chiniofon has been researched along with thiosemicarbazide* in 1 studies
1 other study(ies) available for chiniofon and thiosemicarbazide
| Article | Year |
|---|---|
Anti-Prostate Cancer Activity of 8-Hydroxyquinoline-2-Carboxaldehyde-Thiosemicarbazide Copper Complexes by Fluorescent Microscopic Imaging.
Copper 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide (CuHQTS) and copper 8-hydroxyquinoline-2-carboxaldehyde-4,4-dimethyl-3-thiosemicarbazide (CuHQDMTS) are two copper thiosemicarbazone complexes with potent anticancer activity on cisplatin-resistant neuroblastoma cells. This study aimed to evaluate anti-prostate cancer activity of these two copper complexes in vitro. Both CuHQTS and CuHQDMTS inhibited proliferation of prostate cancer cells and showed cytotoxicity on prostate cancer cells carrying green fluorescent protein (GFP) by fluorescent microscopic imaging. The findings of this study demonstrated anti-prostate cancer activity of CuHQTS and CuHQDMTS and suggested that GFP-carrying prostate cancer cells might be used for testing anticancer activity of copper complexes by fluorescent microscopic imaging. Topics: Antineoplastic Agents; Cell Proliferation; Copper; Humans; Hydroxyquinolines; Image Processing, Computer-Assisted; Male; Microscopy, Fluorescence; Prostatic Neoplasms; Semicarbazides; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |