Page last updated: 2024-08-25

chitosan and eye

chitosan has been researched along with eye in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (18.64)29.6817
2010's39 (66.10)24.3611
2020's9 (15.25)2.80

Authors

AuthorsStudies
Alonso, MJ; De Campos, AM; Sánchez, A1
Baeyens, V; Buri, P; Felt, O; Gurny, R1
Alonso, MJ; Sánchez, A1
Burgalassi, S; Di Colo, G; Nardini, I; Saettone, MF; Zambito, Y1
Barbu, E; Green, KL; Nastasescu, O; Sarvaiya, I; Tsibouklis, J; Verestiuc, L1
Alonso, MJ; Calonge, M; Carvalho, EL; Diebold, Y; Jarrín, M; Orea, M; Sáez, V; Seijo, B1
Ahmad, FJ; Chopra, S; Khar, RK; Kohli, K; Motwani, SK; Talegaonkar, S1
Bhutto, I; Grebe, R; Kim, SY; Leong, K; Lutty, GA; McLeod, DS; Mennon, M; Merges, C; Prow, TW; Rodriguez, L; Uno, K1
Duan, Y; Ge, J; Guan, X; Quan, D; Shao, T; Ye, H; Zhuo, Y1
Alonso, MJ; de la Fuente, M; Paolicelli, P; Sánchez, A; Seijo, B1
Barbu, E; Iancu, M; Jatariu, A; Lungu, A; Tsibouklis, J; Verestiuc, L1
Abdelbary, G1
Addo, RT; Akande, J; D'Souza, MJ; Patel, NJ; Siddig, A; Siwale, R; Uddin, AN1
Lin, HR; Lin, YJ; Wang, TS; Yu, SP1
Dangl, D; Hoffer, M; Hornof, M; Kuntner, C; Kvaternik, H; Langer, O; Wanek, T1
Refai, H; Tag, R1
Ahmad, FJ; Akhter, S; Jain, GK; Jayabalan, N; Khar, RK; Pathan, SA; Talegaonkar, S1
Calonge, M; Contreras-Ruiz, L; de la Fuente, M; Diebold, Y; Fernández, I; López-García, A; Párraga, JE; Sánchez, A; Seijo, B1
Kant, S; Maiti, P; Nagarwal, RC; Pandit, JK; Singh, PN1
Alany, RG; Green, CR; Rupenthal, ID1
Shinde, UA; Singh, KH1
Li, N; Pan, WS; Sui, CG; Wang, M; Zhuang, CY1
Cunha-Júnior, Ada S; Faraco, AG; Fulgêncio, Gde O; Ribeiro, RR; Viana, FA; Yoshida, MI1
Agrawal, AK; Das, M; Jain, S1
Costin, D; Gardikiotis, F; Peptu, C; Popa, M1
Chaiyasan, W; Srinivas, SP; Tiyaboonchai, W1
Arunkumar, R; Baskaran, V; Harish Prashanth, KV1
Carmichael, T; Choonara, YE; Du Toit, LC; Govender, T; Kumar, P; Pillay, V1
Başaran, E; Berkman, MS; Büyükköroğlu, G; Yazan, Y; Yenilmez, E1
