chiniofon has been researched along with 10-hydroxycamptothecin* in 1 studies
1 other study(ies) available for chiniofon and 10-hydroxycamptothecin
Article | Year |
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Selective phenolic acylation of 10-hydroxycamptothecin using poly (ethylene glycol) carboxylic acid.
Selective acylation of the phenolic hydroxyl group of 10-hydroxycamptothecin has been accomplished using phenyl dichlorophosphate. Additional modification of the 10-OH as an ether permits a 20-acyl derivative to be synthesized. This result along with data from a 6-hydroxyquinoline model strongly suggests that powerful intermolecular hydrogen bonding exists in the parent molecule. Topics: Acylation; Animals; Antineoplastic Agents; Camptothecin; Carboxylic Acids; Hydrogen Bonding; Hydroxyquinolines; Indicators and Reagents; Leukemia P388; Magnetic Resonance Spectroscopy; Neoplasms; Polyethylene Glycols; Rats; Tumor Cells, Cultured | 2003 |