop-Schnürch, A; Fichtl, B; Moser, T; Pereira de Sousa, I; Steiner, C | 1 |
| Bajaj, L; Jain, UK; Katare, OP; Madan, J; Pandey, RS; Saini, N; Sodhi, RK | 1 |
| do Amaral Sobral, PJ; López Angulo, DE | 1 |
| Borrós, S; Oh, S | 1 |
| Fang, KM; Huang, TW; Su, HW; Wei, CK | 1 |
| Bernkop-Schnürch, A; Fabiano, A; Zambito, Y | 1 |
| Carvalho-Wodarz, C; Gordon, S; Lehr, CM; Loretz, B; Murgia, X; Schaefer, U; Schwarzkopf, K; Yasar, H | 1 |
| Fan, W; Gan, Y; Guo, S; He, S; Hovgaard, L; Li, X; Xia, D; Yang, M; Zhu, C; Zhu, Q | 1 |
| Cheng, H; Dong, W; Guan, J; Liu, Q; Mao, S; Wang, X; Wu, H; Zhang, M; Zhang, X | 1 |
| Akrivou, M; Bouropoulos, N; Eleftheriadis, GK; Fatouros, DG; Tsibouklis, J; Vizirianakis, IS | 1 |
| Anderski, J; Langer, K; Mahlert, L; Mulac, D | 1 |
| Cheng, H; Dong, W; Kou, Y; Liu, C; Mao, S; Zhang, X | 1 |
| Chen, X; Hu, H; Hu, P; Li, H; Li, P; Shen, Y; Yuan, G; Zou, Y | 1 |
| Hong, Y; Jin, X; Liu, Q; Lu, S; Ping, Q; Rao, Y; Shen, Y; Webster, TJ; Xu, B; Xu, Y | 1 |
| Bernkop-Schnürch, A; Gust, R; Jalil, A; Lupo, N; Nazir, I | 1 |
| Bernkop-Schnürch, A; Le, NN; Le-Vinh, B; Matuszczak, B; Nazir, I | 1 |
| Cavalcanti da Silveira, CO; Costa Franca, TC; Gonçalves, ADS; Silva Filho, EA | 1 |
| Bernkop-Schnürch, A; Jelkmann, M; Laffleur, F; Leichner, C; Prüfert, F | 1 |
| Abd El Hady, WE; El-Sabbagh, HM; Mohamed, EA; Soliman, OAE | 1 |
| Dai, W; Deng, H; He, B; Wang, X; Wu, P; Zhang, H; Zhang, Q; Zhang, Y; Zhao, R; Zhou, S | 1 |
| Albertini, B; Bigi, A; Bonvicini, F; Di Filippo, MF; Dolci, LS; Gentilomi, GA; Orlacchio, R; Panzavolta, S; Passerini, N | 1 |
| Hill, DB; Rouillard, KR; Schoenfisch, MH | 1 |
| Cao, J; Chen, Z; Han, S; Hao, G; Liang, Y; Ma, Q; Qi, H; Sun, Y; Xu, L; Yang, X; Zhang, G | 1 |
| Medina, DI; Ruiz-Pulido, G | 1 |
| Aydemir, S; Baykara, B; Havitcioglu, H; Karakasli, A; Perpelek, M; Tamburaci, S; Tihminlioglu, F | 1 |
| Adoungotchodo, A; Cerruti, M; Guyot, C; Lerouge, S; Taillades, W | 1 |
| Fatima, R; Prasher, P; Sharma, M | 1 |
| Chen, S; Fang, W; Gao, S; Hu, R; Lu, W; Nie, X; Sun, L; Zhang, Q | 1 |
| Cegłowski, M; Filippov, SK; Glassner, M; Hoogenboom, R; Khutoryanskiy, VV; King, S; Lau, WM; Maji, S; Ways, TMM | 1 |
| Li, Y; Liang, Y; Liu, L; Shi, Y; Sun, K; Yin, M; Zhao, Z | 1 |
| Jõemetsa, S; Joyce, P; Prestidge, CA; Wignall, A; Wright, L | 1 |
| Cardoso, VMO; Chorilli, M; Dos Santos Pedriz, I; Ferreira, LMB; Ferreira, NN; Gremião, MPD; Souza, MPC; Zucolotto, V | 1 |
| Al-Gousous, J; García, MA; Hensler, G; Langguth, P; Lennernäs, H; Pielenhofer, J; Wagner, M | 1 |
1 review(s) available for chitosan and guaifenesin
| Article | Year |
|---|---|
An overview of gastrointestinal mucus rheology under different pH conditions and introduction to pH-dependent rheological interactions with PLGA and chitosan nanoparticles.
Topics: Adhesiveness; Administration, Oral; Animals; Chitosan; Drug Carriers; Drug Development; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Mucus; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Rheology; Swine; Viscosity | 2021 |
60 other study(ies) available for chitosan and guaifenesin
| Article | Year |
|---|---|
Modelling mucoadhesion by use of surface energy terms obtained from the Lewis acid-Lewis base approach. II. Studies on anionic, cationic, and unionisable polymers.
Topics: Acid-Base Equilibrium; Acrylic Resins; Adhesiveness; Anions; Cations; Cellulose; Chemical Phenomena; Chemistry, Physical; Chitin; Chitosan; Mathematical Computing; Models, Biological; Mucus; Polyhydroxyethyl Methacrylate; Polymers; Polyvinyls; Surface Properties; Thermodynamics | 1995 |
Chitosans as absorption enhancers of poorly absorbable drugs. 3: Influence of mucus on absorption enhancement.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Biocompatible Materials; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chitin; Chitosan; HT29 Cells; Humans; Ileum; Intestinal Absorption; Intestinal Mucosa; Male; Mucus; Perfusion; Rats; Rats, Sprague-Dawley | 1999 |
Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride.
Topics: Adjuvants, Pharmaceutic; Chemistry, Pharmaceutical; Chitin; Chitosan; Magnetic Resonance Spectroscopy; Molecular Weight; Mucus; Polymers; Surface Tension; Tensile Strength; Time Factors | 2003 |
N-trimethyl chitosan chloride as absorption enhancer in oral peptide drug delivery. Development and characterization of minitablet and granule formulations.
Topics: Adhesives; Administration, Oral; Biological Transport; Capsules; Chitosan; Deamino Arginine Vasopressin; Drug Delivery Systems; Drug Evaluation, Preclinical; Excipients; Humans; Intestinal Absorption; Mucus; Pectins; Peptides; Solubility; Tablets; Technology, Pharmaceutical; Time Factors | 2004 |
Oral insulin delivery: the potential of thiolated chitosan-insulin tablets on non-diabetic rats.
Topics: Adhesives; Administration, Oral; Animals; Blood Glucose; Chitin; Chitosan; Delayed-Action Preparations; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutathione; Imidoesters; Insulin; Insulin Infusion Systems; Intestinal Mucosa; Mucus; Oligopeptides; Rats; Sulfhydryl Compounds; Swine; Tablets; Technology, Pharmaceutical; Trypsin Inhibitor, Bowman-Birk Soybean | 2004 |
Efficacy and mechanism of action of chitosan nanocapsules for oral peptide delivery.
Topics: Administration, Oral; Animals; Caco-2 Cells; Calcitonin; Calcium; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Mucus; Nanostructures; Peptides; Rats; Rats, Sprague-Dawley; Solubility | 2006 |
Assessment of mucoadhesion by a resonant mirror biosensor.
Topics: Acrylic Resins; Adhesiveness; Alginates; Animals; Binding, Competitive; Biosensing Techniques; Carboxymethylcellulose Sodium; Cattle; Chitosan; Glucosamine; Glycoproteins; Hyaluronic Acid; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Molecular Structure; Mucins; Mucus; Polyvinyls; Protein Binding; Serum Albumin, Bovine; Technology, Pharmaceutical | 2006 |
Thiolated quaternary ammonium-chitosan conjugates for enhanced precorneal retention, transcorneal permeation and intraocular absorption of dexamethasone.