Nair, HA; Shete, JN; Shinde, UA; Singh, KH1
Fang, IM; Yang, CH; Yang, CM1
Chiseliţă, D; Costin, D; Costuleanu, M; Moraru, AD; Peptu, C; Popa, M; Sava, A1
Bhatta, RS; Chandasana, H; Chhonker, YS; Mitra, K; Prasad, YD; Shukla, PK; Vishvkarma, A1
Addo, E; Addo, RT; Akande, J; D'Souza, MJ; Jones, A; Nettey, H; Patel, NJ; Siddig, A; Siwale, RC; Ubale, RV; Yeboah, KG1
Bikiaris, DN; Karavas, E; Kostoglou, M; Koukaras, EN; Koutris, E; Siafaka, PI; Titopoulou, A1
Kamel, R; Mahmoud, AA; Salama, AH1
da Silva, SB; Ferreira, D; Pintado, M; Sarmento, B1
Adelli, GR; Balguri, SP; Majumdar, S1
Ghorab, D; Morsi, N; Refai, H; Teba, H1
Chen, H; Deng, F; Hu, W; Tang, Y; Zhang, L1
Agrawal, R; Geifman Shochat, S; Larsson, A; Moreno, M; Nirmal, J; Nirmal, S; Pow, PY; Quah, ST; Radhakrishnan, K; Tabitha, TST; Venkatraman, S1
Cheng, B; Li, J; Liu, D; Pan, H; Wu, Q1
Ali, A; Bukhari, SNA; Imam, SS1
Abdalla, AM; Alqurshi, A; Gabr, KE; Guda, TK; Hanafy, AF; Royall, PG1
Abe, T; Daigaku, R; Hoshi, A; Kaji, H; Nagai, N; Nakazawa, T; Nezhad, ZK; Nishizawa, M; Saijo, S; Song, Y; Terata, K1
Detsi, A; Pontillo, ARN1
Lei, L; Li, X; Song, Z; Xiong, T; Yu, J; Yu, X1
Monpara, JD; Pai, RV; Vavia, PR1
Cardoso, VN; Castilho, RO; Cronemberger, S; Faraco, AAG; Fernandes, SOA; Ferreira, AJ; Foureaux, G; Franca, JR; Fuscaldi, LL; Nogueira, JC; Ribeiro, TG; Yoshida, MI1
Bao, Z; Lei, L; Li, X; Lin, D; Liu, H; Shi, H; Wang, Y; Xu, X; Yu, A1
Cao, F; Cheng, Y; Sun, L; Xu, X; Zhou, L1
Bao, Z; Dai, M; Li, X; Lin, D; Liu, H; Shi, H; Wang, Y; Xu, X; Yu, A1
Almeida, AJ; Braz, BS; Delgado, E; Gonçalves, L; Marto, J; Silva, B1
Pai, RV; Vavia, PR1
Alshehri, S; Bin-Jumah, M; Gilani, SJ; Imam, SS; Jahangir, MA; Kala, C; Taleuzzaman, M; Yasir, M; Zafar, A1
Ghosh, G; Kar, B; Naik, PK; Pradhan, D; Rath, G; Sahu, DK1
Bao, Z; Dai, M; Hu, Y; Jin, B; Lei, L; Li, X; Lin, D; Shi, H; Wang, Y; Yu, A1
Chen, K; Gu, D; Pan, H; Pan, W; Sun, H; Tan, G; Wang, L1
Liu, J; Peng, Q; Tang, X; Yan, R1

Reviews

5 review(s) available for chitosan and eye

ArticleYear
The potential of chitosan in ocular drug delivery.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:11

    Topics: Administration, Topical; Biocompatible Materials; Chitin; Chitosan; Cyclosporine; Drug Delivery Systems; Eye; Humans

2003
Chitosan nanoparticles for drug delivery to the eye.
    Expert opinion on drug delivery, 2009, Volume: 6, Issue:3

    Topics: Administration, Topical; Animals; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Eye; Eye Diseases; Gene Transfer Techniques; Humans; Nanoparticles; Ophthalmic Solutions

2009
In situ gel systems as 'smart' carriers for sustained ocular drug delivery.
    Expert opinion on drug delivery, 2012, Volume: 9, Issue:4

    Topics: Absorption; Adhesiveness; Administration, Ophthalmic; Biocompatible Materials; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Excipients; Eye; Gels; Glucans; Humans; Ophthalmic Solutions; Poloxamer; Polymers; Xylans

2012
Nanoparticles for ocular drug delivery: modified and non-modified chitosan as a promising biocompatible carrier.
    Nanomedicine (London, England), 2019, Volume: 14, Issue:14

    Topics: Administration, Ophthalmic; Animals; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Eye; Eye Diseases; Humans; Nanoparticles; Nanotechnology; Pharmaceutical Preparations; Polylactic Acid-Polyglycolic Acid Copolymer

2019
Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: A review.
    International journal of biological macromolecules, 2023, Jul-01, Volume: 242, Issue:Pt 3

    Topics: Chitosan; Drug Delivery Systems; Eye; Eye Diseases; Humans; Hyaluronic Acid; Polymers

2023

Trials

1 trial(s) available for chitosan and eye

ArticleYear
A Novel Method for Preparing Surface-Modified Fluocinolone Acetonide Loaded PLGA Nanoparticles for Ocular Use: In Vitro and In Vivo Evaluations.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:5

    Topics: Administration, Ophthalmic; Animals; Chitosan; Cross-Over Studies; Delayed-Action Preparations; Drug Carriers; Eye; Fluocinolone Acetonide; Lactic Acid; Male; Nanoparticles; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits

2016

Other Studies

53 other study(ies) available for chitosan and eye

ArticleYear
Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A.
    International journal of pharmaceutics, 2001, Aug-14, Volume: 224, Issue:1-2

    Topics: Administration, Topical; Animals; Antifungal Agents; Chitin; Chitosan; Conjunctiva; Cornea; Cyclosporine; Drug Carriers; Drug Delivery Systems; Eye; Male; Microscopy, Electron; Mucous Membrane; Ophthalmic Solutions; Particle Size; Rabbits

2001
Delivery of antibiotics to the eye using a positively charged polysaccharide as vehicle.
    AAPS pharmSci, 2001, Volume: 3, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Biological Availability; Biopolymers; Chitin; Chitosan; Dosage Forms; Drug Delivery Systems; Eye; Male; Molecular Structure; Molecular Weight; Ofloxacin; Rabbits; Solubility; Solutions; Tears; Time Factors; Tobramycin; Treatment Outcome

2001
Effect of chitosan and of N-carboxymethylchitosan on intraocular penetration of topically applied ofloxacin.
    International journal of pharmaceutics, 2004, Apr-01, Volume: 273, Issue:1-2

    Topics: Animals; Anti-Infective Agents; Aqueous Humor; Biological Availability; Chitin; Chitosan; Eye; Instillation, Drug; Male; Ofloxacin; Ophthalmic Solutions; Permeability; Rabbits; Tears

2004
Functionalized chitosan/NIPAM (HEMA) hybrid polymer networks as inserts for ocular drug delivery: synthesis, in vitro assessment, and in vivo evaluation.
    Journal of biomedical materials research. Part A, 2006, Jun-15, Volume: 77, Issue:4

    Topics: Acrylamides; Animals; Anti-Bacterial Agents; Biocompatible Materials; Chitosan; Cholinergic Antagonists; Drug Delivery Systems; Eye; Male; Methacrylates; Rabbits

2006
Ocular drug delivery by liposome-chitosan nanoparticle complexes (LCS-NP).
    Biomaterials, 2007, Volume: 28, Issue:8

    Topics: Biocompatible Materials; Cell Line, Transformed; Chitosan; Drug Delivery Systems; Eye; Humans; Liposomes; Nanoparticles

2007
Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: formulation, optimisation and in vitro characterisation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 68, Issue:3

    Topics: Administration, Topical; Alginates; Chemistry, Pharmaceutical; Chitosan; Eye; Fluoroquinolones; Gatifloxacin; Glucuronic Acid; Hexuronic Acids; Microscopy, Electron, Transmission; Nanoparticles; Pharmaceutical Vehicles; Solubility

2008
Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium.
    Nanomedicine : nanotechnology, biology, and medicine, 2008, Volume: 4, Issue:4

    Topics: Animals; Chitosan; Eye; Green Fluorescent Proteins; Immunohistochemistry; Microscopy, Confocal; Microscopy, Electron, Transmission; Microscopy, Immunoelectron; Nanoparticles; Polymers; Rabbits; Retina; Retinal Pigment Epithelium; Transfection

