Page last updated: 2024-08-25

chitosan and atorvastatin

chitosan has been researched along with atorvastatin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's12 (66.67)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Banerjee, R; Basu, AK; Chatterjee, N; Guha, S; Pal, S; Pal, SK; Sarkar, G1
Beskonakli, E; Bodur, E; Eroglu, H; Nacar, O; Nemutlu, E; Oner, L; Sargon, MF; Turkoglu, OF1
Ahmad, FJ; Akhter, S; Anwar, M; Gahoi, S; Jain, GK; Khar, RK; Mallick, N; Talegaonkar, S; Warsi, MH1
Choi, H; Lee, H; Lee, J; Lee, MK1
Awad, GA; Kamel, AO; Mekhail, GM; Mortada, ND1
Cai, K; Hu, Y; Luo, Z; Xie, D1
Bariwal, J; Garg, T; Goyal, AK; Rath, G; Rohilla, R1
Abdelaal, MY; El-Helw, AM; Kurakula, M; Sobahi, TR1
Ahmed, TA; Kurakula, M1
J B, VK; Madhusudhan, B; Ramakrishna, S1
Akca, G; Işılay Özdoğan, A; Şenel, S1
Akca, G; Comerdov, E; İlarslan, YD; Iskit, AB; Kösemehmetoğlu, K; Kutlu, HB; Özdoğan, AI; Şenel, S1
Abdel-Halim, M; Asimakopoulou, A; Hassan, R; Mansour, S; Safy, SE; Tammam, SN; Weiskirchen, R1
Arafa, MG; El-Dahan, MS; Girgis, GNS1
Anton, N; Batool, F; Benkirane-Jessel, N; Huck, O; Klymchenko, A; Petit, C; Stutz, C; Vandamme, T1
Bagheri, F; Darakhshan, S; Mazloomi, S; Shiri Varnamkhasti, B; Tahvilian, R1
Biswal, J; Chandra, A; Dash, R; Goel, VK; Mohapatra, S; Prusty, SK; Sharma, T; Yadav, M1
Al-Okbi, SY; Ali, O; Aly, AS; Elbakry, HFH; Esmail, RSH; Refaat, D1

Trials

1 trial(s) available for chitosan and atorvastatin

ArticleYear
Effect of chitosan on lipid levels when administered concurrently with atorvastatin--a placebo controlled study.
    Journal of the Indian Medical Association, 2005, Volume: 103, Issue:8

    Topics: Anticholesteremic Agents; Atorvastatin; Chitosan; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Pyrroles

2005

Other Studies

17 other study(ies) available for chitosan and atorvastatin

ArticleYear
A quadruped study on chitosan microspheres containing atorvastatin calcium: preparation, characterization, quantification and in-vivo application.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:9

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Chitosan; Heptanoic Acids; Interleukin-1beta; Interleukin-6; Lipid Peroxidation; Microspheres; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Wounds and Injuries

2010
Enhanced bioavailability of nano-sized chitosan-atorvastatin conjugate after oral administration to rats.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Oct-09, Volume: 44, Issue:3

    Topics: Adhesiveness; Administration, Oral; Animals; Atorvastatin; Biological Availability; Chitosan; Chromatography, High Pressure Liquid; Drug Compounding; Drug Stability; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Mucosa; Intestine, Small; Microscopy, Electron, Scanning; Molecular Structure; Nanoconjugates; Particle Size; Pyrroles; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties

2011
Polymer-directed crystallization of atorvastatin.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:8

    Topics: Anticholesteremic Agents; Atorvastatin; Cellulose; Chitosan; Crystallization; Drug Stability; Heptanoic Acids; Models, Molecular; Polyethylene Glycols; Polymers; Powder Diffraction; Pyrroles; Solubility; X-Ray Diffraction

2012
Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan.
    International journal of biological macromolecules, 2012, Volume: 51, Issue:4

    Topics: Antineoplastic Agents; Atorvastatin; Capsules; Chitosan; Delayed-Action Preparations; Drug Carriers; HCT116 Cells; Heptanoic Acids; Humans; MCF-7 Cells; Micelles; Nanostructures; Particle Size; Polymers; Pyrroles; Stearic Acids

2012
Surface engineering of titanium substrates with chitosan-atorvastatin conjugate for reduced inflammation responses and improved cytocompatibility.
    Journal of biomedical materials research. Part A, 2013, Volume: 101, Issue:7

    Topics: Acid Phosphatase; Animals; Atorvastatin; Biocompatible Materials; Cells, Immobilized; Chitosan; Cytokines; Dogs; Fluorescent Antibody Technique; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; L-Lactate Dehydrogenase; Macrophages; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Nitric Oxide; Proteins; Pyrroles; Reactive Oxygen Species; Surface Properties; Titanium

2013
Development, optimization and characterization of glycyrrhetinic acid-chitosan nanoparticles of atorvastatin for liver targeting.
    Drug delivery, 2016, Volume: 23, Issue:7

    Topics: Atorvastatin; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Liver; Nanoparticles; Particle Size

2016
Chitosan based atorvastatin nanocrystals: effect of cationic charge on particle size, formulation stability, and in-vivo efficacy.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Atorvastatin; Cations; Chitosan; Drug Stability; Hypolipidemic Agents; Lipids; Male; Nanoparticles; Particle Size; Rats, Wistar

2015
Co-Delivery of Atorvastatin Nanocrystals in PLGA based in situ Gel for Anti-Hyperlipidemic Efficacy.
    Current drug delivery, 2016, Volume: 13, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Liberation; Gels; Hyperlipidemias; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Surface Properties; X-Ray Diffraction

2016
Preparation and characterisation of atorvastatin and curcumin-loaded chitosan nanoformulations for oral delivery in atherosclerosis.
    IET nanobiotechnology, 2017, Volume: 11, Issue:1

    Topics: Administration, Oral; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Chitosan; Curcumin; Delayed-Action Preparations; Diffusion; Drug Combinations; Drug Compounding; Humans; Nanocapsules; Particle Size

2017
Development and in vitro evaluation of chitosan based system for local delivery of atorvastatin for treatment of periodontitis.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Nov-01, Volume: 124

    Topics: Anti-Inflammatory Agents; Atorvastatin; Chitosan; Cytokines; Drug Delivery Systems; Drug Liberation; Fibroblasts; Gels; Gingiva; Humans; Periodontitis; Viscosity

2018
In vivo evaluation of chitosan based local delivery systems for atorvastatin in treatment of periodontitis.
    International journal of pharmaceutics, 2018, Oct-25, Volume: 550, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Chitosan; Cytokines; Drug Delivery Systems; Male; Periodontitis; Rats, Wistar

2018
Prevention of hepatic stellate cell activation using JQ1- and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 134

    Topics: Actins; Animals; Atorvastatin; Azepines; Carbon Tetrachloride; Chitosan; Disease Models, Animal; Drug Carriers; Drug Evaluation, Preclinical; Drug Synergism; HEK293 Cells; Hepatic Stellate Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Mice; Nanoparticles; Nuclear Proteins; Transcription Factors; Treatment Outcome; Triazoles; Vitamin A

2019
Chitosan-Coated PLGA Nanoparticles for Enhanced Ocular Anti-Inflammatory Efficacy of Atorvastatin Calcium.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Atorvastatin; Biocompatible Materials; Biological Availability; Chitosan; Drug Carriers; Drug Delivery Systems; Eye Diseases; Gels; Inflammation; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits

2020
Development of a thermosensitive statin loaded chitosan-based hydrogel promoting bone healing.
    International journal of pharmaceutics, 2020, Aug-30, Volume: 586

    Topics: Animals; Atorvastatin; Bone Regeneration; Cells, Cultured; Chitosan; Epithelial Cells; Fibroblasts; Gingiva; Humans; Hydrogels; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mice; Mice, Inbred C57BL; Porphyromonas gingivalis

2020
Dual loading of
    Drug development and industrial pharmacy, 2021, Volume: 47, Issue:4

    Topics: Atorvastatin; Carboxymethylcellulose Sodium; Chitosan; Nanogels; Plant Oils; Polyethylene Glycols; Polyethyleneimine; Staphylococcus aureus

2021
Modeling of chitosan modified PLGA atorvastatin-curcumin conjugate (AT-CU) nanoparticles, overcoming the barriers associated with PLGA: An approach for better management of atherosclerosis.
    International journal of pharmaceutics, 2023, Jun-10, Volume: 640

    Topics: Animals; Atherosclerosis; Atorvastatin; Chitosan; Copper; Curcumin; Drug Carriers; Glycols; Mice; Nanoparticles; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer

2023
Management of metabolic syndrome by nutraceuticals prepared from chitosan and ferulic acid with or without beta-sitosterol and their nanoforms.
    Scientific reports, 2023, 07-27, Volume: 13, Issue:1

    Topics: Animals; Atorvastatin; Chitosan; Diet, High-Fat; Dietary Supplements; Fructose; Insulin Resistance; Metabolic Syndrome; Rats

2023