chenodeoxycholic acid has been researched along with simvastatin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abate, N; Bertolotti, M; Carubbi, F; Carulli, N; Digrisolo, A; Dilengite, M; Loria, P; Pinetti, A | 1 |
| De Liege, P; Gambert, P; Laurent, A; Lecoz, P; Legrand, A; Mikol, J; Peynet, J; Warnet, A | 1 |
| Bending, JJ; Leitersdorf, E; Mitchell, WD; Reshef, A; Watts, GF | 1 |
| Barkhof, F; De Graaf, R; Gabreëls, FJ; Janssen-Zijlstra, F; Keyser, A; Stalenhoef, A; Van Engelen, BG; Van Spreeken, A; Verrips, A; Wevers, RA; Wolthers, BG | 1 |
| Ko, KF; Lee, KW | 1 |
| Dotti, MT; Federico, A; Lütjohann, D; von Bergmann, K | 1 |
| Clemen, CS; Dodel, R; Klockgether, T; Lütjohann, D; Spottke, EA; Urbach, H; von Bergmann, K | 1 |
| Gadoth, N; Meiner, V; Siman-Tov, T | 1 |
| Burghaus, L; Haupt, WF; Liu, W | 1 |
| Ahrens, N; Black, A; Matysik, S; Orsó, E; Schmitz, G | 1 |
| Bosch, EP; McKinnon, JH | 1 |
| Beckx, K; Dhar, M; Eyskens, F; Luyckx, E; Simons, A; Van West, D | 1 |
1 review(s) available for chenodeoxycholic acid and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for chenodeoxycholic acid and simvastatin
| Article | Year |
|---|---|
Effect of simvastatin in addition to chenodeoxycholic acid in patients with cerebrotendinous xanthomatosis.
Topics: Adult; Anticholesteremic Agents; Chenodeoxycholic Acid; Cholesterol; Female; Gastrointestinal Agents; Humans; Kidney Function Tests; Lipids; Liver Function Tests; Male; Middle Aged; Simvastatin; Xanthomatosis, Cerebrotendinous | 1999 |
16 other study(ies) available for chenodeoxycholic acid and simvastatin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Regulation of bile acid synthesis in humans: effect of treatment with bile acids, cholestyramine or simvastatin on cholesterol 7 alpha-hydroxylation rates in vivo.
Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Deoxycholic Acid; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid | 1991 |
Cerebrotendinous xanthomatosis: treatments with simvastatin, lovastatin, and chenodeoxycholic acid in 3 siblings.
Topics: Adult; Anticholesteremic Agents; Brain Diseases; Chenodeoxycholic Acid; Female; Humans; Lovastatin; Muscular Diseases; Simvastatin; Tendons; Tomography, X-Ray Computed; Xanthomatosis | 1991 |
Cerebrotendinous xanthomatosis: a family study of sterol 27-hydroxylase mutations and pharmacotherapy.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Chenodeoxycholic Acid; Child; Child, Preschool; Cholagogues and Choleretics; Cholestanetriol 26-Monooxygenase; Cytochrome P-450 Enzyme System; England; Exons; Female; Humans; Hyperlipidemia, Familial Combined; Lovastatin; Male; Middle Aged; Musculoskeletal Diseases; Mutation; Pedigree; Simvastatin; Steroid Hydroxylases; Tendons; Xanthomatosis | 1996 |
Cerebrotendinous xanthomatosis in three siblings from a Chinese family.
Topics: Adult; Chenodeoxycholic Acid; China; Cholesterol; Genes, Recessive; Humans; Intellectual Disability; Magnetic Resonance Imaging; Male; Nuclear Family; Simvastatin; Xanthomatosis, Cerebrotendinous | 2001 |
Normalisation of serum cholestanol concentration in a patient with cerebrotendinous xanthomatosis by combined treatment with chenodeoxycholic acid, simvastatin and LDL apheresis.
Topics: Blood Component Removal; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Male; Middle Aged; Reference Values; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2004 |
Cerebrotendinous xanthomatosis: a treatable ataxia.
Topics: Adult; Cerebellar Ataxia; Cerebellum; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Disease Progression; Electroencephalography; Humans; Magnetic Resonance Imaging; Male; Paraparesis, Spastic; Peripheral Nervous System Diseases; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2005 |
Could steroids mask the diagnosis of cerebrotendinous xanthomatosis?
Topics: Achilles Tendon; Adult; Brain; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Cholestanol; Cholesterol; Diagnosis, Differential; Diagnostic Errors; Disease Progression; Down-Regulation; Humans; Male; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prednisone; Simvastatin; Steroid Hydroxylases; Steroids; Treatment Outcome; Up-Regulation; Xanthomatosis, Cerebrotendinous | 2006 |
[Cerebrotendinous xanthomatosis].
Topics: Adult; Brain; Cataract; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Dementia; Diagnosis, Differential; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2007 |
Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.
Topics: Adult; Blood Chemical Analysis; Blood Component Removal; Chenodeoxycholic Acid; Cholestenones; Follow-Up Studies; Humans; Lipoproteins, LDL; Male; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2011 |
Clinical reasoning: a case of treatable spastic paraparesis.
Topics: Adult; Anticholesteremic Agents; Chenodeoxycholic Acid; Gastrointestinal Agents; Humans; Male; Paraparesis, Spastic; Simvastatin; Xanthomatosis, Cerebrotendinous | 2012 |
Long-term follow-up on the effect of combined therapy of bile acids and statins in the treatment of cerebrotendinous xanthomatosis: a case report.
Topics: Adult; Atorvastatin; Chenodeoxycholic Acid; Cognition; Drug Therapy, Combination; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Neuropsychological Tests; Pyridines; Pyrroles; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2014 |