2008
Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon's capsule fibroblasts in vitro.
    Molecular vision, 2008, Volume: 14

    Topics: Analysis of Variance; Cell Proliferation; Cells, Cultured; Chitosan; Connective Tissue Cells; Down-Regulation; Eye; Fibroblasts; HeLa Cells; Humans; I-kappa B Kinase; NF-kappa B; Nuclear Magnetic Resonance, Biomolecular; Particle Size; Polyethylene Glycols; Polyethyleneimine; Polymers; RNA Interference; RNA, Small Interfering; Transfection

2008
Hybrid polymeric hydrogels for ocular drug delivery: nanoparticulate systems from copolymers of acrylic acid-functionalized chitosan and N-isopropylacrylamide or 2-hydroxyethyl methacrylate.
    Nanotechnology, 2009, Jun-03, Volume: 20, Issue:22

    Topics: Acrylamides; Anti-Bacterial Agents; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Drug Stability; Eye; Humans; Hydrogels; Kinetics; Methacrylates; Models, Theoretical; Muramidase; Nanoparticles; Particle Size; Temperature

2009
Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes.
    Pharmaceutical development and technology, 2011, Volume: 16, Issue:1

    Topics: Adhesiveness; Animals; Anti-Bacterial Agents; Chitosan; Ciprofloxacin; Drug Carriers; Drug Compounding; Eye; Liposomes; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Mucous Membrane; Ophthalmic Solutions; Particle Size; Rabbits; Solubility; Staphylococcus aureus; Static Electricity; Surface Properties; Toxicity Tests, Acute

2011
Formulation, characterization and testing of tetracaine hydrochloride-loaded albumin-chitosan microparticles for ocular drug delivery.
    Journal of microencapsulation, 2010, Volume: 27, Issue:2

    Topics: Anesthetics, Local; Animals; Cattle; Cell Line; Cell Survival; Chitosan; Cornea; Drug Carriers; Drug Compounding; Drug Stability; Epithelial Cells; Eye; Humans; Ophthalmic Solutions; Particle Size; Rabbits; Serum Albumin, Bovine; Tetracaine

2010
High pH tolerance of a chitosan-PAA nanosuspension for ophthalmic delivery of pilocarpine.
    Journal of biomaterials science. Polymer edition, 2010, Volume: 21, Issue:2

    Topics: Acrylic Resins; Animals; Chitosan; Drug Carriers; Eye; Female; Hydrogen Peroxide; Hydrogen-Ion Concentration; Male; Molecular Weight; Nanostructures; Particle Size; Pilocarpine; Rabbits; Solubility; Suspensions; Temperature

2010
Radiosynthesis and assessment of ocular pharmacokinetics of (124)I-labeled chitosan in rabbits using small-animal PET.
    Molecular imaging and biology, 2011, Volume: 13, Issue:2

    Topics: Animals; Area Under Curve; Chitosan; Eye; Female; Iodine Radioisotopes; Isotope Labeling; Positron-Emission Tomography; Rabbits; Time Factors

2011
Development and characterization of sponge-like acyclovir ocular minitablets.
    Drug delivery, 2011, Volume: 18, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Chemistry, Pharmaceutical; Chitosan; Columbidae; Delayed-Action Preparations; Eye; Freeze Drying; Gels; Keratitis, Herpetic; Particle Size; Polymers; Rabbits; Simplexvirus; Tablets; Viscosity; Vision, Ocular

2011
Microscopic and spectroscopic evaluation of novel PLGA-chitosan Nanoplexes as an ocular delivery system.
    Colloids and surfaces. B, Biointerfaces, 2011, Feb-01, Volume: 82, Issue:2

    Topics: Animals; Chitosan; Drug Delivery Systems; Eye; Fluorescent Dyes; Humans; Lactic Acid; Materials Testing; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Rhodamines; Spectrophotometry; Time Factors

2011
Intracellular trafficking of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured human ocular surface cells.
    Molecular vision, 2011, Jan-27, Volume: 17

    Topics: Alkaline Phosphatase; Animals; Caveolin 1; Cell Survival; Cells, Cultured; Chitosan; Endocytosis; Eye; Humans; Hyaluronan Receptors; Hyaluronic Acid; Lysosomes; Mice; Nanoparticles; Plasmids; Temperature

2011
Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: characterization, in-vitro and in-vivo study.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:2

    Topics: Animals; Chitosan; Drug Delivery Systems; Eye; Female; Fluorouracil; Male; Nanoparticles; Particle Size; Rabbits; X-Ray Diffraction

2011
Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: physicochemical characterisation and in vitro release.
    International journal of pharmaceutics, 2011, Jun-15, Volume: 411, Issue:1-2

    Topics: Administration, Ophthalmic; Alginates; Biological Availability; Carrageenan; Chemical Phenomena; Chitosan; Cornea; Drug Delivery Systems; Excipients; Eye; Gels; Glucuronic Acid; Hexuronic Acids; Humans; Ophthalmic Solutions; Polymers; Polysaccharides; Polysaccharides, Bacterial; Rheology; Solubility; Tears; Viscosity

2011
Chitosan nanoparticles for controlled delivery of brimonidine tartrate to the ocular membrane.
    Die Pharmazie, 2011, Volume: 66, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Calorimetry, Differential Scanning; Chitosan; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Electrochemistry; Excipients; Eye; Freeze Drying; Intraocular Pressure; Irritants; Membranes; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Ophthalmic Solutions; Particle Size; Quinoxalines; Rabbits; Solubility; Spectroscopy, Fourier Transform Infrared

2011
Low molecular weight chitosan-coated liposomes for ocular drug delivery: in vitro and in vivo studies.
    Drug delivery, 2012, Volume: 19, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Chitosan; Conjunctiva; Drug Delivery Systems; Eye; Liposomes; Male; Models, Biological; Molecular Weight; Rabbits

2012
New mucoadhesive chitosan film for ophthalmic drug delivery of timolol maleate: in vivo evaluation.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2012, Volume: 28, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Calorimetry, Differential Scanning; Chitosan; Drug Delivery Systems; Eye; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Timolol; Tissue Adhesives; Water

2012
Nanoparticles biodistribution in the eye.
    Oftalmologia (Bucharest, Romania : 1990), 2011, Volume: 55, Issue:4

    Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Eye; Fluorescein; In Vitro Techniques; Microscopy, Confocal; Microscopy, Electron, Scanning; Models, Animal; Nanoparticles; Oils; Ophthalmic Solutions; Pharmaceutical Vehicles; Sus scrofa; Water

2011
Mucoadhesive chitosan-dextran sulfate nanoparticles for sustained drug delivery to the ocular surface.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2013, Volume: 29, Issue:2

    Topics: Adhesives; Administration, Ophthalmic; Animals; Artemia; Chitosan; Delayed-Action Preparations; Dextran Sulfate; Drug Delivery Systems; Eye; Nanoparticles; Organ Culture Techniques; Sus scrofa

2013
Promising interaction between nanoencapsulated lutein with low molecular weight chitosan: characterization and bioavailability of lutein in vitro and in vivo.
    Food chemistry, 2013, Nov-01, Volume: 141, Issue:1

    Topics: Animals; Biological Availability; Chitosan; Drug Carriers; Drug Compounding; Eye; Humans; Liver; Lutein; Male; Mice; Molecular Weight; Nanoparticles; Particle Size; Tissue Distribution

2013
Design of an anti-inflammatory composite nanosystem and evaluation of its potential for ocular drug delivery.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Caco-2 Cells; Chitosan; Drug Carriers; Drug Delivery Systems; Eye; Humans; Indomethacin; Inflammation; Liposomes; Models, Molecular; Nanostructures; NF-kappa B; Phospholipids; Polyesters; Rabbits

2013
Chitosan nanoparticles for ocular delivery of cyclosporine A.
    Journal of microencapsulation, 2014, Volume: 31, Issue:1

    Topics: Animals; Chitosan; Cyclosporine; Delayed-Action Preparations; Eye; Immunosuppressive Agents; Nanoparticles; Sheep

2014
Design and characterization of chitosan-alginate microspheres for ocular delivery of azelastine.
    Pharmaceutical development and technology, 2014, Volume: 19, Issue:7

    Topics: Alginates; Animals; Anti-Allergic Agents; Chitosan; Conjunctivitis; Delayed-Action Preparations; Eye; Female; Glucuronic Acid; Hexuronic Acids; Microspheres; Phthalazines; Rats; Rats, Sprague-Dawley

2014
Chitosan oligosaccharides attenuate ocular inflammation in rats with experimental autoimmune anterior uveitis.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Aqueous Humor; Chitosan; Disease Models, Animal; Eye; Inflammation; Intercellular Adhesion Molecule-1; NF-kappa B; Oligosaccharides; Rats; Uveitis, Anterior

2014
Intraocular biodistribution of intravitreal injected chitosan/gelatin nanoparticles.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2014, Volume: 55, Issue:3

    Topics: Animals; Cattle; Chitosan; Eye; Fluorescence; Gelatin; Intravitreal Injections; Nanoparticles; Polymers; Rats, Wistar; Tissue Distribution

2014
Amphotericin-B entrapped lecithin/chitosan nanoparticles for prolonged ocular application.
    International journal of biological macromolecules, 2015, Volume: 72

    Topics: Adhesiveness; Amphotericin B; Animals; Antifungal Agents; Aspergillus fumigatus; Candida albicans; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Drug Stability; Eye; Instillation, Drug; Lecithins; Male; Nanoparticles; Nephelometry and Turbidimetry; Rabbits; Spectroscopy, Fourier Transform Infrared; Static Electricity

2015
Formulation and characterization of atropine sulfate in albumin-chitosan microparticles for in vivo ocular drug delivery.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:5

    Topics: Animals; Atropine; Cattle; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Cornea; Drug Delivery Systems; Eye; Humans; Microspheres; Mydriasis; Rabbits; Serum Albumin, Bovine

2015
Chitosan derivatives as effective nanocarriers for ocular release of timolol drug.
    International journal of pharmaceutics, 2015, Nov-10, Volume: 495, Issue:1

    Topics: Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Liberation; Eye; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyphosphates; Spectroscopy, Fourier Transform Infrared; Succinic Anhydrides; Timolol; X-Ray Diffraction

2015
Chitosan-based nanoparticles for rosmarinic acid ocular delivery--In vitro tests.
    International journal of biological macromolecules, 2016, Volume: 84

    Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chitosan; Cinnamates; Depsides; Drug Carriers; Drug Delivery Systems; Eye; Humans; Nanoparticles; Particle Size; Rosmarinic Acid

2016
Topical ophthalmic lipid nanoparticle formulations (SLN, NLC) of indomethacin for delivery to the posterior segment ocular tissues.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2016, Volume: 109

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cations; Chitosan; Chlorides; Cornea; Drug Carriers; Drug Delivery Systems; Excipients; Eye; Indomethacin; Lipids; Male; Nanoparticles; Nanostructures; Ophthalmic Solutions; Particle Size; Permeability; Rabbits; Sclera; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; Water

2016
Nanodispersion-loaded mucoadhesive polymeric inserts for prolonged treatment of post-operative ocular inflammation.
    Journal of microencapsulation, 2017, Volume: 34, Issue:3

    Topics: Animals; Cattle; Chitosan; Drug Delivery Systems; Eye; Inflammation; Ketorolac Tromethamine; Nanoparticles; Ophthalmic Solutions; Particle Size; Polyphosphates; Postoperative Complications; Rabbits

2017
Development of a Chitosan-based Nanoparticle Formulation for Ophthalmic Delivery of Honokiol.
    Current drug delivery, 2018, Volume: 15, Issue:4

