Page last updated: 2024-08-25

chitosan and acyclovir

chitosan has been researched along with acyclovir in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.71)18.2507
2000's10 (28.57)29.6817
2010's15 (42.86)24.3611
2020's8 (22.86)2.80

Authors

AuthorsStudies
Conti, B; Genta, I; Pavanetto, F; Perugini, P; Puglisi, G; Spadaro, A1
Conti, B; Genta, I; Modena, T; Muzzarelli, RA; Pavanetto, F; Perugini, P1
Bonferoni, MC; Caramella, C; Ferrari, F; Rossi, S; Sandri, G1
Bonferoni, MC; Caramella, C; Ferrari, F; Muzzarelli, C; Rossi, S; Sandri, G1
Hippalgaonkar, K; Majumdar, S; Repka, MA1
Bonferoni, MC; Caramella, C; Ferrari, F; Gibin, S; Rossi, S; Sandri, G1
Bagchi, T; Jogani, V; Mishra, AK; Mishra, P; Misra, A; Shah, P1
Dhaliwal, S; Jain, S; Singh, HP; Tiwary, AK1
Laranjeira, MC; Murakami, FS; Silva, MA; Stulzer, HK; Tagliari, MP1
Al-Robayan, AA; Alanazi, FK; Alsarra, IA; El Maghraby, GM; Hamed, AY; Mahrous, GM1
Christoffersen, C; El-Kattan, A; Merzlikine, A; Poe, J; Rago, B; Rotter, C; Thomas, VH; Troutman, M1
Hasanovic, A; Reznicek, G; Valenta, C; Zehl, M1
Fischinger, K; Hasanovic, A; Hollick, C; Valenta, C1
Refai, H; Tag, R1
Hasanovic, A; Resch, GP; Valenta, C; Winkler, R1
Aiba, T; Goto, Y; Kurosaki, Y; Masuda, A1
Gago-Guillan, M; Otero-Espinar, FJ; Ruiz-Caro, R; Veiga, MD1
Adriaens, E; Calderón, L; Cordoba-Diaz, D; Cordoba-Diaz, M; Elorza, B; Elorza, M; Harris, R; Heras, A; Lenoir, J; Remon, JP1
Al-Kassas, R; Chalabi, S; In Kim, JH; Langford, C; Painter, S; Seyfoddin, A; Svirskis, D1
Kubbinga, M; Langguth, P; Nguyen, MA; Staubach, P; Teerenstra, S1
Ahmed, TA; Al-Subaie, MM; Aljaeid, BM; El-Say, KM; Hosny, KM1
Abad, MJ; Bedoya, LM; Bermejo, P; Carro, R; Fernández-Ferreiro, A; Martín-Illana, A; Otero-Espinar, F; Rubio, J; Ruiz-Caro, R; Sánchez-Sánchez, MP; Tamayo, A; Veiga, MD1
Srinivas, NR1
Al-Kassas, R; McGhee, CN; Patel, DV; Rupenthal, ID; Seyfoddin, A; Sherwin, T; Taylor, JA1
Ates, M; Kaynak, MS; Sahin, S1
Augustijns, P; García, MA; Heinen, C; Kubbinga, M; Langguth, P; Verwei, M; Wortelboer, HM1
Adnan, S; Hanif, M; Ranjha, NM1
Amirian, J; Du, B; Shekh, MI; Stadler, FJ; Zhu, Y1
Argenziano, M; Bastiancich, C; Cavalli, R; Civra, A; Donalisio, M; Lembo, D; Rittà, M1
Bou-Chacra, NA; Consiglieri, VO; Gonçalves, JE; Löbenberg, R; Monteiro, LM; Storpirtis, S; Tavares, GD1
Chien, TC; Hilles, AR; Kiong, KC; Mahmood, S; Tham, CS; Venugopal, JR1
Deshkar, S; Kale, R; Sikchi, S; Thakre, A1
Ahmad, M; Alqahtani, MS; Barkat, K; Khan, MT; Mahmood, A; Malik, NS; Rashid, A; Tulain, UR1
Abd-Elsalam, WH; Ibrahim, RR1
Al-Gousous, J; García, MA; Hensler, G; Langguth, P; Lennernäs, H; Pielenhofer, J; Wagner, M1

Reviews

1 review(s) available for chitosan and acyclovir

ArticleYear
Microparticulate drug delivery systems.
    EXS, 1999, Volume: 87

    Topics: Acyclovir; Animals; Antiviral Agents; Biocompatible Materials; Capsules; Chitin; Chitosan; Drug Carriers