Topics: Adhesiveness; Administration, Topical; Animals; Area Under Curve; Chitosan; Cornea; Dexamethasone; Drug Synergism; Excipients; Male; Mucus; Ophthalmic Solutions; Quaternary Ammonium Compounds; Rabbits; Time Factors | 2010 |
Nasal and rectal delivery of insulin with chitosan and N-trimethyl chitosan chloride.
Topics: Absorption; Administration, Intranasal; Administration, Rectal; Amination; Animals; Blood Glucose; Chitosan; Drug Carriers; Hydrogen-Ion Concentration; Insulin; Intestinal Mucosa; Intestinal Secretions; Male; Mucus; Nasal Mucosa; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Rectum; Solubility | 2010 |
Permeation modulating properties of natural polymers--effect of molecular weight and mucus.
Topics: Chitosan; Excipients; Fluoresceins; Fluorescent Dyes; Goblet Cells; HT29 Cells; Humans; Hyaluronic Acid; Methotrexate; Molecular Weight; Mucus; Pectins; Permeability; Polymers | 2011 |
Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport.
Topics: Administration, Oral; Amino Acid Sequence; Animals; Blood Glucose; Caco-2 Cells; Cell Death; Chitosan; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Goblet Cells; Humans; Hypoglycemic Agents; Ileum; In Vitro Techniques; Insulin; Intestinal Absorption; Male; Molecular Sequence Data; Mucus; Nanoparticles; Peptides; Protein Transport; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2012 |
Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study.
Topics: Adhesiveness; Caco-2 Cells; Cell Survival; Chitosan; Dose-Response Relationship, Drug; Electric Impedance; Excipients; Humans; Intestinal Absorption; Intestinal Mucosa; Mucus; Permeability; Respiratory Mucosa; Tight Junctions; Time Factors | 2012 |
Full factorial design, physicochemical characterisation and biological assessment of cyclosporine A loaded cationic nanoparticles.
Topics: Animals; Cations; Chitosan; Cyclosporine; Drug Carriers; Drug Compounding; Emulsions; Epithelial Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Lactic Acid; Mucus; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Static Electricity; Swine; Tears | 2012 |
Nanoparticle deposition onto biofilms.
Topics: Biofilms; Chitosan; Diffusion; Drug Delivery Systems; Lung; Models, Theoretical; Mucus; Nanoparticles; Organophosphates; Polyethylene Glycols; Polymers; Pseudomonas aeruginosa | 2013 |
Effect of gastric environment on Helicobacter pylori adhesion to a mucoadhesive polymer.
Topics: Adhesiveness; Bacterial Adhesion; Buffers; Chitosan; Helicobacter pylori; Hydrogen-Ion Concentration; Microbial Viability; Mucus; Pepsin A; Spectroscopy, Fourier Transform Infrared; Stomach; Urea | 2013 |
Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism.
Topics: Acetylcysteine; Animals; Chitosan; Drug Carriers; Micelles; Mucus; Paclitaxel; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Thermogravimetry; Vitamin E | 2013 |
Inhalable DNase I microparticles engineered with biologically active excipients.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Inhalation; Aerosols; Animals; Chitosan; Cystic Fibrosis; Delayed-Action Preparations; Deoxyribonuclease I; Dextrans; Drug Carriers; Drug Delivery Systems; Epithelial Cells; Excipients; Lactic Acid; Macrophages; Mice; Mucus; Ovalbumin; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Viscosity | 2013 |
Chitosan-zinc chelate improves intestinal structure and mucosal function and decreases apoptosis in ileal mucosal epithelial cells in weaned pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Biological Availability; Chelating Agents; Chitosan; Diet; Dietary Supplements; Endotoxins; Epithelial Cells; Ileum; Immunoglobulin A, Secretory; In Situ Nick-End Labeling; Intestinal Mucosa; Intestine, Small; Lactic Acid; Male; Mucus; Swine; Weaning; Zinc | 2014 |
Development of 2D and 3D mucus models and their interactions with mucus-penetrating paclitaxel-loaded lipid nanocapsules.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Diffusion; Drug Carriers; Models, Biological; Mucus; Nanocapsules; Paclitaxel; Particle Size; Polyethylene Glycols; Surface Properties; Swine | 2014 |
Lectin-conjugated microspheres for eradication of Helicobacter pylori infection and interaction with mucus.
Topics: Adhesiveness; Animals; Anti-Bacterial Agents; Cellulose; Chitosan; Clarithromycin; Concanavalin A; Diffusion; Drug Stability; Gastric Juice; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Membranes, Artificial; Microspheres; Mucins; Mucus; Powder Diffraction; Spectroscopy, Fourier Transform Infrared; Swine; X-Ray Diffraction | 2014 |
Modified-chitosan/siRNA nanoparticles downregulate cellular CDX2 expression and cross the gastric mucus barrier.
Topics: Animals; CDX2 Transcription Factor; Cell Line, Tumor; Chitosan; Colon; Down-Regulation; Gastric Mucosa; Homeodomain Proteins; Humans; Imidazoles; Mice; Mucus; Nanoparticles; RNA, Small Interfering; Transfection | 2014 |
Mucus barrier-triggered disassembly of siRNA nanocarriers.
Topics: Animals; Chitosan; Diffusion; Fluorescent Dyes; Glycoproteins; Hydrodynamics; Intestinal Mucosa; Kinetics; Microfluidics; Mucins; Mucus; Nanomedicine; Nanoparticles; Nucleic Acids; Particle Size; RNA Interference; RNA, Small Interfering; Swine | 2014 |
Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles.
Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Chondroitin Sulfates; Diffusion; Drug Carriers; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Mucus; Nanoparticles; Particle Size; Polymers; Swine | 2015 |
Development of phosphorylated nanoparticles as zeta potential inverting systems.
Topics: Alkaline Phosphatase; Caco-2 Cells; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Humans; Intestinal Mucosa; Mucus; Nanoparticles; Particle Size; Phosphates; Phosphorylation; Phosphotyrosine; Polymers | 2015 |
Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles.
Topics: Acrylic Resins; Animals; Biological Transport; Chitosan; Diffusion; Electrolytes; Jejunum; Lactic Acid; Microscopy, Atomic Force; Mucus; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rheology; Surface Properties; Swine; Virion | 2015 |
Design, characterisation, and bioefficiency of insulin-chitosan nanoparticles after stabilisation by freeze-drying or cross-linking.
Topics: Animals; Blood Glucose; Caco-2 Cells; Chemistry, Pharmaceutical; Chitosan; Cross-Linking Reagents; Drug Delivery Systems; Drug Design; Drug Stability; Excipients; Freeze Drying; Humans; Insulin; Male; Mucus; Nanoparticles; Rats; Rats, Wistar | 2015 |
Optimal design for studying mucoadhesive polymers interaction with gastric mucin using a quartz crystal microbalance with dissipation (QCM-D): Comparison of two different mucin origins.
Topics: Abattoirs; Adhesiveness; Adsorption; Animals; Chemical Phenomena; Chitosan; Elastic Modulus; Gastric Mucosa; Hyaluronic Acid; Hydrogen-Ion Concentration; Kinetics; Mucus; Polyamines; Quartz Crystal Microbalance Techniques; Shear Strength; Sulfhydryl Compounds; Sus scrofa; Viscosity | 2015 |
Efficient mucus permeation and tight junction opening by dissociable "mucus-inert" agent coated trimethyl chitosan nanoparticles for oral insulin delivery.
Topics: Acrylamides; Administration, Oral; Animals; Blood Glucose; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Drug Liberation; Epithelial Cells; Female; Humans; Hypoglycemic Agents; Insulin; Male; Mucus; Nanoparticles; Permeability; Rats, Sprague-Dawley; Tight Junctions | 2016 |
Insulin loaded mucus permeating nanoparticles: Addressing the surface characteristics as feature to improve mucus permeation.
Topics: Animals; Chitosan; Chondroitin Sulfates; Drug Delivery Systems; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Insulin; Intestinal Mucosa; Mucus; Nanoparticles; Permeability; Polyethylene Glycols; Surface Properties; Swine | 2016 |
Intravaginal administration of metformin hydrochloride loaded cationic niosomes amalgamated with thermosensitive gel for the treatment of polycystic ovary syndrome: In vitro and in vivo studies.
Topics: Adhesiveness; Administration, Intravaginal; Animals; Cations; Chitosan; Drug Liberation; Female; Gels; Glycerophosphates; Hormones; Liposomes; Metformin; Mucus; Particle Size; Polycystic Ovary Syndrome; Rats, Wistar; Static Electricity; Sus scrofa; Temperature; Viscosity | 2016 |
Characterization of gelatin/chitosan scaffold blended with aloe vera and snail mucus for biomedical purpose.
Topics: Aloe; Amino Acids; Animals; Chitosan; Freeze Drying; Gelatin; Microscopy, Electron, Scanning; Mucus; Snails; Spectroscopy, Fourier Transform Infrared; Sus scrofa; Tissue Scaffolds; X-Ray Diffraction | 2016 |
Mucoadhesion vs mucus permeability of thiolated chitosan polymers and their resulting nanoparticles using a quartz crystal microbalance with dissipation (QCM-D).
Topics: Adhesiveness; Adsorption; Animals; Chitosan; Gastric Mucins; Mucus; Nanoparticles; Particle Size; Permeability; Polymers; Quartz Crystal Microbalance Techniques; Sulfhydryl Compounds; Surface Properties; Swine | 2016 |
Chitosan promotes aquaporin formation and inhibits mucociliary differentiation of nasal epithelial cells through increased TGF-β1 production.
Topics: Aquaporins; Cell Differentiation; Cell Proliferation; Cell Shape; Cells, Cultured; Chitosan; Cilia; Epithelial Cells; Humans; Mucus; Nose; Smad Proteins; Tight Junctions; Transforming Growth Factor beta1; Wound Healing | 2017 |
About the impact of water movement on the permeation behaviour of nanoparticles in mucus.
Topics: Animals; Chitosan; Diffusion; Hyaluronic Acid; Mucus; Nanoparticles; Particle Size; Rheology; Sodium Chloride; Swine; Viscosity | 2017 |
Modelling the bronchial barrier in pulmonary drug delivery: A human bronchial epithelial cell line supplemented with human tracheal mucus.
Topics: Aerosols; Bronchi; Cell Culture Techniques; Cell Line; Cell Membrane Permeability; Chitosan; Coated Materials, Biocompatible; Drug Carriers; Electric Impedance; Epithelial Cells; Female; Fluorescein; Freeze Drying; Humans; Male; Middle Aged; Mucus; Nanoparticles; Permeability; Respiratory Mucosa | 2017 |
Functional nanoparticles exploit the bile acid pathway to overcome multiple barriers of the intestinal epithelium for oral insulin delivery.
Topics: Administration, Oral; Animals; Bile Acids and Salts; Biological Availability; Caco-2 Cells; Cardiovascular System; Carrier Proteins; Chitosan; Deoxycholic Acid; Diabetes Mellitus, Experimental; Drug Carriers; Drug Liberation; Drug Trafficking; Humans; Insulin; Intestinal Mucosa; Male; Membrane Glycoproteins; Mucus; Nanoparticles; Organic Anion Transporters, Sodium-Dependent; Particle Size; Permeability; Rats, Sprague-Dawley; Surface Properties; Symporters | 2018 |
Design and intestinal mucus penetration mechanism of core-shell nanocomplex.
Topics: Alginates; Animals; Chitosan; Insulin; Intestinal Absorption; Intestinal Mucosa; Male; Mucus; Nanoparticles; Rats, Wistar; Swine | 2018 |
Polymer-Lipid Microparticles for Pulmonary Delivery.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Inhalation; Budesonide; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Compounding; Drug Liberation; Excipients; Female; Humans; Lactose; Leucine; Male; Mucus; Particle Size; Polyvinyl Alcohol; Pulmonary Surfactants | 2018 |
Mucus-penetrating nanoparticles: Promising drug delivery systems for the photodynamic therapy of intestinal cancer.
Topics: Administration, Oral; Caco-2 Cells; Chitosan; Drug Delivery Systems; Humans; Intestinal Mucosa; Intestinal Neoplasms; Lactic Acid; Mucus; Nanoparticles; Permeability; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porphyrins | 2018 |
Enhanced oral insulin delivery via surface hydrophilic modification of chitosan copolymer based self-assembly polyelectrolyte nanocomplex.
Topics: Administration, Oral; Animals; Chitosan; Drug Carriers; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Hypoglycemic Agents; Insulin; Male; Mucus; Nanoparticles; Polyelectrolytes; Polyethylene Glycols; Polymers; Rats; Rats, Wistar; Surface Properties | 2019 |
Mucus penetration enhanced lipid polymer nanoparticles improve the eradication rate of Helicobacter pylori biofilm.
Topics: Anti-Bacterial Agents; Biofilms; Biopolymers; Cell Adhesion; Cell Line, Tumor; Chitosan; Clarithromycin; Glycolipids; Helicobacter pylori; Humans; Mucus; Nanoparticles; Polyethylene Glycols | 2019 |
Preparation, intestinal segment stability, and mucoadhesion properties of novel thymopentin-loaded chitosan derivatives coated with poly (n-butyl) cyanoacrylate nanoparticles.
Topics: Adhesiveness; Animals; Biocompatible Materials; Chitosan; Drug Carriers; Drug Liberation; Enbucrilate; Intestines; Mucus; Nanoparticles; Particle Size; Rats, Sprague-Dawley; Static Electricity; Thymopentin; Time Factors | 2019 |
In vitro evaluation of intravesical mucoadhesive self-emulsifying drug delivery systems.
Topics: Adhesiveness; Administration, Intravesical; Animals; Cell Survival; Chitosan; Drug Delivery Systems; Emulsions; Mucous Membrane; Mucus; Niacinamide; Sodium Dodecyl Sulfate; Swine; Urinary Bladder | 2019 |
Chitosan based micelle with zeta potential changing property for effective mucosal drug delivery.
Topics: Adhesiveness; Caco-2 Cells; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; HEK293 Cells; Humans; Micelles; Mucus; Permeability; Phosphates; Stearic Acids | 2019 |
Computational studies of mucin 2 and its interactions with thiolated chitosans: a new insight for mucus adhesion and drug retention.
Topics: Chitosan; Mucin-2; Mucus; Pharmaceutical Preparations; Sulfhydryl Compounds | 2020 |
Intestinal enzyme delivery: Chitosan/tripolyphosphate nanoparticles providing a targeted release behind the mucus gel barrier.
Topics: Animals; beta-Galactosidase; Caco-2 Cells; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Gels; Humans; Intestinal Mucosa; Intestines; Mucus; Nanoparticles; Particle Size; Swine | 2019 |
In vitro-in vivo evaluation of chitosan-PLGA nanoparticles for potentiated gastric retention and anti-ulcer activity of diosmin.
Topics: Adhesiveness; Animals; Anti-Ulcer Agents; Calorimetry, Differential Scanning; Chitosan; Diosmin; Drug Carriers; Drug Liberation; Duodenum; Gastric Mucosa; Kinetics; Male; Mucus; Nanoparticles; NF-kappa B; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Stomach; Ulcer; X-Ray Diffraction | 2019 |
Thiolated Nanoparticles Overcome the Mucus Barrier and Epithelial Barrier for Oral Delivery of Insulin.
Topics: Acrylic Resins; Administration, Oral; Animals; Biological Availability; Cell Line, Tumor; Chitosan; Cysteine; Diabetes Mellitus, Experimental; Drug Carriers; Epithelial Cells; Humans; Insulin; Microscopy, Electron, Transmission; Mucus; Nanoparticles; Nicotinic Acids; Picolinic Acids; Rats; Sulfhydryl Compounds; Tight Junctions | 2020 |
Functional properties of chitosan films modified by snail mucus extract.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Chemical Phenomena; Chitosan; Mucus; Snails; Spectrum Analysis; Steam; Thermogravimetry | 2020 |
Antibiofilm and mucolytic action of nitric oxide delivered via gas or macromolecular donor using in vitro and ex vivo models.
Topics: Administration, Inhalation; Animals; Biofilms; Chitosan; Cystic Fibrosis; Humans; In Vitro Techniques; Mucus; Nitric Oxide; Pseudomonas aeruginosa; Sputum; Swine | 2020 |
Overcoming Multiple Absorption Barrier for Insulin Oral Delivery Using Multifunctional Nanoparticles Based on Chitosan Derivatives and Hyaluronic Acid.
Topics: Administration, Oral; Animals; Biological Transport; Caco-2 Cells; Cell Death; Chitosan; Diabetes Mellitus, Experimental; Electric Impedance; Endocytosis; Guanidines; Humans; Hyaluronic Acid; Hypoglycemic Agents; Insulin; Intestinal Absorption; Male; Mucus; Multifunctional Nanoparticles; Nanoparticles; Rats; Solubility; Swine | 2020 |
Bioactive snail mucus-slime extract loaded chitosan scaffolds for hard tissue regeneration: the effect of mucoadhesive and antibacterial extracts on physical characteristics and bioactivity of chitosan matrix.
Topics: Animals; Anti-Bacterial Agents; Biological Products; Cell Line; Cell Proliferation; Cell Survival; Chitosan; Chondrogenesis; Helix, Snails; Mucus; Osteogenesis; Regeneration; Tissue Engineering; Tissue Scaffolds | 2021 |
A catechol-chitosan-based adhesive and injectable hydrogel resistant to oxidation and compatible with cell therapy.
Topics: Adhesives; Animals; Biocompatible Materials; Catechols; Cell Line; Cell Survival; Cell- and Tissue-Based Therapy; Chitosan; Fibroblasts; Hydrogels; Mice; Mucus; Oxidation-Reduction | 2021 |
Cationic polysaccharides: emerging drug delivery vehicle across the physiological mucus barrier.
Topics: Cations; Chitosan; Drug Carriers; Drug Delivery Systems; Mucus; Polysaccharides | 2022 |
Mucus-Penetrating Alginate-Chitosan Nanoparticles Loaded with Berberine Hydrochloride for Oral Delivery to the Inflammation Site of Ulcerative Colitis.
Topics: Administration, Oral; Alginates; Berberine; Chitosan; Colitis, Ulcerative; Drug Carriers; Drug Delivery Systems; Humans; Inflammation; Mucus; Nanoparticles | 2022 |
Mucus-penetrating nanoparticles based on chitosan grafted with various non-ionic polymers: Synthesis, structural characterisation and diffusion studies.
Topics: Animals; Cattle; Chitosan; Humans; Mucus; Nanoparticles; Polymers; Pyrrolidinones; Sheep | 2022 |
Mucus- and pH-mediated controlled release of core-shell chitosan nanoparticles in the gastrointestinal tract for diabetes treatment.
Topics: Administration, Oral; Animals; Chitosan; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Drug Carriers; Gastrointestinal Tract; Hydrogen-Ion Concentration; Insulin; Mucus; Nanoparticles | 2023 |
A membrane-free microfluidic approach to mucus permeation for efficient differentiation of mucoadhesive and mucopermeating nanoparticulate systems.
Topics: Chitosan; Drug Carriers; Drug Delivery Systems; Intestinal Mucosa; Microfluidics; Mucus; Nanoparticles | 2023 |
Understanding mucus modulation behavior of chitosan oligomers and dextran sulfate combining light scattering and calorimetric observations.
Topics: Biopolymers; Chitosan; Dextran Sulfate; Mucins; Mucus | 2023 |
Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus.
Topics: Acyclovir; Chitosan; Excipients; Food-Drug Interactions; Humans; Intestinal Absorption; Mucus | 2023 |