    Topics: Administration, Ophthalmic; Animals; beta-Cyclodextrins; Biological Availability; Biphenyl Compounds; Chitosan; Drug Delivery Systems; Drug Liberation; Eye; Lignans; Nanoparticles; Particle Size; Rabbits; Surface Properties

2018
Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization.
    Expert opinion on drug delivery, 2017, Volume: 14, Issue:8

    Topics: Chitosan; Drug Liberation; Eye; Hydrogels; Neovascularization, Pathologic; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Vascular Endothelial Growth Factor A

2017
Ex Vivo and in Vivo Evaluation of the Effect of Coating a Coumarin-6-Labeled Nanostructured Lipid Carrier with Chitosan-N-acetylcysteine on Rabbit Ocular Distribution.
    Molecular pharmaceutics, 2017, 08-07, Volume: 14, Issue:8

    Topics: Acetylcysteine; Animals; Chitosan; Cornea; Coumarins; Drug Carriers; Eye; Lipids; Nanoparticles; Nanostructures; Rabbits; Thiazoles

2017
Preparation and evaluation of novel chitosan: gelrite ocular system containing besifloxacin for topical treatment of bacterial conjunctivitis: scintigraphy, ocular irritation and retention assessment.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:5

    Topics: Administration, Topical; Animals; Azepines; Chitosan; Conjunctivitis, Bacterial; Drug Carriers; Eye; Fluoroquinolones; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Rabbits; Radionuclide Imaging; Solubility; Staphylococcus aureus; Tissue Distribution

2018
Ocular anti-inflammatory activity of prednisolone acetate loaded chitosan-deoxycholate self-assembled nanoparticles.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Animals; Anti-Inflammatory Agents; Calorimetry, Differential Scanning; Chitosan; Deoxycholic Acid; Drug Carriers; Drug Liberation; Eye; Female; Guinea Pigs; Inflammation; Nanoparticles; Particle Size; Prednisolone; Spectroscopy, Fourier Transform Infrared

2019
Transscleral sustained ranibizumab delivery using an episcleral implantable device: Suppression of laser-induced choroidal neovascularization in rats.
    International journal of pharmaceutics, 2019, Aug-15, Volume: 567

    Topics: Angiogenesis Inhibitors; Animals; Chitosan; Choroidal Neovascularization; Collagen; Drug Implants; Drug Liberation; Eye; Fluorescein-5-isothiocyanate; Gelatin; Lasers; Male; Methacrylates; Polyethylene Glycols; Ranibizumab; Rats, Sprague-Dawley; Serum Albumin

2019
Covalently Cross-Linked Chitosan Hydrogel Sheet for Topical Ophthalmic Delivery of Levofloxacin.
    Journal of biomedical nanotechnology, 2018, Feb-01, Volume: 14, Issue:2

    Topics: Chitosan; Eye; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Levofloxacin; Polyethylene Glycols

2018
Exploring molecular dynamics simulation to predict binding with ocular mucin: An in silico approach for screening mucoadhesive materials for ocular retentive delivery systems.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 09-10, Volume: 309

    Topics: Administration, Ophthalmic; Amines; Animals; Cetrimonium; Chitosan; Drug Carriers; Drug Delivery Systems; Eye; Molecular Dynamics Simulation; Mucins; Pharmaceutical Preparations; Rats, Sprague-Dawley

2019
Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation.
    International journal of pharmaceutics, 2019, Oct-30, Volume: 570

    Topics: Animals; Cellulose; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Polymers; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Tissue Distribution

2019
Thermosensitive glycol chitosan-based hydrogel as a topical ocular drug delivery system for enhanced ocular bioavailability.
    International journal of pharmaceutics, 2019, Oct-30, Volume: 570

    Topics: Animals; Biological Availability; Cell Line; Chitosan; Drug Delivery Systems; Drug Liberation; Eye; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Levofloxacin; Ophthalmic Solutions; Rabbits; Temperature

