chiniofon and tetramic-acid

chiniofon has been researched along with tetramic-acid* in 1 studies

Other Studies

1 other study(ies) available for chiniofon and tetramic-acid

ArticleYear
Design, synthesis and in vitro evaluation of potent, novel, small molecule inhibitors of plasminogen activator inhibitor-1.
    Bioorganic & medicinal chemistry letters, 2002, Apr-08, Volume: 12, Issue:7

    We have synthesized and evaluated a series of tetramic acid-based and hydroxyquinolinone-based inhibitors of plasminogen activator inhibitor-1 (PAI-1). These studies resulted in the identification of several compounds which showed excellent potency against PAI-1. The design, synthesis and SAR of these compounds are described.

    Topics: Chromogenic Compounds; Drug Design; Drug Evaluation; Hydroxyquinolines; In Vitro Techniques; Molecular Structure; Plasminogen Activator Inhibitor 1; Pyrrolidinones; Structure-Activity Relationship

2002