1999

Trials

1 trial(s) available for chitosan and acyclovir

ArticleYear
The Influence of Chitosan on the Oral Bioavailability of Acyclovir--a Comparative Bioavailability Study in Humans.
    Pharmaceutical research, 2015, Volume: 32, Issue:7

    Topics: Acyclovir; Administration, Oral; Adult; Antiviral Agents; Biological Availability; Chitosan; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Drug Carriers; Female; Healthy Volunteers; Humans; Male

2015

Other Studies

33 other study(ies) available for chitosan and acyclovir

ArticleYear
Bioadhesive microspheres for ophthalmic administration of acyclovir.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:8

    Topics: Acyclovir; Adhesives; Animals; Antiviral Agents; Aqueous Humor; Biological Availability; Chemistry, Pharmaceutical; Chitin; Chitosan; Cross-Linking Reagents; Drug Delivery Systems; Female; Microspheres; Ophthalmic Solutions; Photomicrography; Rabbits; X-Ray Diffraction

1997
Buccal delivery of acyclovir from films based on chitosan and polyacrylic acid.
    Pharmaceutical development and technology, 2003, Volume: 8, Issue:2

    Topics: Absorption; Acrylic Resins; Acyclovir; Adhesiveness; Administration, Oral; Animals; Antimetabolites; Cheek; Chitin; Chitosan; Drug Delivery Systems; Excipients; In Vitro Techniques; Mouth Mucosa; Nephelometry and Turbidimetry; Swine; Viscosity

2003
Assessment of chitosan derivatives as buccal and vaginal penetration enhancers.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 21, Issue:2-3

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Buccal; Administration, Intravaginal; Animals; Area Under Curve; Chitosan; Female; Models, Biological; Molecular Weight; Mouth Mucosa; Permeability; Pharmaceutical Solutions; Polymers; Pyrrolidinones; Swine; Time Factors; Vagina

2004
Effect of chitosan, benzalkonium chloride and ethylenediaminetetraacetic acid on permeation of acyclovir across isolated rabbit cornea.
    International journal of pharmaceutics, 2008, Feb-04, Volume: 348, Issue:1-2

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Animals; Antiviral Agents; Benzalkonium Compounds; Chitosan; Cornea; Drug Synergism; Edetic Acid; In Vitro Techniques; Male; Permeability; Rabbits

2008
Chitosan citrate as multifunctional polymer for vaginal delivery. Evaluation of penetration enhancement and peptidase inhibition properties.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2008, Feb-05, Volume: 33, Issue:2

    Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Intravaginal; Animals; Biological Availability; Caco-2 Cells; Carboxypeptidases A; Cell Survival; Chitosan; Ciprofloxacin; Dextrans; Fluorescein-5-isothiocyanate; Humans; Intestinal Absorption; Leucyl Aminopeptidase; Mucous Membrane; Protease Inhibitors; Sus scrofa; Vaginal Creams, Foams, and Jellies; Viscosity

2008
In vitro assessment of acyclovir permeation across cell monolayers in the presence of absorption enhancers.
    Drug development and industrial pharmacy, 2008, Volume: 34, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; beta-Cyclodextrins; Biological Transport; Caco-2 Cells; Cell Line; Cell Survival; Chitosan; Dogs; Drug Synergism; Electric Impedance; Excipients; Humans; Kidney; Mannitol; Permeability; Sodium Dodecyl Sulfate

2008
Mucoadhesive microspheres for gastroretentive delivery of acyclovir: in vitro and in vivo evaluation.
    The AAPS journal, 2008, Volume: 10, Issue:2

    Topics: Acrylates; Acyclovir; Administration, Oral; Animals; Antiviral Agents; Chitosan; Drug Carriers; Gastric Mucosa; In Vitro Techniques; Intestinal Mucosa; Methylcellulose; Microspheres; Particle Size; Rats; Rats, Sprague-Dawley; Solubility; Surface Properties; Swine; Tissue Adhesives; Tissue Distribution

2008
Development and validation of an RP-HPLC method to quantitate acyclovir in cross-linked chitosan microspheres produced by spray drying.
    Journal of chromatographic science, 2008, Volume: 46, Issue:6

    Topics: Acyclovir; Antiviral Agents; Chitosan; Chromatography, High Pressure Liquid; Microspheres; Reference Standards; Reproducibility of Results; Sensitivity and Specificity

2008
Mucoadhesive polymeric hydrogels for nasal delivery of acyclovir.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:3

    Topics: Acrylates; Acyclovir; Adhesiveness; Administration, Intranasal; Animals; Chitosan; Cross-Linking Reagents; Drug Carriers; Excipients; Glycerol; Hydrogels; Nasal Mucosa; Polyethylene Glycols; Povidone; Sheep; Technology, Pharmaceutical

2009
Effect of chitosan glutamate, carbomer 974P, and EDTA on the in vitro Caco-2 permeability and oral pharmacokinetic profile of acyclovir in rats.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:9

    Topics: Acrylates; Acyclovir; Animals; Antiviral Agents; Area Under Curve; Caco-2 Cells; Cell Membrane Permeability; Chemistry, Pharmaceutical; Chitosan; Chromatography, High Pressure Liquid; Edetic Acid; Electric Impedance; Excipients; Glutamates; Humans; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley

2009
Chitosan-tripolyphosphate nanoparticles as a possible skin drug delivery system for aciclovir with enhanced stability.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:12

    Topics: Acyclovir; Antiviral Agents; Calorimetry; Chitosan; Drug Carriers; Drug Stability; Gels; Humans; Lipid Bilayers; Nanoparticles; Particle Size; Permeability; Polyphosphates; Skin; Skin Absorption; Temperature

2009
Improvement in physicochemical parameters of DPPC liposomes and increase in skin permeation of aciclovir and minoxidil by the addition of cationic polymers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 75, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Acyclovir; Animals; Calorimetry, Differential Scanning; Cations; Chitosan; Hydrogen Bonding; In Vitro Techniques; Liposomes; Minoxidil; Particle Size; Phase Transition; Polymers; Polymethacrylic Acids; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Swine

2010
Development and characterization of sponge-like acyclovir ocular minitablets.
    Drug delivery, 2011, Volume: 18, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Chemistry, Pharmaceutical; Chitosan; Columbidae; Delayed-Action Preparations; Eye; Freeze Drying; Gels; Keratitis, Herpetic; Particle Size; Polymers; Rabbits; Simplexvirus; Tablets; Viscosity; Vision, Ocular

2011
Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2011, Volume: 79, Issue:1

    Topics: Abdomen; Acyclovir; Animals; Antiviral Agents; Biocompatible Materials; Chitosan; Drug Compounding; Drug Delivery Systems; Drug Evaluation, Preclinical; Ear; Epidermis; Humans; Lipids; Liposomes; Permeability; Skin; Skin Absorption; Spectroscopy, Fourier Transform Infrared; Swine; Water Loss, Insensible

2011
In vivo application of chitosan to facilitate intestinal acyclovir absorption in rats.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:7

    Topics: Acyclovir; Animals; Antiviral Agents; Chitosan; Glycoside Hydrolases; Intestinal Absorption; Jejunum; Male; Pharmaceutical Vehicles; Rats; Rats, Wistar; Streptomyces; Viscosity

2012
Mucoadhesive tablets for controlled release of acyclovir.
    Chemical & pharmaceutical bulletin, 2012, Volume: 60, Issue:10

    Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Chitosan; Delayed-Action Preparations; Gastric Mucosa; Humans; Hypromellose Derivatives; Methylcellulose; Swine; Tablets; Tissue Adhesives

2012
Nano and microparticulate chitosan-based systems for antiviral topical delivery.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Jan-23, Volume: 48, Issue:1-2

    Topics: Acyclovir; Administration, Topical; Alkaline Phosphatase; Animals; Antiviral Agents; Chitosan; Drug Delivery Systems; Gastropoda; L-Lactate Dehydrogenase; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Spectroscopy, Fourier Transform Infrared; Toxicity Tests, Acute; X-Ray Diffraction

2013
Development of mucoadhesive floating hollow beads of acyclovir with gastroretentive properties.
    Pharmaceutical development and technology, 2014, Volume: 19, Issue:5

    Topics: Acyclovir; Adhesiveness; Administration, Oral; Animals; Antiviral Agents; Chemistry, Pharmaceutical; Chickens; Chitosan; Delayed-Action Preparations; Humans

2014
Utilization of nanotechnology to enhance percutaneous absorption of acyclovir in the treatment of herpes simplex viral infections.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Acyclovir; Animals; Biological Availability; Chitosan; Eugenol; Herpes Simplex; Hydrogels; Male; Models, Theoretical; Molecular Weight; Nanoparticles; Nanotechnology; Particle Size; Rats; Rats, Wistar; Skin; Skin Absorption

2015
Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation.
    Marine drugs, 2015, Sep-18, Volume: 13, Issue:9

    Topics: Acyclovir; Carrageenan; Cell Line; Cell Survival; Chitosan; Herpes Genitalis; Humans

2015
The Interesting Case of Acyclovir Delivered Using Chitosan in Humans: Is it a Drug Issue or Formulation Issue?
    Pharmaceutical research, 2016, Volume: 33, Issue:3

    Topics: Acyclovir; Adhesiveness; Administration, Oral; Biological Availability; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Excipients; Humans; Intestinal Absorption; Permeability; Terfenadine

2016
Ex vivo and In vivo Evaluation of Chitosan Coated Nanostructured Lipid Carriers for Ocular Delivery of Acyclovir.
    Current drug delivery, 2016, Volume: 13, Issue:6

    Topics: Acyclovir; Administration, Ophthalmic; Biological Availability; Chitosan; Cornea; Drug Carriers; Nanostructures

2016
Effect of permeability enhancers on paracellular permeability of acyclovir.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:6

    Topics: Acyclovir; Administration, Oral; Animals; beta-Cyclodextrins; Biological Availability; Chitosan; Colon; Decanoic Acids; Drug Compounding; Excipients; Female; Ileum; Intestinal Absorption; Jejunum; Perfusion; Permeability; Rats, Sprague-Dawley; Sodium Dodecyl Sulfate

2016
The effect of chitosan on the bioaccessibility and intestinal permeability of acyclovir.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 136

    Topics: Acyclovir; Animals; Antiviral Agents; Biocompatible Materials; Caco-2 Cells; Chitosan; Drug Interactions; Humans; Intestinal Absorption; Jejunum; Organ Culture Techniques; Permeability; Rats; Swine

2019
Synthesis of N,O-Carboxymethyated chitosan and its application in the development of acyclovir loaded nanoparticles.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:5(Suppleme

    Topics: Acyclovir; Chitosan; Drug Carriers; Drug Liberation; Microscopy, Electron, Scanning; Nanoparticles; Solubility; Spectroscopy, Fourier Transform Infrared

2019
Oxidized chitosan modified electrospun scaffolds for controllable release of acyclovir.
    International journal of biological macromolecules, 2020, May-15, Volume: 151

    Topics: Acyclovir; Antiviral Agents; Cell Proliferation; Chitosan; Drug Carriers; Drug Liberation; Humans; Kinetics; Magnetic Resonance Spectroscopy; Nanofibers; Oxidation-Reduction; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; Tissue Scaffolds; X-Ray Diffraction

2020
Acyclovir-loaded sulfobutyl ether-β-cyclodextrin decorated chitosan nanodroplets for the local treatment of HSV-2 infections.
    International journal of pharmaceutics, 2020, Sep-25, Volume: 587

    Topics: Acyclovir; Antiviral Agents; beta-Cyclodextrins; Chitosan; Ethers; Female; Herpesvirus 2, Human; Humans

2020
N,N,N-trimethylchitosan-poly (n-butylcyanoacrylate) core-shell nanoparticles as a potential oral delivery system for acyclovir.
    Colloids and surfaces. B, Biointerfaces, 2020, Volume: 196

    Topics: Acyclovir; Caco-2 Cells; Chitosan; Drug Carriers; Enbucrilate; Humans; Nanoparticles; Particle Size

2020
PEGylated Lipid Polymeric Nanoparticle-Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation.
    AAPS PharmSciTech, 2020, Oct-14, Volume: 21, Issue:7

    Topics: Acyclovir; Animals; Antiviral Agents; Chitosan; Delayed-Action Preparations; Drug Compounding; Drug Stability; Intestinal Absorption; Lecithins; Lipids; Nanoparticles; Particle Size; Polyethylene Glycols; Rabbits

2020
Poloxamer Modified Chitosan Nanoparticles for Vaginal Delivery of Acyclovir.
    Pharmaceutical nanotechnology, 2021, Volume: 9, Issue:2

    Topics: Acyclovir; Animals; Chitosan; Delivery, Obstetric; Drug Carriers; Female; HeLa Cells; Humans; Nanoparticles; Poloxamer; Pregnancy; Rats; Rats, Wistar

2021
β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation.
    Drug delivery, 2021, Volume: 28, Issue:1

    Topics: Acrylamides; Acyclovir; Animals; Antiviral Agents; Area Under Curve; beta-Cyclodextrins; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Liberation; Female; Hydrogels; Hydrogen-Ion Concentration; Metabolic Clearance Rate; Methacrylates; Rabbits; Rats; Rats, Wistar; Surface Properties

2021
Span 80/TPGS modified lipid-coated chitosan nanocomplexes of acyclovir as a topical delivery system for viral skin infections.
    International journal of pharmaceutics, 2021, Nov-20, Volume: 609

    Topics: Acyclovir; Chitosan; Drug Carriers; Drug Delivery Systems; Hexoses; Lipids; Nanoparticles; Particle Size; Vitamin E

2021
Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus.
    Drug metabolism and pharmacokinetics, 2023, Volume: 49

    Topics: Acyclovir; Chitosan; Excipients; Food-Drug Interactions; Humans; Intestinal Absorption; Mucus

2023