2019
Functional chitosan oligosaccharide nanomicelles for topical ocular drug delivery of dexamethasone.
    Carbohydrate polymers, 2020, Jan-01, Volume: 227

    Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Chitosan; Dexamethasone; Dipeptides; Drug Delivery Systems; Drug Liberation; Epithelial Cells; Eye; Humans; Male; Micelles; Nanoparticles; Oligosaccharides; Peptide Transporter 1; Rabbits; Rats, Sprague-Dawley; Stearic Acids

2020
Mucoadhesive dexamethasone-glycol chitosan nanoparticles for ophthalmic drug delivery.
    International journal of pharmaceutics, 2020, Feb-15, Volume: 575

    Topics: Adhesiveness; Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Cell Line; Chitosan; Dexamethasone; Drug Delivery Systems; Drug Liberation; Eye; Humans; Lipopolysaccharides; Mice; Mucins; Nanoparticles; Rabbits

2020
New nanoparticles for topical ocular delivery of erythropoietin.
    International journal of pharmaceutics, 2020, Feb-25, Volume: 576

    Topics: Adhesiveness; Administration, Ophthalmic; Animals; Biological Availability; Cell Line; Chitosan; Drug Carriers; Drug Compounding; Drug Liberation; Erythropoietin; Eye; Humans; Hyaluronic Acid; Kinetics; Nanoparticles; Ophthalmic Solutions; Permeability; Recombinant Proteins; Solubility; Sus scrofa

2020
Chitosan oligosaccharide enhances binding of nanostructured lipid carriers to ocular mucins: Effect on ocular disposition.
    International journal of pharmaceutics, 2020, Mar-15, Volume: 577

    Topics: Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Coumarins; Drug Carriers; Drug Delivery Systems; Etoposide; Eye; Lipids; Mucins; Nanostructures; Oligosaccharides; Rabbits; Rats; Rats, Sprague-Dawley; Tissue Distribution; Toxicity Tests

2020
Clarithromycin-Loaded Ocular Chitosan Nanoparticle: Formulation, Optimization, Characterization, Ocular Irritation, and Antimicrobial Activity.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Adhesiveness; Animals; Anti-Bacterial Agents; Chitosan; Clarithromycin; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Eye; Nanoparticles; Particle Size

2020
Smart polymeric eye gear: A possible preventive measure against ocular transmission of COVID-19.
    Medical hypotheses, 2020, Volume: 144

    Topics: Administration, Topical; Angiotensin-Converting Enzyme 2; Biopolymers; Chitosan; COVID-19; Dendrimers; Dextrans; Eye; Heparin; Humans; Hyaluronic Acid; Ophthalmic Solutions; Personal Protective Equipment; Polymers; Polysaccharides; Risk Factors

2020
Glycol chitosan/oxidized hyaluronic acid hydrogel film for topical ocular delivery of dexamethasone and levofloxacin.
    International journal of biological macromolecules, 2021, Jan-15, Volume: 167

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chemical Phenomena; Chitosan; Cornea; Dexamethasone; Drug Carriers; Drug Delivery Systems; Drug Liberation; Eye; Hyaluronic Acid; Hydrogels; Levofloxacin; Mice; Microbial Sensitivity Tests; Molecular Structure; Oxidation-Reduction; RAW 264.7 Cells

2021
A Novel Carbon Dots/Thermo-Sensitive In Situ Gel for a Composite Ocular Drug Delivery System: Characterization, Ex-Vivo Imaging, and In Vivo Evaluation.
    International journal of molecular sciences, 2021, Sep-14, Volume: 22, Issue:18

    Topics: Animals; Aqueous Humor; Carbon; Cell Death; Chitosan; Diclofenac; Drug Delivery Systems; Drug Liberation; Eye; Gels; Hyaluronic Acid; Irritants; Nanoparticles; Ophthalmic Solutions; Photoelectron Spectroscopy; Rabbits; Spectroscopy, Fourier Transform Infrared; Temperature

2021